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Background List - Definition
•To decide the degree of
enrichment, a certain background must be set up to be compared with the user¡¦s gene list.
•For example, 10% of user¡¦s genes
are kinases versus 3% of genes in human genome (this is population background) are kinases.
•Thus, the conclusion is obvious
in the particular example that the user¡¦s study is highly related to
kinase.
•However, 10% itself alone cannot
provide such a conclusion without comparing it with the
background information.