Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. RID: 1038493230-026293-13481 Query= (925 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 1,244,887 sequences; 396,357,784 total letters If you have any problems or questions with the results of this search please refer to the BLAST FAQs Taxonomy reports
RID: 1038493230-026293-13481
Query= (925 letters)
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 1,244,887 sequences; 396,357,784 total letters
If you have any problems or questions with the results of this search please refer to the BLAST FAQs
Taxonomy reports
Score E Sequences producing significant alignments: (bits) Value gi|7511475|pir||T37475 lipoprotein receptor precursor - Cae... 1800 0.0 gi|7511476|pir||T37476 lipoprotein receptor precursor - Cae... 1797 0.0 gi|25152990|ref|NP_500815.2| Receptor Mediated Endocytosis ... 1792 0.0 gi|5919205|gb|AAD56241.1|AF185706_1 yolk receptor RME-2 [Ca... 1788 0.0 gi|7507674|pir||T32559 hypothetical protein T11F8.3 - Caeno... 1438 0.0 gi|15825096|gb|AAL09567.1| lipoprotein receptor-related pro... 239 1e-61 gi|15825005|gb|AAL09566.1|AF367720_1 lipoprotein receptor-r... 239 1e-61 gi|17224416|gb|AAL36970.1| LDLR dan [Mus musculus] 238 3e-61 gi|6678720|ref|NP_032538.1| low density lipoprotein recepto... 236 1e-60 gi|4758686|ref|NP_002323.1| low density lipoprotein-related... 234 4e-60 gi|13562118|ref|NP_110454.1| low density lipoprotein recept... 229 1e-58 gi|21698928|dbj|BAC02725.1| vitellogenin receptor [Periplan... 226 1e-57 gi|6806919|ref|NP_004516.1| low density lipoprotein-related... 224 4e-57 gi|1708864|sp|P98157|LRP1_CHICK Low-density lipoprotein rec... 215 2e-54 gi|24642347|ref|NP_727914.1| CG8909-PB [Drosophila melanoga... 215 3e-54 gi|24640820|ref|NP_572563.2| CG12139-PB [Drosophila melanog... 211 5e-53 gi|17508271|ref|NP_492127.1| Low-density lipoprotein Recept... 211 6e-53 gi|21294119|gb|EAA06264.1| agCP13194 [Anopheles gambiae str... 208 2e-52 gi|21291536|gb|EAA03681.1| agCP14677 [Anopheles gambiae str... 208 4e-52 gi|21294378|gb|EAA06523.1| agCP13610 [Anopheles gambiae str... 207 4e-52 gi|7511796|pir||T18308 probable vitellogenin receptor - yel... 206 1e-51 gi|14718545|gb|AAK72954.1|AF355595_1 lipophorin receptor [A... 204 7e-51 gi|4235639|gb|AAD13300.1| low density lipoprotein receptor ... 202 2e-50 gi|3153895|gb|AAC17444.1| low density lipoprotein receptor ... 202 2e-50 gi|3201962|gb|AAC39254.1| low density lipoprotein receptor ... 202 2e-50 gi|476531|pir||QRXLL1 LDL receptor 1 precursor - African cl... 201 3e-50 gi|21294092|gb|EAA06237.1| agCP13423 [Anopheles gambiae str... 201 4e-50 gi|547838|sp|Q99087|LDL1_XENLA Low-density lipoprotein rece... 200 9e-50 gi|16519539|ref|NP_443737.1| low density lipoprotein-relate... 200 1e-49 gi|16768036|gb|AAL28237.1| GH12891p [Drosophila melanogaster] 198 3e-49 gi|9055270|ref|NP_061027.1| low density lipoprotein-related... 195 2e-48 gi|21291650|gb|EAA03795.1| ebiP6309 [Anopheles gambiae str.... 195 3e-48 gi|476532|pir||QRXLL2 LDL receptor 2 precursor - African cl... 194 5e-48 gi|16506799|gb|AAL23955.1|AF425607_1 low density lipoprotei... 193 8e-48 gi|17512511|gb|AAH19207.1| Similar to low density lipoprote... 193 9e-48 gi|2118672|pir||I48623 low density lipoprotein receptor - m... 193 1e-47 gi|25012574|gb|AAN71387.1| RE38584p [Drosophila melanogaster] 193 1e-47 gi|24586537|ref|NP_610365.1| CG8706-PA [Drosophila melanoga... 192 2e-47 gi|23600433|ref|XP_146277.2| similar to vitellogenin recept... 192 2e-47 gi|126074|sp|P20063|LDLR_RABIT Low-density lipoprotein rece... 191 3e-47 gi|24650134|ref|NP_733119.1| CG31094-PA [Drosophila melanog... 191 5e-47 gi|476530|pir||QRRTLD LDL receptor precursor - rat 188 4e-46 gi|547842|sp|P35952|LDLR_RAT Low-density lipoprotein recept... 188 4e-46 gi|547839|sp|Q99088|LDL2_XENLA Low-density lipoprotein rece... 187 8e-46 gi|1389559|gb|AAB02882.1| glycoprotein 330 186 1e-45 gi|7508146|pir||T29764 hypothetical protein T21E3.3 - Caeno... 185 3e-45 gi|2118675|pir||JC4858 VLDL receptor precursor - African cl... 184 4e-45 gi|4128201|gb|AAD03484.1| very low density lipoprotein rece... 184 5e-45 gi|1730602|sp|P98163|YL_DROME Putative vitellogenin recepto... 184 7e-45 gi|24641935|ref|NP_511151.2| CG1372-PA [Drosophila melanoga... 184 7e-45 gi|17509113|ref|NP_491270.1| EGF-like protein [Caenorhabdit... 183 1e-44 gi|1730110|sp|P98165|LDVR_CHICK Very low-density lipoprotei... 182 1e-44 gi|17298317|gb|AAL38109.1| candidate tumor suppressor prote... 182 2e-44 gi|4504975|ref|NP_000518.1| low density lipoprotein recepto... 181 4e-44 gi|1817731|gb|AAB42184.1| low-density lipoprotein receptor ... 181 5e-44 gi|547840|sp|P35950|LDLR_CRIGR Low-density lipoprotein rece... 181 6e-44 gi|2764400|emb|CAA03855.1| lipophorin receptor [Locusta mig... 180 1e-43 gi|609533|gb|AAC37668.1| very low density lipoprotein receptor 178 4e-43 gi|6691161|gb|AAF24515.1| low density lipoprotein receptor ... 177 5e-43 gi|16610195|emb|CAD10640.1| vitellogenin receptor [Oncorhyn... 177 6e-43 gi|4507901|ref|NP_003374.1| very low density lipoprotein re... 177 6e-43 gi|437387|gb|AAA61344.1| very low density lipoprotein receptor 177 7e-43 gi|391736|dbj|BAA03946.1| very low density lipoprotein rece... 177 1e-42 gi|539705|pir||B49729 VLDL receptor short form precursor - ... 176 1e-42 gi|1595750|emb|CAA65729.1| LR8B [Gallus gallus] 176 1e-42 gi|7305629|ref|NP_038731.1| very low density lipoprotein re... 176 2e-42 gi|2118674|pir||I59603 very low density lipoprotein recepto... 176 2e-42 gi|1730112|sp|P98156|LDVR_MOUSE Very low-density lipoprotei... 175 2e-42 gi|6754526|ref|NP_034830.1| low density lipoprotein recepto... 175 3e-42 gi|15489005|gb|AAH13622.1| Similar to very low density lipo... 175 4e-42 gi|3170549|gb|AAC34396.1| LRP1 [Takifugu rubripes] 174 6e-42 gi|6981706|ref|NP_037287.1| very low density lipoprotein re... 171 3e-41 gi|17298316|gb|AAL38108.1| candidate tumor suppressor prote... 171 4e-41 gi|21288072|gb|EAA00393.1| agCP9328 [Anopheles gambiae str.... 169 1e-40 gi|18957994|gb|AAL79675.1| putative ovarian lipoprotein rec... 169 1e-40 gi|21750962|dbj|BAC03874.1| unnamed protein product [Homo s... 169 2e-40 gi|547843|sp|P35953|LDVR_RABIT Very low-density lipoprotein... 167 9e-40 gi|3449306|dbj|BAA32468.1| MEGF7 [Homo sapiens] 166 1e-39 gi|16549252|dbj|BAB70786.1| unnamed protein product [Homo s... 162 2e-38 gi|14018364|emb|CAC38356.1| ApoE receptor-2 [Mus musculus] 162 3e-38 gi|1083645|pir||S53457 dominant autoantigen gp 330 - rat (f... 161 3e-38 gi|17507419|ref|NP_491271.1| EGF-like protein [Caenorhabdit... 158 3e-37 gi|22065231|ref|XP_035037.2| similar to MEGF7 [Homo sapiens] 158 3e-37 gi|20839673|ref|XP_130248.1| similar to LDLR dan [Mus muscu... 154 7e-36 gi|4758688|ref|NP_004622.1| apolipoprotein E receptor 2, is... 148 4e-34 gi|20837077|ref|XP_130308.1| low density lipoprotein recept... 147 9e-34 gi|17298315|gb|AAL38107.1| candidate tumor suppressor prote... 143 1e-32 gi|7438663|pir||JE0237 apolipoprotein E receptor 2 precurso... 142 2e-32 gi|223684|prf||0907234A epidermal growth factor precursor 141 4e-32 gi|20341089|ref|XP_109385.1| epidermal growth factor [Mus m... 141 6e-32 gi|16716347|ref|NP_444303.1| low density lipoprotein recept... 141 6e-32 gi|50801|emb|CAA24115.1| polyprotein [Mus musculus] 141 6e-32 gi|6753732|ref|NP_034243.1| epidermal growth factor [Mus mu... 141 6e-32 gi|17389248|gb|AAH17681.1| Similar to epidermal growth fact... 141 6e-32 gi|15451866|ref|NP_059992.2| apolipoprotein E receptor 2, i... 139 3e-31 gi|1834534|emb|CAA99509.1| apolipoprotein E receptor 2 906 ... 134 5e-30 gi|15451868|ref|NP_150643.1| apolipoprotein E receptor 2, i... 131 5e-29 gi|6978797|ref|NP_036974.1| epidermal growth factor [Rattus... 129 2e-28 gi|7507774|pir||T16860 hypothetical protein T13C2.4 - Caeno... 124 6e-27 gi|4503491|ref|NP_001954.1| epidermal growth factor (beta-u... 120 6e-26 Alignments
Score E Sequences producing significant alignments: (bits) Value gi|7511475|pir||T37475 lipoprotein receptor precursor - Cae... 1800 0.0 gi|7511476|pir||T37476 lipoprotein receptor precursor - Cae... 1797 0.0 gi|25152990|ref|NP_500815.2| Receptor Mediated Endocytosis ... 1792 0.0 gi|5919205|gb|AAD56241.1|AF185706_1 yolk receptor RME-2 [Ca... 1788 0.0 gi|7507674|pir||T32559 hypothetical protein T11F8.3 - Caeno... 1438 0.0 gi|15825096|gb|AAL09567.1| lipoprotein receptor-related pro... 239 1e-61 gi|15825005|gb|AAL09566.1|AF367720_1 lipoprotein receptor-r... 239 1e-61 gi|17224416|gb|AAL36970.1| LDLR dan [Mus musculus] 238 3e-61 gi|6678720|ref|NP_032538.1| low density lipoprotein recepto... 236 1e-60 gi|4758686|ref|NP_002323.1| low density lipoprotein-related... 234 4e-60 gi|13562118|ref|NP_110454.1| low density lipoprotein recept... 229 1e-58 gi|21698928|dbj|BAC02725.1| vitellogenin receptor [Periplan... 226 1e-57 gi|6806919|ref|NP_004516.1| low density lipoprotein-related... 224 4e-57 gi|1708864|sp|P98157|LRP1_CHICK Low-density lipoprotein rec... 215 2e-54 gi|24642347|ref|NP_727914.1| CG8909-PB [Drosophila melanoga... 215 3e-54 gi|24640820|ref|NP_572563.2| CG12139-PB [Drosophila melanog... 211 5e-53 gi|17508271|ref|NP_492127.1| Low-density lipoprotein Recept... 211 6e-53 gi|21294119|gb|EAA06264.1| agCP13194 [Anopheles gambiae str... 208 2e-52 gi|21291536|gb|EAA03681.1| agCP14677 [Anopheles gambiae str... 208 4e-52 gi|21294378|gb|EAA06523.1| agCP13610 [Anopheles gambiae str... 207 4e-52 gi|7511796|pir||T18308 probable vitellogenin receptor - yel... 206 1e-51 gi|14718545|gb|AAK72954.1|AF355595_1 lipophorin receptor [A... 204 7e-51 gi|4235639|gb|AAD13300.1| low density lipoprotein receptor ... 202 2e-50 gi|3153895|gb|AAC17444.1| low density lipoprotein receptor ... 202 2e-50 gi|3201962|gb|AAC39254.1| low density lipoprotein receptor ... 202 2e-50 gi|476531|pir||QRXLL1 LDL receptor 1 precursor - African cl... 201 3e-50 gi|21294092|gb|EAA06237.1| agCP13423 [Anopheles gambiae str... 201 4e-50 gi|547838|sp|Q99087|LDL1_XENLA Low-density lipoprotein rece... 200 9e-50 gi|16519539|ref|NP_443737.1| low density lipoprotein-relate... 200 1e-49 gi|16768036|gb|AAL28237.1| GH12891p [Drosophila melanogaster] 198 3e-49 gi|9055270|ref|NP_061027.1| low density lipoprotein-related... 195 2e-48 gi|21291650|gb|EAA03795.1| ebiP6309 [Anopheles gambiae str.... 195 3e-48 gi|476532|pir||QRXLL2 LDL receptor 2 precursor - African cl... 194 5e-48 gi|16506799|gb|AAL23955.1|AF425607_1 low density lipoprotei... 193 8e-48 gi|17512511|gb|AAH19207.1| Similar to low density lipoprote... 193 9e-48 gi|2118672|pir||I48623 low density lipoprotein receptor - m... 193 1e-47 gi|25012574|gb|AAN71387.1| RE38584p [Drosophila melanogaster] 193 1e-47 gi|24586537|ref|NP_610365.1| CG8706-PA [Drosophila melanoga... 192 2e-47 gi|23600433|ref|XP_146277.2| similar to vitellogenin recept... 192 2e-47 gi|126074|sp|P20063|LDLR_RABIT Low-density lipoprotein rece... 191 3e-47 gi|24650134|ref|NP_733119.1| CG31094-PA [Drosophila melanog... 191 5e-47 gi|476530|pir||QRRTLD LDL receptor precursor - rat 188 4e-46 gi|547842|sp|P35952|LDLR_RAT Low-density lipoprotein recept... 188 4e-46 gi|547839|sp|Q99088|LDL2_XENLA Low-density lipoprotein rece... 187 8e-46 gi|1389559|gb|AAB02882.1| glycoprotein 330 186 1e-45 gi|7508146|pir||T29764 hypothetical protein T21E3.3 - Caeno... 185 3e-45 gi|2118675|pir||JC4858 VLDL receptor precursor - African cl... 184 4e-45 gi|4128201|gb|AAD03484.1| very low density lipoprotein rece... 184 5e-45 gi|1730602|sp|P98163|YL_DROME Putative vitellogenin recepto... 184 7e-45 gi|24641935|ref|NP_511151.2| CG1372-PA [Drosophila melanoga... 184 7e-45 gi|17509113|ref|NP_491270.1| EGF-like protein [Caenorhabdit... 183 1e-44 gi|1730110|sp|P98165|LDVR_CHICK Very low-density lipoprotei... 182 1e-44 gi|17298317|gb|AAL38109.1| candidate tumor suppressor prote... 182 2e-44 gi|4504975|ref|NP_000518.1| low density lipoprotein recepto... 181 4e-44 gi|1817731|gb|AAB42184.1| low-density lipoprotein receptor ... 181 5e-44 gi|547840|sp|P35950|LDLR_CRIGR Low-density lipoprotein rece... 181 6e-44 gi|2764400|emb|CAA03855.1| lipophorin receptor [Locusta mig... 180 1e-43 gi|609533|gb|AAC37668.1| very low density lipoprotein receptor 178 4e-43 gi|6691161|gb|AAF24515.1| low density lipoprotein receptor ... 177 5e-43 gi|16610195|emb|CAD10640.1| vitellogenin receptor [Oncorhyn... 177 6e-43 gi|4507901|ref|NP_003374.1| very low density lipoprotein re... 177 6e-43 gi|437387|gb|AAA61344.1| very low density lipoprotein receptor 177 7e-43 gi|391736|dbj|BAA03946.1| very low density lipoprotein rece... 177 1e-42 gi|539705|pir||B49729 VLDL receptor short form precursor - ... 176 1e-42 gi|1595750|emb|CAA65729.1| LR8B [Gallus gallus] 176 1e-42 gi|7305629|ref|NP_038731.1| very low density lipoprotein re... 176 2e-42 gi|2118674|pir||I59603 very low density lipoprotein recepto... 176 2e-42 gi|1730112|sp|P98156|LDVR_MOUSE Very low-density lipoprotei... 175 2e-42 gi|6754526|ref|NP_034830.1| low density lipoprotein recepto... 175 3e-42 gi|15489005|gb|AAH13622.1| Similar to very low density lipo... 175 4e-42 gi|3170549|gb|AAC34396.1| LRP1 [Takifugu rubripes] 174 6e-42 gi|6981706|ref|NP_037287.1| very low density lipoprotein re... 171 3e-41 gi|17298316|gb|AAL38108.1| candidate tumor suppressor prote... 171 4e-41 gi|21288072|gb|EAA00393.1| agCP9328 [Anopheles gambiae str.... 169 1e-40 gi|18957994|gb|AAL79675.1| putative ovarian lipoprotein rec... 169 1e-40 gi|21750962|dbj|BAC03874.1| unnamed protein product [Homo s... 169 2e-40 gi|547843|sp|P35953|LDVR_RABIT Very low-density lipoprotein... 167 9e-40 gi|3449306|dbj|BAA32468.1| MEGF7 [Homo sapiens] 166 1e-39 gi|16549252|dbj|BAB70786.1| unnamed protein product [Homo s... 162 2e-38 gi|14018364|emb|CAC38356.1| ApoE receptor-2 [Mus musculus] 162 3e-38 gi|1083645|pir||S53457 dominant autoantigen gp 330 - rat (f... 161 3e-38 gi|17507419|ref|NP_491271.1| EGF-like protein [Caenorhabdit... 158 3e-37 gi|22065231|ref|XP_035037.2| similar to MEGF7 [Homo sapiens] 158 3e-37 gi|20839673|ref|XP_130248.1| similar to LDLR dan [Mus muscu... 154 7e-36 gi|4758688|ref|NP_004622.1| apolipoprotein E receptor 2, is... 148 4e-34 gi|20837077|ref|XP_130308.1| low density lipoprotein recept... 147 9e-34 gi|17298315|gb|AAL38107.1| candidate tumor suppressor prote... 143 1e-32 gi|7438663|pir||JE0237 apolipoprotein E receptor 2 precurso... 142 2e-32 gi|223684|prf||0907234A epidermal growth factor precursor 141 4e-32 gi|20341089|ref|XP_109385.1| epidermal growth factor [Mus m... 141 6e-32 gi|16716347|ref|NP_444303.1| low density lipoprotein recept... 141 6e-32 gi|50801|emb|CAA24115.1| polyprotein [Mus musculus] 141 6e-32 gi|6753732|ref|NP_034243.1| epidermal growth factor [Mus mu... 141 6e-32 gi|17389248|gb|AAH17681.1| Similar to epidermal growth fact... 141 6e-32 gi|15451866|ref|NP_059992.2| apolipoprotein E receptor 2, i... 139 3e-31 gi|1834534|emb|CAA99509.1| apolipoprotein E receptor 2 906 ... 134 5e-30 gi|15451868|ref|NP_150643.1| apolipoprotein E receptor 2, i... 131 5e-29 gi|6978797|ref|NP_036974.1| epidermal growth factor [Rattus... 129 2e-28 gi|7507774|pir||T16860 hypothetical protein T13C2.4 - Caeno... 124 6e-27 gi|4503491|ref|NP_001954.1| epidermal growth factor (beta-u... 120 6e-26
>gi|7511475|pir||T37475 lipoprotein receptor precursor - Caenorhabditis elegans gi|4097487|gb|AAD09364.1| similar to low density lipoprotein receptor [Caenorhabditis elegans] Length = 925 Score = 1800 bits (4662), Expect = 0.0 Identities = 888/925 (96%), Positives = 888/925 (96%) Query: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC Sbjct: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 Query: 61 DKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG 120 DKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG Sbjct: 61 DKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG 120 Query: 121 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQ 180 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQ Sbjct: 121 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQ 180 Query: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ 240 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIP EKNCQ Sbjct: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPDSFLCDGDLDCDDASDEKNCQ 240 Query: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH Sbjct: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 Query: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS 360 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS Sbjct: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS 360 Query: 361 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG 420 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG Sbjct: 361 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG 420 Query: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN Sbjct: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 Query: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR Sbjct: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 Query: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN Sbjct: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 Query: 601 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG 660 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG Sbjct: 601 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG 660 Query: 661 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS 720 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS Sbjct: 661 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS 720 Query: 721 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM 780 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM Sbjct: 721 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM 780 Query: 781 EEEDSSLWXXXXXXXXXXXXXXXXXXXXXWFSQQEHMKDVISTARVRVDNMARKAEDAAA 840 EEEDSSLW WFSQQEHMKDVISTARVRVDNMARKAEDAAA Sbjct: 781 EEEDSSLWLIVLLLIFLIIVAVVGIIAFLWFSQQEHMKDVISTARVRVDNMARKAEDAAA 840 Query: 841 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE 900 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE Sbjct: 841 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE 900 Query: 901 SSTGFVRSASAPFAGVIRFENDSLL 925 SSTGFVRSASAPFAGVIRFENDSLL Sbjct: 901 SSTGFVRSASAPFAGVIRFENDSLL 925
>gi|7511476|pir||T37476 lipoprotein receptor precursor - Caenorhabditis elegans gi|4097463|gb|AAD09363.1| lipoprotein receptor precursor [Caenorhabditis elegans] Length = 925 Score = 1797 bits (4655), Expect = 0.0 Identities = 885/925 (95%), Positives = 887/925 (95%) Query: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC Sbjct: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 Query: 61 DKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG 120 DKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG Sbjct: 61 DKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG 120 Query: 121 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQ 180 SNPSAPTTF+GHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQ Sbjct: 121 SNPSAPTTFLGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQ 180 Query: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ 240 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIP EKNCQ Sbjct: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPDSFLCDGDLDCDDASDEKNCQ 240 Query: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 TNAPSEEEYLSGQADHMHSCSAAGMYSCG KGSEIGVCIPMNATCNGIKECPLGDDESKH Sbjct: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGRKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 Query: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS 360 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS Sbjct: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS 360 Query: 361 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG 420 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG Sbjct: 361 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG 420 Query: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN Sbjct: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 Query: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR Sbjct: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 Query: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN Sbjct: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 Query: 601 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG 660 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG Sbjct: 601 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG 660 Query: 661 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS 720 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS Sbjct: 661 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS 720 Query: 721 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM 780 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM Sbjct: 721 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM 780 Query: 781 EEEDSSLWXXXXXXXXXXXXXXXXXXXXXWFSQQEHMKDVISTARVRVDNMARKAEDAAA 840 EEEDSSLW WFSQQEHMKD+ISTARVRVDNMARKAEDAAA Sbjct: 781 EEEDSSLWLIVLLLIFLIIVAVVGIIAFLWFSQQEHMKDLISTARVRVDNMARKAEDAAA 840 Query: 841 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE 900 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE Sbjct: 841 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE 900 Query: 901 SSTGFVRSASAPFAGVIRFENDSLL 925 SSTGFVRSASAPFAGVIRFENDSLL Sbjct: 901 SSTGFVRSASAPFAGVIRFENDSLL 925
>gi|25152990|ref|NP_500815.2| Receptor Mediated Endocytosis 2 RME-2; Yolk receptor, LDL receptor superfamily (102.9 kD) (rme-2) [Caenorhabditis elegans] gi|23820813|gb|AAB88554.3| Receptor mediated endocytosis protein 2 [Caenorhabditis elegans] Length = 925 Score = 1792 bits (4642), Expect = 0.0 Identities = 884/925 (95%), Positives = 884/925 (95%) Query: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC Sbjct: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 Query: 61 DKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG 120 D GRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG Sbjct: 61 DNGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG 120 Query: 121 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQ 180 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGH DCSGGDDEVNCTRRGHENMQ Sbjct: 121 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHTDCSGGDDEVNCTRRGHENMQ 180 Query: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ 240 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIP EKNCQ Sbjct: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPDSFLCDGDLDCDDASDEKNCQ 240 Query: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH Sbjct: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 Query: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS 360 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS Sbjct: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS 360 Query: 361 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG 420 FACKCANGYELETDGHSCKYE TTTPEGYLFISLGGEVRQMPLADFTDGSNYS IQKFAG Sbjct: 361 FACKCANGYELETDGHSCKYETTTTPEGYLFISLGGEVRQMPLADFTDGSNYSPIQKFAG 420 Query: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN Sbjct: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 Query: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR Sbjct: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 Query: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN Sbjct: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 Query: 601 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG 660 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG Sbjct: 601 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG 660 Query: 661 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS 720 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS Sbjct: 661 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS 720 Query: 721 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM 780 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM Sbjct: 721 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM 780 Query: 781 EEEDSSLWXXXXXXXXXXXXXXXXXXXXXWFSQQEHMKDVISTARVRVDNMARKAEDAAA 840 EEEDSSLW WFSQQEHMKDVISTARVRVDNMARKAEDAAA Sbjct: 781 EEEDSSLWLIVLLLIFLIIVAVVGIIAFLWFSQQEHMKDVISTARVRVDNMARKAEDAAA 840 Query: 841 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE 900 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE Sbjct: 841 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE 900 Query: 901 SSTGFVRSASAPFAGVIRFENDSLL 925 SSTGFVRSASAPFAGVIRFENDSLL Sbjct: 901 SSTGFVRSASAPFAGVIRFENDSLL 925
>gi|5919205|gb|AAD56241.1|AF185706_1 yolk receptor RME-2 [Caenorhabditis elegans] Length = 925 Score = 1788 bits (4631), Expect = 0.0 Identities = 882/925 (95%), Positives = 883/925 (95%) Query: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC Sbjct: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 Query: 61 DKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDG 120 D GRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGE+ CRDGSDEQHCEYNILKSRFDG Sbjct: 61 DNGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEEHCRDGSDEQHCEYNILKSRFDG 120 Query: 121 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQ 180 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGH DCSGGDDEVNCTRRGHENMQ Sbjct: 121 SNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHTDCSGGDDEVNCTRRGHENMQ 180 Query: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ 240 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIP EKNCQ Sbjct: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPDSFLCDGDLDCDDASDEKNCQ 240 Query: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH Sbjct: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 Query: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS 360 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS Sbjct: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGS 360 Query: 361 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG 420 FACKCANGYELETDGHSCKYE TTTPEGYLFISLGGEVRQMPLADFTDGSNYS IQKFAG Sbjct: 361 FACKCANGYELETDGHSCKYETTTTPEGYLFISLGGEVRQMPLADFTDGSNYSPIQKFAG 420 Query: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN Sbjct: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 Query: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR Sbjct: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 Query: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN Sbjct: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 Query: 601 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG 660 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG Sbjct: 601 GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTG 660 Query: 661 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS 720 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS Sbjct: 661 PPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLS 720 Query: 721 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM 780 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM Sbjct: 721 HIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFSAM 780 Query: 781 EEEDSSLWXXXXXXXXXXXXXXXXXXXXXWFSQQEHMKDVISTARVRVDNMARKAEDAAA 840 EEEDSSLW WFSQQEHMKDVISTARVRVDNMARKAEDAAA Sbjct: 781 EEEDSSLWLIVLLLIFLIIVAVVGIIAFLWFSQQEHMKDVISTARVRVDNMARKAEDAAA 840 Query: 841 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE 900 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE Sbjct: 841 PIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEVPE 900 Query: 901 SSTGFVRSASAPFAGVIRFENDSLL 925 SSTGFVRSASAPFAGVIRFENDSLL Sbjct: 901 SSTGFVRSASAPFAGVIRFENDSLL 925
>gi|7507674|pir||T32559 hypothetical protein T11F8.3 - Caenorhabditis elegans Length = 747 Score = 1438 bits (3723), Expect = 0.0 Identities = 708/747 (94%), Positives = 708/747 (94%) Query: 179 MQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKN 238 MQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIP EKN Sbjct: 1 MQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPDSFLCDGDLDCDDASDEKN 60 Query: 239 CQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES 298 CQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES Sbjct: 61 CQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES 120 Query: 299 KHCSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRL 358 KHCSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRL Sbjct: 121 KHCSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRL 180 Query: 359 GSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKF 418 GSFACKCANGYELETDGHSCKYE TTTPEGYLFISLGGEVRQMPLADFTDGSNYS IQKF Sbjct: 181 GSFACKCANGYELETDGHSCKYETTTTPEGYLFISLGGEVRQMPLADFTDGSNYSPIQKF 240 Query: 419 AGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIG 478 AGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIG Sbjct: 241 AGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIG 300 Query: 479 GNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKY 538 GNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKY Sbjct: 301 GNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKY 360 Query: 539 HRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI 598 HRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI Sbjct: 361 HRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI 420 Query: 599 SNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQ 658 SNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQ Sbjct: 421 SNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQ 480 Query: 659 TGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEK 718 TGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEK Sbjct: 481 TGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEK 540 Query: 719 LSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFS 778 LSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFS Sbjct: 541 LSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCERLNPEKFS 600 Query: 779 AMEEEDSSLWXXXXXXXXXXXXXXXXXXXXXWFSQQEHMKDVISTARVRVDNMARKAEDA 838 AMEEEDSSLW WFSQQEHMKDVISTARVRVDNMARKAEDA Sbjct: 601 AMEEEDSSLWLIVLLLIFLIIVAVVGIIAFLWFSQQEHMKDVISTARVRVDNMARKAEDA 660 Query: 839 AAPIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEV 898 AAPIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEV Sbjct: 661 AAPIVEKFRKVTDKQRSTPPREGCQTATNVDFVSYETNAEKRIRMDSSPTSYGNPMYDEV 720 Query: 899 PESSTGFVRSASAPFAGVIRFENDSLL 925 PESSTGFVRSASAPFAGVIRFENDSLL Sbjct: 721 PESSTGFVRSASAPFAGVIRFENDSLL 747
>gi|15825096|gb|AAL09567.1| lipoprotein receptor-related protein [Mus musculus] Length = 4545 Score = 239 bits (610), Expect = 1e-61 Identities = 196/706 (27%), Positives = 302/706 (42%), Gaps = 80/706 (11%) Query: 25 PAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKN 84 P V C F C +G RCIP W CD DC+ G DE+ C+ CS + C+N Sbjct: 2690 PGVKRPRC-PLNYFACPSG--RCIPMSWTCDKEDDCENGEDETHCN--KFCSEAQFECQN 2744 Query: 85 GLCVANEFKCDGEDDCRDGSDE-QHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLR 143 C++ ++ CDG DDC DGSDE HCE G C P Sbjct: 2745 HRCISKQWLCDGSDDCGDGSDEAAHCE-----------------------GKTCGPSSFS 2781 Query: 144 CRSGQ-CIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT-FFANED 201 C C+ +CDG +DC+ G DE + + +F L P F + D Sbjct: 2782 CPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHD 2841 Query: 202 NKCRSG--------YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTN---APSEEEYL 250 C G Y C + E +C + AP Sbjct: 2842 RDCADGSDESPECEYPTCGPNE--FRCANGRCLSSRQWECDGENDCHDHSDEAPKNPHCT 2899 Query: 251 SGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESK-HCSECARKR- 308 S + H C+A+ + C + G C+ CNG +C G DE H +EC ++ Sbjct: 2900 SPE----HKCNASSQFLCSS-----GRCVAEALLCNGQDDCGDGSDERGCHVNECLSRKL 2950 Query: 309 --CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCA 366 C C + G +C C+ G++L DDG TC D DEC+T C C + GS+ C C Sbjct: 2951 SGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECST-TFPCSQLCINTHGSYKCLCV 3009 Query: 367 NGYELE-TDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIR 425 GY D HSCK A T E +L + +R++ L DGSNY+ +++ G Sbjct: 3010 EGYAPRGGDPHSCK--AVTDEEPFLIFANRYYLRKLNL----DGSNYTLLKQ--GLNNAV 3061 Query: 426 SIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQ 485 ++DF +R ++ + G + ++ + + + R + +AVDW+GGN+++ Sbjct: 3062 ALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCD 3121 Query: 486 KSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMAN 545 K I + ++G + R + + R LVV G + W D + + I Sbjct: 3122 KGRDT---IEVSKLNGAY--RTVLVSSGLREPRALVVDVQNGYLYWTD-WGDHSLIGRIG 3175 Query: 546 MDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHP 605 MDGS I++D K+ P+ L +DY+ +Y+ D IE ++D R VV+S + H Sbjct: 3176 MDGSGRSIIVDTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHI 3235 Query: 606 YDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNP 665 + + F ++YW DW ++S+ T + +I T +R P + V H+L Q P++P Sbjct: 3236 FALTLFEDYVYWTDWETKSINRAHKTTGANKTLLISTLHR-PMDLHVFHALRQPDVPNHP 3294 Query: 666 CL--ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVT 709 C C LC++ P KC CP + +C+ T Sbjct: 3295 CKVNNGGCSNLCLLSPGGGH----KCACPTNFYLGGDGRTCVSNCT 3336
Score = 189 bits (481), Expect = 1e-46 Identities = 180/681 (26%), Positives = 272/681 (39%), Gaps = 108/681 (15%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC +F C NG RCI W+CDN DC DE+GCS H CS++ C +G C+ Sbjct: 976 TCFPLTQFTCNNG--RCININWRCDNDNDCGDNSDEAGCS--HSCSSTQFKCNSGRCIPE 1031 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQC 149 + CDG++DC D SDE H +R G CH +CR G C Sbjct: 1032 HWTCDGDNDCGDYSDETHANCTNQATRPPGG---------------CHSDEFQCRLDGLC 1076 Query: 150 IQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT--FFANEDNKCRSG 207 I CDG DC DE +C H+ DP F + +C S Sbjct: 1077 IPLRWRCDGDTDCMDSSDEKSC--------------EGVTHVCDPNVKFGCKDSARCISK 1122 Query: 208 YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYS 267 +C C E+NC+ A H C+ Sbjct: 1123 AWVCDGDSDC-------------EDNSDEENCEALACRPPS---------HPCA------ 1154 Query: 268 CGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKR--CDHTCMNTP-HGARCIC 324 + VC+P + C+G +C G DE + C +C+ C H C P G C C Sbjct: 1155 -----NNTSVCLPPDKLCDGKDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSC 1209 Query: 325 QEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATT 384 G +L D TC+ + CA H C C+ S C C G+ LE DG SC+ Sbjct: 1210 PLGMELGSDNHTCQIQSYCAKHLK-CSQKCDQNKFSVKCSCYEGWVLEPDGESCRSLDPF 1268 Query: 385 TPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEH 444 P ++ S E+R++ L +YS + G ++DF + ++ + E Sbjct: 1269 KP--FIIFSNRHEIRRIDLHK----GDYSVL--VPGLRNTIALDFHLSQSALYWTDVVED 1320 Query: 445 GDPTGELSVSDNGLMR----VLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMS 500 G+L DNG + V++ + +AVDWI GN+++ + + I + + Sbjct: 1321 KIYRGKL--LDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQ---IEVAKLD 1375 Query: 501 GMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLE 560 G ++ G + R + + P G++ W D RI A+M G+ R + Sbjct: 1376 GTLRTTLLAGDIEHP--RAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTIHRETGS 1433 Query: 561 --VPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNGFLY 616 P+ L +DY+ + + D I D V+ + HP+ + + G +Y Sbjct: 1434 GGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVY 1493 Query: 617 WADWGSESL-KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCL----ELEC 671 W DW + +L K + T H+ + V+ N P+ + V H Q P NPC C Sbjct: 1494 WTDWRTNTLAKANKWTGHNVT--VVQRTNTQPFDLQVYHPSRQPMAP-NPCEANGGRGPC 1550 Query: 672 PWLCVIVPKSDFIMTAKCVCP 692 LC+I ++ T C CP Sbjct: 1551 SHLCLI----NYNRTVSCACP 1567
