(cs)Fasta/(cs)Fastq
•
FASTA
¡V
Header line
¡§
>
¡¨
¡V
Sequence
•
FASTQ
¡V
Add QVs encoded as single byte ASCII codes
•
Most aligners accept FASTA/Q as input
•
Issue: data is volumous (2 bytes per base for
FASTQ)
•
Do PHRED scaled values provide the most
information?