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Fold Enrichment – How to use ?
•Enrichment score of 1.3 is equivalent to non-log scale 0.05. Fold enrichment 1.5 and above are suggested to be considered as interesting.
•Caution should be taken when big fold enrichments are obtained from a small number of genes (e.g., ≤3).
This situation often happens to the terms with a few genes (more specific terms) or of smaller size (e.g.,<100) of user’s input gene list. In this case, the reliability is not as much as those fold enrichment scores obtained from larger numbers of genes