Score = 158 bits (399), Expect = 4e-37 Identities = 184/784 (23%), Positives = 303/784 (38%), Gaps = 130/784 (16%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC + +F C N RC+P WQCD DC DE C+ CS S C NG C+A Sbjct: 3536 TC-EPYQFRCKNN--RCVPGRWQCDYDNDCGDNSDEESCT-PRPCSESEFSCANGRCIAG 3591 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCI 150 +KCDG+ DC DGSDE+ C P C + +C+SG CI Sbjct: 3592 RWKCDGDHDCADGSDEKDCT------------------------PRCDMDQFQCKSGHCI 3627 Query: 151 QPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTD-FHDDVHLVDP-TFFANEDNKCRSGY 208 CD DC G DE C G D F + L P + + ++ C Sbjct: 3628 PLRWRCDADADCMDGSDEEAC---GTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNS 3684 Query: 209 T-----------------MCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ------TNAPS 245 C + VC+ E++C+ + Sbjct: 3685 DENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTDEEDCEPPTAQNPHCKD 3744 Query: 246 EEEYLSGQADHMHSCSAAGMY-SCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSEC 304 ++E+L + S M+ CG E I T GD+ + C Sbjct: 3745 KKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASMCGDE-----ARC 3799 Query: 305 ARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACK 364 R T A C C+ G+ C+D +EC G C C + G C Sbjct: 3800 VR---------TEKAAYCACRSGFHTVPGQPGCQDINECLRFG-TCSQLCNNTKGGHLCS 3849 Query: 365 CANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTI 424 CA + ++T ++CK E + L+I+ E+R + F + + Q F G ++ Sbjct: 3850 CARNF-MKTH-NTCKAEGSEYQ--VLYIADDNEIRSL----FPGHPHSAYEQTFQGDESV 3901 Query: 425 R--SIDFMHRNNKMFM------SISDEHGDPTGELSVSDNGLMRVLRE----NVIGVS-- 470 R ++D + +++ +IS P + S+ ++ R N+ G+ Sbjct: 3902 RIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMP 3961 Query: 471 -NVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLI 529 +A+DW+ GNV++T S I + M G + +I G +VV P+RG + Sbjct: 3962 RGIAIDWVAGNVYWTD---SGRDVIEVAQMKGENRKTLISG--MIDEPHAIVVDPLRGTM 4016 Query: 530 IWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNI 589 W D + + +I A MDG+ L+ + ++ P+ LA+DY +Y+ D + +I + + Sbjct: 4017 YWSD-WGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRL 4075 Query: 590 DTKERRVVISN--GVHHPYDMAYFNGFLYWADW-GSESLKVQEMTHHHSSPQVIHTFNRY 646 + + V + G+ HP+ + F ++Y + + K+ + H SP + T Sbjct: 4076 NGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGH---SPLINLTGGLS 4132 Query: 647 PYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIP 706 V + ++ +NPC +C WLC++ P C CP+G + +C+P Sbjct: 4133 HASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSGPV-----CTCPNG--KRLDNGTCVP 4185 Query: 707 PVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDG 766 + + + + C NGG+C + C C+ Y G Sbjct: 4186 VPSPTPPPDAPRPG-----------TCTLQCFNGGSCFLNARRQPK-----CRCQPRYTG 4229 Query: 767 QYCE 770 CE Sbjct: 4230 DKCE 4233
Score = 142 bits (358), Expect = 2e-32 Identities = 107/369 (28%), Positives = 171/369 (46%), Gaps = 29/369 (7%) Query: 277 VCIPMNATCNGIKECPLGDDESKHCSE----CARKRCDHTCMNTPHGARCICQEGYKLAD 332 +C+PM+ CNGI++C G DE HC E C+R C H C+ TP G C C ++L Sbjct: 85 LCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLQA 144 Query: 333 DGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKY--EATTTPEGYL 390 DG TC+D DEC+ +G C C + GSF C C GY L+ D SCK E P L Sbjct: 145 DGKTCKDFDECSVYG-TCSQLCTNTDGSFTCGCVEGYLLQPDNRSCKAKNEPVDRPPVLL 203 Query: 391 FISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGE 450 + Q LA + G+ S I + T ++DF + N + + T Sbjct: 204 IAN-----SQNILATYLSGAQVSTITPTSTRQTT-AMDFSYANETVCWVHVGDSAAQTQL 257 Query: 451 LSVSDNGLMRVLRENVIGVS-------NVAVDWIGGNVFFTQKSPSPSAGISICTMSGMF 503 GL + E+ I +S +A+DW+ GN +F I +C +G Sbjct: 258 KCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDR---IFVCNRNGDT 314 Query: 504 CRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPS 563 C +++ + + +G+ + P G + + D Y + ++ +MDG L+D+K+ P Sbjct: 315 CVTLLD--LELYNPKGIALDPAMGKVFFTD-YGQIPKVERCDMDGQNRTKLVDSKIVFPH 371 Query: 564 ALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN-GVHHPYDMAYFNGFLYWADWGS 622 + +D + VY+ D IE V+ + K R+ +I + H Y + F +LY + S Sbjct: 372 GITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATN--S 429 Query: 623 ESLKVQEMT 631 ++ Q+ T Sbjct: 430 DNANTQQKT 438
Score = 90.9 bits (224), Expect = 8e-17 Identities = 82/302 (27%), Positives = 144/302 (47%), Gaps = 34/302 (11%) Query: 329 KLADDGLTCEDE--DECATHGHLCQHFC-EDRLGSFACKCANGYELETDGHSCKYEATTT 385 K+ D+ + E E + C+ + C C + +C C GY L + +C+ + Sbjct: 1835 KVYDESIQLEHEGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVGS-- 1892 Query: 386 PEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFM------S 439 +L S+ +R +PL D D S+ A+ +G IDF N+ ++ + Sbjct: 1893 ---FLLYSVHEGIRGIPL-DPNDKSD--ALVPVSGTSLAVGIDFHAENDTIYWVDMGLST 1946 Query: 440 ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTM 499 IS D T V NG+ R V +AVDWI GN+++T + I + + Sbjct: 1947 ISRAKRDQTWREDVVTNGIGR--------VEGIAVDWIAGNIYWTDQGFDV---IEVARL 1995 Query: 500 SGMFCRRVIEGKEQG-QSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNK 558 +G F VI QG R + VHP +G + W + + Y RI + +DG++ +L++ Sbjct: 1996 NGSFRYVVI---SQGLDKPRAITVHPEKGYLFWTE-WGHYPRIERSRLDGTERVVLVNVS 2051 Query: 559 LEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKE-RRVVISNGVHHPYDMAYFNGFLYW 617 + P+ +++DY +Y+ D IER++++T E R VV+S+ + ++ F F+YW Sbjct: 2052 ISWPNGISVDYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYW 2111 Query: 618 AD 619 +D Sbjct: 2112 SD 2113
Score = 90.5 bits (223), Expect = 1e-16 Identities = 98/367 (26%), Positives = 126/367 (34%), Gaps = 92/367 (25%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC-DKGRDESGCSYAHHCSTSFMLCKNGLC 87 NS+C EF+C NG CI CD V+ C DK ++ + C +F C NG C Sbjct: 2522 NSSCRAQDEFECANG--ECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRC 2579 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 V+N C+G DDC DGSDE C N C RCR G Sbjct: 2580 VSNMLWCNGVDDCGDGSDEIPC-----------------------NKTACGVGEFRCRDG 2616 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLV------------DPT 195 CI C+ DC DE+NC+ S+ F V V P+ Sbjct: 2617 SCIGNSSRCNQFVDCEDASDEMNCS-----TTDCSSYFRLGVKGVLFQPCERTSLCYAPS 2671 Query: 196 FFANEDN-----------------KCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKN 238 + + N +C Y C SG CIP E + Sbjct: 2672 WVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGR-CIPMSWTCDKEDDCENGEDETH 2730 Query: 239 CQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES 298 C CS A + C CI C+G +C G DE+ Sbjct: 2731 CNK-----------------FCSEA-QFECQNHR-----CISKQWLCDGSDDCGDGSDEA 2767 Query: 299 KHCSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCED-EDECATHGHLCQHFCEDR 357 HC K C + + P C+ + L D C D DE T G L C+DR Sbjct: 2768 AHCEG---KTCGPSSFSCPGTHVCVPERW--LCDGDKDCTDGADESVTAGCLYNSTCDDR 2822 Query: 358 LGSFACK 364 F C+ Sbjct: 2823 --EFMCQ 2827
Score = 82.4 bits (202), Expect = 3e-14 Identities = 92/362 (25%), Positives = 155/362 (42%), Gaps = 31/362 (8%) Query: 350 CQHFCEDRLG-SFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTD 408 C H C + +C C + +L D +C YE + +L + E+R + L D Sbjct: 1550 CSHLCLINYNRTVSCACPHLMKLHKDNTTC-YEF----KKFLLYARQMEIRGVDL----D 1600 Query: 409 GSNYSAIQKFA--GHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENV 466 Y+ I F + +D+ R +++ SD ++ G+ V+ ++ Sbjct: 1601 APYYNYIISFTVPDIDNVTVLDYDAREQRVYW--SDVRTQAIKRAFINGTGVETVVSADL 1658 Query: 467 IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMR 526 +AVDW+ N+F+T + I++ + G F V++G EQ GLVVHP+R Sbjct: 1659 PNAHGLAVDWVSRNLFWTSYDTNKKQ-INVARLDGSFKNAVVQGLEQPH---GLVVHPLR 1714 Query: 527 GLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIER 586 G + W D I MANMDGS +L + + P LAID+ +Y+ I R Sbjct: 1715 GKLYWTDG----DNISMANMDGSNHTLLFSGQ-KGPVGLAIDFPESKLYWISSGNHTINR 1769 Query: 587 VNIDTKERRVV--ISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFN 644 N+D E V+ + + + +A L+WAD SE + S + ++ Sbjct: 1770 CNLDGSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSGSVVLRNSTT 1829 Query: 645 RYPYGIAVNHSLYQTGPPSNPCL--ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTEN 702 + + S+ +NPC +C LC +P S+ T C+C GY+ + Sbjct: 1830 LVMHMKVYDESIQLEHEGTNPCSVNNGDCSQLC--LPTSE--TTRSCMCTAGYSLRSGQQ 1885 Query: 703 SC 704 +C Sbjct: 1886 AC 1887
Score = 78.6 bits (192), Expect = 4e-13 Identities = 68/274 (24%), Positives = 126/274 (45%), Gaps = 23/274 (8%) Query: 363 CKCANGYELETDGHSCKYEATTTPEGYLFISLG----GEVRQMPLADFTDGSNYSAIQKF 418 C+C +G+ L +DG SCK PE LF+ G G +R M + + I+ Sbjct: 505 CRCRSGFSLGSDGKSCK-----KPEHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENL 559 Query: 419 AGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIG 478 R++DF F+ +D G + +L++ + V VAVDW+G Sbjct: 560 MNP---RALDFHAETG--FIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWMG 614 Query: 479 GNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQ-- 536 N+++T P + ++ + + +IEGK R +VV P+ G + W D + Sbjct: 615 DNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKMTHP--RAIVVDPLNGWMYWTDWEEDP 672 Query: 537 ---KYHRIMMANMDGSQVRILLDNKLEV-PSALAIDYIRHDVYFGDVERQLIERVNIDTK 592 + R+ A MDGS I + +K + P+ L++D +Y+ D IE + ++ Sbjct: 673 KDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGT 732 Query: 593 ERRVVISN-GVHHPYDMAYFNGFLYWADWGSESL 625 +R++V ++H + + + +L+W ++ S S+ Sbjct: 733 DRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSV 766
Score = 76.6 bits (187), Expect = 2e-12 Identities = 96/362 (26%), Positives = 133/362 (36%), Gaps = 76/362 (20%) Query: 27 VNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGL 86 V+N T A +F C N +CIP W+CD DC DE C C G+ Sbjct: 3332 VSNCT---ASQFVCKND--KCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGI 3386 Query: 87 CVANEFKCDGEDDCRDGSDEQHCEYNI-LKSRFDGSNPS--APTTFVGH----------- 132 C F CDG++DC+D SDE +C+ ++ L S+F +N + P F + Sbjct: 3387 CTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDE 3446 Query: 133 -NGPE--CHPPRLRCR-SGQCIQPDLVCDGHQDCSGGDDE-VNCTRRGHENMQSSTD--- 184 + PE C P + +C + +CI VCD DC G DE NCT+ M D Sbjct: 3447 RDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQ-----MTCGVDEFR 3501 Query: 185 FHDDVHLVDPTFFANEDNKCRSG---------------YTMCHSGDVCIPXXXXXXXXXX 229 D + + + ++ C G Y + C+P Sbjct: 3502 CKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDND 3561 Query: 230 XXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIK 289 E++C SE E +SC G CI C+G Sbjct: 3562 CGDNSDEESCTPRPCSESE-----------------FSCAN-----GRCIAGRWKCDGDH 3599 Query: 290 ECPLGDDESKHCSECARKRCDHTCMNTPHGARCICQEGYKLAD-DGLTCEDEDECATHGH 348 +C G DE K C+ RCD G CI AD D + DE+ C T Sbjct: 3600 DCADGSDE-KDCT----PRCDMDQFQCKSG-HCIPLRWRCDADADCMDGSDEEACGTGVR 3653 Query: 349 LC 350 C Sbjct: 3654 TC 3655
Score = 75.1 bits (183), Expect = 4e-12 Identities = 83/333 (24%), Positives = 122/333 (36%), Gaps = 85/333 (25%) Query: 11 PLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCS 70 P+ +H+ + + P V N C + C N L +C + G D C Sbjct: 3276 PMDLHVF--HALRQPDVPNHPC-KVNNGGCSNLCLLSPGGGHKCACPTNFYLGGDGRTC- 3331 Query: 71 YAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFV 130 +C+ S +CKN C+ +KCD EDDC D SDE P P Sbjct: 3332 -VSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEP---------------PDCPEF-- 3373 Query: 131 GHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVH 190 +C P + +C +G C P +CDG DC DE NC D+H Sbjct: 3374 -----KCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANC----------------DIH 3412 Query: 191 LVDPT-FFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ--TNAPSEE 247 + P+ F N+C G C+ D C E++C T AP++ Sbjct: 3413 VCLPSQFKCTNTNRCIPGIFRCNGQDNC-------------GDGEDERDCPEVTCAPNQF 3459 Query: 248 EYLSGQ--------ADHMHSC-------SAAGMYSCGT---KGSEIGVCIPMNATCNGIK 289 + + D + C + +CG + + G CIP C+G Sbjct: 3460 QCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGED 3519 Query: 290 ECPLGDDESKHCSECARKRCDHTCMNTPHGARC 322 +C G DE K EC + C+ P+ RC Sbjct: 3520 DCGDGSDEPKE--ECDERTCE------PYQFRC 3544
Score = 72.8 bits (177), Expect = 2e-11 Identities = 75/290 (25%), Positives = 128/290 (44%), Gaps = 23/290 (7%) Query: 343 CATHGHLCQHFCEDR-LGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 CA CQ C R G AC CA+G L DG SC+ A GYL S ++ + Sbjct: 2160 CAVANGGCQQLCLYRGGGQRACACAHGM-LAEDGASCREYA-----GYLLYSERTILKSI 2213 Query: 402 PLADFTDGSNYSAIQKFAGHGTIRSI---DFMHRN-------NKMFMSISDEHGDPTGEL 451 L+D + + + +Q F ++++ F +R N++F SD H ++ Sbjct: 2214 HLSD--ERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFF--SDIHFGNIQQI 2269 Query: 452 SVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISI-CTMSGMFCRRVIEG 510 + +G ++ ENV V +A +++T + S ++ T G F R + Sbjct: 2270 NDDGSGRTTIV-ENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVIT 2328 Query: 511 KEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYI 570 R V+ + L+ W + + + IM A + G+ V L++ + P+ LAID+ Sbjct: 2329 MSGDDHPRAFVLDECQNLMFWTNWNELHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHR 2388 Query: 571 RHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADW 620 +YF D IER D R V++ + HP+ +A + ++W DW Sbjct: 2389 AEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDW 2438
Score = 65.9 bits (159), Expect = 3e-09 Identities = 50/150 (33%), Positives = 70/150 (46%), Gaps = 20/150 (13%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPA-EWQCDNVADCDKGRDESG-----CSYAHHC- 75 ++P TC EF C NG RC+ + +W+CD DC DE+ S H C Sbjct: 2850 ESPECEYPTCG-PNEFRCANG--RCLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCN 2906 Query: 76 STSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYN-ILKSRFDGSNPSAPTTFVGHNG 134 ++S LC +G CVA C+G+DDC DGSDE+ C N L + G + +G Sbjct: 2907 ASSQFLCSSGRCVAEALLCNGQDDCGDGSDERGCHVNECLSRKLSGCSQDCEDLKIGF-- 2964 Query: 135 PECHPPRLRCRSGQCIQPD-LVCDGHQDCS 163 + RCR G ++ D C +CS Sbjct: 2965 ------KCRCRPGFRLKDDGRTCADLDECS 2988
Score = 47.0 bits (110), Expect = 0.001 Identities = 40/153 (26%), Positives = 58/153 (37%), Gaps = 35/153 (22%) Query: 75 CSTSFMLCKNGL-CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHN 133 CS C++ + C++ ++CDGE DC DGSDE AP Sbjct: 28 CSPKQFACRDQITCISKGWRCDGERDCPDGSDE------------------APEICPQSK 69 Query: 134 GPECHPPRLRCRSGQ-CIQPDLVCDGHQDCSGGDDE--------VNCTRRGHENMQSSTD 184 C P C + C+ +C+G QDC G DE NC+R G ++ T Sbjct: 70 AQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTP 129 Query: 185 FHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVC 217 PT + N + ++ C D C Sbjct: 130 -------SGPTCYCNSSFQLQADGKTCKDFDEC 155
Score = 44.3 bits (103), Expect = 0.010 Identities = 59/171 (34%), Positives = 74/171 (43%), Gaps = 23/171 (13%) Query: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 M T L LLPL ++ T AP TC K+F C + ++ CI W+CD DC Sbjct: 1 MLTPPLLLLLPLLSALVSGATMDAP----KTC-SPKQFACRD-QITCISKGWRCDGERDC 54 Query: 61 DKGRDESG--C--SYAHHCSTSFMLC-KNGLCVANEFKCDGEDDCRDGSDE-QHC-EYNI 113 G DE+ C S A C + C LCV C+G DC DGSDE HC E Sbjct: 55 PDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRA 114 Query: 114 LKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPD-LVCDGHQDCS 163 SR + PT +GP C+ C S +Q D C +CS Sbjct: 115 NCSRMGCQHHCVPTP----SGPTCY-----CNSSFQLQADGKTCKDFDECS 156
Score = 40.0 bits (92), Expect = 0.17 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 4/105 (3%) Query: 519 GLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGD 578 G+ H I W+D I A D + ++ N + +A+D+I ++Y+ D Sbjct: 1927 GIDFHAENDTIYWVD--MGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTD 1984 Query: 579 VERQLIERVNIDTKERRVVISNGVHHPYDMAYF--NGFLYWADWG 621 +IE ++ R VVIS G+ P + G+L+W +WG Sbjct: 1985 QGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWG 2029
Score = 38.5 bits (88), Expect = 0.54 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 6/73 (8%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSY---AHHCSTSF 79 + P N C KEF C N RC+ + +C+ DC G DE CS C+T+ Sbjct: 3733 EPPTAQNPHCKDKKEFLCRNQ--RCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNA 3790 Query: 80 MLCKN-GLCVANE 91 +C + CV E Sbjct: 3791 SMCGDEARCVRTE 3803
>gi|15825005|gb|AAL09566.1|AF367720_1 lipoprotein receptor-related protein [Mus musculus] Length = 4545 Score = 239 bits (610), Expect = 1e-61 Identities = 196/706 (27%), Positives = 302/706 (42%), Gaps = 80/706 (11%) Query: 25 PAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKN 84 P V C F C +G RCIP W CD DC+ G DE+ C+ CS + C+N Sbjct: 2690 PGVKRPRC-PLNYFACPSG--RCIPMSWTCDKEDDCENGEDETHCN--KFCSEAQFECQN 2744 Query: 85 GLCVANEFKCDGEDDCRDGSDE-QHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLR 143 C++ ++ CDG DDC DGSDE HCE G C P Sbjct: 2745 HRCISKQWLCDGSDDCGDGSDEAAHCE-----------------------GKTCGPSSFS 2781 Query: 144 CRSGQ-CIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT-FFANED 201 C C+ +CDG +DC+ G DE + + +F L P F + D Sbjct: 2782 CPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHD 2841 Query: 202 NKCRSG--------YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTN---APSEEEYL 250 C G Y C + E +C + AP Sbjct: 2842 RDCADGSDESPECEYPTCGPNE--FRCANGRCLSSRQWECDGENDCHDHSDEAPKNPHCT 2899 Query: 251 SGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESK-HCSECARKR- 308 S + H C+A+ + C + G C+ CNG +C G DE H +EC ++ Sbjct: 2900 SPE----HKCNASSQFLCSS-----GRCVAEALLCNGQDDCGDGSDERGCHVNECLSRKL 2950 Query: 309 --CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCA 366 C C + G +C C+ G++L DDG TC D DEC+T C C + GS+ C C Sbjct: 2951 SGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECST-TFPCSQLCINTHGSYKCLCV 3009 Query: 367 NGYELE-TDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIR 425 GY D HSCK A T E +L + +R++ L DGSNY+ +++ G Sbjct: 3010 EGYAPRGGDPHSCK--AVTDEEPFLIFANRYYLRKLNL----DGSNYTLLKQ--GLNNAV 3061 Query: 426 SIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQ 485 ++DF +R ++ + G + ++ + + + R + +AVDW+GGN+++ Sbjct: 3062 ALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCD 3121 Query: 486 KSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMAN 545 K I + ++G + R + + R LVV G + W D + + I Sbjct: 3122 KGRDT---IEVSKLNGAY--RTVLVSSGLREPRALVVDVQNGYLYWTD-WGDHSLIGRIG 3175 Query: 546 MDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHP 605 MDGS I++D K+ P+ L +DY+ +Y+ D IE ++D R VV+S + H Sbjct: 3176 MDGSGRSIIVDTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHI 3235 Query: 606 YDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNP 665 + + F ++YW DW ++S+ T + +I T +R P + V H+L Q P++P Sbjct: 3236 FALTLFEDYVYWTDWETKSINRAHKTTGANKTLLISTLHR-PMDLHVFHALRQPDVPNHP 3294 Query: 666 CL--ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVT 709 C C LC++ P KC CP + +C+ T Sbjct: 3295 CKVNNGGCSNLCLLSPGGGH----KCACPTNFYLGGDGRTCVSNCT 3336
Score = 90.1 bits (222), Expect = 2e-16 Identities = 98/367 (26%), Positives = 126/367 (34%), Gaps = 92/367 (25%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC-DKGRDESGCSYAHHCSTSFMLCKNGLC 87 NS+C EF+C NG CI CD V+ C DK ++ + C +F C NG C Sbjct: 2522 NSSCRAQDEFECANG--ECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRC 2579 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 V+N C+G DDC DGSDE C N C RCR G Sbjct: 2580 VSNMLWCNGVDDCGDGSDEIPC-----------------------NKTACGVGEFRCRDG 2616 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLV------------DPT 195 CI C+ DC DE+NC+ S+ F V V P+ Sbjct: 2617 SCIGNSSRCNQFVDCEDASDEMNCSA-----TDCSSYFRLGVKGVLFQPCERTSLCYAPS 2671 Query: 196 FFANEDN-----------------KCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKN 238 + + N +C Y C SG CIP E + Sbjct: 2672 WVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGR-CIPMSWTCDKEDDCENGEDETH 2730 Query: 239 CQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES 298 C CS A + C CI C+G +C G DE+ Sbjct: 2731 CNK-----------------FCSEA-QFECQNHR-----CISKQWLCDGSDDCGDGSDEA 2767 Query: 299 KHCSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCED-EDECATHGHLCQHFCEDR 357 HC K C + + P C+ + L D C D DE T G L C+DR Sbjct: 2768 AHCEG---KTCGPSSFSCPGTHVCVPERW--LCDGDKDCTDGADESVTAGCLYNSTCDDR 2822 Query: 358 LGSFACK 364 F C+ Sbjct: 2823 --EFMCQ 2827
>gi|17224416|gb|AAL36970.1| LDLR dan [Mus musculus] Length = 1905 Score = 238 bits (608), Expect = 3e-61 Identities = 206/729 (28%), Positives = 306/729 (41%), Gaps = 99/729 (13%) Query: 43 GRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRD 102 G CIPA+WQCD DC DE GC+ CS C NG C+ + CDG++DC D Sbjct: 40 GECTCIPAQWQCDGDNDCGDHSDEDGCTLP-TCSPLDFHCDNGKCIRRSWVCDGDNDCED 98 Query: 103 GSDEQHCEYN-------------ILKSRF--DGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 SDEQ C ++S + DG N + + +C RC G Sbjct: 99 DSDEQDCPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDG 158 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRR------GHENMQSS-----TDFHDDVHLVDPTF 196 CI CDG DC G DE +C E Q + D + D Sbjct: 159 SCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEFQCAYGRCILDIYHCDGDDDCGD 218 Query: 197 FANEDN-----KCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEY-- 249 +++E + CRSG MC SG +CI E+NC T+ + E++ Sbjct: 219 WSDESDCSSHQPCRSGEFMCDSG-LCINSGWRCDGDADCDDQSDERNCTTSMCTAEQFRC 277 Query: 250 -------LSGQADHMHSCS-AAGMYSCGTKGSEI----------GVCIPMNATCNGIKEC 291 LS + D C+ + +C GS G CI CNGI +C Sbjct: 278 RSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCASDQFLCWNGRCIGQRKLCNGINDC 337 Query: 292 PLGDDESKHCSECARKR------------CDHTCMNTPHGARCICQEGYKLADDGLTCED 339 DES + R R C C +C GY+L +DG TC+D Sbjct: 338 GDSSDESPQ--QNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTRHTGYRLTEDGRTCQD 395 Query: 340 EDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVR 399 +ECA G+ C C + G+F C C GYEL D SCK PE L + ++R Sbjct: 396 VNECAEEGY-CSQGCTNTEGAFQCWCEAGYELRPDRRSCK---ALGPEPVLLFANRIDIR 451 Query: 400 QMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLM 459 Q+ S Y+ + + ++DF HR +F SD D +++ + + Sbjct: 452 QV----LPHRSEYTLLLNNLENAI--ALDFHHRRELVFW--SDVTLDRILRANLNGSNVE 503 Query: 460 RVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRG 519 V+ + +AVDW+ +++T S ++ I + + G R + + + R Sbjct: 504 EVVSTGLESPGGLAVDWVHDKLYWTD---SGTSRIEVANLDG--AHRKVLLWQSLEKPRA 558 Query: 520 LVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDV 579 + +HPM G I W D + RI ++MDGS RI+ D L P+ L IDY +Y+ D Sbjct: 559 IALHPMEGTIYWTD-WGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDA 617 Query: 580 ERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQV 639 + +IER N+D R+ VIS G+ HP+ + F LYW DW ++S+ + ++ Sbjct: 618 KHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSAN-KFTGKNQEI 676 Query: 640 IHTFNRYPYGIAVNHSLYQTGPPS--NPCLELE--CPWLCVIVPKSDFIMTAKCVCPDGY 695 I +P I H+L+ P+ N C + C LC +P C CP G+ Sbjct: 677 IRNKLHFPMDI---HTLHPQRQPAGKNRCGDNNGGCTHLC--LPSGQ---NYTCACPTGF 728 Query: 696 THSVTENSC 704 + ++C Sbjct: 729 -RKINSHAC 736
Score = 110 bits (276), Expect = 7e-23 Identities = 90/354 (25%), Positives = 164/354 (46%), Gaps = 24/354 (6%) Query: 341 DECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQ 400 ++C + C H C R SF+C C G +L+ D +C +PE YL S G +R+ Sbjct: 1311 NKCGSRNGGCSHLCLPRPSSFSCACPTGIQLKGDRKTCD----PSPETYLLFSSRGSIRR 1366 Query: 401 MPLADFTDGSNYSAIQ-KFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLM 459 + L D +++ + G + S+D+ + K++ +D D ++ + + Sbjct: 1367 ISL----DTDDHTDVHVPVPGLNNVISLDYDSVHGKVYY--TDVFLDVIRRADLNGSNME 1420 Query: 460 RVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRG 519 V+ + +AVDW+ N+++T + I + G CR+V+ + R Sbjct: 1421 TVIGHGLKTTDGLAVDWVARNLYWTDTGRNT---IEASRLDGS-CRKVLINNSLDEP-RA 1475 Query: 520 LVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDV 579 + V P +G + W D + +I AN+DGS+ ++L++ L P+ L +DY +Y+ D Sbjct: 1476 IAVFPRKGYLFWTD-WGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDA 1534 Query: 580 ERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQV 639 IE +++ K R+V++S+ V HP+ + + ++YW DW ++S++ + + V Sbjct: 1535 HLDRIESADLNGKLRQVLVSH-VSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETV 1593 Query: 640 IHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPD 693 + I V QTG + C LC SDF+ C CPD Sbjct: 1594 LANVEGL-MDIIVVSPQRQTGTNACGVNNGGCTHLC-FARASDFV----CACPD 1641
Score = 87.0 bits (214), Expect = 1e-15 Identities = 87/377 (23%), Positives = 161/377 (42%), Gaps = 40/377 (10%) Query: 340 EDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVR 399 ++ C + C H C ++ C C G+ + + H+C + + +L + ++R Sbjct: 699 KNRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHAC----AQSLDKFLLFARRMDIR 753 Query: 400 QMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFM------SISDEHGDPTGELSV 453 ++ D D S+ + A + ++D+ R++ ++ +IS D TG+ V Sbjct: 754 RISF-DTEDLSD--DVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVV 810 Query: 454 SDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQ 513 D L E+ G +A+DW+ +++T + + I + G R + E Sbjct: 811 VDTSL-----ESPAG---LAIDWVTNKLYWTD---AGTDRIEVANTDGSM--RTVLIWEN 857 Query: 514 GQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHD 573 R +VV PM G + W D + +I A MD S ++++ + L P+ LAIDY Sbjct: 858 LDRPRDIVVEPMGGYMYWTD-WGASPKIERAGMDASSRQVIISSNLTWPNGLAIDYGSQR 916 Query: 574 VYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHH 633 +Y+ D + IE +D +R+V+I + + HP+ + + +YW DW ++S++ + Sbjct: 917 LYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTG 976 Query: 634 HSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE---CPWLCVIVPK-SDFIMTAKC 689 T + H ++ PP +E C LC+ P S F C Sbjct: 977 LDR----ETLQENLENLMDIHVFHRQRPPVTTLCAVENGGCSHLCLRSPNPSGF----SC 1028 Query: 690 VCPDGYTHSVTENSCIP 706 CP G +C P Sbjct: 1029 TCPTGINLLRDGKTCSP 1045
Score = 71.6 bits (174), Expect = 6e-11 Identities = 91/383 (23%), Positives = 157/383 (40%), Gaps = 57/383 (14%) Query: 343 CATHGHLCQHFC--EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQ 400 CA C H C F+C C G L DG +C + +L + +VR Sbjct: 1006 CAVENGGCSHLCLRSPNPSGFSCTCPTGINLLRDGKTC----SPGMNSFLIFARRIDVRM 1061 Query: 401 MPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDP-TGELSVSDNGLM 459 + L I FA + I+ M N + + + DP G++ SD+ L Sbjct: 1062 VSL----------DIPYFA--DVVVPIN-MTMKNTIAIGV-----DPLEGKVYWSDSTLH 1103 Query: 460 RVLRENVIG-------------VSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRR 506 R+ R ++ G +AVD IG V++T + + I + + G R+ Sbjct: 1104 RISRASLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTD---TGTNRIEVGNLDGSM-RK 1159 Query: 507 VIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALA 566 V+ + S R +V++ G + W D + + ++ + MDGS +L++N L P+ L Sbjct: 1160 VLVWQNL-DSPRAIVLYHEMGFMYWTD-WGENAKLERSGMDGSDRTVLINNNLGWPNGLT 1217 Query: 567 IDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLK 626 +D + + D + IE +++ R ++S V HPY + + ++YW DW + S+ Sbjct: 1218 VDKTSSQLLWADAHTERIEVADLNGANRHTLVSP-VQHPYGLTLLDSYIYWTDWQTRSIH 1276 Query: 627 VQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPS-NPCLELE--CPWLCVIVPKSDF 683 + + + VI + P G+ ++ + P N C C LC+ P S Sbjct: 1277 RADKS---TGSNVILVRSNLP-GLMDIQAVDRAQPLGFNKCGSRNGGCSHLCLPRPSS-- 1330 Query: 684 IMTAKCVCPDGYTHSVTENSCIP 706 C CP G +C P Sbjct: 1331 ---FSCACPTGIQLKGDRKTCDP 1350
>gi|6678720|ref|NP_032538.1| low density lipoprotein receptor-related protein 1; low density lipoprotein receptor related protein; low density lipoprotein receptor related protein 1 [Mus musculus] gi|109553|pir||S25111 alpha-2-macroglobulin receptor precursor - mouse gi|49942|emb|CAA47817.1| AM2 receptor [Mus musculus] Length = 4545 Score = 236 bits (602), Expect = 1e-60 Identities = 195/706 (27%), Positives = 301/706 (42%), Gaps = 80/706 (11%) Query: 25 PAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKN 84 P V C F C +G RCIP W CD DC+ G DE+ C+ CS + C+N Sbjct: 2690 PGVKRPRC-PLNYFACPSG--RCIPMSWTCDKEDDCENGEDETHCN--KFCSEAQFECQN 2744 Query: 85 GLCVANEFKCDGEDDCRDGSDE-QHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLR 143 C++ ++ CDG DDC DGSDE HCE G C P Sbjct: 2745 HRCISKQWLCDGSDDCGDGSDEAAHCE-----------------------GKTCGPSSFS 2781 Query: 144 CRSGQ-CIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT-FFANED 201 C C+ +CDG +DC+ G DE + + +F L P F + D Sbjct: 2782 CPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHD 2841 Query: 202 NKCRSG--------YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTN---APSEEEYL 250 C G Y C + E +C + AP Sbjct: 2842 RDCADGSDESPECEYPTCGPNE--FRCANGRCLSSRQWECDGENDCHDHSDEAPKNPHCT 2899 Query: 251 SGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESK-HCSECARKR- 308 S + H C+A+ + C + G C+ CNG +C G DE H +EC ++ Sbjct: 2900 SPE----HKCNASSQFLCSS-----GRCVAEALLCNGQDDCGDGSDERGCHVNECLSRKL 2950 Query: 309 --CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCA 366 C C + G +C C+ G++L DDG TC D DEC+T C C + GS+ C C Sbjct: 2951 SGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECST-TFPCSQLCINTHGSYKCLCV 3009 Query: 367 NGYELE-TDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIR 425 GY D HSCK A T E +L + +R++ L DGSNY+ +++ G Sbjct: 3010 EGYAPRGGDPHSCK--AVTDEEPFLIFANRYYLRKLNL----DGSNYTLLKQ--GLNNAV 3061 Query: 426 SIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQ 485 ++ F +R ++ + G + ++ + + + R + +AVDW+GGN+++ Sbjct: 3062 ALAFDYREQMIYWTGVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCD 3121 Query: 486 KSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMAN 545 K I + ++G + R + + R LVV G + W D + + I Sbjct: 3122 KGRDT---IEVSKLNGAY--RTVLVSSGLREPRALVVDVQNGYLYWTD-WGDHSLIGRIG 3175 Query: 546 MDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHP 605 MDGS I++D K+ P+ L +DY+ +Y+ D IE ++D R VV+S + H Sbjct: 3176 MDGSGRSIIVDTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHI 3235 Query: 606 YDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNP 665 + + F ++YW DW ++S+ T + +I T +R P + V H+L Q P++P Sbjct: 3236 FALTLFEDYVYWTDWETKSINRAHKTTGANKTLLISTLHR-PMDLHVFHALRQPDVPNHP 3294 Query: 666 CL--ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVT 709 C C LC++ P KC CP + +C+ T Sbjct: 3295 CKVNNGGCSNLCLLSPGGGH----KCACPTNFYLGGDGRTCVSNCT 3336
Score = 178 bits (451), Expect = 3e-43 Identities = 175/681 (25%), Positives = 271/681 (39%), Gaps = 108/681 (15%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC +F C NG RCI W+CDN DC DE+GCS H CS++ C +G C+ Sbjct: 976 TCFPLTQFTCNNG--RCININWRCDNDNDCGDNSDEAGCS--HSCSSTQFKCNSGRCIPE 1031 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQC 149 + CDG++DC D SDE H +R G CH +C G C Sbjct: 1032 HWTCDGDNDCGDYSDETHANCTNQATRPPGG---------------CHSDEFQCPLDGLC 1076 Query: 150 IQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT--FFANEDNKCRSG 207 I CDG DC DE +C H+ DP F + +C S Sbjct: 1077 IPLRWRCDGDTDCMDSSDEKSC--------------EGVTHVCDPNVKFGCKDSARCISK 1122 Query: 208 YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYS 267 +C C E+NC+ A H C+ Sbjct: 1123 AWVCDGDSDC-------------EDNSDEENCEALACRPPS---------HPCA------ 1154 Query: 268 CGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKR--CDHTCMNTP-HGARCIC 324 + VC+P + C+G +C G DE + C +C+ C H C P G C C Sbjct: 1155 -----NNTSVCLPPDKLCDGKDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSC 1209 Query: 325 QEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATT 384 G +L D TC+ + CA H C C+ S C C G+ LE DG +C+ + Sbjct: 1210 PLGMELGSDNHTCQIQSYCAKHLK-CSQKCDQNKFSVKCSCYEGWVLEPDGETCR--SLD 1266 Query: 385 TPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEH 444 + ++ S E+R++ L +YS + G ++DF + ++ + + E Sbjct: 1267 PFKLFIIFSNRHEIRRIDLHK----GDYSVL--VPGLRNTIALDFHLSQSALYWTDAVED 1320 Query: 445 GDPTGELSVSDNGLMR----VLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMS 500 G+L DNG + V++ + +AVDWI GN+++ + + I + + Sbjct: 1321 KIYRGKL--LDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQ---IEVAKLD 1375 Query: 501 GMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLE 560 G ++ G + R + + P G++ W D RI A+M G+ R + Sbjct: 1376 GTLRTTLLAGDIEHP--RAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTIHRETGS 1433 Query: 561 --VPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNGFLY 616 + L +DY+ + + D I D V+ + HP+ + + G +Y Sbjct: 1434 GGCANGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVY 1493 Query: 617 WADWGSESL-KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCL----ELEC 671 W DW + +L K + T H+ + V+ N P+ + V H Q P NPC C Sbjct: 1494 WTDWRTNTLAKANKWTGHNVT--VVQRTNTQPFDLQVYHPSRQPMAP-NPCEANGGRGPC 1550 Query: 672 PWLCVIVPKSDFIMTAKCVCP 692 LC+I ++ T CP Sbjct: 1551 SHLCLI----NYNRTVSWACP 1567
Score = 152 bits (385), Expect = 2e-35 Identities = 183/784 (23%), Positives = 300/784 (38%), Gaps = 130/784 (16%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC + +F C N RC+P WQCD DC DE C+ CS S C NG C+A Sbjct: 3536 TC-EPYQFRCKNN--RCVPGRWQCDYDNDCGDNSDEESCT-PRPCSESEFFCANGRCIAG 3591 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCI 150 +KCDG+ DC DGSDE+ C P C + +C+SG CI Sbjct: 3592 RWKCDGDHDCADGSDEKDCT------------------------PRCDMDQFQCKSGHCI 3627 Query: 151 QPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTD-FHDDVHLVDP-TFFANEDNKCRSGY 208 CD DC G DE C G D F + L P + + ++ C Sbjct: 3628 PLRWPCDADADCMDGSDEEAC---GTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNS 3684 Query: 209 T-----------------MCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ------TNAPS 245 C + VC+ E++C+ + Sbjct: 3685 DENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTDEEDCEPPTAQNPHCKD 3744 Query: 246 EEEYLSGQADHMHSCSAAGMY-SCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSEC 304 ++E+L + S M+ CG E I T GD+ + C Sbjct: 3745 KKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASMCGDE-----ARC 3799 Query: 305 ARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACK 364 R T A C C+ G+ C+D +EC G C G C Sbjct: 3800 VR---------TEKAAYCACRSGFHTVPGQPGCQDINECLRFG-TCSQLWNKPKGGHLCS 3849 Query: 365 CANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTI 424 CA + ++T ++CK E + L+I+ E+R + F + + Q F G ++ Sbjct: 3850 CARNF-MKTH-NTCKAEGSEYQ--VLYIADDNEIRSL----FPGHPHSAYEQTFQGDESV 3901 Query: 425 R--SIDFMHRNNKMFM------SISDEHGDPTGELSVSDNGLMRVLRE----NVIGVS-- 470 R ++D + +++ +IS P + S+ ++ R N+ G+ Sbjct: 3902 RIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMP 3961 Query: 471 -NVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLI 529 +A+DW+ GNV++T S I + M G + +I G +VV P+RG + Sbjct: 3962 RGIAIDWVAGNVYWTD---SGRDVIEVAQMKGENRKTLISG--MIDEPHAIVVDPLRGTM 4016 Query: 530 IWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNI 589 W D + + +I A MDG+ L+ + ++ P+ LA+DY +Y+ D + +I + + Sbjct: 4017 YWSD-WGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRL 4075 Query: 590 DTKERRVVISN--GVHHPYDMAYFNGFLYWADW-GSESLKVQEMTHHHSSPQVIHTFNRY 646 + + V + G+ HP+ + F ++Y + + K+ + H SP T Sbjct: 4076 NGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGH---SPLYNLTGGLS 4132 Query: 647 PYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIP 706 V + ++ +NPC +C WLC++ P C CP+G + +C+P Sbjct: 4133 HASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSGPV-----CTCPNG--KRLDNGTCVP 4185 Query: 707 PVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDG 766 + + + + C NGG+C + C C+ Y G Sbjct: 4186 VPSPTPPPDAPRPG-----------TCTLQCFNGGSCFLNARRQPK-----CRCQPRYTG 4229 Query: 767 QYCE 770 CE Sbjct: 4230 DKCE 4233
Score = 142 bits (358), Expect = 2e-32 Identities = 107/369 (28%), Positives = 171/369 (46%), Gaps = 29/369 (7%) Query: 277 VCIPMNATCNGIKECPLGDDESKHCSE----CARKRCDHTCMNTPHGARCICQEGYKLAD 332 +C+PM+ CNGI++C G DE HC E C+R C H C+ TP G C C ++L Sbjct: 85 LCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLEA 144 Query: 333 DGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKY--EATTTPEGYL 390 DG TC+D DEC+ +G C C + GSF C C GY L+ D SCK E P L Sbjct: 145 DGKTCKDFDECSVYG-TCSQLCTNTDGSFTCGCVEGYLLQPDNRSCKAKNEPVDRPPVLL 203 Query: 391 FISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGE 450 + Q LA + G+ S I + T ++DF + N + + T Sbjct: 204 IAN-----SQNILATYLSGAQVSTITPTSTRQTT-AMDFSYANETVCWVHVGDSAAQTQL 257 Query: 451 LSVSDNGLMRVLRENVIGVS-------NVAVDWIGGNVFFTQKSPSPSAGISICTMSGMF 503 GL + E+ I +S +A+DW+ GN +F I +C +G Sbjct: 258 KCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDR---IFVCNRNGDT 314 Query: 504 CRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPS 563 C +++ + + +G+ + P G + + D Y + ++ +MDG L+D+K+ P Sbjct: 315 CVTLLD--LELYNPKGIALDPAMGKVFFTD-YGQIPKVERCDMDGQNRTKLVDSKIVFPH 371 Query: 564 ALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN-GVHHPYDMAYFNGFLYWADWGS 622 + +D + VY+ D IE V+ + K R+ +I + H Y + F +LY + S Sbjct: 372 GITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATN--S 429 Query: 623 ESLKVQEMT 631 ++ Q+ T Sbjct: 430 DNANTQQKT 438
Score = 86.7 bits (213), Expect = 2e-15 Identities = 97/367 (26%), Positives = 125/367 (34%), Gaps = 92/367 (25%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC-DKGRDESGCSYAHHCSTSFMLCKNGLC 87 NS+C EF+C NG CI CD V+ C DK ++ + C +F C NG C Sbjct: 2522 NSSCRAQDEFECANG--ECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRC 2579 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 V+N C+G D C DGSDE C N C RCR G Sbjct: 2580 VSNMLWCNGVDYCGDGSDEIPC-----------------------NKTACGVGEFRCRDG 2616 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLV------------DPT 195 CI C+ DC DE+NC+ S+ F V V P+ Sbjct: 2617 SCIGNSSRCNQFVDCEDASDEMNCSA-----TDCSSYFRLGVKGVLFQPCERTSLCYAPS 2671 Query: 196 FFANEDN-----------------KCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKN 238 + + N +C Y C SG CIP E + Sbjct: 2672 WVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGR-CIPMSWTCDKEDDCENGEDETH 2730 Query: 239 CQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES 298 C CS A + C CI C+G +C G DE+ Sbjct: 2731 CNK-----------------FCSEA-QFECQNHR-----CISKQWLCDGSDDCGDGSDEA 2767 Query: 299 KHCSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCED-EDECATHGHLCQHFCEDR 357 HC K C + + P C+ + L D C D DE T G L C+DR Sbjct: 2768 AHCEG---KTCGPSSFSCPGTHVCVPERW--LCDGDKDCTDGADESVTAGCLYNSTCDDR 2822 Query: 358 LGSFACK 364 F C+ Sbjct: 2823 --EFMCQ 2827
Score = 79.7 bits (195), Expect = 2e-13 Identities = 94/364 (25%), Positives = 157/364 (43%), Gaps = 35/364 (9%) Query: 350 CQHFC---EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADF 406 C H C +R S+A C + +L D +C YE + +L + E+R + L Sbjct: 1550 CSHLCLINYNRTVSWA--CPHLMKLHKDNTTC-YEF----KKFLLYARQMEIRGVDL--- 1599 Query: 407 TDGSNYSAIQKFA--GHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRE 464 D Y+ I F + +D+ R +++ SD ++ G+ V+ Sbjct: 1600 -DAPYYNYIISFTVPDIDNVTVLDYDAREQRVYW--SDVRTQAIKRAFINGTGVETVVSA 1656 Query: 465 NVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHP 524 ++ +AVDW+ N+F+T + I++ + G F V++G EQ GLVVHP Sbjct: 1657 DLPNAHGLAVDWVSRNLFWTSYDTNKKQ-INVARLDGSFKNAVVQGLEQPH---GLVVHP 1712 Query: 525 MRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLI 584 +RG + W D I MANMDGS +L + + P LAID+ +Y+ I Sbjct: 1713 LRGKLYWTDG----DNISMANMDGSNHTLLFSGQ-KGPVGLAIDFPESKLYWISSGNHTI 1767 Query: 585 ERVNIDTKERRVV--ISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHT 642 R N+D E V+ + + + +A L+WAD SE + S + ++ Sbjct: 1768 NRCNLDGSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSGSVVLRNS 1827 Query: 643 FNRYPYGIAVNHSLYQTGPPSNPCL--ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVT 700 + + S+ +NPC +C LC +P S+ T C+C GY+ Sbjct: 1828 TTLVMHMKVYDESIQLEHEGTNPCSVNNGDCSQLC--LPTSE--TTRSCMCTAGYSLRSG 1883 Query: 701 ENSC 704 + +C Sbjct: 1884 QQAC 1887
Score = 76.6 bits (187), Expect = 1e-12 Identities = 83/336 (24%), Positives = 123/336 (36%), Gaps = 91/336 (27%) Query: 11 PLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCS 70 P+ +H+ + + P V N C + C N L +C + G D C Sbjct: 3276 PMDLHVF--HALRQPDVPNHPC-KVNNGGCSNLCLLSPGGGHKCACPTNFYLGGDGRTC- 3331 Query: 71 YAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFV 130 +C+ S +CKN C+ +KCD EDDC D SDE P P Sbjct: 3332 -VSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEP---------------PDCPEF-- 3373 Query: 131 GHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVH 190 +C P + +C +G C P +CDG DC DE NC D+H Sbjct: 3374 -----KCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANC----------------DIH 3412 Query: 191 LVDPT-FFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ--TNAPSE- 246 + P+ F N+C G C+ D C E++C T AP++ Sbjct: 3413 VCLPSQFKCTNTNRCIPGIFRCNGQDNC-------------GDGEDERDCPEVTCAPNQF 3459 Query: 247 -----------------EEYLSGQADHMHSCSAAGMYSCGT---KGSEIGVCIPMNATCN 286 + + +D +C+ +CG + + G CIP C+ Sbjct: 3460 QCSITKRCIPRVWVCDRDNHCVDGSDEPANCT---QMTCGVDEFRCKDSGRCIPARWKCD 3516 Query: 287 GIKECPLGDDESKHCSECARKRCDHTCMNTPHGARC 322 G +C G DE K EC + C+ P+ RC Sbjct: 3517 GEDDCGDGSDEPKE--ECDERTCE------PYQFRC 3544
Score = 46.2 bits (108), Expect = 0.002 Identities = 40/153 (26%), Positives = 57/153 (37%), Gaps = 35/153 (22%) Query: 75 CSTSFMLCKNGL-CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHN 133 CS C++ + C++ ++CDGE DC DGSDE AP Sbjct: 28 CSPKQFACRDQITCISKGWRCDGERDCPDGSDE------------------APEICPQSK 69 Query: 134 GPECHPPRLRCRSGQ-CIQPDLVCDGHQDCSGGDDE--------VNCTRRGHENMQSSTD 184 C P C + C+ +C+G QDC G DE NC+R G ++ T Sbjct: 70 AQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTP 129 Query: 185 FHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVC 217 PT + N + + C D C Sbjct: 130 -------SGPTCYCNSSFQLEADGKTCKDFDEC 155
Score = 42.7 bits (99), Expect = 0.024 Identities = 57/171 (33%), Positives = 74/171 (43%), Gaps = 23/171 (13%) Query: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 M T L L+PL ++ T AP TC K+F C + ++ CI W+CD DC Sbjct: 1 MLTPPLLLLVPLLSALVSGATMDAP----KTC-SPKQFACRD-QITCISKGWRCDGERDC 54 Query: 61 DKGRDESG--C--SYAHHCSTSFMLC-KNGLCVANEFKCDGEDDCRDGSDE-QHC-EYNI 113 G DE+ C S A C + C LCV C+G DC DGSDE HC E Sbjct: 55 PDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRA 114 Query: 114 LKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPD-LVCDGHQDCS 163 SR + PT +GP C+ C S ++ D C +CS Sbjct: 115 NCSRMGCQHHCVPTP----SGPTCY-----CNSSFQLEADGKTCKDFDECS 156
Score = 40.0 bits (92), Expect = 0.16 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 4/105 (3%) Query: 519 GLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGD 578 G+ H I W+D I A D + ++ N + +A+D+I ++Y+ D Sbjct: 1927 GIDFHAENDTIYWVD--MGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTD 1984 Query: 579 VERQLIERVNIDTKERRVVISNGVHHPYDMAYF--NGFLYWADWG 621 +IE ++ R VVIS G+ P + G+L+W +WG Sbjct: 1985 QGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWG 2029
Score = 38.5 bits (88), Expect = 0.53 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 6/73 (8%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSY---AHHCSTSF 79 + P N C KEF C N RC+ + +C+ DC G DE CS C+T+ Sbjct: 3733 EPPTAQNPHCKDKKEFLCRNQ--RCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNA 3790 Query: 80 MLCKN-GLCVANE 91 +C + CV E Sbjct: 3791 SMCGDEARCVRTE 3803
Score = 34.7 bits (78), Expect = 6.9 Identities = 67/304 (22%), Positives = 95/304 (31%), Gaps = 76/304 (25%) Query: 104 SDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL--------------------R 143 +D CE + + G T GH C R+ Sbjct: 2473 NDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQEDFTCRAVNSSCRAQDEFE 2532 Query: 144 CRSGQCIQPDLVCDGHQDCSGGDDE--VNCTRRGHENMQSSTDFHDDVHLVDPTFFANED 201 C +G+CI L CDG C DE C R TF + Sbjct: 2533 CANGECISFSLTCDGVSHCKDKSDEKPSYCNSR----------------RCKKTFRQCNN 2576 Query: 202 NKCRSGYTMCHSGDVC------IPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQ-A 254 +C S C+ D C IP + +C N+ +++ + A Sbjct: 2577 GRCVSNMLWCNGVDYCGDGSDEIP--CNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDA 2634 Query: 255 DHMHSCSA---AGMYSCGTKG------SEIGVCIPMNATCNGIKECPLGDDESKHCSECA 305 +CSA + + G KG +C + C+G +C DE + C Sbjct: 2635 SDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDE-RDCPGVK 2693 Query: 306 RKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDEC-----ATHGHLCQHFCEDRLGS 360 R RC P G RCI TC+ ED+C TH C FC + Sbjct: 2694 RPRCPLNYFACPSG-RCIPMS--------WTCDKEDDCENGEDETH---CNKFCSE--AQ 2739 Query: 361 FACK 364 F C+ Sbjct: 2740 FECQ 2743
>gi|4758686|ref|NP_002323.1| low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) [Homo sapiens] gi|1708865|sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91) gi|88083|pir||S02392 alpha-2-macroglobulin receptor precursor - human gi|34339|emb|CAA32112.1| LDL-receptor related precursor (AA -19 to 4525) [Homo sapiens] gi|3493576|gb|AAC64265.1| lipoprotein receptor-related protein [Homo sapiens] Length = 4544 Score = 234 bits (597), Expect = 4e-60 Identities = 191/704 (27%), Positives = 302/704 (42%), Gaps = 76/704 (10%) Query: 25 PAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKN 84 P V C F C +G RCIP W CD DC+ G DE+ C+ CS + C+N Sbjct: 2689 PGVKRPRC-PLNYFACPSG--RCIPMSWTCDKEDDCEHGEDETHCN--KFCSEAQFECQN 2743 Query: 85 GLCVANEFKCDGEDDCRDGSDE-QHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLR 143 C++ ++ CDG DDC DGSDE HCE G C P Sbjct: 2744 HRCISKQWLCDGSDDCGDGSDEAAHCE-----------------------GKTCGPSSFS 2780 Query: 144 CRSGQ-CIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFH-DDVHLVDPTFFANED 201 C C+ +CDG +DC+ G DE + + +F + + F + D Sbjct: 2781 CPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHD 2840 Query: 202 NKCRSG--------YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTN-APSEEEYLSG 252 C G Y C + + + Q++ AP S Sbjct: 2841 RDCADGSDESPECEYPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSP 2900 Query: 253 QADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESK-HCSECARKR--- 308 + H C+A+ + C + G C+ CNG +C DE H +EC ++ Sbjct: 2901 E----HKCNASSQFLCSS-----GRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSG 2951 Query: 309 CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANG 368 C C + G +C C+ G++L DDG TC D DEC+T C C + GS+ C C G Sbjct: 2952 CSQDCEDLKIGFKCRCRPGFRLKDDGRTCADVDECST-TFPCSQRCINTHGSYKCLCVEG 3010 Query: 369 YELE-TDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSI 427 Y D HSCK A T E +L + +R++ L DGSNY+ +++ G ++ Sbjct: 3011 YAPRGGDPHSCK--AVTDEEPFLIFANRYYLRKLNL----DGSNYTLLKQ--GLNNAVAL 3062 Query: 428 DFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKS 487 DF +R ++ + G + ++ + + + R + +AVDW+GGN+++ K Sbjct: 3063 DFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKG 3122 Query: 488 PSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMD 547 I + ++G + R + + R LVV G + W D + + I MD Sbjct: 3123 RDT---IEVSKLNGAY--RTVLVSSGLREPRALVVDVQNGYLYWTD-WGDHSLIGRIGMD 3176 Query: 548 GSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYD 607 GS +++D K+ P+ L +DY+ +Y+ D IE ++D R VV+S + H + Sbjct: 3177 GSSRSVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFA 3236 Query: 608 MAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCL 667 + F ++YW DW ++S+ T + +I T +R P + V H+L Q P++PC Sbjct: 3237 LTLFEDYVYWTDWETKSINRAHKTTGTNKTLLISTLHR-PMDLHVFHALRQPDVPNHPCK 3295 Query: 668 --ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVT 709 C LC++ P KC CP + +C+ T Sbjct: 3296 VNNGGCSNLCLLSPGGGH----KCACPTNFYLGSDGRTCVSNCT 3335
Score = 191 bits (484), Expect = 6e-47 Identities = 180/681 (26%), Positives = 276/681 (40%), Gaps = 108/681 (15%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC +F C NG RCI W+CDN DC DE+GCS H CS++ C +G C+ Sbjct: 975 TCFPLTQFTCNNG--RCININWRCDNDNDCGDNSDEAGCS--HSCSSTQFKCNSGRCIPE 1030 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQC 149 + CDG++DC D SDE H +R G CH +CR G C Sbjct: 1031 HWTCDGDNDCGDYSDETHANCTNQATRPPGG---------------CHTDEFQCRLDGLC 1075 Query: 150 IQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT--FFANEDNKCRSG 207 I CDG DC DE +C H+ DP+ F + +C S Sbjct: 1076 IPLRWRCDGDTDCMDSSDEKSC--------------EGVTHVCDPSVKFGCKDSARCISK 1121 Query: 208 YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYS 267 +C + C E+NC++ A H C+ Sbjct: 1122 AWVCDGDNDC-------------EDNSDEENCESLACRPPS---------HPCA------ 1153 Query: 268 CGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKR--CDHTCMNTP-HGARCIC 324 + VC+P + C+G +C G DE + C +C+ C H C P G C C Sbjct: 1154 -----NNTSVCLPPDKLCDGNDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSC 1208 Query: 325 QEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATT 384 G +L D TC+ + CA H C C+ S C C G+ LE DG SC+ Sbjct: 1209 PLGMELGPDNHTCQIQSYCAKHLK-CSQKCDQNKFSVKCSCYEGWVLEPDGESCRSLDPF 1267 Query: 385 TPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEH 444 P ++ S E+R++ L +YS + G ++DF + ++ + E Sbjct: 1268 KP--FIIFSNRHEIRRIDLHK----GDYSVL--VPGLRNTIALDFHLSQSALYWTDVVED 1319 Query: 445 GDPTGELSVSDNGLMR----VLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMS 500 G+L DNG + V++ + +AVDWI GN+++ + + I + + Sbjct: 1320 KIYRGKL--LDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQ---IEVAKLD 1374 Query: 501 GMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLE 560 G ++ G + R + + P G++ W D RI A+M G+ R + Sbjct: 1375 GTLRTTLLAGDIEHP--RAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGS 1432 Query: 561 --VPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNGFLY 616 P+ L +DY+ + + D I D V+ + HP+ + + G +Y Sbjct: 1433 GGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVY 1492 Query: 617 WADWGSESL-KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCL----ELEC 671 W DW + +L K + T H+ + V+ N P+ + V H Q P NPC + C Sbjct: 1493 WTDWRTNTLAKANKWTGHNVT--VVQRTNTQPFDLQVYHPSRQPMAP-NPCEANGGQGPC 1549 Query: 672 PWLCVIVPKSDFIMTAKCVCP 692 LC+I ++ T C CP Sbjct: 1550 SHLCLI----NYNRTVSCACP 1566
Score = 166 bits (420), Expect = 2e-39 Identities = 187/776 (24%), Positives = 301/776 (38%), Gaps = 114/776 (14%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC + +F C N RC+P WQCD DC DE C+ CS S C NG C+A Sbjct: 3535 TC-EPYQFRCKNN--RCVPGRWQCDYDNDCGDNSDEESCT-PRPCSESEFSCANGRCIAG 3590 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCI 150 +KCDG+ DC DGSDE+ C P C + +C+SG CI Sbjct: 3591 RWKCDGDHDCADGSDEKDCT------------------------PRCDMDQFQCKSGHCI 3626 Query: 151 QPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTD-FHDDVHLVDPTFF---ANEDNKCRS 206 CD DC G DE C G D F + L P + +D S Sbjct: 3627 PLRWRCDADADCMDGSDEEAC---GTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNS 3683 Query: 207 GYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC----QTNAPSEEEYLSGQADHMHSCSA 262 P + C ++EE H C Sbjct: 3684 DENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKD 3743 Query: 263 AGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCS------ECARKRC----DHT 312 + C + C+ + CN +C G DE + CS CA + Sbjct: 3744 KKEFLCRNQR-----CLSSSLRCNMFDDCGDGSDE-EDCSIDPKLTSCATNASICGDEAR 3797 Query: 313 CMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELE 372 C+ T A C C+ G+ C+D +EC G C C + G C CA + ++ Sbjct: 3798 CVRTEKAAYCACRSGFHTVPGQPGCQDINECLRFG-TCSQLCNNTKGGHLCSCARNF-MK 3855 Query: 373 TDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIR--SIDFM 430 T ++CK E + L+I+ E+R + F + + Q F G ++R ++D Sbjct: 3856 TH-NTCKAEGSEYQ--VLYIADDNEIRSL----FPGHPHSAYEQAFQGDESVRIDAMDVH 3908 Query: 431 HRNNKMFM------SISDEHGDPTGELSVSDNGLMRVLRE----NVIGVS---NVAVDWI 477 + +++ +IS P + S+ ++ R N+ G+ +A+DW+ Sbjct: 3909 VKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWV 3968 Query: 478 GGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQK 537 GNV++T S I + M G + +I G +VV P+RG + W D + Sbjct: 3969 AGNVYWTD---SGRDVIEVAQMKGENRKTLISG--MIDEPHAIVVDPLRGTMYWSD-WGN 4022 Query: 538 YHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVV 597 + +I A MDG+ L+ + ++ P+ LA+DY +Y+ D + +I + ++ + V Sbjct: 4023 HPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVA 4082 Query: 598 ISN--GVHHPYDMAYFNGFLYWADW-GSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNH 654 + G+ HP+ + F ++Y + + K+ + H SP V T V + Sbjct: 4083 ADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGH---SPLVNLTGGLSHASDVVLY 4139 Query: 655 SLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEE 714 ++ +NPC +C WLC++ P C CP+G + +C+P + Sbjct: 4140 HQHKQPEVTNPCDRKKCEWLCLLSPSGPV-----CTCPNG--KRLDNGTCVPVPSPTPPP 4192 Query: 715 NLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYDGQYCE 770 + + + C NGG+C + C C+ Y G CE Sbjct: 4193 DAPRPG-----------TCNLQCFNGGSCFLNARRQPK-----CRCQPRYTGDKCE 4232
Score = 136 bits (343), Expect = 1e-30 Identities = 102/354 (28%), Positives = 163/354 (46%), Gaps = 27/354 (7%) Query: 277 VCIPMNATCNGIKECPLGDDESKHCSE----CARKRCDHTCMNTPHGARCICQEGYKLAD 332 +C+PM+ CNG+++C G DE HC E C+R C H C+ T G C C ++L Sbjct: 84 LCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQA 143 Query: 333 DGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKY--EATTTPEGYL 390 DG TC+D DEC+ +G C C + GSF C C GY L+ D SCK E P L Sbjct: 144 DGKTCKDFDECSVYG-TCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKNEPVDRPPVLL 202 Query: 391 FISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGE 450 + Q LA + G+ S I + T ++DF + N + + T Sbjct: 203 IAN-----SQNILATYLSGAQVSTITPTSTRQTT-AMDFSYANETVCWVHVGDSAAQTQL 256 Query: 451 LSVSDNGLMRVLRENVIGVS-------NVAVDWIGGNVFFTQKSPSPSAGISICTMSGMF 503 GL + E+ I +S +A+DW+ GN +F I +C +G Sbjct: 257 KCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDR---IFVCNRNGDT 313 Query: 504 CRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPS 563 C +++ + + +G+ + P G + + D Y + ++ +MDG L+D+K+ P Sbjct: 314 CVTLLD--LELYNPKGIALDPAMGKVFFTD-YGQIPKVERCDMDGQNRTKLVDSKIVFPH 370 Query: 564 ALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN-GVHHPYDMAYFNGFLY 616 + +D + VY+ D IE V+ + K R+ +I + H Y + F +LY Sbjct: 371 GITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLY 424
Score = 89.0 bits (219), Expect = 3e-16 Identities = 80/302 (26%), Positives = 145/302 (48%), Gaps = 34/302 (11%) Query: 329 KLADDGLTCEDE--DECATHGHLCQHFC-EDRLGSFACKCANGYELETDGHSCKYEATTT 385 K+ D+ + + + + C+ + C C + +C C GY L + +C+ + Sbjct: 1834 KVYDESIQLDHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVGS-- 1891 Query: 386 PEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFM------S 439 +L S+ +R +PL D D S+ A+ +G IDF N+ ++ + Sbjct: 1892 ---FLLYSVHEGIRGIPL-DPNDKSD--ALVPVSGTSLAVGIDFHAENDTIYWVDMGLST 1945 Query: 440 ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTM 499 IS D T V NG+ R V +AVDWI GN+++T + I + + Sbjct: 1946 ISRAKRDQTWREDVVTNGIGR--------VEGIAVDWIAGNIYWTDQGFDV---IEVARL 1994 Query: 500 SGMFCRRVIEGKEQG-QSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNK 558 +G F VI QG R + VHP +G + W + + +Y RI + +DG++ +L++ Sbjct: 1995 NGSFRYVVI---SQGLDKPRAITVHPEKGYLFWTE-WGQYPRIERSRLDGTERVVLVNVS 2050 Query: 559 LEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKE-RRVVISNGVHHPYDMAYFNGFLYW 617 + P+ +++DY +Y+ D IER++++T E R VV+S+ + ++ F F+YW Sbjct: 2051 ISWPNGISVDYQDGKLYWCDARTDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYW 2110 Query: 618 AD 619 +D Sbjct: 2111 SD 2112
Score = 87.0 bits (214), Expect = 1e-15 Identities = 97/367 (26%), Positives = 124/367 (33%), Gaps = 92/367 (25%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC-DKGRDESGCSYAHHCSTSFMLCKNGLC 87 NS+C EF+C NG CI CD V C DK ++ + C +F C NG C Sbjct: 2521 NSSCRAQDEFECANG--ECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRC 2578 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 V+N C+G DDC DGSDE C N C RCR G Sbjct: 2579 VSNMLWCNGADDCGDGSDEIPC-----------------------NKTACGVGEFRCRDG 2615 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLV------------DPT 195 CI C+ DC DE+NC+ S+ F V V P+ Sbjct: 2616 TCIGNSSRCNQFVDCEDASDEMNCSA-----TDCSSYFRLGVKGVLFQPCERTSLCYAPS 2670 Query: 196 FFANEDN-----------------KCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKN 238 + + N +C Y C SG CIP E + Sbjct: 2671 WVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGR-CIPMSWTCDKEDDCEHGEDETH 2729 Query: 239 CQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES 298 C CS A + C CI C+G +C G DE+ Sbjct: 2730 CNK-----------------FCSEA-QFECQNHR-----CISKQWLCDGSDDCGDGSDEA 2766 Query: 299 KHCSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCED-EDECATHGHLCQHFCEDR 357 HC K C + + P C+ + L D C D DE G L C+DR Sbjct: 2767 AHCEG---KTCGPSSFSCPGTHVCVPERW--LCDGDKDCADGADESIAAGCLYNSTCDDR 2821 Query: 358 LGSFACK 364 F C+ Sbjct: 2822 --EFMCQ 2826
Score = 81.3 bits (199), Expect = 7e-14 Identities = 93/362 (25%), Positives = 155/362 (42%), Gaps = 31/362 (8%) Query: 350 CQHFCEDRLG-SFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTD 408 C H C + +C C + +L D +C YE + +L + E+R + L D Sbjct: 1549 CSHLCLINYNRTVSCACPHLMKLHKDNTTC-YEF----KKFLLYARQMEIRGVDL----D 1599 Query: 409 GSNYSAIQKFA--GHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENV 466 Y+ I F + +D+ R +++ SD ++ G+ V+ ++ Sbjct: 1600 APYYNYIISFTVPDIDNVTVLDYDAREQRVYW--SDVRTQAIKRAFINGTGVETVVSADL 1657 Query: 467 IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMR 526 +AVDW+ N+F+T + I++ + G F V++G EQ GLVVHP+R Sbjct: 1658 PNAHGLAVDWVSRNLFWTSYDTNKKQ-INVARLDGSFKNAVVQGLEQPH---GLVVHPLR 1713 Query: 527 GLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIER 586 G + W D I MANMDGS R LL + + P LAID+ +Y+ I R Sbjct: 1714 GKLYWTDG----DNISMANMDGSN-RTLLFSGQKGPVGLAIDFPESKLYWISSGNHTINR 1768 Query: 587 VNIDTKERRVV--ISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFN 644 N+D V+ + + + +A L+WAD SE + S + ++ Sbjct: 1769 CNLDGSGLEVIDAMRSQLGKATALAIMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTT 1828 Query: 645 RYPYGIAVNHSLYQTGPPSNPCL--ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTEN 702 + + S+ +NPC +C LC +P S+ T C+C GY+ + Sbjct: 1829 LVMHMKVYDESIQLDHKGTNPCSVNNGDCSQLC--LPTSE--TTRSCMCTAGYSLRSGQQ 1884 Query: 703 SC 704 +C Sbjct: 1885 AC 1886
Score = 78.6 bits (192), Expect = 4e-13 Identities = 68/274 (24%), Positives = 126/274 (45%), Gaps = 23/274 (8%) Query: 363 CKCANGYELETDGHSCKYEATTTPEGYLFISLG----GEVRQMPLADFTDGSNYSAIQKF 418 C+C +G+ L +DG SCK PE LF+ G G +R M + + I+ Sbjct: 504 CRCRSGFSLGSDGKSCK-----KPEHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENL 558 Query: 419 AGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIG 478 R++DF F+ +D G + +L++ + V VAVDW+G Sbjct: 559 MNP---RALDFHAETG--FIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWMG 613 Query: 479 GNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQ-- 536 N+++T P + ++ + + +IEGK R +VV P+ G + W D + Sbjct: 614 DNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKMTHP--RAIVVDPLNGWMYWTDWEEDP 671 Query: 537 ---KYHRIMMANMDGSQVRILLDNKLEV-PSALAIDYIRHDVYFGDVERQLIERVNIDTK 592 + R+ A MDGS I + +K + P+ L++D +Y+ D IE + ++ Sbjct: 672 KDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGT 731 Query: 593 ERRVVISN-GVHHPYDMAYFNGFLYWADWGSESL 625 +R++V ++H + + + +L+W ++ S S+ Sbjct: 732 DRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSV 765
Score = 75.9 bits (185), Expect = 3e-12 Identities = 77/291 (26%), Positives = 131/291 (45%), Gaps = 25/291 (8%) Query: 343 CATHGHLCQHFCEDR-LGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 CA CQ C R G AC CA+G L DG SC+ A GYL S ++ + Sbjct: 2159 CAVANGGCQQLCLYRGRGQRACACAHGM-LAEDGASCREYA-----GYLLYSERTILKSI 2212 Query: 402 PLADFTDGSNYSAIQKFAGHGTIRSI---DFMHRN-------NKMFMSISDEHGDPTGEL 451 L+D + + + +Q F ++++ F +R N++F SD H + Sbjct: 2213 HLSD--ERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFF--SDIHFGNIQQ- 2267 Query: 452 SVSDNGLMRV-LRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISI-CTMSGMFCRRVIE 509 ++D+G R+ + ENV V +A +++T + S ++ T G F R + Sbjct: 2268 -INDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVI 2326 Query: 510 GKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDY 569 R V+ + L+ W + +++ IM A + G+ V L++ + P+ LAID+ Sbjct: 2327 TMSGDDHPRAFVLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDH 2386 Query: 570 IRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADW 620 +YF D IER D R V++ + HP+ +A + ++W DW Sbjct: 2387 RAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDW 2437
Score = 75.5 bits (184), Expect = 3e-12 Identities = 83/333 (24%), Positives = 122/333 (36%), Gaps = 85/333 (25%) Query: 11 PLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCS 70 P+ +H+ + + P V N C + C N L +C + G D C Sbjct: 3275 PMDLHVF--HALRQPDVPNHPC-KVNNGGCSNLCLLSPGGGHKCACPTNFYLGSDGRTC- 3330 Query: 71 YAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFV 130 +C+ S +CKN C+ +KCD EDDC D SDE P P Sbjct: 3331 -VSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEP---------------PDCPEF-- 3372 Query: 131 GHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVH 190 +C P + +C +G C P +CDG DC DE NC D+H Sbjct: 3373 -----KCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANC----------------DIH 3411 Query: 191 LVDPT-FFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ--TNAPSEE 247 + P+ F N+C G C+ D C E++C T AP++ Sbjct: 3412 VCLPSQFKCTNTNRCIPGIFRCNGQDNC-------------GDGEDERDCPEVTCAPNQF 3458 Query: 248 EYLSGQ--------ADHMHSC-------SAAGMYSCGT---KGSEIGVCIPMNATCNGIK 289 + + D + C + +CG + + G CIP C+G Sbjct: 3459 QCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGED 3518 Query: 290 ECPLGDDESKHCSECARKRCDHTCMNTPHGARC 322 +C G DE K EC + C+ P+ RC Sbjct: 3519 DCGDGSDEPKE--ECDERTCE------PYQFRC 3543
Score = 63.9 bits (154), Expect = 1e-08 Identities = 49/150 (32%), Positives = 70/150 (46%), Gaps = 20/150 (13%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPA-EWQCDNVADCDKGRDESG-----CSYAHHC- 75 ++P TC + EF C NG RC+ + +W+CD DC DE+ S H C Sbjct: 2849 ESPECEYPTCGPS-EFRCANG--RCLSSRQWECDGENDCHDQSDEAPKNPHCTSPEHKCN 2905 Query: 76 STSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYN-ILKSRFDGSNPSAPTTFVGHNG 134 ++S LC +G CVA C+G+DDC D SDE+ C N L + G + +G Sbjct: 2906 ASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIGF-- 2963 Query: 135 PECHPPRLRCRSGQCIQPD-LVCDGHQDCS 163 + RCR G ++ D C +CS Sbjct: 2964 ------KCRCRPGFRLKDDGRTCADVDECS 2987
Score = 48.5 bits (114), Expect = 5e-04 Identities = 40/146 (27%), Positives = 56/146 (38%), Gaps = 21/146 (14%) Query: 75 CSTSFMLCKNGL-CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHN 133 CS C++ + C++ ++CDGE DC DGSDE AP Sbjct: 27 CSPKQFACRDQITCISKGWRCDGERDCPDGSDE------------------APEICPQSK 68 Query: 134 GPECHPPRLRCRSGQ-CIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLV 192 C P C + C+ +C+G QDC G DE R N H V + Sbjct: 69 AQRCQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTL 128 Query: 193 D-PTFFANEDNKCRSGYTMCHSGDVC 217 D PT + N + ++ C D C Sbjct: 129 DGPTCYCNSSFQLQADGKTCKDFDEC 154
Score = 40.0 bits (92), Expect = 0.16 Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 7/144 (4%) Query: 519 GLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGD 578 G+ H I W+D I A D + ++ N + +A+D+I ++Y+ D Sbjct: 1926 GIDFHAENDTIYWVD--MGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTD 1983 Query: 579 VERQLIERVNIDTKERRVVISNGVHHPYDMAYF--NGFLYWADWGSESLKVQEMTHHHSS 636 +IE ++ R VVIS G+ P + G+L+W +WG + Sbjct: 1984 QGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGTER 2043 Query: 637 PQVIHTFNRYPYGIAVNHSLYQTG 660 +++ +P GI+V+ YQ G Sbjct: 2044 VVLVNVSISWPNGISVD---YQDG 2064
Score = 38.1 bits (87), Expect = 0.70 Identities = 58/171 (33%), Positives = 73/171 (42%), Gaps = 24/171 (14%) Query: 1 MRTMRLAWLLPLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC 60 M T L LLPL ++ AP TC K+F C + ++ CI W+CD DC Sbjct: 1 MLTPPLLLLLPLLSALVAAAI-DAP----KTC-SPKQFACRD-QITCISKGWRCDGERDC 53 Query: 61 DKGRDESG--C--SYAHHCSTSFMLC-KNGLCVANEFKCDGEDDCRDGSDE-QHC-EYNI 113 G DE+ C S A C + C LCV C+G DC DGSDE HC E Sbjct: 54 PDGSDEAPEICPQSKAQRCQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQG 113 Query: 114 LKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPD-LVCDGHQDCS 163 SR + PT +GP C+ C S +Q D C +CS Sbjct: 114 NCSRLGCQHHCVPTL----DGPTCY-----CNSSFQLQADGKTCKDFDECS 155
Score = 37.0 bits (84), Expect = 1.3 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 6/73 (8%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSY---AHHCSTSF 79 + P + + C KEF C N RC+ + +C+ DC G DE CS C+T+ Sbjct: 3732 EPPTAHTTHCKDKKEFLCRNQ--RCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNA 3789 Query: 80 MLCKN-GLCVANE 91 +C + CV E Sbjct: 3790 SICGDEARCVRTE 3802
Score = 35.4 bits (80), Expect = 4.4 Identities = 67/302 (22%), Positives = 94/302 (31%), Gaps = 72/302 (23%) Query: 104 SDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL--------------------R 143 +D CE + + G T GH C R+ Sbjct: 2472 NDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQDDLTCRAVNSSCRAQDEFE 2531 Query: 144 CRSGQCIQPDLVCDGHQDCSGGDDE--VNCTRRGHENMQSSTDFHDDVHLVDPTFFANED 201 C +G+CI L CDG C DE C R TF + Sbjct: 2532 CANGECINFSLTCDGVPHCKDKSDEKPSYCNSR----------------RCKKTFRQCSN 2575 Query: 202 NKCRSGYTMCHSGDVC------IPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQ-A 254 +C S C+ D C IP + C N+ +++ + A Sbjct: 2576 GRCVSNMLWCNGADDCGDGSDEIP--CNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDA 2633 Query: 255 DHMHSCSA---AGMYSCGTKG------SEIGVCIPMNATCNGIKECPLGDDESKHCSECA 305 +CSA + + G KG +C + C+G +C DE + C Sbjct: 2634 SDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDE-RDCPGVK 2692 Query: 306 RKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGH---LCQHFCEDRLGSFA 362 R RC P G RCI TC+ ED+C HG C FC + F Sbjct: 2693 RPRCPLNYFACPSG-RCIPMS--------WTCDKEDDC-EHGEDETHCNKFCSE--AQFE 2740 Query: 363 CK 364 C+ Sbjct: 2741 CQ 2742
>gi|13562118|ref|NP_110454.1| low density lipoprotein receptor-related protein 2; glycoprotein 330; low density lipoprotein-related protein 2; megalin [Rattus norvegicus] gi|1708867|sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) gi|11275227|pir||T42737 gp330 protein precursor - rat gi|561853|gb|AAA51369.1| megalin Length = 4660 Score = 229 bits (585), Expect = 1e-58 Identities = 208/715 (29%), Positives = 306/715 (42%), Gaps = 117/715 (16%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCV 88 +STC + F C N CIP +W CD DC G DE C + C + C + C+ Sbjct: 1107 SSTC-PSTSFTCDNH--VCIPKDWVCDTDNDCSDGSDEKNCQASGTCQPTQFRCPDHRCI 1163 Query: 89 ANEFKCDGEDDCRDGSDEQHCEYNILKSRF---DGSN--------------------PSA 125 + + CDG+ DC DGSDE C N ++F DGS+ Sbjct: 1164 SPLYVCDGDKDCADGSDEAGCVLNCTSAQFKCADGSSCINSRYRCDGVYDCRDNSDEAGC 1223 Query: 126 PTTFVGHNGPECHPPRLRCR-SGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTD 184 PT G CHP +C+ G CI CDGH DC G DE H T Sbjct: 1224 PTRPPGM----CHPDEFQCQGDGTCIPNTWECDGHPDCIHGSDE-------HTGCVPKT- 1271 Query: 185 FHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQT--- 241 PT F ++ C +C + C EK+C T Sbjct: 1272 -------CSPTHFLCDNGNCIYKAWICDGDNDC-------------RDMSDEKDCPTQPF 1311 Query: 242 NAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHC 301 + PS + G + CI ++A C+G+ +CP G DES C Sbjct: 1312 HCPSTQWQCPGYS----------------------TCINLSALCDGVFDCPNGTDESPLC 1349 Query: 302 SE--CARKR--CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDR 357 ++ C+ C H CM P GA C+C GY+LA+D TCED +EC G QH C + Sbjct: 1350 NQDSCSHFNGGCTHQCMQGPFGATCLCPLGYQLANDTKTCEDINECDIPGFCSQH-CVNM 1408 Query: 358 LGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQK 417 GSF C C Y LE+DG +CK + P L ++ R + D ++ Sbjct: 1409 RGSFRCACDPEYTLESDGRTCKVTGSENP--LLVVA----SRDKIIVDNITAHTHNLYSL 1462 Query: 418 FAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGL-MRVLRENVIGVSN-VAVD 475 + ++DF ++F SD T SV NG RV+ ++ + V+ +AVD Sbjct: 1463 VQDVSFVVALDFDSVTGRVFW--SDLLQGKT--WSVFQNGTDKRVVHDSGLSVTEMIAVD 1518 Query: 476 WIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRG--LIIWID 533 WIG N+++T + I + + G R + + RGL + P G ++ W D Sbjct: 1519 WIGRNLYWTDYALET---IEVSKIDG--SHRTVLISKNVTKPRGLALDPRMGDNVMFWSD 1573 Query: 534 SYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKE 593 + + RI A+MDG+ +++ K+ P L+IDY +YF D IE + D Sbjct: 1574 -WGHHPRIERASMDGTMRTVIVQEKIYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGHN 1632 Query: 594 RRVVISNG--VHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIA 651 RR VI++ +HHP+ + F F+YW D G+ + H + V+++ ++ P GI Sbjct: 1633 RRQVIASDLVLHHPHALTLFEDFVYWTDRGTRQVMQANKWHGGNQSVVMYSVHQ-PLGIT 1691 Query: 652 VNHSLYQTGPPS-NPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCI 705 H Q PPS NPC C LC++ ++ C CP G+ S +C+ Sbjct: 1692 AIHPSRQ--PPSRNPCASASCSHLCLLSAQAP--RHYSCACPSGWNLSDDSVNCV 1742
Score = 212 bits (540), Expect = 2e-53 Identities = 186/693 (26%), Positives = 287/693 (41%), Gaps = 102/693 (14%) Query: 47 CIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDE 106 CIP+ W CD DC G DE CS M C NG C+ +E++CD DC DGSDE Sbjct: 80 CIPSSWVCDEDKDCSDGADEQQNCAGTTCSAQQMTCSNGQCIPSEYRCDHVSDCPDGSDE 139 Query: 107 QHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGD 166 ++C Y P C +L C +G C CD DC Sbjct: 140 RNCHY-----------------------PTCD--QLTCANGACYNTSQRCDQKVDCRDSS 174 Query: 167 DEVNCTRRGHENMQSSTDFH-DDVHLVDPTFFANEDNKCRS-------------GYTMCH 212 DE NCT + S +F + + + DN C G+ Sbjct: 175 DEANCT-----TLCSQKEFECGSGECILRAYVCDHDNDCEDNSDERNCNYDTCGGHQFTC 229 Query: 213 SGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKG 272 S CI E C++N H C G+ Sbjct: 230 SNGQCINQNWVCDGDDDCQDSGDEDGCESNQSH------------HRCYPREWACPGS-- 275 Query: 273 SEIGVCIPMNATCNGIKECPLGDDESKHCSE-------CARKRCDHTCMNTPHGARCICQ 325 G CI ++ C+G+ +CP GDDE+ S C+ C++ C TP G C C Sbjct: 276 ---GRCISIDKVCDGVPDCPEGDDENNVTSGRTCGMGVCSVLNCEYQCHQTPFGGECFCP 332 Query: 326 EGYKL-ADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATT 384 G+ + ++D TC D D+C G +C CE+R G C C GY LE G CK + Sbjct: 333 PGHIINSNDSRTCIDFDDCQIWG-ICDQKCENRQGRHQCLCEEGYILER-GQHCKSSDSF 390 Query: 385 TPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEH 444 + +F R + + D G N+ + + G + +DF ++ +++F + Sbjct: 391 SAASVIF----SNGRDLLVGDL-HGRNFRILAESKNRGMVMGVDFHYQKHRVFWT----- 440 Query: 445 GDPTGE--LSVSDNGL--MRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMS 500 DP E S NGL +L +V N+AVDWI ++ + + I + + Sbjct: 441 -DPMQEKVFSTDINGLNTQEILNVSVDTPENLAVDWINNKLYLVETKVNR---IDVVNLE 496 Query: 501 GMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWID--SYQKYHRIMMANMDGSQVRILLDNK 558 G +RV E RG+ + P G + + D S ++ A MDGS + L+ K Sbjct: 497 GN--QRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKVERAFMDGSNRKDLVTTK 554 Query: 559 LEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNGFLY 616 + P+ + +D + VY+ D IE V D +R+ V G V HP+ ++ F ++ Sbjct: 555 VGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSLVPHPFGISLFEEHVF 614 Query: 617 WADWGSES-LKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE--CPW 673 + DW + +K + T ++PQV H + P+G+ V H+L Q +NPC C Sbjct: 615 FTDWTKMAVMKASKFT--ETNPQVYHQSSLRPHGVTVYHALRQPN-ATNPCGSNNGGCAQ 671 Query: 674 LCVIVPKSDF-IMTAKCVCPDGYTHSVTENSCI 705 +CV+ ++D + +C C G+ E+ C+ Sbjct: 672 VCVLSHRTDNGGLGYRCKCEFGFELDDDEHRCV 704
Score = 211 bits (537), Expect = 5e-53 Identities = 196/697 (28%), Positives = 294/697 (42%), Gaps = 93/697 (13%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDE-SGCSYA-HHCSTSFMLCKNGLCV 88 TC ++ EF C + + RCIP+ W CD ADC G DE C ++ + C S C NG C+ Sbjct: 2864 TC-RSNEFQCLSPQ-RCIPSYWFCDGEADCADGSDEPDTCGHSVNTCRASQFQCDNGRCI 2921 Query: 89 ANEFKCDGEDDCRDGSDE---QHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR 145 + + CDG++DC D SDE HCE S T F N PP R Sbjct: 2922 SGNWVCDGDNDCGDMSDEDQRHHCELQNCSS----------TQFTCVNS---RPPNRR-- 2966 Query: 146 SGQCIQPDLVCDGHQDCSGGDDEV-NCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKC 204 CI VCDG DCS DE+ NCT R + S + V +F + N C Sbjct: 2967 ---CIPQYWVCDGDADCSDALDELQNCTMRTCSAGEFSC---ANGRCVRQSFRCDRRNDC 3020 Query: 205 RS-------GYTMCHSGDV------CIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLS 251 Y CH+ CIP E N + E+E+L Sbjct: 3021 GDYSDERGCSYPPCHANQFTCQNGRCIP----------RFFVCDEDNDCGDGSDEQEHLC 3070 Query: 252 GQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES----KHCSECARK 307 + + C G CI M CN + +C DE C + + Sbjct: 3071 HTPE---PTCPLHQFRCDN-----GHCIEMGRVCNHVDDCSDNSDEKGCGINECLDSSIS 3122 Query: 308 RCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCAN 367 RCDH C +T C C GYKL D +C D DEC LC CE+ +GS+ CKCA Sbjct: 3123 RCDHNCTDTITSFYCSCLPGYKLMSDKRSCVDIDECKESPQLCSQKCENVVGSYICKCAP 3182 Query: 368 GYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSI 427 GY E DG SC+ + P YL S +R + TDGS+YS I G G + ++ Sbjct: 3183 GYIREPDGKSCRQNSNIEP--YLIFSNRYYIRNLT----TDGSSYSLI--LQGLGNVVAL 3234 Query: 428 DFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKS 487 DF +++ D + ++ ++ + ++AVDW+ +++ Sbjct: 3235 DFDRVEKRLYW--IDAEKQIIERMFLNKTNRETIINHRLRRAESLAVDWVSRKLYWLD-- 3290 Query: 488 PSPSAGISICTMSG----MFCRRVIEGKEQ--GQSYRGLVVHPMRGLIIWIDSYQKYHRI 541 + + + + G M + ++ + RG+V+HP RG + W D + + I Sbjct: 3291 -AILDCLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVYWAD-WGVHAYI 3348 Query: 542 MMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG 601 MDG+ +++ K+E P+A+ IDY +Y+ D IE +++ R V Sbjct: 3349 GRIGMDGTNKSVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGS 3408 Query: 602 VHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRY-PYGIAVNHSLYQTG 660 + HP+ + F ++W DW + + V++ + S +V+ + P+ I V H Y+ Sbjct: 3409 LPHPFALTIFEDTVFWTDWNTRT--VEKGNKYDGSGRVVLVNTTHKPFDIHVYHP-YRQP 3465 Query: 661 PPSNPCLELE--CPWLCVIVPKSDFIMTAKCVCPDGY 695 SNPC C LC+I C CPD + Sbjct: 3466 IMSNPCGTNNGGCSHLCLIKAGGRGF---TCACPDDF 3499
Score = 176 bits (447), Expect = 1e-42 Identities = 196/793 (24%), Positives = 310/793 (39%), Gaps = 154/793 (19%) Query: 32 CDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANE 91 C + +F C N CIP W+CD DC DE C CS S C + C+ + Sbjct: 3721 CHPSGDFRCANH--HCIPLRWKCDGTDDCGDNSDEENC-VPRECSESEFRCADQQCIPSR 3777 Query: 92 FKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQ 151 + CD E+DC D SDE+ CE CHP +C SG C+ Sbjct: 3778 WVCDQENDCGDNSDERDCEMKT-----------------------CHPEHFQCTSGHCVP 3814 Query: 152 PDLVCDGHQDCSGGDDEVNCTRR---------------GHENMQS---------STDFHD 187 L CDG DC DE C R H +QS D D Sbjct: 3815 KALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGENDCVDGSD 3874 Query: 188 -DVHLV------DPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ 240 ++HL P F ++++C G+ +C+ D C EK Sbjct: 3875 EEIHLCFNIPCESPQRFRCDNSRCVYGHQLCNGVDDC-------------GDGSDEKEEH 3921 Query: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 P+ H Y C G CI + C+ + +C DE+ Sbjct: 3922 CRKPT------------HKPCTDTEYKCSN-----GNCISQHYVCDNVNDCGDLSDETG- 3963 Query: 301 CS-----ECARKRCDHTCMNTPHGAR-CICQEGYKLA-DDGLTCEDEDECATHGHLCQHF 353 C+ CA C+ C G C C+ G+K + D +C+D +EC G +C Sbjct: 3964 CNLGDNRTCAENICEQNCTQLSSGGFICSCRPGFKPSTSDKNSCQDINECEEFG-ICPQS 4022 Query: 354 CEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYS 413 C + GS+ C C +G++ + + + A +P L + +R+ T +S Sbjct: 4023 CRNSKGSYECFCVDGFKSMSTHYGERCAADGSPP-LLLLPENVRIRKYN----TSSEKFS 4077 Query: 414 AIQKFAGHGTIRSIDFMHRNNKMFMSISD----EHGDPTGELSVS-----DNGLMRVLRE 464 + H I++ID+ + +S+ G G + + ++G +RE Sbjct: 4078 EYLEEEEH--IQTIDYDWDPEHIGLSVVYYTVLAQGSQFGAIKRAYIPNFESGSNNPIRE 4135 Query: 465 NVIGVS------NVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYR 518 +G+ +AVDW+G ++++ S + S I + T+ G + + +I Q Sbjct: 4136 VDLGLKYLMQPDGLAVDWVGRHIYW---SDAKSQRIEVATLDGRYRKWLI--TTQLDQPA 4190 Query: 519 GLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHD-VYFG 577 + V+P GL+ W D K +I A M+G +L+ L P+ L+IDY+ D VY+ Sbjct: 4191 AIAVNPKLGLMFWTDQ-GKQPKIESAWMNGEHRSVLVSENLGWPNGLSIDYLNDDRVYWS 4249 Query: 578 DVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSP 637 D + +IE + D +RR++I N P+ + F LYW + Q + Sbjct: 4250 DSKEDVIEAIKYDGTDRRLII-NEAMKPFSLDIFEDKLYWVAKEKGEVWRQNKFGKENKE 4308 Query: 638 QVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTH 697 +V+ N + + + H L SNPC ++ C LC++ P C CP G Sbjct: 4309 KVL-VVNPWLTQVRIFHQLRYNQSVSNPCKQV-CSHLCLLRPGG-----YSCACPQG--- 4358 Query: 698 SVTENSCIPPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIV 757 + + T++ + E M C CM+GG C +NE + Sbjct: 4359 ----SDFVTGSTVQCDAASEL-----PVTMPPPCR----CMHGGNCYFDENELPK----- 4400 Query: 758 CDCEGPYDGQYCE 770 C C Y G+YCE Sbjct: 4401 CKCSSGYSGEYCE 4413
Score = 89.7 bits (221), Expect = 2e-16 Identities = 95/335 (28%), Positives = 138/335 (41%), Gaps = 80/335 (23%) Query: 32 CDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDE--SGCSYAHHCSTSFMLCKNGLCVA 89 C+Q +F C NG CI +W+CDN DC G DE + C++ H C ++ C NG CV Sbjct: 2701 CNQL-QFTCLNG--HCINQDWKCDNDNDCGDGSDELPTVCAF-HTCRSTAFTCGNGRCVP 2756 Query: 90 NEFKCDGEDDCRDGSDEQHCEYNILKS--RFDGSNPSA-PTTFVGHNGPECH-------- 138 ++CD +DC D SDE C + S F SN P ++V + CH Sbjct: 2757 YHYRCDYYNDCGDNSDEAGCLFRNCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDEK 2816 Query: 139 -------PPRL-RCRSGQ-CIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDV 189 PP +C++ C+ +CDG DC G DE Sbjct: 2817 NCPPHTCPPDFTKCQTTNICVPRAFLCDGDNDCGDGSDE--------------------- 2855 Query: 190 HLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEY 249 +P + A+ + CRS C S CIP E +C S+E Sbjct: 2856 ---NPIYCAS--HTCRSNEFQCLSPQRCIP---------SYWFCDGEADCADG--SDEPD 2899 Query: 250 LSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKEC-PLGDDESKHCSECARKR 308 G + +++C A+ + C G CI N C+G +C + D++ +H C + Sbjct: 2900 TCGHS--VNTCRAS-QFQCDN-----GRCISGNWVCDGDNDCGDMSDEDQRH--HCELQN 2949 Query: 309 CDH---TCMNT-PHGARCICQEGYKLADDGLTCED 339 C TC+N+ P RCI Q Y + D C D Sbjct: 2950 CSSTQFTCVNSRPPNRRCIPQ--YWVCDGDADCSD 2982
Score = 77.8 bits (190), Expect = 6e-13 Identities = 82/345 (23%), Positives = 116/345 (33%), Gaps = 84/345 (24%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F CGN +CIP W+CD DC G DE C C++G C + + C+ Sbjct: 3518 QFLCGNNE-KCIPIWWKCDGQKDCSDGSDEPDLCPHRFCRLGQFQCRDGNCTSPQALCNA 3576 Query: 97 EDDCRDGSDE-------QHCEYNILKSRFDGSNPSA----PTTFVGHNGPE--------- 136 DC DGSDE CE N + P + N E Sbjct: 3577 RQDCADGSDEDRVLCEHHRCESNEWQCANKRCIPQSWQCDSVNDCLDNSDEDTSHCASRT 3636 Query: 137 CHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEV--NCTRRGHENMQSSTDFHDDVHLVDP 194 C P + +C +G+CI CD DC DE CT + N + T+F Sbjct: 3637 CRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIDECTTAAY-NCDNHTEF--------- 3686 Query: 195 TFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQA 254 C++ Y CIP E+ C++ Sbjct: 3687 --------SCKTNYR-------CIPQWAVCNGFDDCRDNSDEQGCESV------------ 3719 Query: 255 DHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES----KHCSECARKRCD 310 C +G + C CIP+ C+G +C DE + CSE + D Sbjct: 3720 ----PCHPSGDFRCANHH-----CIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRCAD 3770 Query: 311 HTCMNTPHGARCICQEGYKLADDG-------LTCEDEDECATHGH 348 C+ + R +C + D+ TC E T GH Sbjct: 3771 QQCIPS----RWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGH 3811
Score = 75.9 bits (185), Expect = 3e-12 Identities = 48/143 (33%), Positives = 65/143 (45%), Gaps = 29/143 (20%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSY----AHHCSTSFMLCKNGL 86 TC + F C +G C+P CD ADC DES C +C + CKN + Sbjct: 3799 TC-HPEHFQCTSG--HCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHV 3855 Query: 87 CVANEFKCDGEDDCRDGSDEQ-HCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR 145 C+ + + CDGE+DC DGSDE+ H +NI P P R RC Sbjct: 3856 CIQSFWICDGENDCVDGSDEEIHLCFNI---------------------PCESPQRFRCD 3894 Query: 146 SGQCIQPDLVCDGHQDCSGGDDE 168 + +C+ +C+G DC G DE Sbjct: 3895 NSRCVYGHQLCNGVDDCGDGSDE 3917
Score = 74.7 bits (182), Expect = 5e-12 Identities = 91/362 (25%), Positives = 149/362 (41%), Gaps = 33/362 (9%) Query: 339 DEDECATHGHLCQHFC--EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGG 396 + + C C HFC L + C CA G L DG SC T+ E +L SL Sbjct: 2343 NNNPCLQSNGGCSHFCFALPELPTPRCGCAFG-TLGNDGKSC----ATSQEDFLIYSLNN 2397 Query: 397 EVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMS--ISDEHGDPTGELSVS 454 +R + F + Q + GT ++D+ RNN++F + ++ G + S Sbjct: 2398 SLRSL---HFDPRDHSLPFQVISVAGTAIALDYDRRNNRIFFTQKLNSLRGQISYVSLYS 2454 Query: 455 DNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQG 514 + VL N+ +A DWI ++++ S +I +M+ R + + Sbjct: 2455 GSSSPTVLLSNIGVTDGIAFDWINRRIYYSDFSNQ-----TINSMAEDGSNRAVIARVSK 2509 Query: 515 QSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDV 574 R +V+ P RG + W D + +I A + G+ +++ L P+ LA+D + Sbjct: 2510 P--RAIVLDPCRGYMYWTD-WGTNAKIERATLGGNFRVPIVNTSLVWPNGLALDLETDLL 2566 Query: 575 YFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHH 634 Y+ D Q IER + R VV+S H + + + ++YW D + K+ + Sbjct: 2567 YWADASLQKIERSTLTGTNREVVVSTAF-HSFGLTVYGQYIYWTDLYTR--KIYRANKYD 2623 Query: 635 SSPQVIHT--FNRYPYGIAVNHSLYQTGPPSNPCLELE--CPWLCVIVPKSDFIMTAKCV 690 S V T P GI+ Q SNPC + C +C P A+C Sbjct: 2624 GSDLVAMTTRLPTQPSGISTVVKT-QRQQCSNPCDQFNGGCSHICAPGPNG-----AECQ 2677 Query: 691 CP 692 CP Sbjct: 2678 CP 2679
Score = 67.4 bits (163), Expect = 1e-09 Identities = 89/377 (23%), Positives = 152/377 (40%), Gaps = 45/377 (11%) Query: 350 CQHFC---EDRLGSFACKCANGYELETDGHSC-----KYEATTTPEGYLFISLGGEVRQM 401 C H C ++C C +G+ L D +C + + ISL EV+ Sbjct: 1710 CSHLCLLSAQAPRHYSCACPSGWNLSDDSVNCVRGDQPFLMSVRDNIIFGISLDPEVK-- 1767 Query: 402 PLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRV 461 SN + + G D +++ F+ + G+ + N + Sbjct: 1768 --------SNDAMVPI---SGIQHGYDVEFDDSEQFIYWVENPGEIHRVKTDGSNRTVFA 1816 Query: 462 LRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSG--MFCRRVI--EGKEQGQSY 517 + +A+DW+ N+++T + S I + T+ G + + +I +G G + Sbjct: 1817 PLSLLGSSLGLALDWVSRNIYYTTPA---SRSIEVLTLKGDTRYGKTLIANDGTPLGVGF 1873 Query: 518 R-GLVVHPMRGLIIWIDSYQKY---HRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHD 573 G+ V P RG + W D +I ANMDG+ ++IL L+ + +D Sbjct: 1874 PVGIAVDPARGKLYWSDHGTDSGVPAKIASANMDGTSLKILFTGNLQHLEVVTLDIQEQK 1933 Query: 574 VYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHH 633 +Y+ R +IER N+D ER +++ + + HP+ + + FLY++D E +V E Sbjct: 1934 LYWAVTSRGVIERGNVDGTERMILVHH-LAHPWGLVVYGSFLYYSD---EQYEVIERVDK 1989 Query: 634 HSSPQVIHTFNRYPY--GIAVNHSLYQTGPPSNPCLE--LECPWLCVIVPKSDFIMTAKC 689 S + + PY G+ V H SN C C +C+ VP F C Sbjct: 1990 SSGNNKVVLRDNVPYLRGLRVYHR-RNAADSSNGCSNNPNACQQICLPVPGGMF----SC 2044 Query: 690 VCPDGYTHSVTENSCIP 706 C G+ S SC P Sbjct: 2045 ACASGFKLSPDGRSCSP 2061
Score = 63.5 bits (153), Expect = 1e-08 Identities = 92/379 (24%), Positives = 161/379 (42%), Gaps = 44/379 (11%) Query: 338 EDEDECATHGHLCQHFCEDRLGS-FACKCANGYELETDGHSCKYEATTTPEGYLFISLGG 396 + + C+ + + CQ C G F+C CA+G++L DG SC + ++ +S+ Sbjct: 2018 DSSNGCSNNPNACQQICLPVPGGMFSCACASGFKLSPDGRSC-----SPYNSFMVVSMLP 2072 Query: 397 EVRQMPLADFTDGSNYSAIQKFAGHG-TIRSIDFMHRNNKMFMSISDEHGDPTGELSVSD 455 VR L + +D S A+ AG G + D N ++ D + + S Sbjct: 2073 AVRGFSL-ELSDHS--EAMVPVAGQGRNVLHADVDVANGFIYWC------DFSSSVR-SS 2122 Query: 456 NGLMRVLRE-----NVI-------GVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMF 503 NG+ R+ + NV+ G+ VA+DW GN++FT + I + ++ + Sbjct: 2123 NGIRRIKPDGSNFTNVVTYGIGANGIRGVALDWAAGNLYFTNAFVYETL-IEVLRINTTY 2181 Query: 504 CRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPS 563 RRV+ K R ++V P + W D QK +I + +D + +L+ + P Sbjct: 2182 -RRVLL-KVSVDMPRHIIVDPKHRYLFWADYGQK-PKIERSFLDCTNRTVLVSEGIVTPR 2238 Query: 564 ALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH-HPYDMAYFNGFLYWADWG- 621 LA+D+ +Y+ D LI R+++D E +VV + PY + F + W D Sbjct: 2239 GLAMDHDTGYIYWVDDSLDLIARIHLDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNL 2298 Query: 622 SESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPS----NPCLELE--CPWLC 675 + + + + P VI + + Q P+ NPCL+ C C Sbjct: 2299 KKVFQASKQPGNTDPPVVIRDKINLLRDVTIFDEHAQPLSPAELNNNPCLQSNGGCSHFC 2358 Query: 676 VIVPKSDFIMTAKCVCPDG 694 +P+ + T +C C G Sbjct: 2359 FALPE---LPTPRCGCAFG 2374
Score = 62.4 bits (150), Expect = 3e-08 Identities = 68/261 (26%), Positives = 91/261 (34%), Gaps = 63/261 (24%) Query: 76 STSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGP 135 ST F+ N C+ +KCDG+ DC DGSDE ++ RF Sbjct: 3516 STQFLCGNNEKCIPIWWKCDGQKDCSDGSDEP----DLCPHRF----------------- 3554 Query: 136 ECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDE--VNCTRRGHENMQ------------- 180 C + +CR G C P +C+ QDC+ G DE V C E+ + Sbjct: 3555 -CRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCESNEWQCANKRCIPQSW 3613 Query: 181 SSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXE--KN 238 +D + D CR G C++G CIP E Sbjct: 3614 QCDSVNDCLDNSDEDTSHCASRTCRPGQFKCNNGR-CIPQSWKCDVDNDCGDYSDEPIDE 3672 Query: 239 CQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDD-- 296 C T A ++C +SC T CIP A CNG +C D Sbjct: 3673 CTTAA--------------YNCDNHTEFSCKTNYR----CIPQWAVCNGFDDCRDNSDEQ 3714 Query: 297 --ESKHCSECARKRC-DHTCM 314 ES C RC +H C+ Sbjct: 3715 GCESVPCHPSGDFRCANHHCI 3735
Score = 61.6 bits (148), Expect = 6e-08 Identities = 64/262 (24%), Positives = 115/262 (43%), Gaps = 19/262 (7%) Query: 361 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG 420 + CKC G+EL+ D H C + +L S VR +P FT + + G Sbjct: 686 YRCKCEFGFELDDDEHRC-----VAVKNFLLFSSKTAVRGIP---FTLSTQEDVMVPVTG 737 Query: 421 HGT-IRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGG 479 + IDF +++ +F SD D + + G + + V + DWI Sbjct: 738 SPSFFVGIDFDAQHSTVFY--SDLSKDIIYKQKIDGTGKEVITANRLESVECLTFDWISR 795 Query: 480 NVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYH 539 N+++T +++ ++ R++I + R +VVHP G + D ++ Sbjct: 796 NLYWTDGGLK---SVTVLRLADKSRRQIISNL---NNPRSIVVHPTAGYMFLSDWFRP-A 848 Query: 540 RIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKER-RVVI 598 +IM A DGS + +++ L P+ LAID+ +Y+ D IE +D +R R+ Sbjct: 849 KIMRAWSDGSHLMPIVNTSLGWPNGLAIDWSASRLYWVDAFFDKIEHSTLDGLDRKRLGH 908 Query: 599 SNGVHHPYDMAYFNGFLYWADW 620 + + HP+ + F ++ DW Sbjct: 909 VDQMTHPFGLTVFKDNVFITDW 930
Score = 58.9 bits (141), Expect = 3e-07 Identities = 79/325 (24%), Positives = 102/325 (31%), Gaps = 101/325 (31%) Query: 53 QCDNVAD---------CDKGRDESGCSYAHH-------------------CSTSFMLCKN 84 QC N D C G + + C H C+ C N Sbjct: 2651 QCSNPCDQFNGGCSHICAPGPNGAECQCPHEGNWYLANDNKYCVVDTGTRCNQLQFTCLN 2710 Query: 85 GLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRC 144 G C+ ++KCD ++DC DGSDE PT H C C Sbjct: 2711 GHCINQDWKCDNDNDCGDGSDE------------------LPTVCAFHT---CRSTAFTC 2749 Query: 145 RSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKC 204 +G+C+ CD + DC DE C R N S+T+F C Sbjct: 2750 GNGRCVPYHYRCDYYNDCGDNSDEAGCLFR---NCNSTTEF-----------------TC 2789 Query: 205 RSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAG 264 +G CIP NC N S+E+ H+C Sbjct: 2790 SNGR--------CIPLSYVCNGI---------NNCHDNDTSDEKNCPP-----HTCPPD- 2826 Query: 265 MYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTPHGARCIC 324 TK +C+P C+G +C G DE+ CA C RCI Sbjct: 2827 ----FTKCQTTNICVPRAFLCDGDNDCGDGSDENP--IYCASHTCRSNEFQCLSPQRCI- 2879 Query: 325 QEGYKLADDGLTCED-EDECATHGH 348 Y D C D DE T GH Sbjct: 2880 -PSYWFCDGEADCADGSDEPDTCGH 2903
Score = 53.1 bits (126), Expect = 2e-05 Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 6/85 (7%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRD--ESGCSYAHH--CSTSFMLCKN 84 N C+ + F C N RC+ C+ V DC G D E C H C+ + C N Sbjct: 3882 NIPCESPQRFRCDNS--RCVYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSN 3939 Query: 85 GLCVANEFKCDGEDDCRDGSDEQHC 109 G C++ + CD +DC D SDE C Sbjct: 3940 GNCISQHYVCDNVNDCGDLSDETGC 3964
Score = 43.1 bits (100), Expect = 0.019 Identities = 55/225 (24%), Positives = 71/225 (31%), Gaps = 55/225 (24%) Query: 136 ECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT 195 +C C +G+C+ CDG DC DE C Sbjct: 1024 QCGSLSFPCNNGKCVPSFFRCDGVDDCHDNSDEHQC------------------------ 1059 Query: 196 FFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQAD 255 +N C C G CIP E+NC T+A S Sbjct: 1060 --GVFNNTCSPSAFACVRGGQCIPGQWHCDRQNDCLDGSDEQNCPTHATS---------- 1107 Query: 256 HMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMN 315 S + ++C VCIP + C+ +C G DE K+C A C T Sbjct: 1108 ---STCPSTSFTCDNH-----VCIPKDWVCDTDNDCSDGSDE-KNCQ--ASGTCQPTQFR 1156 Query: 316 TPHGARCICQ----EGYKLADDGLTCEDEDECATHGHLCQHFCED 356 P RCI +G K DG DE C + Q C D Sbjct: 1157 CPD-HRCISPLYVCDGDKDCADG---SDEAGCVLNCTSAQFKCAD 1197
>gi|21698928|dbj|BAC02725.1| vitellogenin receptor [Periplaneta americana] Length = 1709 Score = 226 bits (575), Expect = 1e-57 Identities = 186/687 (27%), Positives = 281/687 (40%), Gaps = 117/687 (17%) Query: 38 FDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGE 97 F C NG CI + CD +DC G DE C + C NG C + F CDG Sbjct: 28 FTCHNG--ECINDDKHCDGTSDCKDGSDEFDCDMVLCKEPHWFRCHNGRCTSKSFHCDGV 85 Query: 98 DDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCD 157 DDC SDE+ C Y + S P+ C RC CI D VCD Sbjct: 86 DDCGGWSDEEDC-YEM------ESKPA-----------NCTADEWRCVDNNCIFMDWVCD 127 Query: 158 GHQDCSGGDDEVN-CTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDV 216 G QDC G DE+ C+ + C G+ + Sbjct: 128 GKQDCMDGSDELQGCSHK---------------------------MSCEDGFVCGNYH-- 158 Query: 217 CIPXXXXXXXXXXXXXXXXEKNCQT--NAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSE 274 CIP EK C + N P E+ L ++ C + Sbjct: 159 CIPNSFLCDGFDDCGDNSDEKLCPSVRNVPPEDCKLE-----------KNLFLCADRQE- 206 Query: 275 IGVCIPMNATCNGIKECPLGDDESKHC----SECARKRCDHTCMNTPHGARCICQEGYKL 330 C+ + C+G C G DE C + C C H C+ +P G C+CQ GYK Sbjct: 207 ---CVEVRELCDGTPHCYDGSDEGPACNASRAACPTVGCSHQCIPSPQGPLCVCQVGYKT 263 Query: 331 ADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYL 390 D+ TC D DEC +G +C C + GS++C C GYE+ +D SCK T P+ + Sbjct: 264 VDNK-TCVDVDECMEYG-ICDQRCRNLQGSYSCYCDEGYEVGSDKRSCK---ATGPDALM 318 Query: 391 FISLGGEVRQMPL-ADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTG 449 S E+R + + DF Y Q R++ + N ++ + Sbjct: 319 LFSSTKEIRGLYVHKDFY----YVVAQSLE-----RAVGISYDGNHVYWT---------- 359 Query: 450 ELSVSDNGLMR----------VLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTM 499 EL + + ++R ++ V ++AVDWI GN++FT + I +C Sbjct: 360 ELMLGEEAIVRSKDDGSHIEAIVTAGVYQPEDLAVDWITGNIYFTDME---AQHIGVCVN 416 Query: 500 SGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKL 559 +G C ++ E R + + P+ GL+ W D + + I A MDGSQ + + L Sbjct: 417 NGSSCAVLV--NEDIDKPRAIALMPLEGLMFWSD-WGERPLIARAGMDGSQPEVFVSTDL 473 Query: 560 EVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWAD 619 P+ L IDY +Y+ D + +IE + +D +RRVV+ + V HPY +A F LYW+D Sbjct: 474 RFPNGLTIDYHNSRLYWVDAKLLVIESIKLDGSDRRVVLKDVVKHPYAIAVFEDTLYWSD 533 Query: 620 WGSESLKVQEMTHHHSSPQVIHTFNR--YPYGIAVNHSLYQTGPPSNPCLELECPWLCVI 677 W ++ +I ++ + YG+ + H +NPC C +C++ Sbjct: 534 WHGRDIQACNKFTGKDHRIIIREKSKGDFIYGVHIYHP-SMMKLVTNPCHNNWCSDICLL 592 Query: 678 VPKSDFIMTAKCVCPDGYTHSVTENSC 704 P + T C CP+ +++C Sbjct: 593 APNKTYTYT--CACPENKQLGADKHTC 617
Score = 201 bits (512), Expect = 3e-50 Identities = 190/699 (27%), Positives = 279/699 (39%), Gaps = 102/699 (14%) Query: 32 CDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANE 91 C++ +F C G CI W CD DC+ G DE C C S C G C+ E Sbjct: 919 CNEDLQFKCRTG--DCIVKSWYCDGSKDCEDGSDEENCEEV-TCEPSAFKCALGQCIPEE 975 Query: 92 FKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQ 151 + CDG+ DC D +DEQ+C AP P C P C +G+CI Sbjct: 976 WVCDGQSDCVDDTDEQNC---------------AP--------PTCGPGAFSCGNGRCID 1012 Query: 152 PDLVCDGHQDCSGGDDEVNCTRRGHENMQSST-------DFHDDVHLVDPTFFANEDNKC 204 L+C+ DC DE C + +E + + ++ H + T +C Sbjct: 1013 QTLLCNNVDDCGDRSDEDPCRKPANEEEERLSVILCKEGEYTCHPHGKNVTICLPSSGRC 1072 Query: 205 RSGYTMCHSGD-----------------VCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEE 247 +G C GD CIP E N + PS Sbjct: 1073 -NGTAECPLGDDERGCGCQDFQFTCYNGKCIPSEWVCDGINDCGDGSDENNARCQLPS-- 1129 Query: 248 EYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCS-EC-A 305 S C G CI ++ CN + C G DE C C A Sbjct: 1130 -------------SVGTPGPCTDYACNDGQCISLSLACNNKRNCEDGSDEGGQCDIACNA 1176 Query: 306 RKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKC 365 + CD C T +GY L+ DG C D DEC G C C + GSF+C C Sbjct: 1177 KSPCDQICQPTLAAQDATVHKGYVLSSDGAKCGDIDECEI-GGACAQVCHNTRGSFSCSC 1235 Query: 366 ANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLA-DFTDGSNYSAIQKFAGHGTI 424 G++L +D SCK A P ++F S G ++R++ FTD A K G Sbjct: 1236 HPGFQLRSDHVSCK--ALGEPMQFIF-SAGNQIRKVSHELRFTDVVYPEAELKVTG---- 1288 Query: 425 RSIDFMHRNNKMFMSISDEHGDPTGEL-SVSDNGLMRVLRENVIGVSNVAVDWIGGNVFF 483 +D +N+++ S D T + +S G + + ++AVDWI NV++ Sbjct: 1289 --LDVDSASNEVYWST-----DVTSTIYRLSLRGGEKAYATGIGTPGDIAVDWISRNVYY 1341 Query: 484 TQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSY-----QKY 538 KS +P A I C + C +V+ E G S + V P+ G I W + + Sbjct: 1342 VDKS-TPQA-IRACNLDEHRCAKVLV-IEHGFSVPKIAVDPIAGFIFWPEVTKWVFGEPS 1398 Query: 539 HRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI 598 + + + G ++ N L + + L +D +R +YF D ++ IE ++ + ++R +++ Sbjct: 1399 TDLFRSELTGRHKTMIETNNLMLVNGLTLDIVRQRIYFADQHKRTIECMDYNGEDRHIIV 1458 Query: 599 SN-GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLY 657 N V +P DMA F G LYW G+ L ++ H + I Y Y L Sbjct: 1459 HNEHVQNPIDMALFEGTLYWLTAGTGQLTSYKLYGPHE--RRIGKLQLYIYSSDQFTILQ 1516 Query: 658 QTGPPS--NPCLELECPWLCVIVPKSDFIMTAKCVCPDG 694 Q P+ NPC C LCV+ P T C+C G Sbjct: 1517 QAIQPAAVNPCANHSCSELCVMNPGG----TPSCLCSGG 1551
>gi|6806919|ref|NP_004516.1| low density lipoprotein-related protein 2; megalin [Homo sapiens] gi|6166537|sp|P98164|LRP2_HUMAN Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) gi|1809240|gb|AAB41649.1| gp330 precursor [Homo sapiens] Length = 4655 Score = 224 bits (571), Expect = 4e-57 Identities = 202/728 (27%), Positives = 308/728 (42%), Gaps = 101/728 (13%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSY--AHHCSTSFMLCKNGL 86 N+TC + F CG+G CIPA W+CD DC G DE C C + C N Sbjct: 1064 NNTCSSSA-FTCGHG--ECIPAHWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTCDNHQ 1120 Query: 87 CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRS 146 C++ + CD ++DC DGSDE++C ++ C P + C + Sbjct: 1121 CISKNWVCDTDNDCGDGSDEKNC----------------------NSTETCQPSQFNCPN 1158 Query: 147 GQCIQPDLVCDGHQDCSGGDDEVNCTRR--GHENMQSSTDFHDDVHLVDPTFFANEDNKC 204 +CI VCDG +DC G DEV C + +S D V F DN Sbjct: 1159 HRCIDLSFVCDGDKDCVDGSDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSD 1218 Query: 205 RSGYT-----MCHSGD-------VCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSG 252 +G MCHS + +CIP E N Y Sbjct: 1219 EAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEHNACVPKTCPSSYF-- 1276 Query: 253 QADHMHSCSAAGM----YSCGTKGSEI-------------------GVCIPMNATCNGIK 289 D+ + A + CG E +C+ ++ C+GI Sbjct: 1277 HCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIF 1336 Query: 290 ECPLGDDESKHC--SECA--RKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECAT 345 +CP G DES C + C+ C H C+ P GA+C+C G+ LA+D TCED DEC Sbjct: 1337 DCPNGTDESPLCNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDSKTCEDIDECDI 1396 Query: 346 HGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLAD 405 G QH C + GSF C C GY LE+DG +CK A+ + L ++ ++ +AD Sbjct: 1397 LGSCSQH-CYNMRGSFRCSCDTGYMLESDGRTCKVTASESL--LLLVASQNKI----IAD 1449 Query: 406 FTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMR--VLR 463 ++ I ++DF + ++F S + + S NG R V Sbjct: 1450 SVTSQVHNIYSLVENGSYIVAVDFDSISGRIFWSDATQ----GKTWSAFQNGTDRRVVFD 1505 Query: 464 ENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVH 523 ++I +A+DW+G N+++T + I + + G R + + + RGL + Sbjct: 1506 SSIILTETIAIDWVGRNLYWTDYALET---IEVSKIDG--SHRTVLISKNLTNPRGLALD 1560 Query: 524 PMRG--LIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVER 581 P L+ W D + + RI A+MDGS +++ +K+ P L IDY +YF D Sbjct: 1561 PRMNEHLLFWSD-WGHHPRIERASMDGSMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYL 1619 Query: 582 QLIERVNIDTKERRVVISNG--VHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQV 639 ++ + + RR VI++ + HPY + F +YW D + +V H Q Sbjct: 1620 DYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRATR--RVMRANKWHGGNQS 1677 Query: 640 IHTFN-RYPYGIAVNHSLYQTGPPS-NPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTH 697 + +N ++P GI H Q P S NPC C LC++ + + CVCP G++ Sbjct: 1678 VVMYNIQWPLGIVAVHPSKQ--PNSVNPCAFSRCSHLCLLSSQGPHFYS--CVCPSGWSL 1733 Query: 698 SVTENSCI 705 S +C+ Sbjct: 1734 SPDLLNCL 1741
Score = 203 bits (517), Expect = 9e-51 Identities = 200/700 (28%), Positives = 300/700 (42%), Gaps = 85/700 (12%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC Q F C +CIP+ W CD DCD G DE CS+ + C NG C+ + Sbjct: 66 TCQQGY-FKC-QSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPS 123 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCI 150 E++CD DC DG+DE C+Y P C +L C +G C Sbjct: 124 EYRCDHVRDCPDGADENDCQY-----------------------PTCE--QLTCDNGACY 158 Query: 151 QPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSG--- 207 CD DC DE+NCT N S + + + + DN C+ G Sbjct: 159 NTSQKCDWKVDCRDSSDEINCTEICLHNEFSC----GNGECIPRAYVCDHDNDCQDGSDE 214 Query: 208 ----YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAA 263 Y C P E +C+ N E+ SG D +H CS Sbjct: 215 HACNYPTCGGYQFTCP---SGRCIYQNWVCDGEDDCKDNG-DEDGCESGPHD-VHKCSPR 269 Query: 264 GMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-----KHCSE--CARKRCDHTCMNT 316 +SC E G CI + C+GI +CP +DE+ K+CS C+ C + C T Sbjct: 270 -EWSC----PESGRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLCSALNCQYQCHET 324 Query: 317 PHGARCICQEGYKLA-DDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDG 375 P+G C C GY + +D TC + D+C G +C CE R G C C GY LE G Sbjct: 325 PYGGACFCPPGYIINHNDSRTCVEFDDCQIWG-ICDQKCESRPGRHLCHCEEGYILER-G 382 Query: 376 HSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNK 435 CK + +F R + + D G ++ + + G + F + + Sbjct: 383 QYCKANDSFGEASIIF----SNGRDLLIGDI-HGRSFRILVESQNRGVAVGVAFHYHLQR 437 Query: 436 MFMSISDEHGDPTGELSVSDNGL--MRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAG 493 +F + + ++ SV NGL VL +V N+AVDW+ ++ + + Sbjct: 438 VFWTDTVQN----KVFSVDINGLNIQEVLNVSVETPENLAVDWVNNKIYLVETKVNR--- 490 Query: 494 ISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWID--SYQKYHRIMMANMDGSQV 551 I + + G + RV E RG+ V P G + + D S ++ A MDGS Sbjct: 491 IDMVNLDGSY--RVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNR 548 Query: 552 RILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMA 609 + L+ KL P+ + +D I VY+ D IE V D +R+ V+ G + HP+ ++ Sbjct: 549 KDLVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVS 608 Query: 610 YFNGFLYWADWGSES-LKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLE 668 F G +++ DW + LK + T ++PQV + + PYG+ V HSL Q +NPC + Sbjct: 609 LFEGQVFFTDWTKMAVLKANKFT--ETNPQVYYQASLRPYGVTVYHSLRQP-YATNPCKD 665 Query: 669 LE--CPWLCVIVPKSDFI-MTAKCVCPDGYTHSVTENSCI 705 C +CV+ ++D + +C C G+ E CI Sbjct: 666 NNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCI 705
Score = 201 bits (511), Expect = 4e-50 Identities = 184/743 (24%), Positives = 294/743 (39%), Gaps = 104/743 (13%) Query: 32 CDQAKEFDCGNGRLRCIPAEWQCDNVADC--DKGRDESGCSYAHHCSTSFMLCKNG-LCV 88 C+ EF C N RCIP E+ C+ V +C + DE C C + + C N +C+ Sbjct: 2780 CNATTEFMCNN--RRCIPREFICNGVDNCHDNNTSDEKNCP-DRTCQSGYTKCHNSNICI 2836 Query: 89 ANEFKCDGEDDCRDGSDEQ--HCEYNILKSR----------------------FDGSNPS 124 + CDG++DC D SDE +C + S FD S+ Sbjct: 2837 PRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDEP 2896 Query: 125 APTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSS-- 182 A GH+ C +C G+CI + +CDG DC DE + ++N S Sbjct: 2897 AS---CGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEF 2953 Query: 183 ---TDFHDDVHLVDPTFFANEDNKCRSGYT--------MCHSGD------VCIPXXXXXX 225 D D + ++ + D C GY C + +CIP Sbjct: 2954 LCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRTCSENEFTCGYGLCIPKIFRCD 3013 Query: 226 XXXXXXXXXXEKNCQTNAPSEEEYLSGQA---------DHMHSCSAAG---MYSCGTK-- 271 E+ C + ++ D + C M+ C T Sbjct: 3014 RHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEP 3073 Query: 272 -------GSEIGVCIPMNATCNGIKECPLGDDES----KHCSECARKRCDHTCMNTPHGA 320 + G CI M CN + +C DE C + + CDH C +T Sbjct: 3074 TCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGCGINECHDPSISGCDHNCTDTLTSF 3133 Query: 321 RCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKY 380 C C+ GYKL D TC D DEC +C CE+ +GS+ CKCA GY E DG +C+ Sbjct: 3134 YCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTCRQ 3193 Query: 381 EATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSI 440 + P YL S +R + + DG YS I G + ++DF +++ Sbjct: 3194 NSNIEP--YLIFSNRYYLRNLTI----DGYFYSLI--LEGLDNVVALDFDRVEKRLYW-- 3243 Query: 441 SDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMS 500 D + ++ ++ + ++AVDW+ +++ G+ + ++ Sbjct: 3244 IDTQRQVIERMFLNKTNKETIINHRLPAAESLAVDWVSRKLYWLDARLD---GLFVSDLN 3300 Query: 501 G----MFCRRVIEGKEQ--GQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRIL 554 G M + ++ + RGL +HP G + W D + + I MDG+ ++ Sbjct: 3301 GGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAY-IGRVGMDGTNKSVI 3359 Query: 555 LDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGF 614 + KLE P+ + IDY +Y+ D IE +++ R V + HP+ + F Sbjct: 3360 ISTKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDT 3419 Query: 615 LYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE--CP 672 +YW DW + +++ + +++T +R P+ I V H Y+ SNPC C Sbjct: 3420 IYWTDWNTRTVEKGNKYDGSNRQTLVNTTHR-PFDIHVYHP-YRQPIVSNPCGTNNGGCS 3477 Query: 673 WLCVIVPKSDFIMTAKCVCPDGY 695 LC+I P C CPD + Sbjct: 3478 HLCLIKPGGKGF---TCECPDDF 3497
Score = 162 bits (410), Expect = 2e-38 Identities = 189/797 (23%), Positives = 305/797 (38%), Gaps = 160/797 (20%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC +F C N CIP WQCD DC DE C+ C+ S C N C+ + Sbjct: 3718 TCHPVGDFRCKNH--HCIPLRWQCDGQNDCGDNSDEENCA-PRECTESEFRCVNQQCIPS 3774 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCI 150 + CD +DC D SDE+ CE CHP +C SG C+ Sbjct: 3775 RWICDHYNDCGDNSDERDCEMRT-----------------------CHPEYFQCTSGHCV 3811 Query: 151 QPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHD----------------------- 187 +L CDG DC DE +C R + + Sbjct: 3812 HSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGS 3871 Query: 188 --------DVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC 239 DV P F ++N+C + +C+ D C E++C Sbjct: 3872 DEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDC-----------GDGTDETEEHC 3920 Query: 240 QTNAPSE-EEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKEC-----PL 293 + P EY Y CG G CIP + C+ +C L Sbjct: 3921 RKPTPKPCTEY---------------EYKCGN-----GHCIPHDNVCDDADDCGDWSDEL 3960 Query: 294 GDDESKHCSECARKRCDHTCMNTPHGAR-CICQEGYKL-ADDGLTCEDEDECATHGHLCQ 351 G ++ K CA C+ C G C C G++ D +C D +EC G Q Sbjct: 3961 GCNKGKE-RTCAENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQ 4019 Query: 352 HFCEDRLGSFACKCANGYELETD--GHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDG 409 H C + GS+ C CA+G+ +D G C E ++ L + +R+ L+ Sbjct: 4020 H-CRNTKGSYECVCADGFTSMSDRPGKRCAAEGSSP---LLLLPDNVRIRKYNLSS-ERF 4074 Query: 410 SNYSAIQKFAGHGTIRSIDFMHRNNKMFMSI----SDEHGDPTGELSVS-----DNGLMR 460 S Y +++ I+++D+ + +S+ G G + + ++G Sbjct: 4075 SEYLQDEEY-----IQAVDYDWDPKDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNN 4129 Query: 461 VLRE------NVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQG 514 +++E V+ +AVDW+G ++++ S + I + + G + + +I Sbjct: 4130 LVQEVDLKLKYVMQPDGIAVDWVGRHIYW---SDVKNKRIEVAKLDGRYRKWLISTDLDQ 4186 Query: 515 QSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHD- 573 + + V+P GL+ W D + K +I A M+G IL+ L P+ L+IDY+ +D Sbjct: 4187 PA--AIAVNPKLGLMFWTD-WGKEPKIESAWMNGEDRNILVFEDLGWPTGLSIDYLNNDR 4243 Query: 574 VYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHH 633 +Y+ D + +IE + D +RRV+ + +PY + F LYW + Q Sbjct: 4244 IYWSDFKEDVIETIKYDGTDRRVIAKEAM-NPYSLDIFEDQLYWISKEKGEVWKQNKFGQ 4302 Query: 634 HSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPD 693 + + N + + + H L N C ++ C LC++ P C CP Sbjct: 4303 GKKEKTL-VVNPWLTQVRIFHQLRYNKSVPNLCKQI-CSHLCLLRPGG-----YSCACPQ 4355 Query: 694 GYTHSVTENSCIPPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRA 753 G +S I T E + +E ++ CM+GG C + + + Sbjct: 4356 G-------SSFIEGSTTECDAAIELPINLPPP---------CRCMHGGNCYFDETDLPK- 4398 Query: 754 HRIVCDCEGPYDGQYCE 770 C C Y G+YCE Sbjct: 4399 ----CKCPSGYTGKYCE 4411
Score = 103 bits (256), Expect = 1e-20 Identities = 97/344 (28%), Positives = 126/344 (36%), Gaps = 67/344 (19%) Query: 38 FDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHH-CSTSFMLCKNGLCVANEFKCDG 96 F C NG RC+P + CD V DC DE C ++ CS+S C +G C+ ++CD Sbjct: 1031 FPCKNG--RCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFTCGHGECIPAHWRCDK 1088 Query: 97 EDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVC 156 +DC DGSDE +C PT H C + C + QCI + VC Sbjct: 1089 RNDCVDGSDEHNC----------------PT----HAPASCLDTQYTCDNHQCISKNWVC 1128 Query: 157 DGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYT------- 209 D DC G DE NC E Q S + +D +F + D C G Sbjct: 1129 DTDNDCGDGSDEKNCNST--ETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLN 1186 Query: 210 ------MCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAA 263 C SGD CI E C T P Sbjct: 1187 CTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPP------------------- 1227 Query: 264 GM-YSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTPHGARC 322 GM +S + E G+CIP C+G +C G DE + C K C + + +G Sbjct: 1228 GMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEH---NACVPKTCPSSYFHCDNGN-- 1282 Query: 323 ICQEGYKLADDGLTC---EDEDECATHGHLCQHFCEDRLGSFAC 363 C L D C DE +C T C + LG C Sbjct: 1283 -CIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNIC 1325
Score = 96.7 bits (239), Expect = 2e-18 Identities = 100/395 (25%), Positives = 143/395 (36%), Gaps = 139/395 (35%) Query: 11 PLFIHILIKNTAQ-----------------APAVNNSTCD-------------------- 33 P I+ ++KN Q AP N + C Sbjct: 2637 PRGINTVVKNQKQQCNNPCEQFNGGCSHICAPGPNGAECQCPHEGNWYLANNRKHCIVDN 2696 Query: 34 ----QAKEFDCGNGRLRCIPAEWQCDNVADCDKGRD--ESGCSYAHHCSTSFMLCKNGLC 87 A F C NG RCI EW+CDN DC G D ES C+ H CS + C NG C Sbjct: 2697 GERCGASSFTCSNG--RCISEEWKCDNDNDCGDGSDEMESVCAL-HTCSPTAFTCANGRC 2753 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 V ++CD +DC DGSDE C + + +A T F+ C + Sbjct: 2754 VQYSYRCDYYNDCGDGSDEAGCLFR---------DCNATTEFM-------------CNNR 2791 Query: 148 QCIQPDLVCDGHQDCSGGD--DEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCR 205 +CI + +C+G +C + DE NC D C+ Sbjct: 2792 RCIPREFICNGVDNCHDNNTSDEKNCP----------------------------DRTCQ 2823 Query: 206 SGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGM 265 SGYT CH+ ++CIP + +C N+ Y + H+CS++ Sbjct: 2824 SGYTKCHNSNICIP---------RVYLCDGDNDCGDNSDENPTYCT-----THTCSSS-E 2868 Query: 266 YSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTP---HGARC 322 + C + G CIP + C+ +C DE C R TC+ G RC Sbjct: 2869 FQCAS-----GRCIPQHWYCDQETDCFDASDEPASCGHSER-----TCLADEFKCDGGRC 2918 Query: 323 ICQEGYKLADDGLTCEDEDECATHG-----HLCQH 352 I E C+ +++C H CQ+ Sbjct: 2919 IPSE--------WICDGDNDCGDMSDEDKRHQCQN 2945
Score = 72.8 bits (177), Expect = 2e-11 Identities = 96/390 (24%), Positives = 160/390 (41%), Gaps = 44/390 (11%) Query: 338 EDEDECATHGHLCQHFCEDRLGS-FACKCANGYELETDGHSCKYEATTTPEGYLFISLGG 396 E + C+ + + CQ C G F+C CA G++L D SC + ++ +S+ Sbjct: 2017 ESSNGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRSC-----SPYNSFIVVSMLS 2071 Query: 397 EVR--QMPLADFTD--------GSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGD 446 +R + L+D ++ G N + G I DF S S + Sbjct: 2072 AIRGFSLELSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDF---------SSSVASDN 2122 Query: 447 PTGELSVSDNGLMRVLRENV--IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFC 504 + + LM ++ + GV +AVDW+ GN++FT S + I + ++ + Sbjct: 2123 AIRRIKPDGSSLMNIVTHGIGENGVRGIAVDWVAGNLYFTNAFVSETL-IEVLRINTTY- 2180 Query: 505 RRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSA 564 RRV+ K R +VV P + W D Y + +I + +D + +L+ + P Sbjct: 2181 RRVLL-KVTVDMPRHIVVDPKNRYLFWAD-YGQRPKIERSFLDCTNRTVLVSEGIVTPRG 2238 Query: 565 LAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHH--PYDMAYFNGFLYWADWGS 622 LA+D VY+ D +I R+ I+ E VI G + PY + F + W D Sbjct: 2239 LAVDRSDGYVYWVDDSLDIIARIRIN-GENSEVIRYGSRYPTPYGITVFENSIIWVDRNL 2297 Query: 623 ESL-KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPS----NPCLELE--CPWLC 675 + + + + + P VI + + + Q P+ NPCLE C LC Sbjct: 2298 KKIFQASKEPENTEPPTVIRDNINWLRDVTIFDKQVQPRSPAEVNNNPCLENNGGCSHLC 2357 Query: 676 VIVPKSDFIMTAKCVCPDGYTHSVTENSCI 705 +P + T KC C G S +N I Sbjct: 2358 FALPG---LHTPKCDCAFGTLQSDGKNCAI 2384
Score = 72.4 bits (176), Expect = 3e-11 Identities = 75/287 (26%), Positives = 129/287 (44%), Gaps = 27/287 (9%) Query: 343 CATHGHLCQHFC-------EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLG 395 C + C+ C D LG F CKC G++L+TD C + +L S Sbjct: 663 CKDNNGGCEQVCVLSHRTDNDGLG-FRCKCTFGFQLDTDERHC-----IAVQNFLIFSSQ 716 Query: 396 GEVRQMPLADFTDGSNYSAIQKFAGHGT-IRSIDFMHRNNKMFMSISDEHGDPTGELSVS 454 +R +P FT + + +G+ + IDF +++ +F S +H + + Sbjct: 717 VAIRGIP---FTLSTQEDVMVPVSGNPSFFVGIDFDAQDSTIFFSDMSKH--MIFKQKID 771 Query: 455 DNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQG 514 G + V V ++A DWI N+++T S IS+ ++ R V+ + Sbjct: 772 GTGREILAANRVENVESLAFDWISKNLYWTD---SHYKSISVMRLADKTRRTVV---QYL 825 Query: 515 QSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDV 574 + R +VVHP G + + D ++ +IM A DGS + +++ L P+ LAID+ + Sbjct: 826 NNPRSVVVHPFAGYLFFTDWFRP-AKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRL 884 Query: 575 YFGDVERQLIERVNIDTKERRVVIS-NGVHHPYDMAYFNGFLYWADW 620 Y+ D IE D +RR + + HP+ +A F L++ DW Sbjct: 885 YWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDW 931
Score = 71.6 bits (174), Expect = 6e-11 Identities = 81/347 (23%), Positives = 115/347 (33%), Gaps = 81/347 (23%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F C N +CIP W+CD DC G DE C C +G C + + C+ Sbjct: 3516 QFLCANNE-KCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQCSDGNCTSPQTLCNA 3574 Query: 97 EDDCRDGSDE-------QHCEYNILK-------------SRFDGSNPSAPTTFVGHNGPE 136 +C DGSDE HC+ N + F+ ++ Sbjct: 3575 HQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCASRT 3634 Query: 137 CHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTF 196 C P + RC +G+CI CD DC DE E M S+ HL D Sbjct: 3635 CRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPI-----EECMSSA-------HLCDNF- 3681 Query: 197 FANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADH 256 + C++ Y CIP E+ C+ Sbjct: 3682 ---TEFSCKTNYR-------CIPKWAVCNGVDDCRDNSDEQGCEE--------------- 3716 Query: 257 MHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES----KHCSECARKRCDHT 312 +C G + C CIP+ C+G +C DE + C+E + + Sbjct: 3717 -RTCHPVGDFRCKNHH-----CIPLRWQCDGQNDCGDNSDEENCAPRECTESEFRCVNQQ 3770 Query: 313 CMNTPHGARCICQEGYKLADDG-------LTCEDEDECATHGHLCQH 352 C+ + R IC D+ TC E T GH C H Sbjct: 3771 CIPS----RWICDHYNDCGDNSDERDCEMRTCHPEYFQCTSGH-CVH 3812
Score = 68.9 bits (167), Expect = 3e-10 Identities = 80/362 (22%), Positives = 155/362 (42%), Gaps = 33/362 (9%) Query: 339 DEDECATHGHLCQHFCEDRLG--SFACKCANGYELETDGHSCKYEATTTPEGYLFISLGG 396 + + C + C H C G + C CA G L++DG +C + E +L +L Sbjct: 2342 NNNPCLENNGGCSHLCFALPGLHTPKCDCAFG-TLQSDGKNC----AISTENFLIFALSN 2396 Query: 397 EVRQMPLADFTDGSNYS-AIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSD 455 +R + L D N+S Q T+ S+D+ +++++ + + G + Sbjct: 2397 SLRSLHL----DPENHSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLS 2452 Query: 456 NGLM--RVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQ 513 +G+ V+ + +A DWI +++ S I +M+ R + + Sbjct: 2453 SGIHTPTVIASGIGTADGIAFDWITRRIYY-----SDYLNQMINSMAEDGSNRTVIARVP 2507 Query: 514 GQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHD 573 R +V+ P +G + W D + + +I A + G+ ++++ L +PS L +DY Sbjct: 2508 KP--RAIVLDPCQGYLYWAD-WDTHAKIERATLGGNFRVPIVNSSLVMPSGLTLDYEEDL 2564 Query: 574 VYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHH 633 +Y+ D Q IER + +R V+++ V H + + + ++YW D ++ ++ + Sbjct: 2565 LYWVDASLQRIERSTLTGVDREVIVNAAV-HAFGLTLYGQYIYWTDLYTQ--RIYRANKY 2621 Query: 634 HSSPQVIHTFNRYPYGIAVNHSLY-QTGPPSNPCLELE--CPWLCVIVPKSDFIMTAKCV 690 S Q+ T N +N + Q +NPC + C +C P A+C Sbjct: 2622 DGSGQIAMTTNLLSQPRGINTVVKNQKQQCNNPCEQFNGGCSHICAPGPNG-----AECQ 2676 Query: 691 CP 692 CP Sbjct: 2677 CP 2678
Score = 65.9 bits (159), Expect = 3e-09 Identities = 70/262 (26%), Positives = 93/262 (35%), Gaps = 65/262 (24%) Query: 76 STSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGP 135 ST F+ N C+ +KCDG+ DC DGSD E + RF Sbjct: 3514 STQFLCANNEKCIPIWWKCDGQKDCSDGSD----ELALCPQRF----------------- 3552 Query: 136 ECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGH----------------ENM 179 C + +C G C P +C+ HQ+C G DE H E+ Sbjct: 3553 -CRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESW 3611 Query: 180 QSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC 239 Q T F+D D CR G C +G CIP + +C Sbjct: 3612 QCDT-FNDCEDNSDEDSSHCASRTCRPGQFRCANGR-CIP---------QAWKCDVDNDC 3660 Query: 240 --QTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE 297 ++ P EE S H C +SC T CIP A CNG+ +C DE Sbjct: 3661 GDHSDEPIEECMSSA-----HLCDNFTEFSCKTNYR----CIPKWAVCNGVDDCRDNSDE 3711 Query: 298 S----KHCSECARKRC-DHTCM 314 + C RC +H C+ Sbjct: 3712 QGCEERTCHPVGDFRCKNHHCI 3733
Score = 38.5 bits (88), Expect = 0.42 Identities = 35/116 (30%), Positives = 46/116 (39%), Gaps = 31/116 (26%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQ-------------CDNVADCDKGRDESGCSYAHH 74 +N D + E DC RC +WQ CD + DC G DES + Sbjct: 1293 DNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDESPLCNGNS 1352 Query: 75 CST---------------SFMLCKNGLCVANEFK-CDGEDDCRD-GSDEQHCEYNI 113 CS + LC G +AN+ K C+ D+C GS QHC YN+ Sbjct: 1353 CSDFNGGCTHECVQEPFGAKCLCPLGFLLANDSKTCEDIDECDILGSCSQHC-YNM 1407
Score = 35.8 bits (81), Expect = 3.0 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 3/42 (7%) Query: 304 CARKRCDHTCM---NTPHGARCICQEGYKLADDGLTCEDEDE 342 CA RC H C+ PH C+C G+ L+ D L C +D+ Sbjct: 1704 CAFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNCLRDDQ 1745
>gi|1708864|sp|P98157|LRP1_CHICK Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) gi|1079416|pir||A53102 alpha-2-macroglobulin receptor precursor - chicken gi|438007|emb|CAA52870.1| alpha-2-macroglobulin receptor [Gallus gallus] Length = 4543 Score = 215 bits (548), Expect = 2e-54 Identities = 190/695 (27%), Positives = 295/695 (42%), Gaps = 74/695 (10%) Query: 35 AKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHH--CSTSFMLCKNGLCVANEF 92 A F C +G RCIP W CD DC+ G DE+ CS C C N C++ + Sbjct: 2692 ANYFACPSG--RCIPMTWTCDKEDDCENGEDETHCSERQDKFCYPVQFECNNHRCISKLW 2749 Query: 93 KCDGEDDCRDGSDE-QHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQ 151 CDG DDC DGSDE C + + P T+V C+ Sbjct: 2750 VCDGADDCGDGSDEDSRCRLTTCST----GSFQCPGTYV------------------CVP 2787 Query: 152 PDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMC 211 +CDG +DC+ G DE + N +F P F D+ G Sbjct: 2788 ERWLCDGDKDCADGADETLAAGCLYNNTCDEREFMCGNRQCIPKHFV-CDHDDDCGDGSD 2846 Query: 212 HSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQAD-HMHSCSAAGMYSCGT 270 S + P C +N+ E G+ D H HS A C + Sbjct: 2847 ESPECEYPTCGPHEFRCANG------RCLSNSQWE---CDGEFDCHDHSDEAPKNPRCSS 2897 Query: 271 KGSEI---------GVCIPMNATCNGIKECPLGDDE-SKHCSECARKR---CDHTCMNTP 317 S+ G CIP C+ +C G DE + +EC K+ C C + Sbjct: 2898 PESKCNDSFFMCKNGKCIPEALLCDNNNDCADGSDELNCFINECLNKKLSGCSQECEDLK 2957 Query: 318 HGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDG-H 376 G +C C+ G++L DDG TC D DEC+T + C C + LGS+ C C GY+L+ D Sbjct: 2958 IGYKCRCRPGFRLKDDGKTCIDIDECST-TYPCSQKCINTLGSYKCLCIEGYKLKPDNPT 3016 Query: 377 SCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKM 436 SCK A T E +L + +R++ L DGSNY+ +++ G ++DF +R + Sbjct: 3017 SCK--AVTDEEPFLIFANRYYLRKLNL----DGSNYTLLKQ--GLNNAVALDFDYREQMI 3068 Query: 437 FMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISI 496 + + G + ++ + + + R + +AVDW+GGN+++ K I + Sbjct: 3069 YWTDVTTQGSMIRRMHINGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDT---IEV 3125 Query: 497 CTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLD 556 ++G + R + + R LVV G + W D + + I MDG+ +++D Sbjct: 3126 SKLNGAY--RTVLVNSGLREPRALVVDVQNGYLYWTD-WGDHSLIGKIGMDGTNRSVIVD 3182 Query: 557 NKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLY 616 K+ P+ L +DYI +Y+ D IE ++D R V+S + H + + F ++Y Sbjct: 3183 TKITWPNGLTLDYINSRIYWADAREDYIEFASLDGSNRHTVLSQDIPHIFALTLFEDYIY 3242 Query: 617 WADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCL--ELECPWL 674 W DW ++S+ T + +I T +R P I + H Q P++PC C L Sbjct: 3243 WTDWETKSINRAHKTTGANKTLLISTLHR-PMDIHIYHPYRQPDVPNHPCKTNNAGCSNL 3301 Query: 675 CVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVT 709 C++ P KC CP + +C+ T Sbjct: 3302 CLLSPGGGH----KCACPTNFYLGSDGKTCVSNCT 3332
Score = 187 bits (474), Expect = 9e-46 Identities = 180/684 (26%), Positives = 275/684 (40%), Gaps = 114/684 (16%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC +F C NG RCI W+CDN DC DE+GCS H CS++ C +G C+ Sbjct: 973 TCFPLTQFTCNNG--RCININWRCDNDNDCGDNSDEAGCS--HSCSSNQFKCNSGRCIPV 1028 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQC 149 + CDG++DC D SDE H +R G CH +CR G C Sbjct: 1029 HWTCDGDNDCGDYSDETHANCTNQATRPPGG---------------CHTDEFQCRLDGLC 1073 Query: 150 IQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT--FFANEDNKCRSG 207 I CDG DC DE NC H+ DP F + +C S Sbjct: 1074 IPMRWRCDGDTDCMDSSDEKNC--------------EGVTHVCDPNVKFGCKDSARCISK 1119 Query: 208 YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQT---NAPSEEEYLSGQADHMHSCSAAG 264 +C C E+NC++ PS H+C+ Sbjct: 1120 AWVCDGDSDC-------------EDNSDEENCESLVCKPPS------------HTCA--- 1151 Query: 265 MYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKR--CDHTCMNTP-HGAR 321 + +C+P C+G +C G DE + C +C+ C H C P G Sbjct: 1152 --------NNTSICLPPEKLCDGSDDCGDGSDEGELCDQCSLNNGGCSHNCTVAPGEGIV 1203 Query: 322 CICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYE 381 C C G +L D TC+ + CA H C CE + C C G+ LE DG SC+ Sbjct: 1204 CSCPLGMELGADNKTCQIQSYCAKHLK-CSQKCEQDKYNVKCSCYEGWMLEPDGESCRSL 1262 Query: 382 ATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSIS 441 P ++ S E+R++ L +YS + G ++DF + ++ + Sbjct: 1263 DPFKP--FIIFSNRHEIRRIDLHR----GDYSVL--VPGLRNTIALDFHLNQSSLYWTDV 1314 Query: 442 DEHGDPTGELSVSDNGLMR----VLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISIC 497 E G+L +NG + V++ + +AVDWI GN+++ + + I + Sbjct: 1315 VEDKIYRGKL--LENGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQ---IEVA 1369 Query: 498 TMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDN 557 + G ++ G + R + + P G++ W D RI A+M G+ R + Sbjct: 1370 KLDGTMRTTLLAGDIEHP--RAIALDPRYGILFWTDWDASLPRIEAASMSGAGRRTIHKE 1427 Query: 558 KLE--VPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNG 613 P+ L +DY+ + + D I D V+ + HP+ + + G Sbjct: 1428 TGSGGWPNGLTVDYLEKRILWIDARSDAIYSALYDGTGHIEVLRGHEYLSHPFAVTLYGG 1487 Query: 614 FLYWADWGSESL-KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCL----E 668 +YW DW + +L K + T H+ + V+ N P+ + V H Q P NPC + Sbjct: 1488 EVYWTDWRTNTLAKANKWTGHNVT--VVQRTNTQPFDLQVYHPSRQPLAP-NPCEANGGK 1544 Query: 669 LECPWLCVIVPKSDFIMTAKCVCP 692 C LC+I ++ T C CP Sbjct: 1545 GPCSHLCLI----NYNRTLSCACP 1564
Score = 185 bits (469), Expect = 3e-45 Identities = 195/789 (24%), Positives = 309/789 (39%), Gaps = 138/789 (17%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC + +F C N RC+P WQCD DC DE C+ CS S C NG C+A Sbjct: 3532 TC-EPYQFRCKNN--RCVPGRWQCDYDNDCGDNSDEESCT-PRPCSESEFSCANGRCIAG 3587 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCI 150 +KCDG+ DC DGSDE+ C P C + +C++G CI Sbjct: 3588 RWKCDGDHDCADGSDEKDCI------------------------PRCEFDQYQCKNGHCI 3623 Query: 151 QPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTD-FHDDVHLVDPTFFA--NEDN----- 202 CD DC G DE +C G D F + L P + ED+ Sbjct: 3624 PMRWRCDADADCMDGTDEEDC---GTGVRTCPLDEFQCNNTLRKPLAWKCDGEDDCGDNS 3680 Query: 203 ----------KCRSGYTM-CHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLS 251 +C C + VC+ EK+C++ P+ + Sbjct: 3681 DENPEECLKFQCPPNRPFRCKNDRVCLWIGRQCDGIDNCGDNTDEKDCES--PTAKPKSC 3738 Query: 252 GQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRC-- 309 Q + C E CI N CN +C G DE E C Sbjct: 3739 SQDKNEFLC-------------ENKKCISANLRCNFFDDCGDGSDEKSCSHEHKSYDCMT 3785 Query: 310 -------DHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFA 362 + C+ C C+ G++ D +C+D +EC G C C + GS Sbjct: 3786 NTTMCGDEAQCIQAQSSTYCTCRRGFQKVPDKNSCQDVNECLRFG-TCSQLCNNTKGSHV 3844 Query: 363 CKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHG 422 C CA + ++TD + CK E + L+I+ ++R M F S Y + + Sbjct: 3845 CSCAKNF-MKTD-NMCKAEGSE--HQILYIADDNKIRSM--YPFNPNSAYEPAFQGDENV 3898 Query: 423 TIRSIDFMHRNNKMFMSISDEHGDPTGELSVS-------------------DNGLMRVLR 463 I ++D + NK++ ++ H TG +S D G+ + Sbjct: 3899 RIDAMDIYVKGNKIYW--TNWH---TGRISYCELPASSAASTASNRNRRQIDGGVTHLNI 3953 Query: 464 ENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVH 523 + +AVDW+ GN+++T S I + M G + +I G +VV Sbjct: 3954 SGLKMPRGIAVDWVAGNIYWTD---SGRDVIEVAQMKGENRKTLISG--MIDEPHAIVVD 4008 Query: 524 PMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQL 583 P+RG + W D + + +I A MDG+ L+ + ++ P+ LA+DY +Y+ D + + Sbjct: 4009 PLRGTMYWSD-WGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSV 4067 Query: 584 IERVNIDTKERRVVISN--GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIH 641 I + ++ + V I N G+ HP+ + F ++Y + + + H S + Sbjct: 4068 IGSIRLNGTDPVVAIDNKKGLSHPFSIDIFEDYIYGVTYINNRIFKIHKFGHKSVTNLTS 4127 Query: 642 TFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTE 701 N + + + H Y+ +NPC +C WLC++ P C CP+G Sbjct: 4128 GLN-HATDVVLYHQ-YKQPEVTNPCDRKKCEWLCLLSPSGPV-----CTCPNGKRLDNGT 4180 Query: 702 NSCIPPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCE 761 IP T SA++ + C+NGG+C N +A C C+ Sbjct: 4181 CVLIPSPT-------------ASAVVPTTDTCDLVCLNGGSC--FLNARKQAK---CRCQ 4222 Query: 762 GPYDGQYCE 770 Y+G+ C+ Sbjct: 4223 PRYNGERCQ 4231
Score = 122 bits (305), Expect = 3e-26 Identities = 97/355 (27%), Positives = 161/355 (45%), Gaps = 29/355 (8%) Query: 277 VCIPMNATCNGIKECPLGDDESKHCSE----CARKRCDHTCMNTPHGARCICQEGYKLAD 332 +CI M+ CNG+ +C G DE HC E C C H C+ T G C C ++LA+ Sbjct: 86 LCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALGCQHHCVPTLSGPACYCNNSFQLAE 145 Query: 333 DGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKY--EATTTPEGYL 390 D +C+D DEC +G C C + GS+ C C GY L+ D SCK E P L Sbjct: 146 DRRSCKDFDECTVYG-TCSQTCTNTEGSYTCSCVEGYLLQPDNRSCKAKNEPVDRPPVLL 204 Query: 391 FISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKM-FMSISDEHGDPTG 449 + Q LA + G+ I + T ++DF + + + ++ + D Sbjct: 205 IAN-----SQNILATYLSGAPVPNITPTSAKQTT-AMDFNYIEDTVCWVHVGDSASQTIL 258 Query: 450 ELSVSDNGLMRVLRENVIGVS-------NVAVDWIGGNVFFTQKSPSPSAGISICTMSGM 502 + + N L + E I +S +A+DW+ GN +F I +C +G+ Sbjct: 259 KCAKIPN-LKGFVEERSINISLSLHQVEQMAIDWLTGNFYFVDDIDDR---IFVCNKNGL 314 Query: 503 FCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVP 562 C +++ + + +G+ + P G + + D Y + ++ +MDG L+D+K+ P Sbjct: 315 TCVTLLD--LELYNPKGIALDPAMGKVFFTD-YGQIPKVERCDMDGQNRTKLVDSKIVFP 371 Query: 563 SALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN-GVHHPYDMAYFNGFLY 616 + +D + VY+ D IE V+ + K R +I + H Y + F +LY Sbjct: 372 HGITLDLVSRLVYWADAYLDYIEVVDYEGKNRHTIIQGILIEHLYGLTVFENYLY 426
Score = 97.1 bits (240), Expect = 1e-18 Identities = 86/284 (30%), Positives = 105/284 (36%), Gaps = 69/284 (24%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDE--SGCSYAHHCSTSFMLCKNGL 86 NSTC+ EF+CGNG CI CD V C DE S CS + C F+ C NG Sbjct: 2515 NSTCNVHDEFECGNG--DCIDFSRTCDGVVHCKDKSDEKQSYCS-SRKCKKGFLHCMNGR 2571 Query: 87 CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRS 146 CVA+ F C+G DDC D SDE C N C RCR Sbjct: 2572 CVASRFWCNGVDDCGDNSDEVPC-----------------------NKTSCAATEFRCRD 2608 Query: 147 GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHL-VDPTFFANEDNKCR 205 G CI C+ DC DE+NCT +TD L V T F Sbjct: 2609 GSCIGNSSRCNQFIDCEDASDEMNCT---------ATDCSSYFKLGVKGTTFQK------ 2653 Query: 206 SGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGM 265 C +C E+NC + A Sbjct: 2654 -----CEHTSLCYAPSWVCDGANDCGDYSDERNCPGGRKPK--------------CPANY 2694 Query: 266 YSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRC 309 ++C + G CIPM TC+ +C G+DE+ HCSE K C Sbjct: 2695 FACPS-----GRCIPMTWTCDKEDDCENGEDET-HCSERQDKFC 2732
Score = 93.6 bits (231), Expect = 1e-17 Identities = 81/300 (27%), Positives = 144/300 (48%), Gaps = 32/300 (10%) Query: 329 KLADDGLTCEDEDECATHGHLCQHFC-EDRLGSFACKCANGYELETDGHSCKYEATTTPE 387 K+ D+ + + C+ + C C S +C C GY L++ SC+ + Sbjct: 1832 KVYDESIQQAGSNPCSVNNGDCSQLCLPTSETSRSCMCTAGYSLKSGQQSCEGVGS---- 1887 Query: 388 GYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFM------SIS 441 +L S+ +R +PL D D S+ A+ +G IDF N+ ++ +IS Sbjct: 1888 -FLLYSVHEGIRGIPL-DPNDKSD--ALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTIS 1943 Query: 442 DEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSG 501 D T V NG+ R V +AVDWI GN+++T + I + ++G Sbjct: 1944 RAKRDQTWREDVVTNGIGR--------VEGIAVDWIAGNIYWTDQGFDV---IEVARLNG 1992 Query: 502 MFCRRVIEGKEQG-QSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLE 560 F VI QG R + VHP +G + W + + +Y RI + +DG++ +L++ + Sbjct: 1993 SFRYVVI---SQGLDKPRAITVHPEKGYLFWTE-WGQYPRIERSRLDGTERMVLVNVSIS 2048 Query: 561 VPSALAIDYIRHDVYFGDVERQLIERVNIDTKE-RRVVISNGVHHPYDMAYFNGFLYWAD 619 P+ +++DY +Y+ D IER++++T E R VV+S+ + ++ F ++YW+D Sbjct: 2049 WPNGISVDYEDGKLYWCDARTDKIERIDLETGENREVVLSSDNMDMFSVSVFEDYIYWSD 2108
Score = 85.5 bits (210), Expect = 4e-15 Identities = 71/277 (25%), Positives = 129/277 (46%), Gaps = 23/277 (8%) Query: 360 SFACKCANGYELETDGHSCKYEATTTPEGYLFISLG----GEVRQMPLADFTDGSNYSAI 415 S C+C +G+ L +DG SCK PE LF+ G G +R M + + I Sbjct: 503 SRTCRCRSGFSLGSDGKSCK-----KPEHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPI 557 Query: 416 QKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVD 475 + R++DF F+ +D G + +L++ + V +AVD Sbjct: 558 ENLMNP---RALDFHAETG--FIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGIAVD 612 Query: 476 WIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSY 535 W+G N+++T P + ++ + + +IEGK R +VV P+ G + W D Sbjct: 613 WMGNNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKMTHP--RAIVVDPLNGWMYWTDWE 670 Query: 536 Q-----KYHRIMMANMDGSQVRILLDNKLEV-PSALAIDYIRHDVYFGDVERQLIERVNI 589 + K +I A MDGS + + +K + P+ L++D +Y+ D IE V + Sbjct: 671 EDPKDSKRGKIERAWMDGSNRNVFITSKTVLWPNGLSLDIPAKILYWVDAFYDRIEMVYL 730 Query: 590 DTKERRVVISN-GVHHPYDMAYFNGFLYWADWGSESL 625 + ER++V ++H + + +++ FL+W ++ S S+ Sbjct: 731 NGTERKIVYEGPELNHAFGLCHYSSFLFWTEYRSGSI 767
Score = 79.0 bits (193), Expect = 3e-13 Identities = 76/288 (26%), Positives = 132/288 (45%), Gaps = 21/288 (7%) Query: 343 CATHGHLCQHFCEDRLGS-FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 CA + CQ C R G C CA+G L DG SC+ +GYL S ++ + Sbjct: 2155 CAQNNGGCQQLCLFRGGGRRTCACAHGM-LSEDGVSCR-----DYDGYLLYSERTILKSI 2208 Query: 402 PLADFTDGSNYSAIQKF--AGH-GTIRSIDFMHR-----NNKMFMSISDEHGDPTGELSV 453 L+D + + + I+ F A H + ++ F +R +N++F SD H +++ Sbjct: 2209 HLSD--ENNLNAPIKPFEDAEHMKNVIALAFDYRYGTKGSNRIFY--SDIHFGNIQQIND 2264 Query: 454 SDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISI-CTMSGMFCRRVIEGKE 512 G R + ENV V +A +++T + S ++ + G F R + Sbjct: 2265 DGTG-RRTIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQSRLGAFERETVITMS 2323 Query: 513 QGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRH 572 R V+ + L+ W + +++ IM A + G+ V I++D + P+ LAID+ Sbjct: 2324 GDDHPRAFVLDECQNLMFWTNWNEQHPSIMRATLSGANVLIIIDQDIRTPNGLAIDHRAE 2383 Query: 573 DVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADW 620 +YF D IER D R V++ + HP+ +A + +++W DW Sbjct: 2384 KIYFSDATLDKIERCEYDGSHRHVILKSEPVHPFGLAVYGDYIFWTDW 2431
Score = 77.4 bits (189), Expect = 9e-13 Identities = 86/333 (25%), Positives = 122/333 (36%), Gaps = 85/333 (25%) Query: 11 PLFIHILIKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCS 70 P+ IHI + + P V N C + C N L +C + G D C Sbjct: 3272 PMDIHIY--HPYRQPDVPNHPC-KTNNAGCSNLCLLSPGGGHKCACPTNFYLGSDGKTC- 3327 Query: 71 YAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFV 130 +C+ S +CKN C+ +KCD EDDC D SDE P F Sbjct: 3328 -VSNCTASQFVCKNDKCIPFWWKCDTEDDCGDRSDE----------------PEDCPEF- 3369 Query: 131 GHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVH 190 +C P + +C +G C P +CDG DC DE NC D+H Sbjct: 3370 -----KCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANC----------------DIH 3408 Query: 191 LVDPT-FFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQ--TNAPSEE 247 + P+ F N+C G C+ D C EK+C T AP++ Sbjct: 3409 VCLPSQFKCTNTNRCIPGIFRCNGQDNC-------------GDGEDEKDCPEVTCAPNQF 3455 Query: 248 EYLSGQ--------ADHMHSC-------SAAGMYSCGT---KGSEIGVCIPMNATCNGIK 289 + + D + C + +CG + + G CIP C+G Sbjct: 3456 QCAITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGED 3515 Query: 290 ECPLGDDESKHCSECARKRCDHTCMNTPHGARC 322 +C G DE K EC + C+ P+ RC Sbjct: 3516 DCGDGSDEPKE--ECDERTCE------PYQFRC 3540
Score = 77.4 bits (189), Expect = 9e-13 Identities = 92/368 (25%), Positives = 159/368 (43%), Gaps = 45/368 (12%) Query: 350 CQHFCEDRLG-SFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTD 408 C H C + +C C + +L+ D +C YE + +L + E+R + + D Sbjct: 1547 CSHLCLINYNRTLSCACPHLMKLDKDNTTC-YEF----KKFLLYARQMEIRGVDI----D 1597 Query: 409 GSNYSAIQKFA--GHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENV 466 Y+ I F + +D+ +++ SD ++ G+ V+ ++ Sbjct: 1598 NPYYNYIISFTVPDIDNVTVVDYDAVEQRIYW--SDVRTQTIKRAFINGTGVETVVSADL 1655 Query: 467 IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMR 526 ++VDW+ N+F+T + I++ + G F VI+G ++ LVVHP+ Sbjct: 1656 PNAHGLSVDWVSRNLFWTSYDTNKKQ-INVARLDGSFKNAVIQGLDKPHC---LVVHPLH 1711 Query: 527 GLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIER 586 G + W D I +ANMDGS +L N+ P LAIDY +Y+ I R Sbjct: 1712 GKLYWTDG----DNISVANMDGSNRTLLFTNQ-RGPVGLAIDYPESKLYWISSGNGTINR 1766 Query: 587 VNIDTKERRVVIS--NGVHHPYDMAYFNGFLYWADWGSESLKV------QEMTHHHSSPQ 638 N+D + V+++ + + +A L+WAD SE + E+T +S Sbjct: 1767 CNLDGSDLEVIVAVKSQLSKATALAIMGDKLWWADQASERMGTCNKKDGTEVTVLRNSTT 1826 Query: 639 VIHTFNRYPYGIAVNHSLYQTGPPSNPCL--ELECPWLCVIVPKSDFIMTAKCVCPDGYT 696 ++ Y + S+ Q G SNPC +C LC +P S+ + C+C GY+ Sbjct: 1827 LVMLMKVY------DESIQQAG--SNPCSVNNGDCSQLC--LPTSE--TSRSCMCTAGYS 1874 Query: 697 HSVTENSC 704 + SC Sbjct: 1875 LKSGQQSC 1882
Score = 76.3 bits (186), Expect = 2e-12 Identities = 93/362 (25%), Positives = 132/362 (36%), Gaps = 76/362 (20%) Query: 27 VNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGL 86 V+N T A +F C N +CIP W+CD DC DE C C G+ Sbjct: 3328 VSNCT---ASQFVCKND--KCIPFWWKCDTEDDCGDRSDEPEDCPEFKCRPGQFQCSTGI 3382 Query: 87 CVANEFKCDGEDDCRDGSDEQHCEYNI-LKSRFDGSNPS--APTTFVGH----------- 132 C F CDG++DC+D SDE +C+ ++ L S+F +N + P F + Sbjct: 3383 CTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDE 3442 Query: 133 -NGPE--CHPPRLRCR-SGQCIQPDLVCDGHQDCSGGDDE-VNCTRRGHENMQSSTD--- 184 + PE C P + +C + +CI VCD DC G DE NCT+ M D Sbjct: 3443 KDCPEVTCAPNQFQCAITKRCIPRVWVCDRDNDCVDGSDEPANCTQ-----MTCGVDEFR 3497 Query: 185 FHDDVHLVDPTFFANEDNKCRSG---------------YTMCHSGDVCIPXXXXXXXXXX 229 D + + + ++ C G Y + C+P Sbjct: 3498 CKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDND 3557 Query: 230 XXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIK 289 E++C SE E +SC G CI C+G Sbjct: 3558 CGDNSDEESCTPRPCSESE-----------------FSCAN-----GRCIAGRWKCDGDH 3595 Query: 290 ECPLGDDESKHCSECARKRCDHTCMNTPHGARCICQEGYKLAD-DGLTCEDEDECATHGH 348 +C G DE C + + C N CI AD D + DE++C T Sbjct: 3596 DCADGSDEKDCIPRCEFDQ--YQCKN----GHCIPMRWRCDADADCMDGTDEEDCGTGVR 3649 Query: 349 LC 350 C Sbjct: 3650 TC 3651
Score = 43.9 bits (102), Expect = 0.010 Identities = 33/111 (29%), Positives = 43/111 (38%), Gaps = 28/111 (25%) Query: 75 CSTSFMLCKNGL-CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHN 133 CS CK+ + C++ ++CDGE DC DGSDE +P Sbjct: 29 CSPKQFACKDQITCISKGWRCDGEKDCPDGSDE------------------SPDICPQSK 70 Query: 134 GPECHPPRLRCRSGQ-CIQPDLVCDGHQDCSGGDDE--------VNCTRRG 175 C P C + CI +C+G DC G DE NCT G Sbjct: 71 VSRCQPNEHNCLGTELCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALG 121
Score = 43.5 bits (101), Expect = 0.015 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 11/114 (9%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESG--C--SYAHHCSTSFMLC-KNG 85 TC K+F C + ++ CI W+CD DC G DES C S C + C Sbjct: 28 TC-SPKQFACKD-QITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTE 85 Query: 86 LCVANEFKCDGEDDCRDGSDE-QHCEYNILKSRFDGSNPSAPTTFVGHNGPECH 138 LC+ C+G DC DGSDE HC + G T +GP C+ Sbjct: 86 LCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALGCQHHCVPTL---SGPACY 136
Score = 43.5 bits (101), Expect = 0.015 Identities = 54/236 (22%), Positives = 81/236 (34%), Gaps = 64/236 (27%) Query: 135 PECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDP 194 P+C P C++ +CIQ CDG DC DE H++ S F Sbjct: 850 PQCQPGEFACKNNRCIQERWKCDGDNDCLDNSDEA--PELCHQHTCPSDRF--------- 898 Query: 195 TFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQA 254 KC++ + CIP E N +A Sbjct: 899 --------KCKN--------NRCIPNRWLCDGDNDCGNNEDESNSTCSA----------- 931 Query: 255 DHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCM 314 +CS +SC + G CIP++ TC+ +C D S + CA C Sbjct: 932 ---RTCS-PNQFSCAS-----GRCIPISWTCDLDDDC---GDRSDESASCAYPTCFPLTQ 979 Query: 315 NTPHGARCICQEGYKLADDGLTCEDEDECATHGHL--CQHFCEDRLGSFACKCANG 368 T + RCI + C+++++C + C H C S KC +G Sbjct: 980 FTCNNGRCI--------NINWRCDNDNDCGDNSDEAGCSHSCS----SNQFKCNSG 1023
Score = 40.0 bits (92), Expect = 0.15 Identities = 32/138 (23%), Positives = 60/138 (43%), Gaps = 4/138 (2%) Query: 519 GLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGD 578 G+ H I W+D I A D + ++ N + +A+D+I ++Y+ D Sbjct: 1922 GIDFHAENDTIYWVD--MGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTD 1979 Query: 579 VERQLIERVNIDTKERRVVISNGVHHPYDMAYF--NGFLYWADWGSESLKVQEMTHHHSS 636 +IE ++ R VVIS G+ P + G+L+W +WG + Sbjct: 1980 QGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGTER 2039 Query: 637 PQVIHTFNRYPYGIAVNH 654 +++ +P GI+V++ Sbjct: 2040 MVLVNVSISWPNGISVDY 2057
>gi|24642347|ref|NP_727914.1| CG8909-PB [Drosophila melanogaster] gi|7293154|gb|AAF48538.1| CG8909-PB [Drosophila melanogaster] Length = 2009 Score = 215 bits (547), Expect = 3e-54 Identities = 185/672 (27%), Positives = 280/672 (41%), Gaps = 107/672 (15%) Query: 26 AVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNG 85 A N T DQ F+C NG CIP W CD DC DE+ C+ C+ C +G Sbjct: 263 ARTNCTDDQ---FECLNG--FCIPRTWVCDGENDCKDFSDETHCNRT-TCTDEHFTCNDG 316 Query: 86 LCVANEFKCDGEDDCRDGSDEQHCEYNI------------------------LKSRF--D 119 C++ F+CDGE DC D SDE C I + +RF D Sbjct: 317 YCISLAFRCDGEHDCNDNSDELKCAAVINSCPEGEFKCRGGLGGAGGPSGQCILNRFRCD 376 Query: 120 GSNPSAPTTFVGHNGPE----CHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRG 175 G N + N P+ C +C G CI CD QDC GG+DE +C G Sbjct: 377 GDNDCGDWS-DEENCPQKPSLCTSNEYKCADGTCIPKRWKCDKEQDCDGGEDENDCGSLG 435 Query: 176 HENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXX 235 E+ + C S C++G CI Sbjct: 436 SEHPLT----------------------CGSDEFTCNNGR-CILKTWLCDGYPDCAAGED 472 Query: 236 EKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKG--SEIGVCIPMNATCNGIKECPL 293 E C H G + C TK + + +C+ C+G ECP Sbjct: 473 EVEC------------------HLQCDLGQFLCPTKQNLTNLKICVHQKHICDGHNECPA 514 Query: 294 GDDES-----KHCSECARKRCDHTCMNTPHGA-RCICQEGYKLADDGLTCEDEDECA-TH 346 G+DE+ + CSE + C+ C+ T G+ C C+ GY + + + C D DEC Sbjct: 515 GEDEADCPKERKCSEPS--PCEQLCIETTAGSNECACRLGYVMDKNKVNCTDIDECQYLT 572 Query: 347 GHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADF 406 +C C + +GSF C C GY L D SCK L ++ ++R++ L++ Sbjct: 573 SPVCSQKCHNTMGSFKCSCETGYILRPDLRSCKALGGAMT---LLVANRWDIRRVTLSN- 628 Query: 407 TDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENV 466 + YSAI K H I ++DF HR MF SD D + ++ + V++ + Sbjct: 629 ---NRYSAIVK-GLHNAI-ALDFHHRKGLMFW--SDVSTDVIKMVYMNGTRVRDVIKWGL 681 Query: 467 IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMR 526 +AVDWI +F+T S + + + G R VI + + R +VVHP Sbjct: 682 ESPGGIAVDWIHDLLFWTD---SGTRRVEVSNFQGNL-RTVIASYDLDKP-RAIVVHPGE 736 Query: 527 GLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIER 586 L W D + +I A MDG+Q ++++ + P+ LAID+ +Y+ D ++ IE Sbjct: 737 ALAFWSD-WGPNPKIERAYMDGTQRKVIISKGVTWPNGLAIDFPNSKIYWADAKQHAIEC 795 Query: 587 VNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRY 646 N+D +R ++S + HP+ + F +YW DW ++++ + V F+ + Sbjct: 796 SNLDGSDRNKILSTHLPHPFALTLFEDTMYWTDWNTKTVSAADKITGKEFRAVHENFH-F 854 Query: 647 PYGIAVNHSLYQ 658 P I H Q Sbjct: 855 PMDIHAYHPARQ 866
Score = 94.7 bits (234), Expect = 5e-18 Identities = 73/277 (26%), Positives = 131/277 (47%), Gaps = 14/277 (5%) Query: 350 CQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADF-TD 408 C H C S C C G L+ DG +CK +T + + ++ ++R L D D Sbjct: 884 CSHLCLPNKTSRRCGCPIGLSLKEDGKTCK----STADKLVLVARRKDIRLRHLRDNQAD 939 Query: 409 GSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIG 468 ++ I ++D+ + F+ +D + ++ + RV+ N++ Sbjct: 940 PNDVDMIVPLDNLKHAVALDWCSDTD--FIYWTDVERSTINKAHLNGSYQQRVVHSNLVS 997 Query: 469 VSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGL 528 +A+DWI +++T S + I + T +G R + E+ R +VV+P+ G Sbjct: 998 PVGLALDWITDKLYWTDPS---TNRIEVATTNGKM--RTLLIWEKLYKPRDIVVNPIEGF 1052 Query: 529 IIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVN 588 + W D + I ANMDG + + KL P+ LAIDY + +YF D + +E +N Sbjct: 1053 MFWSD-WGDDPMIERANMDGHERVTITSKKLIYPNGLAIDYEKSKIYFVDGGTKTLENMN 1111 Query: 589 IDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL 625 D R+V++ NG+ HP+ + G ++W DW ++S+ Sbjct: 1112 FDGSGRQVIL-NGLGHPFGLDVNEGRVFWTDWDTKSV 1147
Score = 79.7 bits (195), Expect = 2e-13 Identities = 84/381 (22%), Positives = 168/381 (44%), Gaps = 38/381 (9%) Query: 340 EDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVR 399 ++ C + C H C ++C+C G L + + + PE YL I+L + Sbjct: 1488 KNACGNNNGNCSHLCLRNPSGYSCQCPIGLRLRQNSTT---QCQNLPEDYLLIALRSGIG 1544 Query: 400 QMPL--ADFTDGSNYSAIQKFAG-HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDN 456 + L DF D + G HG + +D+ +R N +F +D + D +++ + Sbjct: 1545 MISLNSGDFMD-----VVLPINGVHGAV-VLDYHYRKNLLFF--ADVNLDVIRRVNLLNL 1596 Query: 457 GLMRVL-RENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQ 515 +V+ +V+ + +AVDWI N+++ S + I + + G +R++E + Sbjct: 1597 TESKVIVGTDVLTPNGIAVDWIADNLYW---SDTDRKLIEVSRLDGSCRKRIVE--DNLG 1651 Query: 516 SYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVY 575 R L+VHP + + W D + +I + +DGS +++ + + P+ L ID+ + Sbjct: 1652 DPRSLIVHPKKAYLFWSD-WSSPAKIERSYLDGSNRTVIITSGIGFPTGLTIDFTNRRLL 1710 Query: 576 FGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL-KVQEMTHH- 633 + D I +V+ + K R+ ++ HP+ + F ++W DW ++S+ + Q++ Sbjct: 1711 WADALEDNIGQVDFNGKRRQTIVPYA-PHPFGLTLFENSIFWTDWYNKSVYRSQKLARSG 1769 Query: 634 HSSPQVIH------------TFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKS 681 + +P + + +R P +VNH G ++ CL ++C Sbjct: 1770 YGNPFEVRDALSGALDIRAVSLSRQPK--SVNHCAQDNGGCTHLCLNRNVDYVCACPDVM 1827 Query: 682 DFIMTAKCVCPDGYTHSVTEN 702 D A + P H+ EN Sbjct: 1828 DPKDVACSIKPKVLVHANLEN 1848
Score = 79.7 bits (195), Expect = 2e-13 Identities = 68/282 (24%), Positives = 138/282 (48%), Gaps = 20/282 (7%) Query: 350 CQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDG 409 C H C S+ C C G +L+ D H+C + P Y+ + ++RQ+ L DF Sbjct: 1192 CSHLCLLNPTSYTCACTVGVQLKEDRHTC----SEGPTQYILFAHRIDIRQISL-DFDHL 1246 Query: 410 SNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGL--MRVLRENVI 467 + + ++D + ++ S + E+ +S S +GL +++ +++ Sbjct: 1247 ID--VVLPLPPISNAVALDVDRKTGYIYWSDTIENVI----MSSSPDGLHVQKIVGDSLE 1300 Query: 468 GVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRG 527 + VD IG +++ + + I + ++ G R VI K+ +S RGL + G Sbjct: 1301 NPDGLVVDSIGRTIYW---ADAGRHTIEVASLDGS-NRHVIAYKDL-ESPRGLALDYEAG 1355 Query: 528 LIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERV 587 L+ W D + Y +I +++DG++ ++ L P+ L++D +Y+ D + I+ Sbjct: 1356 LLFWTD-WGHYRKIERSHLDGNERSRIVTANLGWPNGLSLDLKSKRIYWVDARLKTIDSC 1414 Query: 588 NIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQE 629 + +R++++S+ +HHPY +A + +YW DW S++L + E Sbjct: 1415 DYTGNQRKLIMSS-LHHPYALALSDDNIYWTDWKSKALHMTE 1455
>gi|24640820|ref|NP_572563.2| CG12139-PB [Drosophila melanogaster] gi|7291057|gb|AAF46494.1| CG12139-PB [Drosophila melanogaster] Length = 4547 Score = 211 bits (536), Expect = 5e-53 Identities = 206/786 (26%), Positives = 312/786 (39%), Gaps = 122/786 (15%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGC---SYAHHCSTSFMLCKN 84 N C+ +F CGN RCIP +W CD DC DE+ CS S C N Sbjct: 3643 NCPKCNPETDFKCGNN--RCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGN 3700 Query: 85 GLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRC 144 G C+++ ++CD EDDC D SDE HCE G +C +C Sbjct: 3701 GKCISSRWQCDHEDDCGDNSDEMHCE-----------------------GYQCKNGTFQC 3737 Query: 145 RSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKC 204 SG CI CDG +DC DEV C R F + + F N +N C Sbjct: 3738 ASGHCIASYFRCDGDRDCRDMSDEVGCPPR----------FPGGRYCPESRFQCN-NNLC 3786 Query: 205 RSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAP------------------SE 246 S +C D C + Q + S+ Sbjct: 3787 VSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQCSNERCVARYQICDGVDNCGDGSD 3846 Query: 247 EEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE-----SKHC 301 E ++ A C Y C K CI + C+ +C DE + C Sbjct: 3847 ENNMTLCASKQKPCDLYTQYQCANKH-----CIERSQVCDFSDDCGDASDELGCHHTSSC 3901 Query: 302 SECARKRCDHTCMN-TPHGARCICQEGYKL-ADDGLTCEDEDECATHGHLCQHFCEDRLG 359 SE R C C N T G C C GY + AD+ C D DEC T H C H C + G Sbjct: 3902 SEANRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDVDECLTRQHTCSHQCHNLNG 3961 Query: 360 SFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKF- 418 +++C C G+ L TDG S A LF++ G E+R G N+ ++F Sbjct: 3962 TYSCSCREGFHL-TDGASGVCRAEKEDVILLFVN-GQEIR---------GLNWHKSEEFA 4010 Query: 419 --AGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRV---LRENVIGVSN-- 471 A I ++D+ + +F + S + + + +G ++ N+ G S Sbjct: 4011 VIAAEKRIEALDYDAQQQIVFWADSYDKTIKRSYMVNAIDGRAKIGFAQDLNMKGGSKPT 4070 Query: 472 -VAVDWIGGNVFFTQ---KSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRG 527 VAVDW+ N+++T+ P + + G + R ++ + + + V+P G Sbjct: 4071 AVAVDWLASNLYWTEMDRTGSKPRGRVMVAKTDGRYRRSIVNAGLEVPT--SIAVNPQLG 4128 Query: 528 LIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIR-HDVYFGDVERQLIER 586 I W D+ +I ++ MDGS+ R L+ + P+ L IDY + H +Y+ D + IE Sbjct: 4129 RIYWSDA-GSAPKIEVSWMDGSKRRPLITEMIRHPAGLTIDYSQDHIIYWVDTKLNAIES 4187 Query: 587 VNIDTKERRVVI-SNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNR 645 + D R+ ++ + + HP + F ++W + L V++ V+H + Sbjct: 4188 MRADGSRRKAIVRGDQLRHPVSLDLFESNMFWMTRDTGEL-VRQDKFGRGVQVVLHRYIV 4246 Query: 646 YPYGIAVNH-SLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSC 704 P G+ V H Y T P NPC C LC++VP +C CPD + S Sbjct: 4247 NPSGLKVYHDKRYNTSLP-NPCDNSTCSHLCLLVPGGH-----RCACPDASGPPPSHRST 4300 Query: 705 IPPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPY 764 + E+ I C NGG C+E + G ++C+C + Sbjct: 4301 AEVICNAAAEHPRPAPRI------------CPCQNGGLCKE--DAQG---ELLCECRTQF 4343 Query: 765 DGQYCE 770 G++CE Sbjct: 4344 VGEHCE 4349
Score = 184 bits (468), Expect = 5e-45 Identities = 187/738 (25%), Positives = 291/738 (39%), Gaps = 129/738 (17%) Query: 18 IKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCST 77 + N+ + TC + EF C +G RCIP ++CD DC DE C C T Sbjct: 953 LDNSDEEQNCTKPTCG-SNEFQCRSG--RCIPQNFRCDQENDCGDNSDEQECGNV-TCGT 1008 Query: 78 SFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSA----PTTFVGHN 133 S C NG C+ N +KCD E+DC D SDE + F + P P ++V Sbjct: 1009 SQFACANGRCIPNMWKCDSENDCGDSSDEGDFCAEKTCAYFQFTCPRTGHCIPQSWVCDG 1068 Query: 134 GPECH--------PP------RLRCRS-GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHEN 178 +C PP + +C QC++ CDG DC+ G DEV C G Sbjct: 1069 DDDCFDKQDEKDCPPISCLANQFKCADLRQCVEESYKCDGIPDCNDGSDEVGCPSMGPNQ 1128 Query: 179 MQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKN 238 F C S CIP E++ Sbjct: 1129 CNLEKHFR------------------------CKSTGFCIPIAWHCDGSNDCSDHSDEQD 1164 Query: 239 C-------------QTNAPSEEEYLSGQAD--------HMHSCSAA------GMYSCGTK 271 C TN + G+ D H+C G + C Sbjct: 1165 CGQITCAQNFFKCNNTNCVFKAYICDGKDDCGDNSDEGAEHACVPPPFKCPHGQWQCPGV 1224 Query: 272 GSEIGVCIPMNATCNGIKECPLGDDESKHC--SECARK--RCDHTCMNTPHGARCICQEG 327 C+ + + C+ +CP G DE + C +EC + +C C TP+GA C+C G Sbjct: 1225 SER---CVNITSVCDDTPDCPNGSDEGEGCDLAECEHQAGQCSSFCQKTPNGALCVCPPG 1281 Query: 328 YKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPE 387 ++ +DG TC D +EC G LC C + GS+ C C +GY LE + H+CK A Sbjct: 1282 SEIGEDGYTCIDSNECDPPG-LCSQQCTNTKGSYFCSCTDGYVLEPNKHTCK--AVNHTA 1338 Query: 388 GYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDP 447 +L IS + +AD + + + + N + + S+ H Sbjct: 1339 AFLIIS---NRHSILVADLKEQG-------------LERVPIIVEN--VVATASNMH--- 1377 Query: 448 TGELSVSDNGLMRVLR-------ENVIG-----VSNVAVDWIGGNVFFTQKSPSPSAGIS 495 TG + SD L ++ R + +I V +A DWI N+++ S I Sbjct: 1378 TGTIFWSDMKLKKISRLDRGMEPQEIINTGLDLVEGLAYDWIAQNLYWLD---SKLNTIE 1434 Query: 496 ICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGL--IIWIDSYQKYHRIMMANMDGSQVRI 553 + +G R++ +E RG+ + P G I W D + + R+ MDG+ + Sbjct: 1435 VSAENG--SNRLVLVRENITQPRGMCIDPSPGARWIFWTD-WGENPRVERIGMDGTMRKT 1491 Query: 554 LLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH--HPYDMAYF 611 +++ K+ P+ L +D VYF D + I+ + R+ V+++ + HP+ ++ F Sbjct: 1492 IINTKIYWPNGLTLDIATKRVYFADSKLDFIDFCYYNGTGRQQVLASSHYLLHPHSLSLF 1551 Query: 612 NGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELEC 671 LYW D + + V H ++ P I V+H+ Q P NPC C Sbjct: 1552 EDTLYWTDRQLNRVLSANKFRGKNQTVVSHLISQ-PLSIHVHHASLQPMTP-NPCAGSRC 1609 Query: 672 PWLCVIVPKSDFIMTAKC 689 LC++ P + + KC Sbjct: 1610 QHLCLLSPSAPEGYSCKC 1627
Score = 181 bits (459), Expect = 5e-44 Identities = 190/722 (26%), Positives = 293/722 (40%), Gaps = 91/722 (12%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESG--C-SYAHHCSTSFMLCKNGLC 87 TC F C N RCIPA W CD DC G DE C S C C NG C Sbjct: 2769 TC-PTNSFRCPNH--RCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNC 2825 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 + + CDG++DC D SDE + + + + T F C + R+ Sbjct: 2826 IPRIYICDGDNDCLDNSDEDN------RHQCNDRKCDEETEFT------CVENKSWQRA- 2872 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHD--DVHLVDPTFFANEDNKCR 205 QCI +CDG DC G DE D + ++ + + DN C Sbjct: 2873 QCIPKKWICDGDPDCVDGADENTTLHNCATQQPCGEDMFTCGNGRCINKGWICDHDNDCG 2932 Query: 206 SGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAA-- 263 G G C Q+ E++ DH A Sbjct: 2933 DG---TDEGKFCNSKYKTCSAQEFTCQNFKCIRNQSRCDGEDDC----GDHSDEVGCAKE 2985 Query: 264 ------GMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCS--ECAR---KRCDHT 312 G ++C G CI N CN +C DE HC+ ECA+ +C H Sbjct: 2986 NITCPQGQFACTN-----GQCIDYNLVCNKYPDCADESDEPAHCNVDECAKVEINQCGHK 3040 Query: 313 CMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANG-YEL 371 C++T G C C EGYKL DG C D DEC C C + G F CKC YE Sbjct: 3041 CVDTLTGYYCDCNEGYKLLADGKACADVDECLEQPGACSQHCSNTPGGFYCKCDETYYER 3100 Query: 372 ETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMH 431 + D H+CK + P +L + VR M + DG Y+ + + + ++DF Sbjct: 3101 QNDEHTCKRKDKIPP--WLIFTNKYYVRNMSV----DGHQYNLMHQ--DLMNVVALDFDI 3152 Query: 432 RNNKMFMS-------ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFT 484 R M+ ++G+ E+ V+R + G+ +A+DW+G +++ Sbjct: 3153 REEYMYFCDVTAKTIFRAKYGEADDEMPPEREA---VIRHDSHGLEGIAIDWVGRKLYWL 3209 Query: 485 QKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMA 544 + S + + + G + + G R +VVHP G ++ S+ I Sbjct: 3210 DRH---SKNLDVSELDGSKRKTLRSGVVDP---RAIVVHPGIGY-LYFTSWHLQAYIAKM 3262 Query: 545 NMDGSQVRILL--DNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG- 601 MDGS +L ++ + P+AL+IDY +Y+ D I +++ + R V+S Sbjct: 3263 GMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHTVLSGSK 3322 Query: 602 VHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGP 661 V H + ++ F+ ++YW+DW +++ V+ H ++ V+ PY + +NH L Q P Sbjct: 3323 VPHVFALSLFDDYIYWSDWNLKAI-VRANKFHGANYTVLRNTTHRPYDLHINHPLRQL-P 3380 Query: 662 PSNPCLELE--CPWLCVIV--PKSDFIMTA----------KCVCPDGYTHSVTENSCIPP 707 +NPC C LC+I P+S ++ KC CP+ + + +C+ Sbjct: 3381 YTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFYLARDMKTCVAN 3440 Query: 708 VT 709 T Sbjct: 3441 CT 3442
Score = 90.1 bits (222), Expect = 1e-16 Identities = 97/394 (24%), Positives = 163/394 (41%), Gaps = 39/394 (9%) Query: 343 CATHGHLCQHFC--------EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISL 394 C + C H C LG F C C+ GY+LETD CK + +L S Sbjct: 541 CGNNNGGCNHMCIVTAVKGAPTGLG-FRCACSTGYQLETDLKLCKPVSE-----FLMYSQ 594 Query: 395 GGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVS 454 ++ L +G + + + + +DF R+ F+ SD D + + Sbjct: 595 QRFIKGKVLEPVIEGFSDAIMPVVSRRARFVGLDFDARDE--FIYYSDVLQDVIYRVHRN 652 Query: 455 DNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQG 514 G VL GV +AVDW N+++ S +++ + + RR + + Sbjct: 653 GTGREIVLASQNEGVEGLAVDWASKNLYYID---SRKGTLNVLSTRNVTHRRTL--LKNL 707 Query: 515 QSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDV 574 + R +VVHP RG I+ + + I AN DGS + + + L P+ L+ID+ V Sbjct: 708 KRPRAIVVHPNRGF-IFFSEWDRPANITRANTDGSGLLVFKNVTLGWPNGLSIDFKEDRV 766 Query: 575 YFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSES-LKVQEMTHH 633 Y+ D ++ N+D + + V S V HP+ + N ++Y DW ++ +++ ++T Sbjct: 767 YWCDALLDHVQHANLDGTDIKTVNSRLVRHPFSIVIHNDWMYITDWRLDAIIRLHKLTGE 826 Query: 634 HSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE--CPWLCVIVP-----KSDFIMT 686 V YG+ V Q + PC C +C VP +D + T Sbjct: 827 QEEMMVREPQTNRLYGVKVYSHEVQRIADTQPCHRNNGGCQKICFAVPIGASNGTDGVTT 886 Query: 687 ---------AKCVCPDGYTHSVTENSCIPPVTIE 711 ++C CP G + + SCIP + E Sbjct: 887 SSPSFGRLQSRCSCPYGERLADDQVSCIPDPSAE 920
Score = 84.7 bits (208), Expect = 6e-15 Identities = 87/353 (24%), Positives = 130/353 (36%), Gaps = 82/353 (23%) Query: 40 CGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDD 99 CG +CIP W+CD DC G DE HC CKN C + CDG DD Sbjct: 3448 CGGRDEKCIPWFWKCDGEKDCKDGSDEPATCAPRHCRAGTFQCKNTNCTPSATICDGVDD 3507 Query: 100 CRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQCIQPDLVCDG 158 C D SDEQ+C+ C +C+ SG+CI CDG Sbjct: 3508 CGDRSDEQNCDL------------------------PCPLSDFKCKSSGRCILDSWRCDG 3543 Query: 159 HQDCSGGDDE--VNCTRRGHENMQSST-------------DFHDDV--HLVDPTFFANED 201 DC G DE C +R + + DF +D +P + + Sbjct: 3544 DADCKDGSDEDPAVCFKRTCDPKTEFSCKNGRCIPQLWMCDFDNDCGDDSDEPAYMCRQR 3603 Query: 202 NKCRSGYTMC--HSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHS 259 N C +G+ C S CIP + +C+ N+ E + Sbjct: 3604 N-CTTGWQRCPGQSNYRCIP---------KWLFCDGKDDCRDNSDELPE-------NCPK 3646 Query: 260 CSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTPHG 319 C+ + CG CIP C+ +C DE++ + + C + +G Sbjct: 3647 CNPETDFKCGNNR-----CIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNG 3701 Query: 320 ARCICQEGYKLADDGLTCEDEDECATHG---HLCQHFCEDRLGSFACKCANGY 369 +CI C+ ED+C + H + C++ G+F +CA+G+ Sbjct: 3702 -KCISSR--------WQCDHEDDCGDNSDEMHCEGYQCKN--GTF--QCASGH 3741
Score = 82.0 bits (201), Expect = 4e-14 Identities = 108/425 (25%), Positives = 162/425 (38%), Gaps = 76/425 (17%) Query: 18 IKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEW--QCDNVADCDKGRDESGCSYAHHC 75 + N + A N+TC +A +F C NG RCI W D+ + D + C+Y H C Sbjct: 2590 VVNEGRMCAPRNNTC-EASKFYCKNG--RCISRMWSCDGDDDCGDNSDEDPNYCAY-HSC 2645 Query: 76 STSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEY-NILKSRFDGSN----PSA----- 125 S + C NG C+ +KCD E+DC+DGSDE C Y + F +N P A Sbjct: 2646 SPNEFRCNNGRCIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCANGRCIPQAQVCNG 2705 Query: 126 -------PTTFVGHN----GPECHPPRLRC-RSGQCIQPDLVCDGHQDCSGGDDE--VNC 171 T+ H C L+C ++ C++P +CDG DC DE ++C Sbjct: 2706 VNDCKDNATSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHC 2765 Query: 172 TRR----------GHENMQSS-----TDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDV 216 +R H + ++ D D P + +E C C +G+ Sbjct: 2766 GQRTCPTNSFRCPNHRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGN- 2824 Query: 217 CIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSC-GTKGSEI 275 CIP + +C N+ + + C ++C K + Sbjct: 2825 CIP---------RIYICDGDNDCLDNSDEDNRHQCND----RKCDEETEFTCVENKSWQR 2871 Query: 276 GVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTPHGARCI-----------C 324 CIP C+G +C G DE+ CA ++ M T RCI C Sbjct: 2872 AQCIPKKWICDGDPDCVDGADENTTLHNCATQQPCGEDMFTCGNGRCINKGWICDHDNDC 2931 Query: 325 QEGYKLADDGLTCEDE-DECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEAT 383 +G D+G C + C+ CQ+F R S C + +D C E Sbjct: 2932 GDG---TDEGKFCNSKYKTCSAQEFTCQNFKCIRNQS-RCDGEDDCGDHSDEVGCAKENI 2987 Query: 384 TTPEG 388 T P+G Sbjct: 2988 TCPQG 2992
Score = 81.6 bits (200), Expect = 4e-14 Identities = 85/346 (24%), Positives = 156/346 (45%), Gaps = 26/346 (7%) Query: 343 CATHGHLCQHFCEDRLGSF-ACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 C T+ C+H C G+ C C GY E + + Y+ + +S +R Sbjct: 1929 CQTNNGGCKHLCIPGPGATRTCACGIGYRKENEINCVAYKI------FAVVSQLDMIRGY 1982 Query: 402 PLADFTDGSNYSAIQKFAGHG-TIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNG--L 458 L+D ++ A+ +G G I +D M+R ++ + + G G NG L Sbjct: 1983 SLSDSSE-----AMVPISGPGHHILHVDVMYREQWIYWAEYNR-GYWNGIFRSRPNGTDL 2036 Query: 459 MRVLRENV--IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQS 516 V+++ + G+ + +DW+ GN++FT P + + +C + G R + K + Sbjct: 2037 QHVVKDGIGSNGIRGLTIDWVAGNMYFTNVYPHENY-VEVCWLDG--SNRKVLVKTTTDA 2093 Query: 517 YRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYF 576 R L V+P++ L+ WID Y ++ RI A +DGS+ L+ + + +P L ID HD+Y+ Sbjct: 2094 PRELAVNPIKRLLYWID-YGQHPRIGKALLDGSKWTPLVTSGISLPRDLTIDMQTHDIYW 2152 Query: 577 GDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSS 636 D + I++++ + R+ +I + +P +A + +YW D ++ + + Sbjct: 2153 VDSKLDTIQKISYNGANRK-IIRRDLPNPMGIAVYLNDVYWVDRNLMTVFKASKHSANET 2211 Query: 637 PQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLEL---ECPWLCVIVP 679 + T IA+ + Q +NPC L C LC P Sbjct: 2212 ATSVRTNLEKLRDIAIYNINNQPQDDTNPCAHLGNGGCDQLCFSFP 2257
Score = 72.8 bits (177), Expect = 2e-11 Identities = 45/137 (32%), Positives = 62/137 (45%), Gaps = 20/137 (14%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F C NG L+CI A +C++ DC DE GC++ C + C N LC+ F CDG Sbjct: 74 QFRCANG-LKCIDAALKCNHRDDCGDNSDEQGCNFP-PCHHAQFRCTNALCIPYNFHCDG 131 Query: 97 EDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVC 156 DC D SDE +C T + P + +CI +C Sbjct: 132 YHDCADKSDEANC-----------------TAIACPDNKHLCPRGGASGTPKCILKSQLC 174 Query: 157 DGHQDCS-GGDDEVNCT 172 DG +DC G D+E NC+ Sbjct: 175 DGKRDCEDGSDEETNCS 191
Score = 64.7 bits (156), Expect = 6e-09 Identities = 69/303 (22%), Positives = 126/303 (41%), Gaps = 44/303 (14%) Query: 338 EDEDECATHGH-----LCQHFCEDRLGS-------FACKCANGYELETDGHSCKYEATTT 385 +D + CA G+ LC F D S F C+CA G +L D C+ Sbjct: 2236 DDTNPCAHLGNGGCDQLCFSFPPDGGASGTSGGRNFRCECATG-KLSADERKCE-----V 2289 Query: 386 PEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMS------ 439 YL + E+R + L + ++ + + +DF +N+M + Sbjct: 2290 VNEYLVFATRTEIRAVNLDPHSTEVPFTPLTNLT---NVVGLDFDFAHNRMLYTQIRPWA 2346 Query: 440 -ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICT 498 I+ + G ++ V+ I +A DW +++T S + +++ Sbjct: 2347 KIAYTKANKPGHDDIT------VVLNKGINPEGIAYDWTQQKIYWTDSSNNSIYAMNLDG 2400 Query: 499 MSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWID--SYQKYHRIMMANMDGSQVRILLD 556 + RV + R +V+ P G + + D + +I M GS R ++D Sbjct: 2401 SELVMIARV-------ERPRAIVLDPCNGTLFFTDWGRFGTSGKIFRTTMAGSLKRAIVD 2453 Query: 557 NKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLY 616 L PS LAIDY +Y+ D R+ IER ++D + R ++++ + +P+ + F ++Y Sbjct: 2454 KDLSQPSGLAIDYDERRLYWTDAVREKIERSDLDGQNRELLVAATI-YPFAITVFRNYIY 2512 Query: 617 WAD 619 W D Sbjct: 2513 WTD 2515
Score = 62.0 bits (149), Expect = 4e-08 Identities = 78/278 (28%), Positives = 95/278 (34%), Gaps = 83/278 (29%) Query: 85 GLCVANEFKCDGEDDCRDGSDEQHCE-----------YNILK---------SRFDGSNPS 124 G CV E +CDG DCR G DE C N LK R D + S Sbjct: 41 GPCVPKEKRCDGYLDCRTGRDEVGCSGVACRLDQFRCANGLKCIDAALKCNHRDDCGDNS 100 Query: 125 APTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTD 184 G N P CH + RC + CI + CDG+ DC+ DE NCT + Sbjct: 101 DEQ---GCNFPPCHHAQFRCTNALCIPYNFHCDGYHDCADKSDEANCT---------AIA 148 Query: 185 FHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAP 244 D+ HL P A+ KC +C C E NC Sbjct: 149 CPDNKHLC-PRGGASGTPKCILKSQLCDGKRDC------------EDGSDEETNCS---- 191 Query: 245 SEEEYLSGQADHMHSCSAAGM-YSCGTKGSEIGVC--------IPMNATCNGIKECPLGD 295 + SC A + CG + GVC P N TC + EC Sbjct: 192 ------------IASCPALSCEFKCGPSLTG-GVCYCKPGQSLAPDNRTCVDLDECA--- 235 Query: 296 DESKHCSECARKRCDHTCMNTPHGARCICQEGYKLADD 333 E H CD C NT C C +GY L +D Sbjct: 236 -EWGH--------CDQLCTNTLGSYTCQCAQGYTLIND 264
Score = 51.2 bits (121), Expect = 7e-05 Identities = 43/133 (32%), Positives = 55/133 (41%), Gaps = 21/133 (15%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNG-- 85 N C A +F C N CIP + CD DC DE+ C+ A C + LC G Sbjct: 106 NFPPCHHA-QFRCTNA--LCIPYNFHCDGYHDCADKSDEANCT-AIACPDNKHLCPRGGA 161 Query: 86 ----LCVANEFKCDGEDDCRDGSDEQ-HCEYNILKSRFDGSNPSAPTTFVGHNGPECHPP 140 C+ CDG+ DC DGSDE+ +C S P+ F GP Sbjct: 162 SGTPKCILKSQLCDGKRDCEDGSDEETNCSI--------ASCPALSCEF--KCGPSLTGG 211 Query: 141 RLRCRSGQCIQPD 153 C+ GQ + PD Sbjct: 212 VCYCKPGQSLAPD 224
>gi|17508271|ref|NP_492127.1| Low-density lipoprotein Receptor Related LRP-1, EGF motif related EGF-4 (lrp-1) [Caenorhabditis elegans] gi|1708868|sp|Q04833|LRP_CAEEL Low-density lipoprotein receptor-related protein precursor (LRP) gi|1078879|pir||A47437 LDL-receptor-related protein - Caenorhabditis elegans gi|156360|gb|AAA28105.1| LDL receptor-related protein [Caenorhabditis elegans] gi|3876533|emb|CAA98124.1| C. elegans lrp-1 protein (corresponding sequence F29D11.1) [Caenorhabditis elegans] Length = 4753 Score = 211 bits (536), Expect = 6e-53 Identities = 199/726 (27%), Positives = 302/726 (41%), Gaps = 121/726 (16%) Query: 40 CGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHH-----CSTSFML-CKNGLCVANEFK 93 C +G RCIP WQCD DC G DE+ + C ++ C N C++ F Sbjct: 2968 CPSG--RCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFI 3025 Query: 94 CDGEDDCRDGSDEQ---------------HCEYN--ILKSRF---------DGSNPSA-- 125 CDGEDDC DGSDE HC N + + ++ DG A Sbjct: 3026 CDGEDDCGDGSDEHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGG 3085 Query: 126 ---PTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDE-VNCTRRGHENMQS 181 T EC+ RC + CI CDG DC G DE NCT Sbjct: 3086 EDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSS------ 3139 Query: 182 STDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQT 241 P FF ++KC C D C EK+C Sbjct: 3140 ----------CQPDFFQCANHKCVPNSWKCDGNDDC-------------EDGSDEKDCPK 3176 Query: 242 NAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHC 301 N+ S A CS G + C + G CI C+ +C DES C Sbjct: 3177 NSAS--------AQKASKCS-NGQFQCTS-----GECIDDAKVCDRNFDCTDRSDESSLC 3222 Query: 302 --SECA---RKRCDHTCMNTPHGARCICQEGYKL-ADDGLTCEDEDECATHGHLCQHFCE 355 EC+ + C+ CM+ G +C C EG+ + D +C + +EC C C+ Sbjct: 3223 FIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCD 3282 Query: 356 DRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAI 415 D++GS+ C C +GY+L +D HSCK PE + ++ +R++ + DG+ Y Sbjct: 3283 DKIGSYKCGCVDGYQLSSDDHSCK-RTEMEPEPFFLLANKHYIRKISI----DGNKYELA 3337 Query: 416 QKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMR---VLRENVIGVSNV 472 + G + S+D K ++ + +L D+ L VLR NV G + Sbjct: 3338 AQ--GFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGI 3395 Query: 473 AVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWI 532 AVDW+G ++ + I +C + G FC+ +I +++ Q + +VVHP +G + + Sbjct: 3396 AVDWVGRKLYMLNRQ---ERSIRVCELDGRFCKTLI--RDRIQQPKAIVVHPGKGYLFFT 3450 Query: 533 D-SYQKYHRIMMANMDGS-----QVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIER 586 + S Q Y I +DGS + L ++ L P+A+AIDY +++GD I Sbjct: 3451 EWSLQPY--IGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGF 3508 Query: 587 VNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWG-SESLKVQEMTHHHSSPQVIHTFNR 645 ++ D RR + + H M F+ +LYWADW E L+ + T + + ++ + Sbjct: 3509 MDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNET--ILKKTVQ 3566 Query: 646 YPYGIAVNHSLYQTGPPSNPCLELE--CPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENS 703 P + + H + Q P NPC + C LC+I + C CPD + + + Sbjct: 3567 LPNDLRIVHPMRQPAYP-NPCGDNNGGCSHLCLIGAGGN---GYTCSCPDQFVLLSDQKT 3622 Query: 704 CIPPVT 709 C P T Sbjct: 3623 CEPNCT 3628
Score = 189 bits (479), Expect = 2e-46 Identities = 188/692 (27%), Positives = 283/692 (40%), Gaps = 104/692 (15%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESG--CSYAHHCSTSFMLCKNG- 85 N+TC A +F C NG RCIP W CD DC G DE C CS C NG Sbjct: 1184 NATC-AANQFSCANG--RCIPIYWLCDGDNDCYDGTDEDKERCPPV-QCSALQFRCANGR 1239 Query: 86 LCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRC- 144 CV CDG+ DC DGSDE C C P + +C Sbjct: 1240 QCVPLRNHCDGQSDCEDGSDEDSCAV---------------------TAESCTPDQFKCV 1278 Query: 145 RSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKC 204 SG CI CDG QDC G DE P F +C Sbjct: 1279 SSGLCIPASWKCDGQQDCDDGSDE-------------------------PKFGCTSGRQC 1313 Query: 205 RSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAG 264 S C +G CI E +C S+E G M++ Sbjct: 1314 SSDQFKCGNGR-CI---------LNNWLCDGENDCGDG--SDESSERGCKTSMNARKCPF 1361 Query: 265 MYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSE--CARKR--CDHTCMNTPHGA 320 + E CIP++ C+G CP G DE C+ C+ R C C N+P+G Sbjct: 1362 EHVACENDQE--TCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGP 1419 Query: 321 RCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKY 380 C C G +L + CE E+EC C C+D F C C GYEL+ D +CK Sbjct: 1420 ICSCPFGEQLVNK-TKCEPENECLDSSS-CSQRCKDEKHGFTCSCDEGYELDVDKRTCKV 1477 Query: 381 EATTTPEGYLFISLGGEVRQMPLADFTDGS--NYSAIQKFAGHGTIRSIDFMHRNNKMFM 438 A + +++S + ++D N+ + + D + ++++ Sbjct: 1478 -ADNVKDTRIYVSNRNRIY------YSDHKLDNWHTFGAIVENAIALAWDSL--TDRIYW 1528 Query: 439 SISDEHGDPTGELSVSDNGLMRV--LRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISI 496 S E LS + NG + + + +A+DW+G N+++ S + I + Sbjct: 1529 SDIRE----KKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNT---IEV 1581 Query: 497 CTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLD 556 + R ++ + Q RG+ V P +G++ W D + + I A+MDG+ +I++ Sbjct: 1582 ANLEDPKQRTLLVHQNVSQP-RGIAVDPRKGVMFWTD-WGQNPCIERASMDGTDRQIIVK 1639 Query: 557 NKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNGF 614 K+ P+ +A+DY VYF D + I+ VN D R V+++ V HP+ +A F Sbjct: 1640 TKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDM 1699 Query: 615 LYWADWGSESLKV-QEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPW 673 +Y++D + L+V + + +S HTF++ G+ H + Q +NPC C Sbjct: 1700 MYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSK-ALGVVAVHPVLQPVIKNNPCSTNPCSH 1758 Query: 674 LCVIVPKSDFIMTAKCVCPDGYTHSVTENSCI 705 LC++ K+ F C CP G + CI Sbjct: 1759 LCLLNNKNTF----TCKCPMGEKLDASGKKCI 1786
Score = 166 bits (419), Expect = 2e-39 Identities = 180/725 (24%), Positives = 284/725 (39%), Gaps = 131/725 (18%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGL-- 86 +S C++ +F C +G +CI EW+CD DC G DE C + C + C Sbjct: 50 SSVCNE-NDFRCNDG--KCIRTEWKCDGSGDCSDGEDEKDCPHP-GCKSDQWQCDTYTWH 105 Query: 87 ---CVANEFKCDGEDDCRDGSDEQHCEYNIL-----------------------KSRFDG 120 C+A +CD DC DGSDE+ C + + ++D Sbjct: 106 SVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDC 165 Query: 121 SNPSAPTTFVGHNGPECHPPRLRCR-SGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENM 179 + S N C + RC QCIQ VCDG +DC+ G DE + Sbjct: 166 RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC------- 218 Query: 180 QSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC 239 E KC + C + C P E C Sbjct: 219 --------------------EFKKCTANEFQCKNKR-CQPRKFRCDYYDDCGDNSDEDEC 257 Query: 240 QTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESK 299 + C G ++C G CI C+G K+C G DE + Sbjct: 258 GE----------------YRC-PPGKWNCPGTGH----CIDQLKLCDGSKDCADGADE-Q 295 Query: 300 HCSE--CARKRCDHTCMNTPHGARCICQEGYKLADD-GLTCEDEDECATHGHLCQHFCED 356 CS+ C C C +PHG C C GYKL D TC D +ECA G+ C C + Sbjct: 296 QCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGY-CDQLCAN 354 Query: 357 RLGSFACKC-ANGYELETDGHSCKYEATTTPEGYLFISLGGEV-----RQMPLADFTDGS 410 F C C + + L+ + K T GY + ++ R+ L + Sbjct: 355 HRPGFTCSCLGDCFTLQMEHGPGKDNLTM--RGYCVSNNADKMKLFVARREGLYRLNPKN 412 Query: 411 NYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHG------DPTGELSVSDNGLMRVLRE 464 ++K A I IDF + + K+F + H D GE+S + ++ + Sbjct: 413 PDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEIS----QIKKLSLK 468 Query: 465 NVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHP 524 +++ +AVDWI ++ + S S I + + G RR + + + + P Sbjct: 469 SLVYPRCLAVDWITNTLYIIE---SGSRRIDVSSYDGE--RRTVLLADGLTLPLDIALDP 523 Query: 525 MRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLI 584 +RG + + + ++ A MDG+ R L++ S + +D VY+ D + + Sbjct: 524 LRGEMFFTNQL----KLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRL 579 Query: 585 ERVNIDTKERRVVIS--NGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHT 642 E ++ +RR+V N V HP+ +A F+ +LYW DW L V ++ S +++ + Sbjct: 580 ESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDW--TRLGVIQVEKFGSDTKLLWS 637 Query: 643 ---FNRYPYGIAVNHSLYQTGPPS---------NPCLELECPWLCVIVPKS-DFIMTAKC 689 N +P GI+ H + Q GP NPC +C +C++ + F + KC Sbjct: 638 NTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKC 697 Query: 690 VCPDG 694 CP G Sbjct: 698 ACPIG 702
Score = 130 bits (327), Expect = 8e-29 Identities = 204/854 (23%), Positives = 328/854 (38%), Gaps = 170/854 (19%) Query: 35 AKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGL-CVANEFK 93 A+EF C N +CI W+CDN DC G DE+ C + C + C+ N Sbjct: 3755 AEEFRCNNN--KCIAKAWRCDNDDDCGDGSDETPECAQIECKKGWTRCSSSYRCIPNWAF 3812 Query: 94 CDGEDDCRDGSDE--QHCEY--NILKSRFDGSNPSAPTTFV-------GHNGPE------ 136 C+G+DDCRD SDE Q C ++ + R S P ++ G N E Sbjct: 3813 CNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCG 3872 Query: 137 -----CHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRR----GHENMQSST---- 183 C RC G+CI VCDG CS G DE CT R GH T Sbjct: 3873 GTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAE 3932 Query: 184 -----------DFHDDVHLVDPT--------------------FFANEDNKCRSG----Y 208 + D++H D + F + DN C Sbjct: 3933 HKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMCDGDNDCGDNSDETS 3992 Query: 209 TMCHSGDVCIPXXXXXXXXXXXXXXXXE-----KNCQTNAPSEEEYLSGQADHMHSCSAA 263 + C S C P + +C N S+E H+ CS+ Sbjct: 3993 SECRSAQ-CDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE--------HLSMCSSF 4043 Query: 264 GMY-SCGTKGSEI--GVCIPMNATCNGIKECPLGDDE---SKHCSECARKR------CDH 311 Y C + + G C+ C+ +C DE SKH + + + C H Sbjct: 4044 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 4103 Query: 312 TCMNTPHGARCICQEGYKL-ADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYE 370 C + G C C++G++ C D DECA + + C C + GS+ C+C YE Sbjct: 4104 ICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGN-NTCTQLCLNTKGSYLCRCHEDYE 4162 Query: 371 LET-----DGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSN-YSAIQKFAGHGTI 424 G C+ + + +G + + L+ G+N ++A + I Sbjct: 4163 NNVVVGSMTGKDCRAKGDAAN-----VMIGADDSLVQLSLHGSGTNRHAAAKANDDDNDI 4217 Query: 425 RSIDFMHRNNKMFMSISDE---HGDPTGELSVSDNGLMRVLRENVIGV--SNVAVDWIGG 479 I F R M+ E + + S G + +GV + +AVD+ G Sbjct: 4218 IGIAFDPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTG 4277 Query: 480 NVFFTQKSPSPSAG--------------------ISICTMSGMFCRRVIEGKEQGQSYRG 519 N+F S + G I +C G + ++++ G Q + Sbjct: 4278 NLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPT--A 4335 Query: 520 LVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHD-VYFGD 578 L+ P G I + D+ + +I A+MDG+ +I++ + + P+++AID + + +Y+ D Sbjct: 4336 LITAPSAGRICYSDA-GLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVD 4394 Query: 579 VERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQ 638 + + ++ VNID ER V+ + H PY + F +YW S++L VQ+ Sbjct: 4395 PKYRRVDAVNIDGSERTTVVHDR-HIPYAVDVFENHIYWLSRESKTLYVQD-KFGRGRVS 4452 Query: 639 VIHTFNRYPYGIAVNHSLYQ-TGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTH 697 V+ + + + V+ + T + C +C LCV +P + F C+CPDG Sbjct: 4453 VLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGF----ACLCPDGIVP 4508 Query: 698 SVTENSCIPPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIV 757 + + SC H+ + M + C+ C NGG CR + Sbjct: 4509 QL-DGSC-------------ATQHVEALTMPKQCK----CTNGGKCRLDGS--------- 4541 Query: 758 CDCEGPYDGQYCER 771 C+C ++G CE+ Sbjct: 4542 CECTSDFEGDQCEK 4555
Score = 87.0 bits (214), Expect = 1e-15 Identities = 50/133 (37%), Positives = 64/133 (48%), Gaps = 19/133 (14%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDE-SGCSYAHHCSTSFMLCKNGLCVANEFKCD 95 EF C N CI + W+CD DC G DE + C+Y+ C F C N CV N +KCD Sbjct: 3104 EFRCSNQ--HCIHSTWECDGDNDCLDGSDEHANCTYS-SCQPDFFQCANHKCVPNSWKCD 3160 Query: 96 GEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLV 155 G DDC DGSDE+ C N + +C + +C SG+CI V Sbjct: 3161 GNDDCEDGSDEKDCPKN---------------SASAQKASKCSNGQFQCTSGECIDDAKV 3205 Query: 156 CDGHQDCSGGDDE 168 CD + DC+ DE Sbjct: 3206 CDRNFDCTDRSDE 3218
Score = 84.7 bits (208), Expect = 7e-15 Identities = 55/147 (37%), Positives = 69/147 (46%), Gaps = 22/147 (14%) Query: 26 AVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDES--GCSYAHHCSTSFMLCK 83 AV +C +F C + L CIPA W+CD DCD G DE GC+ CS+ C Sbjct: 1264 AVTAESC-TPDQFKCVSSGL-CIPASWKCDGQQDCDDGSDEPKFGCTSGRQCSSDQFKCG 1321 Query: 84 NGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLR 143 NG C+ N + CDGE+DC DGSDE S T+ N +C + Sbjct: 1322 NGRCILNNWLCDGENDCGDGSDES-------------SERGCKTSM---NARKCPFEHVA 1365 Query: 144 CRSGQ--CIQPDLVCDGHQDCSGGDDE 168 C + Q CI +CDG C GG DE Sbjct: 1366 CENDQETCIPLHQLCDGKTHCPGGTDE 1392
Score = 75.9 bits (185), Expect = 3e-12 Identities = 48/148 (32%), Positives = 65/148 (43%), Gaps = 28/148 (18%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLC 87 N++ C Q +F C + + +CI W CD DC G DE C+ + CKN C Sbjct: 178 NHTACFQY-QFRCAD-KTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRC 235 Query: 88 VANEFKCDGEDDCRDGSDEQHC-EYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR- 145 +F+CD DDC D SDE C EY C P + C Sbjct: 236 QPRKFRCDYYDDCGDNSDEDECGEY------------------------RCPPGKWNCPG 271 Query: 146 SGQCIQPDLVCDGHQDCSGGDDEVNCTR 173 +G CI +CDG +DC+ G DE C++ Sbjct: 272 TGHCIDQLKLCDGSKDCADGADEQQCSQ 299
Score = 72.0 bits (175), Expect = 3e-11 Identities = 82/344 (23%), Positives = 119/344 (34%), Gaps = 51/344 (14%) Query: 28 NNSTCD---QAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHH--CSTSFMLC 82 + TC+ ++F CG +CIP W CD DC G DE G S C C Sbjct: 3619 DQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQC 3678 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL 142 N C CDG DDC D SDEQ+C+ P F C P R Sbjct: 3679 TNHNCTRPFQICDGNDDCGDSSDEQNCD-----------KACDPWMFKCAATGRCIPRRF 3727 Query: 143 RCRSGQCI-----QPDLVC-DGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTF 196 C + D +C ++C+ + N + + + D + Sbjct: 3728 TCDGDDDCGDRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRCDNDDDCGDGSDETPE 3787 Query: 197 FANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADH 256 A + C+ G+T C S CIP + +C+ N+ +++ Sbjct: 3788 CAQIE--CKKGWTRCSSSYRCIP---------NWAFCNGQDDCRDNSDEDKQRCP----- 3831 Query: 257 MHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNT 316 +C G + C T G CIP C+ +C DE + C + Sbjct: 3832 --TCDDVGEFRCATSGK----CIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRC 3885 Query: 317 PHGARCICQEGYKLADDGLTCE---DEDECATHGHLCQHF-CED 356 G C G K+ D + C DE +C L H C+D Sbjct: 3886 NDGK---CIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDD 3926
Score = 67.0 bits (162), Expect = 1e-09 Identities = 82/329 (24%), Positives = 117/329 (35%), Gaps = 87/329 (26%) Query: 27 VNNSTCDQAKE------FDCGNGRLRCIPAEWQCDNVADCDKGRDES-GCSYAHHCSTSF 79 + S + AKE F CG+G CI CD+ DC DE+ C + Sbjct: 2781 LRGSNSEPAKECLPPYNFQCGDG--SCILLGATCDSKPDCADASDENPNYCNTRSCPEDY 2838 Query: 80 MLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHP 139 LC N C+ + KC+ DDC DGSDE C PSA C Sbjct: 2839 NLCTNRRCIDSAKKCNHIDDCGDGSDELDC-------------PSAVA---------CAE 2876 Query: 140 PRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFAN 199 C +G CI VCDGH DC D++V+ E++ + D Sbjct: 2877 GTFPCSNGHCINQTKVCDGHNDCH--DEQVS-----DESLATCPGLPID----------- 2918 Query: 200 EDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQ--ADHM 257 CR C + ++CI +C A + + Q A H Sbjct: 2919 ----CRGVKVRCPNTNICIQPADLCDGY---------DDCGDKADENQLFCMNQQCAQHY 2965 Query: 258 HSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHCSECARKR-CDHTCMN 315 C + G CIP C+G +C G DE+ +C++ A K+ C + Sbjct: 2966 VRCPS-------------GRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLF 3012 Query: 316 TPHGARCICQEGYKLADDGLTCEDEDECA 344 +CI + C+ ED+C Sbjct: 3013 QCDNLKCISR--------AFICDGEDDCG 3033
Score = 58.2 bits (139), Expect = 5e-07 Identities = 87/376 (23%), Positives = 150/376 (39%), Gaps = 38/376 (10%) Query: 343 CATHGHLCQHFC-EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVR-- 399 C+T+ C H C + +F CKC G +L+ G C +A + +L I V Sbjct: 1751 CSTNP--CSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDA----KPFLVIIQKTNVFGI 1804 Query: 400 QMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLM 459 +M A + + + +G G + + +MF+ H +++ +D+ + Sbjct: 1805 EMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQIT-TDSAIY 1863 Query: 460 R--VLRENVIGVSNVAV---------DWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVI 508 R V N + + AV DW G N+ K + I I G R VI Sbjct: 1864 RSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKI---TQTIEIIRTQGKQYRSVI 1920 Query: 509 EGKEQGQSY----RGLVVHPMRGLIIWID--SYQKYHRIMMANMDGSQVRILLDNKLEVP 562 +Q + + V +G + W+D ++ A +DGS ++ N L Sbjct: 1921 LSNDQSPTAVVTPVAIAVDADKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAEL 1980 Query: 563 SALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGS 622 +AID VYF + + I V D ++R V+S+G P +A++ L++AD Sbjct: 1981 DHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAF 2040 Query: 623 ESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPS-NPCL--ELECPWLCVIVP 679 +S++V + PQ H F + +A +L S +PC C +C+ + Sbjct: 2041 DSIEVATINGDSQPPQWTH-FKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPL- 2098 Query: 680 KSDFIMTAKCVCPDGY 695 C C +GY Sbjct: 2099 ---MFAQRTCTCANGY 2111
Score = 55.1 bits (131), Expect = 6e-06 Identities = 87/381 (22%), Positives = 122/381 (32%), Gaps = 134/381 (35%) Query: 21 TAQAPAVNNSTCDQ---------------------------------------------- 34 T+Q +N CDQ Sbjct: 2728 TSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSE 2787 Query: 35 -AKE------FDCGNGRLRCIPAEWQCDNVADCDKGRDES-GCSYAHHCSTSFMLCKNGL 86 AKE F CG+G CI CD+ DC DE+ C + LC N Sbjct: 2788 PAKECLPPYNFQCGDG--SCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRR 2845 Query: 87 CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRS 146 C+ + KC+ DDC DGSDE C PSA C C + Sbjct: 2846 CIDSAKKCNHIDDCGDGSDELDC-------------PSAVA---------CAEGTFPCSN 2883 Query: 147 GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRS 206 G CI VCDGH DC D++V+ E++ + D CR Sbjct: 2884 GHCINQTKVCDGHNDCH--DEQVS-----DESLATCPGLPID---------------CRG 2921 Query: 207 GYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQ--ADHMHSCSAAG 264 C + ++CI +C A + + Q A H C + Sbjct: 2922 VKVRCPNTNICIQPADLCDGY---------DDCGDKADENQLFCMNQQCAQHYVRCPS-- 2970 Query: 265 MYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHCSECARKR-CDHTCMNTPHGARC 322 G CIP C+G +C G DE+ +C++ A K+ C + +C Sbjct: 2971 -----------GRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKC 3019 Query: 323 ICQEGYKLADDGLTCEDEDEC 343 I + C+ ED+C Sbjct: 3020 ISR--------AFICDGEDDC 3032
Score = 51.6 bits (122), Expect = 5e-05 Identities = 59/286 (20%), Positives = 126/286 (44%), Gaps = 16/286 (5%) Query: 343 CATHGHLCQHFCEDRL-GSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 C + C H C + C CANGY ++ SCK E ++ ++ +V Sbjct: 2084 CHINNGNCDHICIPLMFAQRTCTCANGY-VKDGQTSCKL----FDESFVIVATKTKVIGY 2138 Query: 402 PLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRV 461 P+ + S A++ G +I +D+ + + ++++ + ++ ++ V Sbjct: 2139 PIDETQ--SKGVAMEPIGGL-SITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAV 2195 Query: 462 LRENV--IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRG 519 +R+++ + + ++A+DWI N++F + I + + G + + ++ K + S Sbjct: 2196 IRDSIGSLTIKSLAIDWINYNMYFINHD-AERTNIEVSKLDGTYRKILLTTKTETPS--S 2252 Query: 520 LVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDV 579 + V P+ + W D QK I + +DGS+ +++ + + P+ L +D +Y+ D Sbjct: 2253 IAVDPVSRYLYWADQGQK-PTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDA 2311 Query: 580 ERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL 625 + I RV +V S+ + +A +YW D E L Sbjct: 2312 KMDGIYRVRSTGGTPELVRSD-IASAAGVALHGQNMYWTDNRLEKL 2356
Score = 48.1 bits (113), Expect = 5e-04 Identities = 63/283 (22%), Positives = 120/283 (42%), Gaps = 56/283 (19%) Query: 363 CKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM----------PLAD-FTDGSN 411 C CA G G +C+ P+ Y+ S G ++ + PL D F + SN Sbjct: 2426 CSCARGV---LKGRTCE-----EPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISN 2477 Query: 412 YSAIQKFAGHGTIRSIDFMHRN----NKMFMSISDEHGDPTGELSVSDNGLMRVLRENVI 467 +Q F +R + F+ + N + S+++ +P S + +R Sbjct: 2478 ---LQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAE-NPRLVFGASKQPHAKEIRH--- 2530 Query: 468 GVSNVAVDWIGGNVFFTQKSPSP-----SAGISICTMSGMFCRRVIEGKEQGQSYRGLVV 522 +S++ +DW+ ++FT +AG + T++ G L + Sbjct: 2531 -ISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIA------------SGDWTYALAI 2577 Query: 523 HPMRGLIIWIDSYQKYH------RIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYF 576 P GL+ W DS K RI +N+ G ++++ + +P+A+A+D+ +Y+ Sbjct: 2578 DPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYW 2637 Query: 577 GDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWAD 619 DV R IE + D + R+V+ S + + ++ +LY +D Sbjct: 2638 ADVNRLNIEVADYDGQNRKVIASG--YRAKSLDIWDRWLYMSD 2678
Score = 41.2 bits (95), Expect = 0.080 Identities = 55/275 (20%), Positives = 115/275 (41%), Gaps = 25/275 (9%) Query: 442 DEHGDPTGELSVSDNGLMR----------VLRENVIGVSNVAVDWIGGNVFFTQKSPSPS 491 D HG+ + DN + R VL + G+ +++ DWI +++ + Sbjct: 762 DVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSL 821 Query: 492 AGISICTMSGMFCRRVIEGK--EQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGS 549 + I + ++ + + + +VVHP +GL+ + ++ + I ++DG Sbjct: 822 EVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRP-AAIYRCHIDGQ 880 Query: 550 QVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKE-RRVVISNGVHHPYDM 608 +++ + L PS +AID+ + + +GD + I ++ D K ++ I N + P + Sbjct: 881 NCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPI--PVAI 938 Query: 609 AYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGI-AVNHSLYQTGP-----P 662 N ++Y+ S++ + S +++ F I ++ +Q P Sbjct: 939 TIMNEYIYYVHQRPYSIRRVHKKNGGGS-KIVREFGADERSIFSLKACSHQNQPIPDDSR 997 Query: 663 SNPCLELECPWLCVIVPKSDFI--MTAKCVCPDGY 695 +PC +C LC P + AKC C G+ Sbjct: 998 EHPCRASQCTQLCFATPSESHPNELEAKCACRQGF 1032
>gi|21294119|gb|EAA06264.1| agCP13194 [Anopheles gambiae str. PEST] Length = 1858 Score = 208 bits (530), Expect = 2e-52 Identities = 180/682 (26%), Positives = 290/682 (42%), Gaps = 106/682 (15%) Query: 35 AKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKN-GLCVANEFK 93 A EF C NG CIPA C+++ DC G DESGC Y + + C++ C++ + Sbjct: 96 AHEFQCENG--ACIPAAGHCNDIQDCADGSDESGCDYFLCRAPFWYRCRHESTCISGSSR 153 Query: 94 CDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPD 153 CDG+ DC G DE++C+ N P H P C C CI D Sbjct: 154 CDGQRDCLGGDDEENCD-----------NYEVP-----HRAPLCSKAEFTCTDRACIPAD 197 Query: 154 LVCDGHQDCSGGDDE-VNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCH 212 LVCDG Q C G DE + C D+ F + +S + +C Sbjct: 198 LVCDGVQHCLDGSDETIGCI---------------DIAGKCKGFLCRNKHCLQSHHWVCD 242 Query: 213 SGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKG 272 D C S+EE+ + H G Y C Sbjct: 243 GLDDC------------------------GDGSDEEHCLSECTLEH-----GKYECANNH 273 Query: 273 SEIGVCIPMNATCNGIKECPLGDDESKHCS----ECARKRC-DHTCMNTPHGAR-CICQE 326 + C+ + CNG +C G DE C C C TC P G C+C Sbjct: 274 T----CVDVTQVCNGADDCGDGSDEGPGCKVPADGCKALHCAPQTCKVLPDGKPVCLCGV 329 Query: 327 GYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTP 386 G++ C D +ECA +G LC C + GSF C C + + L DG +C+ + T Sbjct: 330 GFRFEPSAGRCVDVNECARYG-LCSQGCINTPGSFRCTCIDQFHLMRDGRTCELSSGT-- 386 Query: 387 EGYLFISLGGEVRQM---PLADFTDGSNYSAIQKFAGHGT-IRSIDFMHRNNKMFMSISD 442 E + + V M L + S + A G+ + D H+ + S+ D Sbjct: 387 EALMLYTTQKAVGAMYLTSLHQYYVAKELSQVIGVAYDGSHVYWTDISHKTESIERSLED 446 Query: 443 EHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGM 502 SD +++L +I ++A+DW+ GN++F S S I++C+ G Sbjct: 447 G----------SDR--VQLLTAGLISPEDIALDWLTGNIYF---SDSGQMHIAVCSSDGY 491 Query: 503 FCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVP 562 CR +++ ++ RG+ + P G + + D + I A MDG++ ++++ + + P Sbjct: 492 HCRAIVQ--DELHKPRGIALLPQNGTLFYSD-WGNNAMIGRARMDGTEQQVVVSDGIHWP 548 Query: 563 SALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGS 622 + L +D+ +Y+ D + + IE ++ D +R VV+ + + HP+ +A FN LYW+DW + Sbjct: 549 NGLTLDWPNQRLYWIDAKLKRIESMHFDGTDRVVVLDDVLKHPFSIAVFNDRLYWSDWDT 608 Query: 623 ESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSD 682 +S++ + ++H +R + + V HS Q S+ C C LC++ + Sbjct: 609 KSIQSCDKFTGKMRQTLVH--DRMIFDVHVYHSSIQP-KVSHACANHTCTHLCLLTSNA- 664 Query: 683 FIMTAKCVCPDGYTHSVTENSC 704 T C CP G S ++SC Sbjct: 665 ---TYACACPQGMELSRDKHSC 683
Score = 159 bits (402), Expect = 2e-37 Identities = 185/698 (26%), Positives = 279/698 (39%), Gaps = 112/698 (16%) Query: 22 AQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHH------- 74 A N T +F C +G C+ A +CD V DC G DE C+ Sbjct: 1086 ANCEGYNRRTNCTRYQFSCADG--FCVDATARCDQVPDCPDGSDEQECAGVGGKGGVAAT 1143 Query: 75 -CSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHN 133 C+ C +G + CDG DDC DG+DE+HC I G+ + + N Sbjct: 1144 TCAAGMFRCNSG----HALVCDGNDDCGDGTDEEHCVGRI------GATAAQCSEQAIAN 1193 Query: 134 GPECHPPRLRC-RSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLV 192 G RC RSG C+ C+G +C G+DE C+ G Q S D + Sbjct: 1194 GTA-----YRCARSGACLPAAARCNGTAECPHGEDETGCSNCGLREFQCS-----DGQCI 1243 Query: 193 DPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSG 252 + + D C G E+NC A G Sbjct: 1244 RQEWRCDHDQDCDDG--------------------------SDERNCTAGA-------DG 1270 Query: 253 QADHMHSCSAA-GMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECAR---KR 308 H H+ + CG G CIP+ C+G ++C G DE C+ Sbjct: 1271 STAHTHAIDCGRDTFECGP-----GECIPVAKLCDGRRDCTNGHDEEGACASACTGGLGP 1325 Query: 309 CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANG 368 C C +P G+ C C EGY+LA D TC D +ECA G C C + GS+ C C +G Sbjct: 1326 CAQICQKSPAGSICACLEGYELAGDRKTCTDVNECA-RGQPCAQQCANVHGSYRCACHDG 1384 Query: 369 YELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSID 428 + L D SCK + P +L + +VRQ+ L + + G I ++D Sbjct: 1385 FMLRPDKASCK---SVGPAPHLLYTALDQVRQLTL---QQPPRIDTVLRANG-SRITALD 1437 Query: 429 FMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSP 488 R +++ + E+G E + N RVL NV +AVDW+ GNV+F + Sbjct: 1438 LDVRQRRLYYAA--ENGAALYEHDLRTNE-TRVL-ANVGRPDRLAVDWVAGNVYFADAT- 1492 Query: 489 SPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRG------LIIWIDSYQKYHRIM 542 PS + +C C RV Q + + V P+ L WI +Q H I+ Sbjct: 1493 EPS--LKVCHFGRGACARV-ASFSQRNYVKAVAVDPVNRYLFYALLFSWI--FQVPHTIV 1547 Query: 543 M-ANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG 601 A +DGS ++ ++ + + SALA+D +Y+ ++ + RV+ + +RV+ + Sbjct: 1548 YRARLDGS-LQEIVTKQAGIVSALAVDPQAQLLYYTELAGNTLRRVDYLGQGQRVLAEDQ 1606 Query: 602 ---VHHPYDMA-YFNGFLYWADWGSESL-KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSL 656 +H P ++ Y N L S+ + Q + P + N P G+ + Sbjct: 1607 PGLLHQPVQLSVYENQALVVNRAPPGSIGQCQLYGQYRCEP---YRVNVPPTGLLLVVQE 1663 Query: 657 YQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDG 694 + N C C LCV V A+C+C +G Sbjct: 1664 SRQPMVPNVCDRANCTHLCVAVGP-----VARCICENG 1696
Score = 41.6 bits (96), Expect = 0.056 Identities = 29/78 (37%), Positives = 36/78 (46%), Gaps = 10/78 (12%) Query: 34 QAKEFDCGNGRLRCIPA-EWQCDNVADCDKGRDE----SGCSYAHHCSTSFMLCKNGLCV 88 + K F C N C+ + W CD + DC G DE S C+ H + N CV Sbjct: 222 KCKGFLCRNK--HCLQSHHWVCDGLDDCGDGSDEEHCLSECTLEH---GKYECANNHTCV 276 Query: 89 ANEFKCDGEDDCRDGSDE 106 C+G DDC DGSDE Sbjct: 277 DVTQVCNGADDCGDGSDE 294
Score = 37.7 bits (86), Expect = 0.78 Identities = 73/367 (19%), Positives = 141/367 (38%), Gaps = 26/367 (7%) Query: 344 ATHGHLCQHFC-EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMP 402 A H C H C ++AC C G EL D HSC A+ + + +G + + Sbjct: 648 ACANHTCTHLCLLTSNATYACACPQGMELSRDKHSC---ASVAKRQDILLGIGHYLVTIK 704 Query: 403 LADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVL 462 F G + + + TI + F ++F++ + T EL R++ Sbjct: 705 HHPF--GRHATGRGEPLPVATISRLAFNSLTGELFVADNSRRAIYTVELGSLRT--QRLV 760 Query: 463 RENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVV 522 R + ++ +A D++ ++++ S S+ T R +I+ + L + Sbjct: 761 RSGIGRITALAFDYLSNTLYWSDAERSTIEIYSLQTRH----RSIIQHYLGDDAPVALAL 816 Query: 523 HPMRG-LIIWIDSYQKYHRIMMANMDGSQVRI-LLDNKLEVPS--ALAIDYIRHDVYFGD 578 P G + + + S + I +M G +++ +L + A+D V++ D Sbjct: 817 IPETGKMFVALRSPSGHTHIDRQDMTGRGPHTHVIEERLGSNGTISFAVDQDLRSVFWSD 876 Query: 579 VERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQ 638 IE + + R + + P +A L+W GS+ L + + ++ + Sbjct: 877 SGTNRIEITSFEGDTRH-LFREYLREPVSLAIIGSELFWTCRGSQRLYWSDKHNVGATKR 935 Query: 639 VIHTFN---RYPYGIAVNHSLYQTGPPSNPCLELE--CPWLCVIVPKSDFIMTAKCVCPD 693 + P + + S T P +PC C +CV + + T+ CVCP Sbjct: 936 ISVQLPPDLAVPDEMPIAASQPTTRRPDHPCTRSNGGCSHICV----AGGLYTSACVCPT 991 Query: 694 GYTHSVT 700 G + T Sbjct: 992 GMVFNTT 998
>gi|21291536|gb|EAA03681.1| agCP14677 [Anopheles gambiae str. PEST] Length = 738 Score = 208 bits (529), Expect = 4e-52 Identities = 184/689 (26%), Positives = 293/689 (42%), Gaps = 113/689 (16%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLC 87 ++ TC ++ EF CGNG RCI W CD+ DC DE C C C Sbjct: 1 SDETC-RSDEFTCGNG--RCIQKRWVCDHDDDCGDKTDEDNCPTTTCDPLKQFACAENYC 57 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 + ++++CDGE DC DGSDE+ C +NP PT C P +C Sbjct: 58 ITSKWRCDGEPDCPDGSDERGC-----------ANPPPPTF------STCLPLEYQCNDR 100 Query: 148 -QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRS 206 CI +CDG +DC GDDE+ P N CRS Sbjct: 101 ITCIHRSWICDGEKDCPRGDDEM------------------------PPICQNV--TCRS 134 Query: 207 GYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMY 266 C CI E+NC N SE+ C+ + Sbjct: 135 DQFQCKKDKTCINGHFACNGKNDCSDGSDEQNCGVNVRSEK------------CNPKTEF 182 Query: 267 SCGTKGSEIGVCIPMNATCNGIKECP-LGDDESKHC--SECARKR--CDHTCMNTPHGAR 321 CG G+CIP+ C+ +CP D+ + C +EC + C C++TP G Sbjct: 183 DCGG-----GMCIPLAKVCDQNPDCPEFQDEPADKCGKNECLQGNGGCSQLCVDTPAGFY 237 Query: 322 CICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHS-CKY 380 C C+ G+KLAD+ TC D DEC G C C + +G+F C+C + Y + H+ CK Sbjct: 238 CDCKPGFKLADN-RTCVDIDECEEPGS-CSQSCINEIGTFKCECMDNYLRDPRDHTRCK- 294 Query: 381 EATTTPEGY--LFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFM 438 EG+ L + ++R++ L D ++I T ++DF+ R ++ Sbjct: 295 ----PKEGHASLLFARRHDIRKISL----DHREMTSIVNDTKSAT--ALDFVFRTGMIYW 344 Query: 439 SISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICT 498 S E + + + V+++ ++ +AVDWI +++FT S I + Sbjct: 345 SDVSEKRIYKAPIDEGSDKTV-VVKDQLVTSDGLAVDWIYNHIYFTDIKKST---IELTN 400 Query: 499 MSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNK 558 G + +I+ + + R + + P+ G + W D + RI A MDG+ ++++ + Sbjct: 401 FDGNMGKVLIQ--DDLEIPRAIALDPIDGWMYWTD-WGTNPRIERAGMDGTHRQVIVSYE 457 Query: 559 LEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI--SNGVHHPYDMAYFNGFLY 616 ++ P+ + +D +R VY+ D + +I N D +R V++ ++ + HP+ + F ++Y Sbjct: 458 VKWPNGITLDLVRKRVYWVDAKLNVISSCNYDGSKRSVILYSADYLRHPFSITTFEDYVY 517 Query: 617 WADWGSESL---------KVQEMTHHH--SSPQVIHTFNRYPYGIAVNHSLYQTGPPSNP 665 W DW E++ V+ +T H P IH ++ Y VNH G S+ Sbjct: 518 WTDWDKEAVFKANKFTGKDVEPVTAMHMLQHPMTIHVYHPYRQPDGVNHCQAVNGHCSHL 577 Query: 666 CLELECPWLCVIVPKSDFIMTAKCVCPDG 694 C L P + PK C CP G Sbjct: 578 C--LPAPQINANSPK------ISCACPTG 598
Score = 72.0 bits (175), Expect = 4e-11 Identities = 51/152 (33%), Positives = 64/152 (42%), Gaps = 22/152 (14%) Query: 19 KNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESG--CSYAHHCS 76 + A P STC E+ C N R+ CI W CD DC +G DE C S Sbjct: 77 RGCANPPPPTFSTC-LPLEYQC-NDRITCIHRSWICDGEKDCPRGDDEMPPICQNVTCRS 134 Query: 77 TSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPE 136 F K+ C+ F C+G++DC DGSDEQ+C N+ R + NP Sbjct: 135 DQFQCKKDKTCINGHFACNGKNDCSDGSDEQNCGVNV---RSEKCNPKT----------- 180 Query: 137 CHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDE 168 C G CI VCD + DC DE Sbjct: 181 ----EFDCGGGMCIPLAKVCDQNPDCPEFQDE 208
>gi|21294378|gb|EAA06523.1| agCP13610 [Anopheles gambiae str. PEST] Length = 1768 Score = 207 bits (528), Expect = 4e-52 Identities = 192/728 (26%), Positives = 296/728 (40%), Gaps = 125/728 (17%) Query: 47 CIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDE 106 CI +W CD DC DE+ C H C+ C+NG+C+ ++ CDG++DC D SDE Sbjct: 63 CISRDWLCDGDDDCGDYTDETHCGNRHDCTEEKFECQNGMCIPRDWVCDGDNDCNDLSDE 122 Query: 107 QHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGD 166 ++C +C RC+ G CI CDG DC Sbjct: 123 KNCT------------------------KQCTRDEFRCKDGSCISASFQCDGETDCIDES 158 Query: 167 DEVNCTRRGHENMQSSTD------------FHDDVHLVDPTFFANEDNKCRS-------- 206 DE NC R MQS + V F + DN C Sbjct: 159 DEANCDR----PMQSCPEGEFKCKGALGGMGGPGGRCVLMRFRCDGDNDCGDWSDEENCA 214 Query: 207 --------GYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC-------QTNAPSEEEYLS 251 C GD CIP EKNC +T +P E Sbjct: 215 KKQVDCMINEFKCDDGD-CIPLQWRCDDKQDCNNGEDEKNCPVDRIAGRTCSPDEYTCKD 273 Query: 252 GQADHMHSCSAAGMYSC----------------------GTKGS--EIGVCIPMNATCNG 287 G+ + S G C G++ S + VCI C+G Sbjct: 274 GRCI-LRSWVCDGSADCRRGEDEQDCDIKCELNQFLCPSGSRNSTRDSSVCINQKHVCDG 332 Query: 288 IKECPLGDDESKH--CSEC-ARKRCDHTCMNTPHG-ARCICQEGYKLADDGLTCEDEDEC 343 +C G+DE + C A RC+ C+ G C+C+ GY L +G C D DEC Sbjct: 333 HTDCANGEDEMRCPIVHPCGAHSRCEQLCITAYSGREECMCRPGYLLHGNGYNCTDIDEC 392 Query: 344 A-THGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMP 402 + T +C C + GSF C C GY L D +CK + L ++ ++RQ+ Sbjct: 393 SITSNPVCSQECLNVAGSFRCSCQPGYVLRPDQRTCKAVGGSVK---LLMANRADIRQVS 449 Query: 403 LADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVL 462 L++ + Y++I K G ++D+ +R + +F +D D ++ +G+ V+ Sbjct: 450 LSN----NQYTSIAK--GLPNAIALDYHYRQDLLFW--TDVSIDVIKRSHLNGSGVRDVI 501 Query: 463 RENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVV 522 + + +AVDWI +F+T S + + + T+ G R VI + + R + V Sbjct: 502 KWGLESPGGLAVDWIHDLLFWTD---SGTRRVEVSTLDGQM-RAVIAASDLDKP-RAIAV 556 Query: 523 HPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQ 582 HP R L+ W D + +I A MDGS + ++ + P+ L IDY +Y+ D + Sbjct: 557 HPGRALVFWTD-WGTAPKIERAFMDGSDRQTIIAEAIFWPNGLTIDYTSSRIYWADA-KH 614 Query: 583 LIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHT 642 +IE N D + RR ++SN + HP+ +A F +YW DW ++++ + +V+H Sbjct: 615 VIESANFDGRARRKILSNNLPHPFALALFEDSMYWTDWHTKTISTASKVNGRGF-RVVHE 673 Query: 643 FNRYPYGIAVNHSLYQTGPPSNPCLELE------CPWLCVIVPKSDFIMTAKCVCPDGYT 696 +P GI H Q +N C + C LC+ +C CP G T Sbjct: 674 GLHFPMGIQSYHPSRQPD-FTNRCAADKNGRKGGCSHLCLPARTH-----RRCACPIGLT 727 Query: 697 HSVTENSC 704 + +C Sbjct: 728 LRPDQKTC 735
Score = 99.0 bits (245), Expect = 3e-19 Identities = 88/348 (25%), Positives = 150/348 (43%), Gaps = 27/348 (7%) Query: 350 CQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDG 409 C H C C C G L D +C +T P+ L I+ +VR L D Sbjct: 707 CSHLCLPARTHRRCACPIGLTLRPDQKTC----STVPDKLLLIARKKDVRVRQL----DA 758 Query: 410 SN-YSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIG 468 +N + G + ++D+ R N ++ +D ++ + +++ N+I Sbjct: 759 ANPVDMVLPLDGIKSTVAVDWCSRTNVIYW--TDVGKSMISRAFINGSQQEAIVKANLIS 816 Query: 469 VSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGL 528 + +A+DW+ +++T + I T G +R + E+ R +VVHP G Sbjct: 817 PAGLALDWVTDKIYWTDPG---TNRIEAATTDGR--QRALLIWERLDKPRDIVVHPGEGY 871 Query: 529 IIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVN 588 + W D + I A MDG+ L+ L+ P+ LA+D + +YF D + +E VN Sbjct: 872 MFWSD-WGSNPLIERAGMDGTGRFTLVSENLQWPNGLALDVDKQRLYFLDGGTKSLEYVN 930 Query: 589 IDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPY 648 D R +I+ G+ HP+ + + +YW DW + S++V M + H ++ N Sbjct: 931 YDGTGRNRLITEGLKHPFGLDVYEKRVYWTDWDTHSIQVANMYNGHDRRTILAN-NTDLM 989 Query: 649 GIAVNHSLYQTGPPSNPCLELE--CPWLCVIVPKSDFIMTAKCVCPDG 694 I V H + NPC C ++C++ P S C CP G Sbjct: 990 DIRVFHRNRRDS--RNPCAHKNGGCSYICLLNPTS-----YSCACPIG 1030
Score = 93.2 bits (230), Expect = 2e-17 Identities = 81/303 (26%), Positives = 147/303 (48%), Gaps = 21/303 (6%) Query: 340 EDECATHGHLCQHFCEDRLGSFACKCANGYEL-ETDGHSCKYEATTTPEGYLFISLGGEV 398 E+ C C H C ++CKC G + E CK T P+ YL I+L + Sbjct: 1307 ENVCGAGNGGCSHLCLRNPTGYSCKCPTGLTMREGSTTDCK----TLPDEYLLIALRSGI 1362 Query: 399 RQMPLADFTDGSNYSAIQKFAG-HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNG 457 ++ L D D + + G HG + +D+ + M++ +D + D +++ + Sbjct: 1363 GRISL-DTPD--LFDVVLPIEGVHGAV-VLDYHF--DSMYVFYADVNVDAIRRVNMHNYS 1416 Query: 458 LMRVLRENVIGVSN-VAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQS 516 +V+ + + N +AVDW+ N+++T + I + + G CR+ I + Sbjct: 1417 DTQVIVSSGLNTPNGIAVDWLADNLYWTDTALKK---IEVARLDGS-CRKAIL-TDGLDD 1471 Query: 517 YRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYF 576 R ++++P RG + W D + + +I A MDGS+ R ++D +L P+ LAID+ +Y+ Sbjct: 1472 PRSIILYPKRGFVFWAD-WGQTPKIERAYMDGSERRSIVDFELGFPTGLAIDFDAKKLYW 1530 Query: 577 GDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSS 636 D + IE + D + R+ V+S+ HP+ LYW DW ++S+ ++ H SS Sbjct: 1531 ADALQDRIELCDFDGRRRQQVVSHAT-HPFGFTLTATHLYWTDWYNKSV-LRAPKHSVSS 1588 Query: 637 PQV 639 +V Sbjct: 1589 VEV 1591
Score = 75.5 bits (184), Expect = 4e-12 Identities = 71/292 (24%), Positives = 129/292 (44%), Gaps = 24/292 (8%) Query: 338 EDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGE 397 + + CA C + C S++C C G +L+ +G +CK + P YL + E Sbjct: 1000 DSRNPCAHKNGGCSYICLLNPTSYSCACPIGIQLKDNGKTCK----SGPSNYLVFAHRTE 1055 Query: 398 VRQMPLADFTDGSNYS--AIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSD 455 VRQ+ L S+Y + + ++D R +++ + + E D + Sbjct: 1056 VRQVSL-----DSDYQIDVVLPLPPISNVVTLDVDRRTGEIYWADTIE--DVIMRSTPDG 1108 Query: 456 NGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGM--FCRRVIEGKEQ 513 + ++ E++ V + +D IG +++T AG + +S + R + K+ Sbjct: 1109 MRIKQIYSESMTSVDGLVIDSIGRKLYWT------DAGRKVLEVSDLEEGIRSALVWKDL 1162 Query: 514 GQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHD 573 Q RG+ + G + W D + RI A+MDG L+ L P+ LA+D Sbjct: 1163 EQP-RGIALDYESGYLFWSD-WGANPRIERADMDGENRVDLITEGLGWPNGLAVDRAAKR 1220 Query: 574 VYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL 625 +Y+ D + + IE + R V+ N + HPY +A +YW DW +++L Sbjct: 1221 IYWADAQMKTIESCTLSGGARTKVVEN-LPHPYALAVTGRTIYWTDWITKAL 1271
>gi|7511796|pir||T18308 probable vitellogenin receptor - yellow fever mosquito gi|3386583|gb|AAC28497.1| putative vitellogenin receptor [Aedes aegypti] gi|13273500|gb|AAK15810.1| vitellogenin receptor [Aedes aegypti] Length = 1847 Score = 206 bits (525), Expect = 1e-51 Identities = 180/689 (26%), Positives = 288/689 (41%), Gaps = 104/689 (15%) Query: 22 AQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFML 81 A+APA + E+ C NG CIP C+ DC G DE GC Y + Sbjct: 40 AKAPACAEN------EYRCDNG--ACIPDVNHCNGAKDCTDGSDEVGCDYFLCKKPMWYR 91 Query: 82 CK-NGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPP 140 CK + C++ F CD DDC G DE++CE N P H C Sbjct: 92 CKHDKSCISATFLCDKHDDCPLGDDEENCE-----------NFEVP-----HVPVPCSKF 135 Query: 141 RLRCRSGQCIQPDLVCDGHQDCSGGDDE-VNCTRRGHENMQSSTDFHDDVHLVDPTFFAN 199 C CI DLVCDG C G DE + C + Sbjct: 136 EFTCTDKMCIPLDLVCDGVSHCLDGSDETIGCK--------------------------D 169 Query: 200 EDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHS 259 +NKC+ G VC +C + E ++ +H Sbjct: 170 IENKCK--------GFVC---KNKRCINSHDWVCDGIDDCGDGSDEENCFIGCDLEH--- 215 Query: 260 CSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCS--ECARKRCDHTCMNTP 317 G + C + C+ + C+G +C DE C+ EC RC C TP Sbjct: 216 ----GKFECADNST----CVDLKLVCDGKDDCGDHSDEGGSCNSKECDSMRCPEGCKATP 267 Query: 318 HGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHS 377 HGA C+C+ G++ CED +EC +G LC CE+ GSF C C + ++L+ D + Sbjct: 268 HGAVCLCKPGFRFNKKSKVCEDINECERYG-LCSQGCENTPGSFKCTCVDKFKLKDDSRT 326 Query: 378 CKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMF 437 C+ + +T P L + + + L T Y A G ++ + F Sbjct: 327 CELDDSTEP--LLLYTTQKSIGGLHLN--TKHQYYVAKDLSQVIGVSYDGRHVYWTDISF 382 Query: 438 MSISDEHGDPTGELSVSDNGLMR--VLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGIS 495 + S E ++G R +L + ++ +DW+ GN++F S S I+ Sbjct: 383 KTESIERS--------LEDGTKRELLLTSGLASPEDLEIDWLTGNIYF---SDSGHMMIA 431 Query: 496 ICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILL 555 +C+ +G+ C +I+ + RG+ + P G + + D + I A MDG RIL+ Sbjct: 432 VCSNNGVHCTILIQ--DTLHKPRGIALMPQNGTLFYSD-WGDNAMIGAAGMDGKNKRILI 488 Query: 556 DNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFL 615 + + P+ L +D+ +Y+ D + + IE + +D R V+++ + HP+ +A FN L Sbjct: 489 EQDIHWPNGLCLDWPNGRLYWVDAKLKKIESIRVDGTNRVTVLADVLKHPFSIAVFNDRL 548 Query: 616 YWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLC 675 YW+DW ++S++ + + V+H +R + + + HS Q +PCL C LC Sbjct: 549 YWSDWDTKSIQSCDKFNGKDRKIVVH--DRQIFDVHIYHSGLQP-KGDHPCLGTFCSHLC 605 Query: 676 VIVPKSDFIMTAKCVCPDGYTHSVTENSC 704 ++ P + C CP G + ++SC Sbjct: 606 LLAPNDSY----SCACPYGMSLKADKHSC 630
Score = 188 bits (478), Expect = 3e-46 Identities = 167/584 (28%), Positives = 252/584 (43%), Gaps = 93/584 (15%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDE-SGCSYAHHCSTSFMLCKNGL 86 N +TC F C G +CIP W+CD DC G DE C C F C G Sbjct: 1085 NATTCGPLM-FRCNMG--QCIPKWWECDGNPDCTDGSDEHDKCLTKTDCGAGFTKCALGH 1141 Query: 87 CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRS 146 C+ + CDG +DC D SDE +C+ + G PT + L RS Sbjct: 1142 CIEDRLLCDGNNDCGDNSDELNCKVELEPCV--GLEDDNPTKY------------LCPRS 1187 Query: 147 GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRS 206 G+C+ + C+G +C G+DE C+ G + Q C+S Sbjct: 1188 GKCLDIAVRCNGTAECPDGEDEAGCSNCGLQEFQ-----------------------CKS 1224 Query: 207 GYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMY 266 G CI E +C +E +H G + Sbjct: 1225 GK--------CIRKEWRCDKEVDCDDGSDEVDCVNGTAAEHL-------EVHVACGEGTF 1269 Query: 267 SCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSE-CARKRCDHTCMNTPHGARCICQ 325 C + GVCI M+ CNG K+C G DE K C + CA+ C+H C+ TP GA C C+ Sbjct: 1270 EC-----KPGVCIEMSQVCNGKKDCDDGKDEGKGCDDACAKSPCEHKCIKTPTGAICECR 1324 Query: 326 EGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTT 385 EG+ LA + +C D DECA G C C + GS+ C C G+ L +D SCK Sbjct: 1325 EGFTLAPNKKSCLDVDECA-EGRPCAQQCRNTFGSYRCSCNPGFMLRSDKISCK---AVG 1380 Query: 386 PEGYLFISLGGEVRQMPLADFTDGSNYSAIQKF--AGHGTIRSIDFMHRNNKMFMSISDE 443 P Y+ + ++R++ + N +I+ A I S+D R ++ +DE Sbjct: 1381 PSRYVLYTSYNQIRKLEV-------NPPSIRILMQANGSRITSMDVDIRRQMLYF--TDE 1431 Query: 444 HGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMF 503 + E + N + NV ++AVDWI GNV+F +S PS I +C++ Sbjct: 1432 YNPVIYEHDMERNTTHVLY--NVGHPEHLAVDWITGNVYFYDRS-EPS--IKLCSVQRQL 1486 Query: 504 CRRVIEGKEQGQSYRGLVVHPMRGLI------IWIDSYQKYHRIMM-ANMDGSQVRILLD 556 C R+I Q + +VV P+ ++ WI +Q H I+ A+MDG Q ++++ Sbjct: 1487 CSRIITFASQ-VFVKAVVVDPVNRILFYSLMHFWI--FQVPHSIIYRADMDG-QNQLVIT 1542 Query: 557 NKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 + ++L +D +Y D+ + I ++ + K+ R VI N Sbjct: 1543 KDVSHVTSLQVDTENKLLYIADISSRTINALDYEGKKLRTVIEN 1586
Score = 59.7 bits (143), Expect = 2e-07 Identities = 49/155 (31%), Positives = 67/155 (43%), Gaps = 26/155 (16%) Query: 12 LFIHILIKNTAQAP-AVNNSTCDQA--KEFDCGNGRLRCIPAEWQCDNVADCDKGRDESG 68 L I + TA+ P + + C +EF C +G +CI EW+CD DCD G DE Sbjct: 1191 LDIAVRCNGTAECPDGEDEAGCSNCGLQEFQCKSG--KCIRKEWRCDKEVDCDDGSDEVD 1248 Query: 69 C---SYAHH------CSTSFMLCKNGLCVANEFKCDGEDDCRDGSDE-QHCEYNILKSRF 118 C + A H C CK G+C+ C+G+ DC DG DE + C+ KS Sbjct: 1249 CVNGTAAEHLEVHVACGEGTFECKPGVCIEMSQVCNGKKDCDDGKDEGKGCDDACAKSPC 1308 Query: 119 DGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPD 153 + PT G C CR G + P+ Sbjct: 1309 EHKCIKTPT------GAIC-----ECREGFTLAPN 1332
Score = 37.0 bits (84), Expect = 1.6 Identities = 83/396 (20%), Positives = 153/396 (38%), Gaps = 43/396 (10%) Query: 334 GLTCEDEDECATHGHLCQHFCEDRLG-SFACKCANGYELETDGHSCKYEATTTPEGYLFI 392 GL + + C G C H C S++C C G L+ D HSC+ T YL + Sbjct: 587 GLQPKGDHPCL--GTFCSHLCLLAPNDSYSCACPYGMSLKADKHSCR---ETVKRQYLLV 641 Query: 393 SLGGEVRQMPLADFT--DGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGE 450 + + + F + S A Q F SI ++F ++D Sbjct: 642 GIANYLVTLETQTFGRHESSQADAYQIFFHRMAFNSI-----TGEIF--VADNRQKAIFT 694 Query: 451 LSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEG 510 + +++ + +S +A D++G N+++T S S+ T R I Sbjct: 695 VDPKTKSSQKLITTGIGNISALAFDFLGNNLYWTDSERSTVEVFSLQTR-----HRAILQ 749 Query: 511 KEQGQSYR-GL-VVHPMRGLIIWIDSYQKYHRIMMANMD----GSQVRILLDNKLEVPSA 564 GQ GL +V M + I + S + +D G + + ++ +L + Sbjct: 750 HYLGQDIPVGLAIVSEMGKMFIALRSPLPVPHTHIDRLDMTGRGPHLHV-IEERLSGNGS 808 Query: 565 --LAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGS 622 ID VY+ D+ IE + + R + + P +A ++W + S Sbjct: 809 FNFVIDRDLRTVYWNDMGSSKIEFTSYEGDTRH-LFREFLRLPVSIAIVGDSIFWTCYRS 867 Query: 623 ESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPP----SNPCLELE--CPWLCV 676 + L + + + ++ T ++ PYG + + P +PC++ C +C Sbjct: 868 KRLYWSDKHNLGVTKKI--TIDKPPYGAFPDEIVLLGSQPLQRYDHPCMKQNGGCSHIC- 924 Query: 677 IVPKSDFIMTAKCVCPDGYTHSVTEN-SCIPPVTIE 711 VP + ++ C+CP G S +N +CI + E Sbjct: 925 -VPAG--MYSSACICPTGMIFSSPKNTTCIDAIDCE 957
>gi|14718545|gb|AAK72954.1|AF355595_1 lipophorin receptor [Aedes aegypti] Length = 1156 Score = 204 bits (518), Expect = 7e-51 Identities = 181/686 (26%), Positives = 284/686 (41%), Gaps = 111/686 (16%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCV 88 N TC ++ EF C NG RCI WQCD DC DE GC C C+ Sbjct: 211 NETC-RSDEFTCANG--RCIQKRWQCDRDDDCGDNSDEKGCQATTCDPLKQFACSENYCI 267 Query: 89 ANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG- 147 ++++CDGE DC DGSDE+ C +NP+ PT C +C Sbjct: 268 TSKWRCDGEPDCPDGSDERGC-----------TNPTPPTV------NPCLSLEYQCSDRI 310 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSG 207 CI +CDG +DC GDDE+ P N CR Sbjct: 311 TCIHKSWICDGEKDCPQGDDEM------------------------PPICQNV--TCRPD 344 Query: 208 YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYS 267 C CI E +C+ A C+ + Sbjct: 345 QFQCKKDKTCINGHFHCNGKPECSDGSDEVDCERPAV--------------KCNPKTEFD 390 Query: 268 CGTKGSEIGVCIPMNATCNGIKECP-LGDDESKHC--SECARKR--CDHTCMNTPHGARC 322 CG G+CIP++ C+ +CP D+ + C +EC C H C++TP G C Sbjct: 391 CGG-----GMCIPLSKVCDKKPDCPEFQDEPNDKCGKNECLENNGGCSHLCVDTPAGFYC 445 Query: 323 ICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHS-CKYE 381 C+ GYKL ++ TCED DECA G C C + +G+ C+C GY + H+ CK Sbjct: 446 DCKPGYKLVNN-RTCEDIDECAEAGS-CSQKCTNEIGTSKCECMPGYLRDPRDHTKCK-- 501 Query: 382 ATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSIS 441 T L + ++R++ L D ++I T ++DF+ R ++ S Sbjct: 502 -ATEGHASLLFARRHDIRKISL----DHREMTSIVNDTKSAT--ALDFVFRTGMIYWSDV 554 Query: 442 DEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSG 501 E + + + V+++ + +AVDWI +++FT A I + G Sbjct: 555 SEQRIYKAPIDEGSDKTV-VVKDQTVTSDGLAVDWIYNHIYFTDIK---KATIELTNFDG 610 Query: 502 MFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEV 561 + +I K+ + R + + P+ G + W D + RI A MDG+ ++++ +++ Sbjct: 611 NMGKILI--KDDLEIPRAIALDPIDGWMYWTD-WGTTPRIERAGMDGTHRQVIVTYEVKW 667 Query: 562 PSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI--SNGVHHPYDMAYFNGFLYWAD 619 P+ + +D +R VY+ D + I + D +R VV+ ++ + HP+ + F ++YW D Sbjct: 668 PNGITLDLVRKRVYWVDAKLNTISSCDYDGSKRTVVLYSADYLRHPFSITTFEDYVYWTD 727 Query: 620 WGSESL---------KVQEMTHHH--SSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLE 668 W E++ ++ +T H P IH ++ Y NH G S+ C Sbjct: 728 WDKEAVFKASKFNGKDIEPVTAMHMLQHPMTIHVYHPYRQPDGTNHCQAVNGHCSHLC-- 785 Query: 669 LECPWLCVIVPKSDFIMTAKCVCPDG 694 L P + PK C CP G Sbjct: 786 LPAPQINSRSPK------ISCACPTG 805
>gi|4235639|gb|AAD13300.1| low density lipoprotein receptor [Sus scrofa] Length = 782 Score = 202 bits (513), Expect = 2e-50 Identities = 184/710 (25%), Positives = 292/710 (41%), Gaps = 108/710 (15%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F CG RCIP W+CD DC+ G DE GCS CS C++G C+A +F CD Sbjct: 22 DFSCGGRVNRCIPESWRCDGQQDCENGSDEEGCS-PKTCSQDEFRCQDGKCIAPKFVCDS 80 Query: 97 EDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVC 156 + DC DGSDE C PT P C P +C S CI C Sbjct: 81 DRDCLDGSDEASC----------------PT-------PTCGPASFQCNSSTCIPELWAC 117 Query: 157 DGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDV 216 DG DC G DE R H + + +N C + CHSG+ Sbjct: 118 DGDPDCEDGSDEWPQHCRSHSS----------------SLPERSNNPCSALEFHCHSGE- 160 Query: 217 CIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGM-YSCGTKGSEI 275 CI E+NC +E+ +H Y C E Sbjct: 161 CIHSSWRCDGDTDCKDKSDEENCDVATCRPDEFQCSDGTCIHGSRQCDREYDCKDLSDEQ 220 Query: 276 GV------------------CIPMNATCNGIKECPLGDDES-KHC--SECARKR--CDHT 312 G CI ++ CN +++C DE K C +EC + C H Sbjct: 221 GCVNVTLCEGPNKFKCQSGECISLDKVCNSVRDCRDWSDEPLKECGTNECLDNKGGCSHI 280 Query: 313 CMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELE 372 C + G C+C EG++L D CED DEC C C + GS+ C+C G++LE Sbjct: 281 CNDLKIGYECLCPEGFQLVDKH-RCEDIDEC-QDPDACSQICVNLEGSYKCQCEEGFQLE 338 Query: 373 TDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHR 432 +CK T YLF + EVR+M L D S Y+++ + ++D Sbjct: 339 PLTKACKAIGTI---AYLFFTNRHEVRKMTL----DRSEYTSL--IPNLKNVVALDTEVA 389 Query: 433 NNKMFMSISDEHGDPTGEL--SVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSP 490 +N+++ S + + ++ + S + ++ E++ +AVDWI N+++T S Sbjct: 390 SNRIYWSDLSQRKIYSTQINRAPSFSSYDTIIGEDLQAPDGLAVDWIHSNIYWTD---SI 446 Query: 491 SAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQ 550 +S+ G+ +R +E+G R +VV P+ G + W D + +I ++G Sbjct: 447 LGTVSVADTKGV--KRKTLFQEKGSKPRAIVVDPVHGFMYWTD-WGTPAKIKKGGLNGVD 503 Query: 551 VRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH--HPYDM 608 V L+ ++ P+ + +D +Y+ D + I ++++ R+ V+ + HP+ + Sbjct: 504 VYSLVTEDIQWPNGITLDLSGGRLYWVDSKLHSISSIDVNGGNRKTVLEDKTKLAHPFSL 563 Query: 609 AYFNGFLYWADWGSESL---------KVQEMTHHHSSPQVIHTFNRYPYGIAVN---HSL 656 A F ++W D +E++ + M + SP+ I F+ VN + Sbjct: 564 AIFEDKVFWTDVINEAIFSANRLTGSDIHLMAENLLSPEDIVLFHNLTQPRGVNWCERTA 623 Query: 657 YQTGPPSNPCLELECPWLCVIVPKSDFIMTA-KCVCPDGYTHSVTENSCI 705 Q G C +LC+ P+ + C CPDG + SC+ Sbjct: 624 LQNG---------GCQYLCLPAPQINPRSPKFTCACPDGMLLAKDMRSCL 664
>gi|3153895|gb|AAC17444.1| low density lipoprotein receptor [Sus scrofa] Length = 801 Score = 202 bits (513), Expect = 2e-50 Identities = 187/714 (26%), Positives = 289/714 (40%), Gaps = 116/714 (16%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F CG RCIP W+CD DC+ G DE GCS CS C++G C+A +F CD Sbjct: 41 DFSCGGRVNRCIPESWRCDGQQDCENGSDEEGCS-PKTCSQDEFRCQDGKCIAPKFVCDS 99 Query: 97 EDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVC 156 + DC DGSDE C PT P C P +C S CI C Sbjct: 100 DRDCLDGSDEASC----------------PT-------PTCGPASFQCNSSTCIPELWAC 136 Query: 157 DGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDV 216 DG DC G DE R H + + +N C + CHSG+ Sbjct: 137 DGDPDCEDGSDEWPQHCRSHSS----------------SLPERSNNPCSALEFHCHSGE- 179 Query: 217 CIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGM-YSCGTKGSEI 275 CI E+NC +E+ +H Y C E Sbjct: 180 CIHSSWRCDGDTDCKDKSDEENCDVATCRPDEFQCSDGTCIHGSRQCDREYDCKDMSDEQ 239 Query: 276 GV------------------CIPMNATCNGIKECPLGDDES-KHC--SECARKR--CDHT 312 G CI ++ CN +++C DE K C +EC + C H Sbjct: 240 GCVNATLCEGPNKFKCQSGECISLDKVCNSVRDCRDWSDEPLKECGTNECLDNKGGCSHI 299 Query: 313 CMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELE 372 C + G C+C EG++L D CED DEC C C + GS+ C+C G++LE Sbjct: 300 CNDLKIGYECLCPEGFQLVDKH-RCEDIDEC-QDPDACSQICVNLEGSYKCQCEEGFQLE 357 Query: 373 TDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHR 432 +CK T YLF + EVR+M L D S Y+++ + ++D Sbjct: 358 PLTKACKAIGTI---AYLFFTNRHEVRKMTL----DRSEYTSL--IPNLKNVVALDTEVA 408 Query: 433 NNKMFMS------ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQK 486 +N+++ S I D S D ++ E++ +AVDWI N+++T Sbjct: 409 SNRIYWSDLSQRKIYSTQIDRAPSFSSYDT----IIGEDLQAPDGLAVDWIHSNIYWTD- 463 Query: 487 SPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANM 546 S +S+ G+ +R +E+G R +VV P+ G + W D + +I + Sbjct: 464 --SILGTVSVADTKGV--KRKTLFQEKGSKPRAIVVDPVHGFMYWTD-WGTPAKIKKGGL 518 Query: 547 DGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH--H 604 +G V L+ ++ P+ + +D +Y+ D + I ++++ R+ V+ + H Sbjct: 519 NGVDVYSLVTEDIQWPNGITLDLSGGRLYWVDSKLHSISSIDVNGGNRKTVLEDKTKLAH 578 Query: 605 PYDMAYFNGFLYWADWGSESL---------KVQEMTHHHSSPQVIHTFNRYPYGIAVN-- 653 P+ +A F ++W D +E++ + M + SP+ I F+ VN Sbjct: 579 PFSLAIFEDKVFWTDIINEAIFSANRLTGSDIHLMAENLLSPEDIVLFHNLTQPRGVNWC 638 Query: 654 -HSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTA-KCVCPDGYTHSVTENSCI 705 + Q G C +LC+ P+ + C CPDG + SC+ Sbjct: 639 ERTALQNG---------GCQYLCLPAPQINPRSPKFTCACPDGMLLAKDMRSCL 683
>gi|3201962|gb|AAC39254.1| low density lipoprotein receptor [Sus scrofa] Length = 801 Score = 202 bits (513), Expect = 2e-50 Identities = 187/714 (26%), Positives = 289/714 (40%), Gaps = 116/714 (16%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F CG RCIP W+CD DC+ G DE GCS CS C++G C+A +F CD Sbjct: 41 DFSCGGRVNRCIPESWRCDGQQDCENGSDEEGCS-PKTCSQDEFCCQDGKCIAPKFVCDS 99 Query: 97 EDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVC 156 + DC DGSDE C PT P C P +C S CI C Sbjct: 100 DRDCLDGSDEASC----------------PT-------PTCGPASFQCNSSTCIPELWAC 136 Query: 157 DGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDV 216 DG DC G DE R H + + +N C + CHSG+ Sbjct: 137 DGDPDCEDGSDEWPQHCRSHSS----------------SLPERSNNPCSALEFHCHSGE- 179 Query: 217 CIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGM-YSCGTKGSEI 275 CI E+NC +E+ +H Y C E Sbjct: 180 CIHSSWRCDGDTDCKDKSDEENCDVATCRPDEFQCSDGTCIHGSRQCDREYDCKDMSDEQ 239 Query: 276 GV------------------CIPMNATCNGIKECPLGDDES-KHC--SECARKR--CDHT 312 G CI ++ CN +++C DE K C +EC + C H Sbjct: 240 GCVNATLCEGPNKFKCQSGECISLDKVCNSVRDCRDWSDEPLKECGTNECLDNKGGCSHI 299 Query: 313 CMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELE 372 C + G C+C EG++L D CED DEC C C + GS+ C+C G++LE Sbjct: 300 CNDLKIGYECLCPEGFQLVDKH-RCEDIDEC-QDPDACSQICVNLEGSYKCQCEEGFQLE 357 Query: 373 TDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHR 432 +CK T YLF + EVR+M L D S Y+++ + ++D Sbjct: 358 PLTKACKAIGTI---AYLFFTNRHEVRKMTL----DRSEYTSL--IPNLKNVVALDTEVA 408 Query: 433 NNKMFMS------ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQK 486 +N+++ S I D S D ++ E++ +AVDWI N+++T Sbjct: 409 SNRIYWSDLSQRKIYSTQIDRAPSFSSYDT----IIGEDLQAPDGLAVDWIHSNIYWTD- 463 Query: 487 SPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANM 546 S +S+ G+ +R +E+G R +VV P+ G + W D + +I + Sbjct: 464 --SILGTVSVADTKGV--KRKTLFQEKGSKPRAIVVDPVHGFMYWTD-WGTPAKIKKGGL 518 Query: 547 DGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH--H 604 +G V L+ ++ P+ + +D +Y+ D + I ++++ R+ V+ + H Sbjct: 519 NGVDVYSLVTEDIQWPNGITLDLSGGRLYWVDSKLHSISSIDVNGGNRKTVLEDKTKLAH 578 Query: 605 PYDMAYFNGFLYWADWGSESL---------KVQEMTHHHSSPQVIHTFNRYPYGIAVN-- 653 P+ +A F ++W D +E++ + M + SP+ I F+ VN Sbjct: 579 PFSLAIFEDKVFWTDIINEAIFSANRLTGSDIHLMAENLLSPEDIVLFHNLTQPRGVNWC 638 Query: 654 -HSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTA-KCVCPDGYTHSVTENSCI 705 + Q G C +LC+ P+ + C CPDG + SC+ Sbjct: 639 ERTALQNG---------GCQYLCLPAPQINPRSPKFTCACPDGMLLAKDMRSCL 683
>gi|476531|pir||QRXLL1 LDL receptor 1 precursor - African clawed frog Length = 909 Score = 201 bits (512), Expect = 3e-50 Identities = 186/710 (26%), Positives = 301/710 (42%), Gaps = 112/710 (15%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F CG RCIP W+CD DC+ G DE+ C++ C+ C++G C++ +F CD Sbjct: 72 QFSCGGRLNRCIPMSWKCDGQTDCENGSDENDCTH-KVCADDQFTCRSGKCISLDFVCDE 130 Query: 97 EDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQCIQPDLV 155 + DC DGSDE +C P C+P +C+ G CI Sbjct: 131 DLDCDDGSDESYCP-----------------------APTCNPAMFQCKDKGICIPKLWA 167 Query: 156 CDGHQDCSGGDDEVNCTRRGHENMQ-----SSTDFH----DDVHL---VDPTFFANEDN- 202 CDG DC G DE +C G E ++ S +FH + +H+ D F + + Sbjct: 168 CDGDPDCEDGSDEEHC--EGREPIKTDKPCSPLEFHCGSGECIHMSWKCDGGFDCKDKSD 225 Query: 203 -------KCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQAD 255 CR C++G CI E+ C Sbjct: 226 EKDCVKPTCRPDQFQCNTG-TCIHGSRQCDREYDCKDLSDEEGCV--------------- 269 Query: 256 HMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHC--SECARKR--CD 310 ++ C ++ C + G CI M+ CN ++C DE K C +EC R C Sbjct: 270 NVTKCEGPDVFKCRS-----GECITMDKVCNKKRDCRDWSDEPLKECGENECLRNNGGCS 324 Query: 311 HTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYE 370 H C + G C+C EGY+L D CED +EC + + C C + +G + C+C GY+ Sbjct: 325 HICNDLKIGYECLCNEGYRLVDQK-RCEDINEC-ENPNTCSQICINLVGGYKCECREGYQ 382 Query: 371 LETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFM 430 ++ SCK T YLF + EVR+M L D S Y+++ + ++D Sbjct: 383 MDPVTASCKSIGTV---AYLFFTNRHEVRKMTL----DRSEYTSV--IPRLKNVVALDME 433 Query: 431 HRNNKMFMSISDEHGDPTGELSVSDNGLMR--VLRENVIGVSNVAVDWIGGNVFFTQKSP 488 +NK++ S + + + +DN V+ + +AVDWI GN+++T Sbjct: 434 IASNKIYWSDLTQRKIYSASMEKADNTSHHETVISNQIQAPDGIAVDWIHGNIYWTD--- 490 Query: 489 SPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDG 548 S + IS+ G +R + + R +VV P +G + W D + +I ++G Sbjct: 491 SKFSTISVANTEG--SKRRTPPSDDLEKPRDIVVDPSQGFMYWTD-WGLPAKIEKGGLNG 547 Query: 549 SQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH--HPY 606 L+ +E P+ + +D I +Y+ D + + +++ + RR VIS+ H HP+ Sbjct: 548 VDRYPLVTENIEWPNGITLDLINQRLYWVDSKLHSLSCIDVTGENRRTVISDETHLAHPF 607 Query: 607 DMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPC 666 + F ++W D +E++ + +V P I + H+L Q P + Sbjct: 608 GLTIFEDLVFWTDIENEAIFSANRLTGRNIMKVAEDL-LSPEDIVLYHNLRQ--PKAENW 664 Query: 667 LELE------CPWLCVIVPKSDFIMTAK-----CVCPDGYTHSVTENSCI 705 E C +LC+ P +TA+ C CPDG SC+ Sbjct: 665 CEAHHLGNGGCEYLCLPAPH----ITARSPKFTCACPDGMHLGADMRSCV 710
>gi|21294092|gb|EAA06237.1| agCP13423 [Anopheles gambiae str. PEST] Length = 4561 Score = 201 bits (511), Expect = 4e-50 Identities = 201/790 (25%), Positives = 302/790 (38%), Gaps = 126/790 (15%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYA---HHCSTSFMLCKN 84 N C+Q +F C N RCIP +W CD DC G DES CS S C N Sbjct: 3644 NCPQCNQETDFKCNNN--RCIPRQWMCDFADDCGDGSDESETQCKGKYRECSESEFRCDN 3701 Query: 85 GLCVANEFKCDGEDDCRDGSDEQHCEYNILKS---------------RFDGSNP------ 123 G C+++ ++CD EDDC D SDE CE K+ R DG Sbjct: 3702 GKCISSRWRCDHEDDCGDNSDEYGCEGFQCKNGTFQCKSGHCIAAYFRCDGDRDCRDMSD 3761 Query: 124 --SAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVN--CTRRGHENM 179 P F G G C R +C + C+ P +CDG DC DE CT + + Sbjct: 3762 EIGCPPRFPG--GRYCPESRFQCANNLCVLPSDLCDGTDDCGDNSDEAASVCTNFNCDTL 3819 Query: 180 QSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC 239 + F +++C + Y +C D C Sbjct: 3820 RR---------------FQCANHRCVARYQICDGVDNC---------------------- 3842 Query: 240 QTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE-- 297 S+E ++ A C Y C K CI C+ +C G DE Sbjct: 3843 --GDGSDENNMTLCAARQKPCDLYTQYQCANKK-----CIDRAQVCDYADDCGDGSDELG 3895 Query: 298 ---SKHCSECARKRCDHTCMNTPHGARCICQEGYKL-ADDGLTCEDEDECATHGHLCQHF 353 + CS + C+H C+N G C C G+ + A + C D DECAT H C H Sbjct: 3896 CHRTASCSALNKGGCEHHCVNLTDGYICACYAGFIIDASNKKRCTDIDECATGTHGCSHL 3955 Query: 354 CEDRLGSFACKCANGYEL-ETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNY 412 C + G++ C C G+ L + CK E L +S G E+R + + Sbjct: 3956 CTNLNGTYECGCREGFRLSDRVSGVCK---ALKGEPLLVLSGGPEIRAY------EPAQN 4006 Query: 413 SAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGV--- 469 AG I ++D+ + +F + S + + + NG +V + + Sbjct: 4007 RQFDVIAGEKRIEALDYNPESQMIFWTDSYDKTIKRSYMVNAMNGDAKVGYAQDLNMKGG 4066 Query: 470 ---SNVAVDWIGGNVFFTQKSPS---PSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVH 523 + +AVDW+ N+++ + + P I + G + R +++ + + + V Sbjct: 4067 TKPTALAVDWVADNLYWAETDRTGSKPRGRIMVAKTDGRYRRALVQAGLEVPT--AIAVD 4124 Query: 524 PMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIR-HDVYFGDVERQ 582 P G + W D+ +I ++ MDGS+ R ++ + P+ L +DY + H VY+ D + Sbjct: 4125 PQLGRMFWADA-GSAPKIEVSWMDGSKRRPIITEAIRHPAGLTVDYSQDHAVYWVDTKLN 4183 Query: 583 LIERVNIDTKERRVVISNG-VHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIH 641 IE + D RR V+ + HP + F LYW + L Q+ V Sbjct: 4184 TIEVMKPDGTMRRTVLKGDLLKHPVSLDVFESSLYWVTRDTGELLRQDKFGRGVQVTVQR 4243 Query: 642 TFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTE 701 P I V H L +NPC C LC++VP +C CPD T + Sbjct: 4244 NLAN-PSSIKVYHELRYNTTLNNPCYRNPCSHLCLLVPGG-----RRCSCPDN-TVPTSH 4296 Query: 702 NSCIPPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGR-AHRIVCDC 760 S V E + C NGG C+E G + +VC C Sbjct: 4297 RSTAEVVCDAPAERPRPAPRV------------CPCQNGGLCKEADAGPGAPSSELVCVC 4344 Query: 761 EGPYDGQYCE 770 + G +CE Sbjct: 4345 LPEFSGTHCE 4354
Score = 187 bits (475), Expect = 7e-46 Identities = 200/743 (26%), Positives = 309/743 (41%), Gaps = 132/743 (17%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESG--C-SYAHHCSTSFMLCKNGLC 87 TC Q F C N RCIPA W CD DC G DE C S C C NG C Sbjct: 2769 TCPQ-NSFRCPNH--RCIPATWYCDGDDDCGDGADEPPEYCKSEGRTCFGDLFTCDNGNC 2825 Query: 88 VANEFKCDGEDDCRDGSDE------------QHCEYNILKSRFDGSNPSAPTTFVGHNGP 135 + + CDG++DC D SDE + E+ +++ P ++ P Sbjct: 2826 IPRIYICDGDNDCLDNSDEDNRHQCNDRKCDEDTEFTCHENKAWARAQCIPKKWICDGDP 2885 Query: 136 EC-----------HPPR--------LRCRSGQCIQPDLVCDGHQDCSGGDDE-VNCTRRG 175 +C H P C +G+CI VCD DC G DE NC Sbjct: 2886 DCVDGADENTTLQHCPSPQPCGEDMFTCANGRCINQGWVCDHDNDCGDGSDEGKNC---- 2941 Query: 176 HENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXX 235 N Q T P F ++ KC C D C Sbjct: 2942 --NSQYKT--------CTPQEFTCQNFKCIRNQYRCDGEDDC-------------GDHSD 2978 Query: 236 EKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGD 295 E C+ + ++ A G ++C G CI + CN + +C Sbjct: 2979 EVGCKKD---------------NATCAEGKFTCNN-----GQCIDYHLVCNKVPDCTDES 3018 Query: 296 DESKHCS--ECAR---KRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLC 350 DE HC+ ECA+ RC H C++T C C +GYKL +DG C D DEC +C Sbjct: 3019 DEPLHCNVDECAKVEIHRCGHKCVDTLTSYYCDCNQGYKLLEDGKACADIDECIETPGVC 3078 Query: 351 QHFCEDRLGSFACKC-ANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDG 409 C + G + CKC YE + D H+CK + T P +L S VR M TDG Sbjct: 3079 SQHCSNTPGGYYCKCDERYYERQNDEHTCKRKDDTKP--WLIFSNKYYVRNMS----TDG 3132 Query: 410 SNYSAIQKFAGHGTIRSIDF-MHRNNKMFMSISDEHGDPTGELSVSDNGL----MRVLRE 464 Y+ I + + +IDF M ++ F ++ + + S+ ++G+ V++ Sbjct: 3133 HQYNLIHQ--DLMNVVAIDFDMQQHEMYFCDVTAKTIFKSSFGSLVEDGVRIEKTPVIKH 3190 Query: 465 NVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHP 524 + G+ +A+DW+G +++ + S + + + G + + G R +VVHP Sbjct: 3191 DSHGLEGIAIDWVGRKLYWLDRH---SKNLDVAELDGTRRKTLRSGVVDP---RAIVVHP 3244 Query: 525 MRGLIIWIDSYQKYHRIMMANMDGSQ-VRILL-DNKLEVPSALAIDYIRHDVYFGDVERQ 582 G ++ S+ I MDGS RIL ++ + P+AL IDY +Y+ D Sbjct: 3245 GIGY-LYFTSWHLQAYIAKMGMDGSNFTRILTWEDDIAWPNALTIDYFTDRIYWADAHLD 3303 Query: 583 LIERVNIDTKERRVVISNG-VHHPYDMAYFNGFLYWADWGSES-LKVQEMTHHHSSPQVI 640 I +++ + R VV+S V H + ++ F+ LYW DW ++ L+ + T + + V+ Sbjct: 3304 YIAFADLEGRHRHVVLSGARVPHVFALSIFDDSLYWTDWNLKAILRANKFTGANYT--VV 3361 Query: 641 HTFNRYPYGIAVNHSLYQTGPPSNPCLELE--CPWLCVIVP--KSDFIM----------T 686 PY + ++H L Q P NPC C LC++ P +S ++ + Sbjct: 3362 RNTTHRPYDVHISHPLRQI-PFPNPCGTTNGGCSHLCLLAPPLESTYLNVEGYLEEGAPS 3420 Query: 687 AKCVCPDGYTHSVTENSCIPPVT 709 +C CP+ + + + +CI T Sbjct: 3421 YRCACPNQFYLARDQKTCIANCT 3443
Score = 173 bits (438), Expect = 1e-41 Identities = 188/739 (25%), Positives = 291/739 (39%), Gaps = 138/739 (18%) Query: 18 IKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCST 77 + N+ + TC EF C +G RCIP ++CD DC DE C C+ Sbjct: 964 LDNSDEEQNCTKPTCG-TNEFQCKSG--RCIPLNFRCDQENDCGDHSDEFECGNV-TCAA 1019 Query: 78 SFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSA----PTTFVGHN 133 S C+NG C+ N +KCD E+DC DGSDE + F + P P ++V Sbjct: 1020 SQFACENGRCIPNIWKCDSENDCGDGSDEGPFCAEKTCAYFQFTCPRTGHCIPQSWVCDG 1079 Query: 134 GPECH--------PP------RLRCRS-GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHEN 178 +C PP + +C QC++ CDG DC+ G DE+ C Sbjct: 1080 DDDCFDKQDEKDCPPITCLANQFKCADLRQCVEEPYKCDGIPDCNDGSDELGC------- 1132 Query: 179 MQSSTDFHDDVHLVDPTFFANEDNKCR-SGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEK 237 PT E N+C + C S VCIP E+ Sbjct: 1133 ---------------PTM---EPNQCNLEKHFRCRSSGVCIPIAWHCDGSNDCDDHSDEE 1174 Query: 238 NCQTNAPSEEEYLSGQADHM---------------------HSC------SAAGMYSCGT 270 +C Y A + H+C A G ++C Sbjct: 1175 DCSKITCPNGFYKCANAKCVFKAYICDGKDDCGDGSDESVEHACVTPPQRCAHGQWACPG 1234 Query: 271 KGSEIGVCIPMNATCNGIKECPLGDDESKHC--SECARKR--CDHTCMNTPHGARCICQE 326 C+ + + C+ + +CP G DE C ++C + C + C TP GA CIC Sbjct: 1235 VTER---CVNLTSVCDDVPDCPNGADEGLGCDLAQCQHQTGLCSNGCQKTPLGALCICPP 1291 Query: 327 GYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTP 386 G +LA D TC+D +EC G LC C + GS+ C C +GY LE + H+CK A P Sbjct: 1292 GEELAPDNFTCKDLNECDPPG-LCSQRCTNTKGSYFCSCVDGYVLEPNKHTCK--AVNHP 1348 Query: 387 EGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGD 446 +L IS + +AD + + + + N + + S+ H Sbjct: 1349 AAFLIIS---NRHSILVADLKEQG-------------LERVPIIVEN--VVATASNMH-- 1388 Query: 447 PTGELSVSDNGLMRVLR-------ENVIG-----VSNVAVDWIGGNVFFTQKSPSPSAGI 494 TG + SD L ++ R + +I V +A DWIG N+++ S I Sbjct: 1389 -TGTIFWSDMKLKKISRLDRGMEPQEIISTGLDLVEGLAYDWIGQNLYWLD---SKLNTI 1444 Query: 495 SICTMSGMFCRRVIEGKEQGQSYRGLVV--HPMRGLIIWIDSYQKYHRIMMANMDGSQVR 552 + +G R++ +E RG+ + P + W D + + RI MDG+ Sbjct: 1445 EVAHENG--SNRLVLVRENITQPRGMCLDPSPTAKWLFWTD-WGENPRIERIGMDGTMRE 1501 Query: 553 ILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI--SNGVHHPYDMAY 610 ++ K+ P+ L +D VYF D + I+ + R+ V+ S+ + H + ++ Sbjct: 1502 TIVSTKIYWPNGLTLDVATQRVYFADSKLDFIDFCYYNGTGRQQVLAASHYLLHAHSLSL 1561 Query: 611 FNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE 670 F LYW D +++ S+ + T P + V+H Q S PC Sbjct: 1562 FEDTLYWTD--------RQLNRVLSAHKYRGTNQTVPLSVHVHHPSLQPMYES-PCKRAA 1612 Query: 671 CPWLCVIVPKSDFIMTAKC 689 C +C++ P KC Sbjct: 1613 CQHVCLLSPSEPAGYACKC 1631
Score = 90.1 bits (222), Expect = 1e-16 Identities = 91/347 (26%), Positives = 158/347 (45%), Gaps = 27/347 (7%) Query: 343 CATHGHLCQHFCEDRLG-SFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 C + C+H C G S C C GY+ E + A T + + +S R Sbjct: 1933 CTQNNGGCEHLCLPHAGASRVCACGVGYKKENE------VACTPYKTFAVVSQLDVTRGF 1986 Query: 402 PLADFTDGSNYSAIQKFAGHG-TIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNG--L 458 L D T+ A+ AG G I +D ++R + ++ + G G V NG L Sbjct: 1987 SLRDSTE-----AMVPIAGPGHHILHVDVLYRESWIYW-VEYNRGHWNGIFRVRPNGTEL 2040 Query: 459 MRVLRENV--IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQS 516 ++++ + G+ +A+DW+ GN++FT P + + + + G R + K + Sbjct: 2041 QHIVKDGIGSNGIRGIAIDWVAGNLYFTNVFPHENY-VEVAWLDGT--HRKVLVKTTNDA 2097 Query: 517 YRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYF 576 R L V+P++ L+ WID Y +Y RI +DGS ++ + + P L +D + HDVY+ Sbjct: 2098 PRELAVNPIKRLLYWID-YGQYPRIGKCFLDGSNWTPVVTSGISNPRDLTVDMLTHDVYW 2156 Query: 577 GDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL-KVQEMTHHHS 635 D + +I++V+ R+V+ N + +P +A F +YW D S+ + + + + Sbjct: 2157 VDSKLDMIQKVSYSGGHRQVIRRN-LANPMALAVFLTDVYWVDRNLASVFRASKFPGNST 2215 Query: 636 SPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLEL---ECPWLCVIVP 679 P+ + T I + Q +NPCL L C LC +P Sbjct: 2216 RPERLRTNLPKLRDITIYDINSQPMDDANPCLRLGNGGCDQLCFALP 2262
Score = 88.2 bits (217), Expect = 5e-16 Identities = 92/367 (25%), Positives = 132/367 (35%), Gaps = 87/367 (23%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 Q + N T Q + CG +CIP W+CD DC DE A HC C Sbjct: 3435 QKTCIANCTSGQHR---CGGDDEKCIPWFWKCDGEPDCKDRSDEPASCPARHCRAGTFQC 3491 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL 142 NG C + CDG DDC DG+DEQ+C+ C Sbjct: 3492 GNGNCTPSTTICDGTDDCGDGTDEQNCDL------------------------PCPVSDF 3527 Query: 143 RCR-SGQCIQPDLVCDGHQDCSGGDDEVN--CTRRGHENMQSST-------------DFH 186 +C+ SG+CI CDG DC G DE C +R + + DF Sbjct: 3528 KCKSSGRCILDSWKCDGDADCKDGSDEDPEICHKRTCDPETEFSCKNGRCIPKLWMCDFD 3587 Query: 187 DDV--HLVDPTFFANEDNKCRSGYTMC--HSGDVCIPXXXXXXXXXXXXXXXXE--KNCQ 240 +D +P + + N C +G++ C S CIP E +NC Sbjct: 3588 NDCGDDSDEPAYMCRQRN-CTTGWSRCPGQSNYRCIPKWLFCDGKDDCRDKSDELPENCP 3646 Query: 241 TNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKH 300 C+ + C CIP C+ +C G DES+ Sbjct: 3647 ------------------QCNQETDFKCNNNR-----CIPRQWMCDFADDCGDGSDESET 3683 Query: 301 CSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHG--HLCQHF-CEDR 357 + + C + +G +CI C+ ED+C + + C+ F C++ Sbjct: 3684 QCKGKYRECSESEFRCDNG-KCISSR--------WRCDHEDDCGDNSDEYGCEGFQCKN- 3733 Query: 358 LGSFACK 364 G+F CK Sbjct: 3734 -GTFQCK 3739
Score = 86.7 bits (213), Expect = 2e-15 Identities = 84/303 (27%), Positives = 103/303 (33%), Gaps = 87/303 (28%) Query: 42 NGRLR--CIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGL-CVANEFKCDGED 98 NGR+ C+P E +CD DC G+DE GC C C NG+ C+ KC+ ++ Sbjct: 49 NGRVAEICVPKEKRCDGYLDCRTGKDEEGCP-GTACRLDQFRCANGVRCIDTALKCNHKN 107 Query: 99 DCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDG 158 DC D SDE VG N P CH + RC + CI CDG Sbjct: 108 DCGDNSDE-----------------------VGCNFPPCHGGQFRCANALCIPATFHCDG 144 Query: 159 HQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCI 218 + DCS DE NCT D + P N KC +C C Sbjct: 145 YHDCSDESDEANCTAIACP----------DNKFLCPRGGPNGQAKCIVKSKLCDGKRDC- 193 Query: 219 PXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGM-YSCGTKGSEIGV 277 E C T SC A G + CG + GV Sbjct: 194 -----------DDGTDEETACSTT----------------SCPALGCEHKCGPSLTG-GV 225 Query: 278 CI--------PMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTPHGARCICQEGYK 329 C P N TC + EC + CD C NT C C GY Sbjct: 226 CYCPAGRTLSPDNRTCADLDECTVWG------------HCDQLCTNTDGSFSCACATGYT 273 Query: 330 LAD 332 L + Sbjct: 274 LME 276
Score = 85.5 bits (210), Expect = 3e-15 Identities = 107/442 (24%), Positives = 150/442 (33%), Gaps = 114/442 (25%) Query: 20 NTAQAPAVNNSTCDQAK----------------------------------------EFD 39 N + A N TCD +K EF Sbjct: 2592 NEGRMCAPKNHTCDASKFYCQNGKCISRMWSCDGDDDCGDGSDEDVNYCAFHSCAANEFR 2651 Query: 40 CGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDD 99 C NG RCI W+CD+ DC G DE GCSY C C NG C+ C+G +D Sbjct: 2652 CANG--RCIFKSWKCDHENDCKDGSDEEGCSYP-PCVDGEFTCANGRCIPQAQVCNGVND 2708 Query: 100 CRDG--SDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRC-RSGQCIQPDLVC 156 C+D SDE H PT C P L+C R+ C++P +C Sbjct: 2709 CKDNGTSDETH--------------ERCPTN------TTCPPNHLKCDRTNICVEPYWLC 2748 Query: 157 DGHQDCSGGDDE--VNCTRR----------GHENMQSS-----TDFHDDVHLVDPTFFAN 199 DG DC DE ++C +R H + ++ D D P + + Sbjct: 2749 DGDNDCGDNSDENPLHCAQRTCPQNSFRCPNHRCIPATWYCDGDDDCGDGADEPPEYCKS 2808 Query: 200 EDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHS 259 E C C +G+ CIP + +C N+ + + Sbjct: 2809 EGRTCFGDLFTCDNGN-CIP---------RIYICDGDNDCLDNSDEDNRHQCND----RK 2854 Query: 260 CSAAGMYSCG-TKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTPH 318 C ++C K CIP C+G +C G DE+ C + M T Sbjct: 2855 CDEDTEFTCHENKAWARAQCIPKKWICDGDPDCVDGADENTTLQHCPSPQPCGEDMFTCA 2914 Query: 319 GARCI-----------CQEGYKLADDGLTCEDE-DECATHGHLCQHFCEDRLGSFACKCA 366 RCI C +G +D+G C + C CQ+F R + C Sbjct: 2915 NGRCINQGWVCDHDNDCGDG---SDEGKNCNSQYKTCTPQEFTCQNFKCIR-NQYRCDGE 2970 Query: 367 NGYELETDGHSCKYEATTTPEG 388 + +D CK + T EG Sbjct: 2971 DDCGDHSDEVGCKKDNATCAEG 2992
Score = 71.2 bits (173), Expect = 7e-11 Identities = 79/326 (24%), Positives = 128/326 (39%), Gaps = 42/326 (12%) Query: 360 SFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFA 419 SF C CA G L DG C+ + Y+ + E+R + D S A Sbjct: 2270 SFRCDCAVG-RLGADGRHCELT-----DEYIIFATRTEIRAI---DLDPASTNVPFAPVA 2320 Query: 420 GHGTIRSIDFMHRNNKMFMS-------ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNV 472 + +DF + +NK+F + I+ GD D + + I + Sbjct: 2321 NLTNVVGLDFDYADNKLFFTQIRPWSKIAWLRGDK------PDAAAITPVMTRGINPEGI 2374 Query: 473 AVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWI 532 A DW +++T S + ++ + RV + R +V+ P G + + Sbjct: 2375 AYDWTQRKIYWTDSSNNSIYAMNTDGTELVMIARV-------ERPRAIVLDPCNGTLYFT 2427 Query: 533 D--SYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNID 590 D + +I M GS R ++D L PS LAIDY +Y+ D R+ IER +D Sbjct: 2428 DWGRFGTSGKIFRTTMAGSLKRAIIDRDLSQPSGLAIDYDDRMLYWTDAVREKIERSQLD 2487 Query: 591 TKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL---------KVQEMTHH-HSSPQVI 640 + R V+IS + +P+ + F ++YW D + V EM SP+ I Sbjct: 2488 GRNREVLISATI-YPFAITVFRNYIYWTDLQLRGVYRAEKHTGAGVHEMVKRLEDSPRDI 2546 Query: 641 HTFNRYPYGIAVNHSLYQTGPPSNPC 666 H ++ N L G + C Sbjct: 2547 HIYSATRQQCQANPCLQNNGGCAQSC 2572
Score = 71.2 bits (173), Expect = 7e-11 Identities = 83/371 (22%), Positives = 147/371 (39%), Gaps = 36/371 (9%) Query: 361 FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAG 420 + C C G++L D +C +L S ++ L +G + + + + Sbjct: 577 YRCACHTGWQLSKDLMNCHL-----VRQFLMYSQQRFIKGKVLDPVIEGFSDAILPVVSR 631 Query: 421 HGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGN 480 +DF + ++ SD D + + G VL GV +AVDW+ N Sbjct: 632 RARFVGLDFDAVDEHIYY--SDVLQDVIYRVHRNGTGREIVLASQNEGVEGLAVDWVSKN 689 Query: 481 VFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHR 540 +++ S +++ + RR + + + R +VVHP RG I+ + + Sbjct: 690 LYYID---SRKGTLNVLSTRNTSYRRTL--LKNLKRPRAIVVHPNRGY-IYFSEWDRPAN 743 Query: 541 IMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN 600 I AN DGS + + + L P+ L+ID+ VY+ D ++ N+D + R V S Sbjct: 744 ISRANADGSGLIVFRNLTLGWPNGLSIDFREDRVYWCDALLDHVQHANLDGTDVRTVNSR 803 Query: 601 GVHHPYDMAYFNGFLYWADWGSESL-KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQT 659 + HP+ + ++Y DW +++ ++ ++ V YG+ V Q+ Sbjct: 804 LIRHPFSIVIHEEWMYITDWRLDAIVRLNKLNGEQEEIMVREPQTNRLYGVKVYSHGVQS 863 Query: 660 GPPSNPC--LELECPWLCVIVPKSDF--------------IMTAKCVCPDGYTHSVTENS 703 S PC C LC +P++D + KC CP G S Sbjct: 864 IDASQPCGVNNGGCEKLCFALPRNDTEDAAAASAGGPTSPRLVVKCGCPYGERLGDDGRS 923 Query: 704 CI------PPV 708 C+ PPV Sbjct: 924 CLSDPNAEPPV 934
Score = 62.8 bits (151), Expect = 2e-08 Identities = 71/273 (26%), Positives = 88/273 (32%), Gaps = 77/273 (28%) Query: 86 LCVANEFKCDGEDDCRDGSDEQHCEYNILK-SRFDGSNP----------------SAPTT 128 +CV E +CDG DCR G DE+ C + +F +N + Sbjct: 55 ICVPKEKRCDGYLDCRTGKDEEGCPGTACRLDQFRCANGVRCIDTALKCNHKNDCGDNSD 114 Query: 129 FVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDD 188 VG N P CH + RC + CI CDG+ DCS DE NCT D Sbjct: 115 EVGCNFPPCHGGQFRCANALCIPATFHCDGYHDCSDESDEANCTAIACP----------D 164 Query: 189 VHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEE 248 + P N KC +C C E C T Sbjct: 165 NKFLCPRGGPNGQAKCIVKSKLCDGKRDC------------DDGTDEETACSTT------ 206 Query: 249 YLSGQADHMHSCSAAGM-YSCGTKGSEIGVCI--------PMNATCNGIKECPLGDDESK 299 SC A G + CG + GVC P N TC + EC + Sbjct: 207 ----------SCPALGCEHKCGPSLTG-GVCYCPAGRTLSPDNRTCADLDECTVWG---- 251 Query: 300 HCSECARKRCDHTCMNTPHGARCICQEGYKLAD 332 CD C NT C C GY L + Sbjct: 252 --------HCDQLCTNTDGSFSCACATGYTLME 276
Score = 57.4 bits (137), Expect = 9e-07 Identities = 65/282 (23%), Positives = 93/282 (32%), Gaps = 82/282 (29%) Query: 64 RDESGCSYAHHCSTSFMLC--KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGS 121 RD+ C +C++ C + C+ +KCDGE DC+D SDE Sbjct: 3433 RDQKTC--IANCTSGQHRCGGDDEKCIPWFWKCDGEPDCKDRSDEP-------------- 3476 Query: 122 NPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQS 181 S P C +C +G C +CDG DC G DE NC Sbjct: 3477 -ASCPAR-------HCRAGTFQCGNGNCTPSTTICDGTDDCGDGTDEQNC---------- 3518 Query: 182 STDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQT 241 D C C S CI + +C+ Sbjct: 3519 -------------------DLPCPVSDFKCKSSGRCI---------LDSWKCDGDADCKD 3550 Query: 242 NAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHC 301 + + E H +C +SC G CIP C+ +C GDD + Sbjct: 3551 GSDEDPEIC-----HKRTCDPETEFSCKN-----GRCIPKLWMCDFDNDC--GDDSDEPA 3598 Query: 302 SECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDEC 343 C ++ C T +RC Q Y+ L C+ +D+C Sbjct: 3599 YMCRQRNC------TTGWSRCPGQSNYRCIPKWLFCDGKDDC 3634
Score = 54.3 bits (129), Expect = 7e-06 Identities = 47/156 (30%), Positives = 67/156 (42%), Gaps = 29/156 (18%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNG------LCVAN 90 +F C N CIPA + CD DC DE+ C+ A C + LC G C+ Sbjct: 127 QFRCANA--LCIPATFHCDGYHDCSDESDEANCT-AIACPDNKFLCPRGGPNGQAKCIVK 183 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHN-GPECHPPRLRCRSGQC 149 CDG+ DC DG+DE+ S S P H GP C +G+ Sbjct: 184 SKLCDGKRDCDDGTDEETA----------CSTTSCPALGCEHKCGPSLTGGVCYCPAGRT 233 Query: 150 IQPDLVCDGHQDCSGGDDEVNCTRRGH-ENMQSSTD 184 + PD ++ C+ D+ CT GH + + ++TD Sbjct: 234 LSPD-----NRTCADLDE---CTVWGHCDQLCTNTD 261
Score = 53.5 bits (127), Expect = 2e-05 Identities = 72/303 (23%), Positives = 118/303 (38%), Gaps = 46/303 (15%) Query: 350 CQHFC---EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADF 406 CQH C +ACKC GY L +G + E ++ + G ++ +P F Sbjct: 1613 CQHVCLLSPSEPAGYACKCRPGYRLLPEGRCTEEE-----NAFIMLLKGNQIVDVP---F 1664 Query: 407 TDG-SNYSAIQKFAGHGTIRSIDFMHRNNKMF-MSISDEHGD--------PTG-----EL 451 G + S + G S+D+ + ++ + DE D P G E Sbjct: 1665 NGGDARSSGLMPVVGIEGGISLDYDRKGEMVYWVQGRDESDDENCTIYATPYGGGNRTEF 1724 Query: 452 SVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGK 511 D GL V +A DWIG N++ + S IS+ G R + Sbjct: 1725 LGPDTGL-------VGAAYTIAFDWIGRNLYVGNRLASNIEAISV---DGKVRYRTVVLA 1774 Query: 512 EQGQSY-----RGLVVHPMRGLIIWIDS--YQKYHRIMMANMDGSQVRILLDNKLEVPSA 564 G + L + P G + WID + ++ A MDGS R+ LD+ ++ P + Sbjct: 1775 NDGNRTSVAKPKQLALDPADGRLFWIDEGGFGVLTKVASAGMDGSDPRV-LDDTVQFPES 1833 Query: 565 LAIDYIRHDVYFGDVERQLIERVNIDTKERRVVIS--NGVHHPYDMAYFNGFLYWADWGS 622 + +D + VY+ + + D +R ++S N + P +A LY+ D Sbjct: 1834 ITVDAEKRRVYYSTRLPPAVLSIEYDGTGQRTILSEENAISKPRALAVLESRLYFLDPTY 1893 Query: 623 ESL 625 E L Sbjct: 1894 EKL 1896
Score = 48.9 bits (115), Expect = 4e-04 Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 8/96 (8%) Query: 20 NTAQAPAV-NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTS 78 N+ +A +V N CD + F C N RC+ CD V +C G DE+ + Sbjct: 3803 NSDEAASVCTNFNCDTLRRFQCANH--RCVARYQICDGVDNCGDGSDENNMTLCAARQKP 3860 Query: 79 FML-----CKNGLCVANEFKCDGEDDCRDGSDEQHC 109 L C N C+ CD DDC DGSDE C Sbjct: 3861 CDLYTQYQCANKKCIDRAQVCDYADDCGDGSDELGC 3896
Score = 34.7 bits (78), Expect = 6.0 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 3/43 (6%) Query: 302 SECARKRCDHTCM---NTPHGARCICQEGYKLADDGLTCEDED 341 S C R C H C+ + P G C C+ GY+L +G E+E+ Sbjct: 1606 SPCKRAACQHVCLLSPSEPAGYACKCRPGYRLLPEGRCTEEEN 1648
>gi|547838|sp|Q99087|LDL1_XENLA Low-density lipoprotein receptor 1 precursor (LDL receptor 1) gi|214574|gb|AAA49897.1| low density lipoprotein receptor-1 Length = 909 Score = 200 bits (508), Expect = 9e-50 Identities = 186/710 (26%), Positives = 301/710 (42%), Gaps = 112/710 (15%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F CG RCIP W+CD DC+ G DE+ C++ C+ C++G C++ +F CD Sbjct: 72 QFSCGGRLNRCIPMSWKCDGQTDCENGSDENDCTH-KVCADDQFTCRSGKCISLDFVCDE 130 Query: 97 EDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQCIQPDLV 155 + DC DGSDE +C P C+P +C+ G CI Sbjct: 131 DLDCDDGSDESYCP-----------------------APTCNPAMFQCKDKGICIPKLWA 167 Query: 156 CDGHQDCSGGDDEVNCTRRGHENMQ-----SSTDFH----DDVHL---VDPTFFANEDN- 202 CDG DC G DE +C G E ++ S +FH + +H+ D F + + Sbjct: 168 CDGDPDCEDGSDEEHC--EGREPIKTDKPCSPLEFHCGSGECIHMSWKCDGGFDCKDKSD 225 Query: 203 -------KCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQAD 255 CR C++G CI E+ C Sbjct: 226 EKDCVKPTCRPDQFQCNTG-TCIHGSRQCDREYDCKDLSDEEGCV--------------- 269 Query: 256 HMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHC--SECARKR--CD 310 ++ C ++ C + G CI M+ CN ++C DE K C +EC R C Sbjct: 270 NVTKCEGPDVFKCRS-----GECITMDKVCNKKRDCRDWSDEPLKECGENECLRNNGGCS 324 Query: 311 HTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYE 370 H C + G C+C EGY+L D CED +EC + + C C + +G + C+C GY+ Sbjct: 325 HICNDLKIGYECLCNEGYRLVDQK-RCEDINEC-ENPNTCSQICINLVGGYKCECREGYQ 382 Query: 371 LETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFM 430 ++ SCK T YLF + EVR+M L D S Y+++ + ++D Sbjct: 383 MDPVTASCKSIGTV---AYLFFTNRHEVRKMTL----DRSEYTSV--IPRLKNVVALDME 433 Query: 431 HRNNKMFMSISDEHGDPTGELSVSDNGLMR--VLRENVIGVSNVAVDWIGGNVFFTQKSP 488 +NK++ S + + + +DN V+ + +AVDWI GN+++T Sbjct: 434 IASNKIYWSDLTQRKIYSASMEKADNTSHHETVISNQIQAPDGIAVDWIHGNIYWTD--- 490 Query: 489 SPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDG 548 S + IS+ G +R + + R +VV P +G + W D + +I ++G Sbjct: 491 SKFSTISVANTEG--SKRRTPPSDDLEKPRDIVVDPSQGFMYWTD-WGLPAKIEKGGLNG 547 Query: 549 SQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH--HPY 606 L+ +E P+ + +D I +Y+ D + + +++ + RR VIS+ H HP+ Sbjct: 548 VDRYPLVTENIEWPNGITLDLINQRLYWVDSKLHSLSCIDVTGENRRTVISDETHLAHPF 607 Query: 607 DMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPC 666 + F ++W D +E++ + +V P I + H+L Q P + Sbjct: 608 GLTIFEDLVFWTDIENEAIFSANRLTGRNIMKVAEDL-LSPEDIVLYHNLRQ--PKAENW 664 Query: 667 LELE------CPWLCVIVPKSDFIMTAK-----CVCPDGYTHSVTENSCI 705 E C +LC+ P +TA+ C CPDG SC+ Sbjct: 665 CEAHHLGNGGCEYLCLPAPH----ITARSPKFTCACPDGMHLGDDMRSCV 710
>gi|16519539|ref|NP_443737.1| low density lipoprotein-related protein 1B (deleted in tumors); low density lipoprotein receptor related protein LRP1B/LRP-DIT [Mus musculus] gi|8926243|gb|AAF81758.1|AF270884_1 low density lipoprotein receptor related protein LRP1B/LRP-DIT [Mus musculus] Length = 4599 Score = 200 bits (508), Expect = 1e-49 Identities = 223/855 (26%), Positives = 337/855 (39%), Gaps = 176/855 (20%) Query: 24 APAVNNSTCDQAK----EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSF 79 A A + + CD+ EF C N CIP W+CDN DC DE C C+ Sbjct: 3463 ADASDEANCDKKTCGPHEFQCKNN--NCIPDHWRCDNQNDCSDNSDEDNCK-PQTCTLKD 3519 Query: 80 MLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNP---SAPTTFVGHNG-- 134 LC NG CV++ F CDGE DC DGSDE++CE + K +F SN SA GH Sbjct: 3520 FLCSNGDCVSSRFWCDGEFDCADGSDEKNCETSCSKDQFQCSNGQCLSAKWKCDGHEDCK 3579 Query: 135 ------------PECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSS 182 P C C SG C+ L C+G DC G DE++C E+ Sbjct: 3580 YGEDEKNCEPAFPVCSSSEYMCASGGCLSASLKCNGEPDCVDGSDEMDCVIECKEDQFQC 3639 Query: 183 TD-------------FHDDVHLVDPTFFANEDNKCRSGYTMCHSG--------------- 214 + +D V D + CR +C++ Sbjct: 3640 KNKAYCIPIRWLCDGIYDCVDGSDEETCGRGGSICRDDEFLCNNSLCKLHFWVCDGEDDC 3699 Query: 215 --------DVCI----PXXXXXXXXXXXXXXXXEKNCQ----TNAPSEEEYLSGQADHMH 258 D+C+ P EK C S+EE+ SG+ Sbjct: 3700 GDNSDEAPDMCVKFLCPPTRPYRCRNDRICLQLEKICNGINDCGDNSDEEHCSGKLSLKS 3759 Query: 259 SCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMN--T 316 ++C + CIPM C+ + +C G DE C + +HTC N Sbjct: 3760 KPCKKDEFTCSNRN-----CIPMELQCDSLDDCGDGSDEQG----CLKTPIEHTCENNGN 3810 Query: 317 PHG-----------ARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKC 365 P G C C+ G++ G C D +EC G +C H C + GS+ C C Sbjct: 3811 PCGDDAYCNQIKTSVFCRCKPGFQRNMKGRECADLNECLLFG-ICSHHCLNTRGSYKCVC 3869 Query: 366 ANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTD------GSNYSAIQKFA 419 ++ + + SC I+ G E + + +A+ TD NYS + Sbjct: 3870 DQNFQEKNN--SC-------------IAKGSEDQALYIANDTDILGFVYPFNYSGGHQQI 3914 Query: 420 GH----GTIRSIDFMHRNNKMFMSISDEHGD------PTGELSVSDNGLMRVLRENVIGV 469 H I +D ++ N + S G E +++GL + Sbjct: 3915 SHVEHNSRITGMDVHYQRNVIVWSTQFNPGGIFYKMIDAREKRQANSGL---ICPEFKRP 3971 Query: 470 SNVAVDWIGGNVFFTQKS------------PSPSAGISICTMSGMFCRRVIEGKEQGQSY 517 ++AVDW+ GNV++T S S I++ ++G C R++ G+ Y Sbjct: 3972 RDIAVDWVAGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNM-AGEPY 4030 Query: 518 RGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFG 577 + V+P RG++ W H I A MDG+ R+L+ L+ P+ L +D+ +Y+ Sbjct: 4031 -AIAVNPKRGMMYWTVIGDHSH-IEEAAMDGTLRRVLVQKNLQRPTGLTVDHFGERIYWA 4088 Query: 578 DVERQLIERVNID--TKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHS 635 D E +I V D + V G+ HP+ + F ++Y A + +VQ+ H Sbjct: 4089 DFELSIIGSVLYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGPKNGIFRVQKFG--HG 4146 Query: 636 SPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGY 695 S +V+ I V+H Q P NPCL+L C +LC++ P A C+CP+G Sbjct: 4147 SVEVLALGVDKTKSILVSHRYKQLNLP-NPCLDLSCDFLCLLNPSG-----ATCICPEG- 4199 Query: 696 THSVTENSCIPPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHR 755 + +C D+ +L+ + C+ + C NGG C + NE G Sbjct: 4200 -KYMMNGTC------HDD-----------SLLDDSCK--LTCENGGRC--ILNEKG---D 4234 Query: 756 IVCDCEGPYDGQYCE 770 + C C Y G CE Sbjct: 4235 LRCHCWPSYSGGRCE 4249
Score = 191 bits (486), Expect = 3e-47 Identities = 188/719 (26%), Positives = 290/719 (40%), Gaps = 109/719 (15%) Query: 28 NNSTCD----QAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDE-SGCSYAHHCSTSFMLC 82 +N TC QA +F CGNG RCIP W CD DC DE + C + + +C Sbjct: 918 SNQTCTARTCQADQFSCGNG--RCIPTAWLCDREDDCGDQTDEVASCEFPTCEPLTQFIC 975 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL 142 K+G C++N++ CD +DDC D SDE C ++ L +F Sbjct: 976 KSGRCISNKWHCDTDDDCGDRSDEVGCVHSCLDDQF------------------------ 1011 Query: 143 RCRSGQCIQPDLVCDGHQDCSGGDDE--VNCTRRGHEN----MQSSTDFHDDVHLVDPTF 196 RC SG+CI CDG DC DE +NCT+ + + + D + + + Sbjct: 1012 RCSSGRCIPGHWACDGDNDCGDFSDETHINCTKEEARSPAGCIGNEFQCRPDGNCIPDLW 1071 Query: 197 FANEDNKCRSGYT-----------------MCHSGDVCIPXXXXXXXXXXXXXXXXEKNC 239 + + C G C S CI E++C Sbjct: 1072 RCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCRSTGRCINNAWVCDGDVDCEDQSDEEDC 1131 Query: 240 QTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESK 299 + +L G Y C S VC+ CNG K+CP G DE Sbjct: 1132 -------DSFLCGPPK----------YPCANDTS---VCLQPEKLCNGRKDCPDGSDEGD 1171 Query: 300 HCSECARKR--CDHTCMNTP-HGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCED 356 C EC+ C + C P G C C EG++L D TCE D CA+H C CE Sbjct: 1172 LCDECSLNNGGCSNHCSVVPGRGIVCSCPEGHQLKKDNRTCEIVDYCASHLR-CSQVCEQ 1230 Query: 357 RLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQ 416 + C C G+ L TDG SC + + E ++ S+ E+R++ L +YS + Sbjct: 1231 QKHMVKCSCYEGWALGTDGESCT--SVDSFEAFIIFSIRHEIRRIDLHK----GDYSLL- 1283 Query: 417 KFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSD--NGLMRVLRENVIGVSNVAV 474 G ++DF + ++ + E G+LS S + + V+ + + V Sbjct: 1284 -VPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTV 1342 Query: 475 DWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDS 534 DWI GN+++ + I + + G +I G + R + + P G++ W D Sbjct: 1343 DWIAGNIYWIDSNLDQ---IEVSKLDGSLRATLIAGAMEHP--RAIALDPRYGILFWTDW 1397 Query: 535 YQKYHRIMMANMDGSQVR-ILLDNKLEV-PSALAIDYIRHDVYFGDVERQLIERVNIDTK 592 + RI A+M G+ + I D K P+ L +D+ + + D I D Sbjct: 1398 DANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFERRIVWTDARSDAIYSAFYDGT 1457 Query: 593 ERRVVISNG--VHHPYDMAYFNGFLYWADWGSESL-KVQEMTHHHSSPQVIHTFNRYPYG 649 +I + HP+ ++ + +YW DW + +L K + T + S VI + P+ Sbjct: 1458 NMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLAKANKWTGQNVS--VIQKTSAQPFD 1515 Query: 650 IAVNHSLYQTGPPSNPCLELE----CPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSC 704 + + H Q P NPC E C LC+I + +A C CP S + +C Sbjct: 1516 LQIYHPSRQPQAP-NPCAANEGRGPCSHLCLI----NHNRSAACACPHLMKLSSDKKTC 1569
Score = 191 bits (484), Expect = 5e-47 Identities = 178/706 (25%), Positives = 299/706 (42%), Gaps = 72/706 (10%) Query: 42 NGRLRCIPAEWQCDNVADCDKGRDESGCSY--AHHCSTSFMLCKNGLCVANEFKCDGEDD 99 N C+ W CD DC DE C H C ++ C +G C+ N + CDG+ D Sbjct: 2647 NSTSLCVLPSWICDGSNDCGDYSDELKCPVQNKHKCEENYFGCPSGRCILNTWVCDGQKD 2706 Query: 100 CRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPE-----------------CHPPRL 142 C DG DE HC+ + ++F S + +G + C Sbjct: 2707 CEDGLDELHCDSSCSWNQFACSVKKCISKHWICDGEDDCGDSLDESDSICGAVTCAADMF 2766 Query: 143 RCR-SGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANED 201 C+ S C+ +CDG +DC G DE++ N F + P F + Sbjct: 2767 SCQGSHACVPQHWLCDGERDCPDGSDELSSAGCAPNNTCDENAFMCHNKVCIPKQFVCDH 2826 Query: 202 NKC---------RSGYTMCHSGDV-CIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLS 251 + + GY C + C + AP S Sbjct: 2827 DDDCGDGSDEFLQCGYRQCGPEEFRCADGRCLVNTLWQCDGDFDCPDSSDEAPINPRCRS 2886 Query: 252 GQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESK-HCSECARKR-- 308 + HSC+++ + C G CIP + C+ +C G DE+ H +EC K+ Sbjct: 2887 AE----HSCNSS-FFMCKN-----GRCIPSDGLCDIRDDCGDGSDETNCHINECLSKKIS 2936 Query: 309 -CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCAN 367 C C + P +C C G++L DDG TC D DEC++ G C C + G++ C CA Sbjct: 2937 GCSQDCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSS-GFPCSQQCINTYGTYKCHCAE 2995 Query: 368 GYELETDG-HSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRS 426 GYE + D + C+ + + E +L ++ E+R++ TDGSNY+ +++ G + + Sbjct: 2996 GYETQPDNPNGCR--SLSDEEPFLILADQHEIRKIS----TDGSNYTLLKQ--GLNNVIA 3047 Query: 427 IDFMHRNNKMF-MSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQ 485 +DF +R ++ + S +G + ++ + + V N + +AVDWIG N+++ Sbjct: 3048 LDFDYREEFIYWIDSSRPNGSRINRMCLNGSDIKVV--HNTAVPNALAVDWIGKNLYW-- 3103 Query: 486 KSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMAN 545 S + I + ++G++ ++ + + R L + P G + WID + Y I Sbjct: 3104 -SDTEKRIIEVSKLNGLYPTVLVSKRLKFP--RDLSLDPRAGNLYWIDCCE-YPHIGRVG 3159 Query: 546 MDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHP 605 MDG+ ++++ K+ P AL IDY+ H +Y+ D IE N+D R V + + Sbjct: 3160 MDGTNQSVVIETKISRPMALTIDYVNHRLYWAD--ENHIEFSNMDGSHRHKVPNQDIPGV 3217 Query: 606 YDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNP 665 + F ++YW D ++SL T +I++++ I V HS Q + Sbjct: 3218 IALTLFEDYIYWTDGKTKSLSRVHKTSGADRLSLINSWHAIT-DIQVYHSYRQPDVSKHL 3276 Query: 666 CL--ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVT 709 C C LC++ P T C CP + + +C+ T Sbjct: 3277 CTVNNGGCSHLCLLGPGK----THTCACPTNFYLAADNRTCLSNCT 3318
Score = 137 bits (345), Expect = 7e-31 Identities = 95/350 (27%), Positives = 170/350 (48%), Gaps = 23/350 (6%) Query: 278 CIPMNATCNGIKECPLGDDESKHCSE----CARKRCDHTCMNTPHGARCICQEGYKLADD 333 C+ ++ CNG+ +CP G DE HC E C + C C + RC C++G+++A+D Sbjct: 90 CVHLSKLCNGVVDCPDGFDEGGHCQELLPSCQQLNCQFKCAMVRNATRCYCEDGFEVAED 149 Query: 334 GLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFIS 393 G +C+D+DEC+ +G +C C++ GS+AC C GY +++D SCK + T + + + Sbjct: 150 GRSCKDQDECSIYG-ICSQTCKNTYGSYACSCVEGYIMQSDNRSCKVKHEPTDKAPMLLI 208 Query: 394 LGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEH------GDP 447 E ++ + +GS + + A I ++DF++ + S E G Sbjct: 209 SSLETIEL---FYINGSKMTTLSS-ANRNEIHTLDFIYSEEMICWIESRESSNQLKCGQI 264 Query: 448 TGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRV 507 T ++D ++ L ++ V +A DW+ N++F S I +C +G C + Sbjct: 265 TKAGRLTDQRIINSL-QSFQNVEQMAFDWLTRNIYFVDHV---SDRIFVCNFNGSVCVTL 320 Query: 508 IEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAI 567 IE + + + P+ G + + D Y +I ++DG ++ +K E PSALA+ Sbjct: 321 IESELHNP--KAIAADPIAGKLFFTD-YGNVPKIERCDLDGMNRTRIVYSKAEQPSALAL 377 Query: 568 DYIRHDVYFGDVERQLIERVNIDTKERRVVISN-GVHHPYDMAYFNGFLY 616 D + VY+ D+ + V+ K R ++ V H Y + F +LY Sbjct: 378 DLVNRLVYWVDLYLDYVGVVDYQGKNRHTIVQGRQVKHLYGITVFEDYLY 427
Score = 94.0 bits (232), Expect = 9e-18 Identities = 102/383 (26%), Positives = 145/383 (37%), Gaps = 71/383 (18%) Query: 26 AVNNSTCDQ---AKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 A +N TC A +F C +CIP W+CD V DC G DE C C Sbjct: 3307 AADNRTCLSNCTASQFRCKTD--KCIPFWWKCDTVDDCGDGSDEPDDCPEFKCQPGRFQC 3364 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNI-LKSRFDGS-NPSAPTTFVGHNG------ 134 GLC F CDGE+DC D SDE +C+ ++ L +F + N + NG Sbjct: 3365 GTGLCALPAFICDGENDCGDNSDELNCDTHVCLAGQFKCTKNKKCIPVNLRCNGQDDCGD 3424 Query: 135 -------PE--CHPPRLRCRSGQ-CIQPDLVCDGHQDCSGGDDEVNCTRRG---HE---- 177 PE C P +C++ + CI VCD DC+ DE NC ++ HE Sbjct: 3425 EEDEKDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCK 3484 Query: 178 NMQSSTDFHDDVHLVDPTFFANEDN----KCRSGYTMCHSGDVCIPXXXXXXXXXXXXXX 233 N D + D + ++EDN C +C +GD C+ Sbjct: 3485 NNNCIPDHWRCDNQNDCSDNSDEDNCKPQTCTLKDFLCSNGD-CVSSRFWCDGEFDCADG 3543 Query: 234 XXEKNCQTNAPSEEEYLSG--------QADHMHSCS---------------AAGMYSCGT 270 EKNC+T+ ++ S + D C ++ Y C + Sbjct: 3544 SDEKNCETSCSKDQFQCSNGQCLSAKWKCDGHEDCKYGEDEKNCEPAFPVCSSSEYMCAS 3603 Query: 271 KGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARK--RCDHTCMNTPHGARCICQEGY 328 G C+ + CNG +C G DE EC +C + P R +C Y Sbjct: 3604 GG-----CLSASLKCNGEPDCVDGSDEMDCVIECKEDQFQCKNKAYCIP--IRWLCDGIY 3656 Query: 329 KLADDGLTCEDEDECATHGHLCQ 351 D DE+ C G +C+ Sbjct: 3657 DCVDG----SDEETCGRGGSICR 3675
Score = 85.5 bits (210), Expect = 3e-15 Identities = 72/289 (24%), Positives = 133/289 (46%), Gaps = 26/289 (8%) Query: 350 CQHFC--EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLG----GEVRQMPL 403 C H C + C+C G+ + +DG SCK P+ LF+ G G VR M L Sbjct: 486 CSHICLLSSSYKTRTCRCRTGFNMGSDGRSCK-----RPKNELFLFYGKGRPGIVRGMDL 540 Query: 404 ADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLR 463 I+ R++DF N ++ +D G + +L+ Sbjct: 541 NTKIADECMIPIENLVNP---RALDFHAEANYIYF--ADTTSFLIGRQKIDGTERETILK 595 Query: 464 ENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSY-RGLVV 522 +++ V +AVDWIG N+++T + ++ + + ++EG G S+ R +VV Sbjct: 596 DDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEG---GMSHPRAIVV 652 Query: 523 HPMRGLIIWIDSYQ-----KYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFG 577 P+ G + W D + RI A MDG ++ + +K+ P+ L +D+ +Y+ Sbjct: 653 DPVNGWMYWTDWKEDKIDDSVGRIEKAWMDGVNRQVFVTSKMLWPNGLTLDFHTSTLYWC 712 Query: 578 DVERQLIERVNIDTKERRVVISNG-VHHPYDMAYFNGFLYWADWGSESL 625 D IE+V ++ R+VV S ++HP+ +++ +++W D+ + S+ Sbjct: 713 DAYYDHIEKVFLNGTHRKVVYSGKELNHPFGLSHHGNYVFWTDYMNGSI 761
Score = 84.3 bits (207), Expect = 7e-15 Identities = 77/290 (26%), Positives = 133/290 (45%), Gaps = 30/290 (10%) Query: 338 EDEDECATHGHLCQHFC-EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGG 396 + + C + C C + C C GY L+ + SC+ E +L S+ Sbjct: 1833 QGSNSCQVNNGGCSQLCLPTSETTRTCMCTVGYYLQKNRMSCQ-----GIESFLMYSVHE 1887 Query: 397 EVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMS------ISDEHGDPTGE 450 +R +PL A+ +G IDF N+ ++ + IS D T + Sbjct: 1888 GIRGIPL---EPRDKVDALMPISGAAFAVGIDFHAENDTIYWTDMGLNKISRAKRDQTWK 1944 Query: 451 LSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEG 510 V NGL R V +AVDWI GN+++T + I + ++G F R VI Sbjct: 1945 EDVVTNGLGR--------VEGIAVDWIAGNIYWTDHGFNL---IEVARLNGSF-RYVIIS 1992 Query: 511 KEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYI 570 + Q R + VHP +G + W + + + I A +DGS+ +++ + P+ ++IDY Sbjct: 1993 QGLDQP-RSIAVHPEKGFLFWTE-WGQVPCIGKARLDGSEKVMIVSVGITWPNGISIDYE 2050 Query: 571 RHDVYFGDVERQLIERVNIDTKERRVVISNGVH-HPYDMAYFNGFLYWAD 619 + +Y+ D IER+++DT R V+ +G + + +A F ++YW+D Sbjct: 2051 ENKLYWCDARSDKIERIDLDTGANREVLLSGSNVDLFSVAVFGAYIYWSD 2100
Score = 72.4 bits (176), Expect = 3e-11 Identities = 89/362 (24%), Positives = 145/362 (40%), Gaps = 34/362 (9%) Query: 350 CQHFCE-DRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM----PLA 404 C H C + S AC C + +L +D +C YE + +L + E+R + P Sbjct: 1540 CSHLCLINHNRSAACACPHLMKLSSDKKTC-YEM----KKFLLYARRSEIRGVDIDNPYV 1594 Query: 405 DFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRE 464 +F I A IDF +++ +D ++ GL V+ Sbjct: 1595 NFITAFTVPDIDDVA------VIDFDASEERLYW--TDIKTQTITRAFINGTGLETVISR 1646 Query: 465 NVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHP 524 ++ + +AVDW+ N+++ S I++ + G +I G ++ Q L HP Sbjct: 1647 DIQSIRGLAVDWVSRNLYWIS-SEFDETQINVARLDGSLKTSIIHGIDKPQC---LAAHP 1702 Query: 525 MRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLI 584 +RG + W D + I MANMDGS +IL N+ E P L+IDY+ + +Y+ I Sbjct: 1703 VRGKLYWTDG----NTINMANMDGSNSKILFQNQKE-PVGLSIDYVENKLYWISSGNGTI 1757 Query: 585 ERVNIDTKERRVV--ISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHT 642 R N+D V+ + + + + L+WAD L +P ++ Sbjct: 1758 NRCNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCN-KRDGRNPSILRN 1816 Query: 643 FNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTEN 702 + V Q G S C LC +P S+ T C+C GY Sbjct: 1817 KTSGVVHMKVYDKEAQQGSNSCQVNNGGCSQLC--LPTSE--TTRTCMCTVGYYLQKNRM 1872 Query: 703 SC 704 SC Sbjct: 1873 SC 1874
Score = 68.2 bits (165), Expect = 5e-10 Identities = 35/82 (42%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Query: 36 KEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGC-----SYAHHCSTSFMLCKNGLCVAN 90 +EF C +GR + WQCD DC DE+ S H C++SF +CKNG C+ + Sbjct: 2848 EEFRCADGRC-LVNTLWQCDGDFDCPDSSDEAPINPRCRSAEHSCNSSFFMCKNGRCIPS 2906 Query: 91 EFKCDGEDDCRDGSDEQHCEYN 112 + CD DDC DGSDE +C N Sbjct: 2907 DGLCDIRDDCGDGSDETNCHIN 2928
Score = 64.7 bits (156), Expect = 6e-09 Identities = 75/295 (25%), Positives = 130/295 (44%), Gaps = 25/295 (8%) Query: 343 CATHGHLCQHFCEDRLGS-FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 CA CQ C R S C CA+GY L DG +C EGYL S ++ + Sbjct: 2147 CAKENGGCQQLCLYRGNSRRTCACAHGY-LAGDGVTCLRH-----EGYLLYSGRTILKSI 2200 Query: 402 PLADFTDGSNYSAIQKFAGHGTIRSI-----DFMHR---NNKMFMSISDEHGDPTGELS- 452 L+D T+ + S ++ + ++I D+ R N++F SD H G + Sbjct: 2201 HLSDETNLN--SPVRPYENPNYFKNIIALAFDYNQRREGTNRIFY--SDAH---FGNIQL 2253 Query: 453 VSDNGLMR-VLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISI-CTMSGMFCRRVIEG 510 + DN R V+ ENV V +A +++T S S ++ T G R + Sbjct: 2254 IKDNWEDRQVIVENVGSVEGLAYHRAWDTLYWTSSSTSSITRHTVDQTRPGAIDREAVIT 2313 Query: 511 KEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYI 570 + L + + L+ W + +++ IM A + G +++ + P+ L ID+ Sbjct: 2314 MSEDDHPHVLALDECQNLMFWTNWNEQHPSIMRATLTGKNAHVVVSTDILTPNGLTIDHR 2373 Query: 571 RHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL 625 +YF D IER D +R V++ +G +A ++ +++W+DWG ++ Sbjct: 2374 AEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDSYIFWSDWGRRAI 2428
>gi|16768036|gb|AAL28237.1| GH12891p [Drosophila melanogaster] Length = 1952 Score = 198 bits (504), Expect = 3e-49 Identities = 203/785 (25%), Positives = 309/785 (39%), Gaps = 120/785 (15%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGC---SYAHHCSTSFMLCKN 84 N C+ +F CGN RCIP +W CD DC DE+ CS S C N Sbjct: 1048 NCPKCNPETDFKCGNN--RCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGN 1105 Query: 85 GLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRC 144 G C+++ ++CD EDDC D SDE HCE G +C +C Sbjct: 1106 GKCISSRWQCDHEDDCGDNSDEMHCE-----------------------GYQCKNGTFQC 1142 Query: 145 RSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKC 204 SG CI CDG +DC DEV C R F + + F N +N C Sbjct: 1143 ASGHCIASYFRCDGDRDCRDMSDEVGCPPR----------FPGGRYCPESRFQCN-NNLC 1191 Query: 205 RSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAP------------------SE 246 S +C D C + Q + S+ Sbjct: 1192 VSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQCSNERCVARYQICDGVDNCGDGSD 1251 Query: 247 EEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE-----SKHC 301 E ++ A C Y C K CI + C+ +C DE + C Sbjct: 1252 ENNMTLCASKQKPCDLYTQYQCANKH-----CIERSQVCDFSDDCGDASDELGCHHTSSC 1306 Query: 302 SECARKRCDHTCMN-TPHGARCICQEGYKL-ADDGLTCEDEDECATHGHLCQHFCEDRLG 359 SE R C C N T G C C GY + AD+ C D DEC T H C H C + G Sbjct: 1307 SEANRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDVDECLTRQHTCSHQCHNLNG 1366 Query: 360 SFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKF- 418 +++C C G+ L TDG S A LF++ G E+R G N+ ++F Sbjct: 1367 TYSCSCREGFHL-TDGASGVCRAEKEDVILLFVN-GQEIR---------GLNWHKSEEFA 1415 Query: 419 --AGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRV---LRENVIGVSN-- 471 A I ++D+ + +F + S + + + +G ++ N+ G S Sbjct: 1416 VIAAEKRIEALDYDAQQQIVFWADSYDKTIKRSYMVNAIDGRAKIGFAQDLNMKGGSKPT 1475 Query: 472 -VAVDWIGGNVFFTQ---KSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRG 527 VAVDW+ N+++T+ P + + G + R ++ + + + V+P G Sbjct: 1476 AVAVDWLASNLYWTEMDRTGSKPRGRVMVAKTDGRYRRSIVNAGLEVPT--SIAVNPQLG 1533 Query: 528 LIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIR-HDVYFGDVERQLIER 586 I W D+ +I ++ MDGS+ R L+ + P+ L IDY + H +Y+ D + IE Sbjct: 1534 RIYWSDA-GSAPKIEVSWMDGSKRRPLITEMIRHPAGLTIDYSQDHIIYWVDTKLNAIES 1592 Query: 587 VNIDTKERRVVI-SNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNR 645 + D R+ ++ + + HP + F ++W + L V++ V+H + Sbjct: 1593 MRADGSRRKAIVRGDQLRHPVSLDLFESNMFWMTRDTGEL-VRQDKFGRGVQVVLHRYIV 1651 Query: 646 YPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCI 705 P G+ V H NPC C LC++VP +C CPD + S Sbjct: 1652 NPSGLKVYHDKRYNTSLPNPCDNSTCSHLCLLVPGGH-----RCACPDASGPPPSHRSTA 1706 Query: 706 PPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYD 765 + E+ I C NGG C+E + G ++C+C + Sbjct: 1707 EVICNAAAEHPRPAPRI------------CPCQNGGLCKE--DAQG---ELLCECRTQFV 1749 Query: 766 GQYCE 770 G++CE Sbjct: 1750 GEHCE 1754
Score = 170 bits (430), Expect = 1e-40 Identities = 190/722 (26%), Positives = 293/722 (40%), Gaps = 91/722 (12%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESG--C-SYAHHCSTSFMLCKNGLC 87 TC F C N RCIPA W CD DC G DE C S C C NG C Sbjct: 174 TC-PTNSFRCPNH--RCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNC 230 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 + + CDG++DC D SDE + + + + T F C + R+ Sbjct: 231 IPRIYICDGDNDCLDNSDEDN------RHQCNDRKCDEETEFT------CVENKSWQRA- 277 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHD--DVHLVDPTFFANEDNKCR 205 QCI +CDG DC G DE D + ++ + + DN C Sbjct: 278 QCIPKKWICDGDPDCVDGADENTTLHNCATQQPCGEDMFTCGNGRCINKGWICDHDNDCG 337 Query: 206 SGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAA-- 263 G G C Q+ E++ DH A Sbjct: 338 DG---TDEGKFCNSKYKTCSAQEFTCQNFKCIRNQSRCDGEDDC----GDHSDEVGCAKE 390 Query: 264 ------GMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCS--ECAR---KRCDHT 312 G ++C G CI N CN +C DE HC+ ECA+ +C H Sbjct: 391 NITCPQGQFACTN-----GQCIDYNLVCNKYPDCADESDEPAHCNVDECAKVEINQCGHK 445 Query: 313 CMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANG-YEL 371 C++T G C C EGYKL DG C D DEC C C + G F CKC YE Sbjct: 446 CVDTLTGYYCDCNEGYKLLADGKACADVDECLEQPGACSQHCSNTPGGFYCKCDETYYER 505 Query: 372 ETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMH 431 + D H+CK + P +L + VR M + DG Y+ + + + ++DF Sbjct: 506 QNDEHTCKRKDKIPP--WLIFTNKYYVRNMSV----DGHQYNLMHQ--DLMNVVALDFDI 557 Query: 432 RNNKMFMS-------ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFT 484 R M+ ++G+ E+ V+R + G+ +A+DW+G +++ Sbjct: 558 REEYMYFCDVTAKTIFRAKYGEADDEMPPEREA---VIRHDSHGLEGIAIDWVGRKLYWL 614 Query: 485 QKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMA 544 + S + + + G + + G R +VVHP G ++ S+ I Sbjct: 615 DRH---SKNLDVSELDGSKRKTLRSGVVDP---RAIVVHPGIGY-LYFTSWHLQAYIAKM 667 Query: 545 NMDGSQVRILL--DNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG- 601 MDGS +L ++ + P+AL+IDY +Y+ D I +++ + R V+S Sbjct: 668 GMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHTVLSGSK 727 Query: 602 VHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGP 661 V H + ++ F+ ++YW+DW +++ V+ H ++ V+ PY + +NH L Q P Sbjct: 728 VPHVFALSLFDDYIYWSDWNLKAI-VRANKFHGANYTVLRNTTHRPYDLHINHPLRQL-P 785 Query: 662 PSNPCLELE--CPWLCVIV--PKSDFIMTA----------KCVCPDGYTHSVTENSCIPP 707 +NPC C LC+I P+S ++ KC CP+ + + +C+ Sbjct: 786 YTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFYLARDMKTCVAN 845 Query: 708 VT 709 T Sbjct: 846 CT 847
Score = 78.6 bits (192), Expect = 4e-13 Identities = 87/353 (24%), Positives = 130/353 (36%), Gaps = 82/353 (23%) Query: 40 CGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDD 99 CG +CIP W+CD DC G DE HC CKN C + CDG DD Sbjct: 853 CGGRDEKCIPWFWKCDGEKDCKDGSDEPATCAPRHCRAGTFQCKNTNCTPSATICDGVDD 912 Query: 100 CRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQCIQPDLVCDG 158 C D SDEQ+C+ C +C+ SG+CI CDG Sbjct: 913 CGDRSDEQNCDL------------------------PCPLSDFKCKSSGRCILDSWRCDG 948 Query: 159 HQDCSGGDDE--VNCTRRGHENMQSST-------------DFHDDV--HLVDPTFFANED 201 DC G DE C +R + + DF +D +P + + Sbjct: 949 DADCKDGSDEDPAVCFKRTCDPKTEFSCKNGRCIPQLWMCDFDNDCGDDSDEPAYMCRQR 1008 Query: 202 NKCRSGYTMC--HSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHS 259 N C +G+ C S CIP + +C+ N+ E + Sbjct: 1009 N-CTTGWQRCPGQSNYRCIP---------KWLFCDGKDDCRDNSDELPE-------NCPK 1051 Query: 260 CSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTPHG 319 C+ + CG CIP C+ +C DE++ + + C + +G Sbjct: 1052 CNPETDFKCGNNR-----CIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNG 1106 Query: 320 ARCICQEGYKLADDGLTCEDEDECATHG---HLCQHFCEDRLGSFACKCANGY 369 +CI C+ ED+C + H + C++ G+F +CA+G+ Sbjct: 1107 -KCISSR--------WQCDHEDDCGDNSDEMHCEGYQCKN--GTF--QCASGH 1146
Score = 74.7 bits (182), Expect = 5e-12 Identities = 105/417 (25%), Positives = 156/417 (37%), Gaps = 76/417 (18%) Query: 26 AVNNSTCDQAKEFDCGNGRLRCIPAEW--QCDNVADCDKGRDESGCSYAHHCSTSFMLCK 83 A N+TC +A +F C NG RCI W D+ + D + C+Y H CS + C Sbjct: 3 APRNNTC-EASKFYCKNG--RCISRMWSCDGDDDCGDNSDEDPNYCAY-HSCSPNEFRCN 58 Query: 84 NGLCVANEFKCDGEDDCRDGSDEQHCEY-NILKSRFDGSNPSAPTTFVGHNG-------- 134 NG C+ +KCD E+DC+DGSDE C Y + F +N NG Sbjct: 59 NGRCIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCANGRCIPQAQVCNGVNDCKDNA 118 Query: 135 ------------PECHPPRLRC-RSGQCIQPDLVCDGHQDCSGGDDE--VNCTRR----- 174 C L+C ++ C++P +CDG DC DE ++C +R Sbjct: 119 TSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCPTN 178 Query: 175 -----GHENMQSS-----TDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXX 224 H + ++ D D P + +E C C +G+ CIP Sbjct: 179 SFRCPNHRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGN-CIP----- 232 Query: 225 XXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSC-GTKGSEIGVCIPMNA 283 + +C N+ + + C ++C K + CIP Sbjct: 233 ----RIYICDGDNDCLDNSDEDNRHQCND----RKCDEETEFTCVENKSWQRAQCIPKKW 284 Query: 284 TCNGIKECPLGDDESKHCSECARKRCDHTCMNTPHGARCI-----------CQEGYKLAD 332 C+G +C G DE+ CA ++ M T RCI C +G D Sbjct: 285 ICDGDPDCVDGADENTTLHNCATQQPCGEDMFTCGNGRCINKGWICDHDNDCGDG---TD 341 Query: 333 DGLTCEDE-DECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEG 388 +G C + C+ CQ+F R S C + +D C E T P+G Sbjct: 342 EGKFCNSKYKTCSAQEFTCQNFKCIRNQS-RCDGEDDCGDHSDEVGCAKENITCPQG 397
>gi|9055270|ref|NP_061027.1| low density lipoprotein-related protein 1B (deleted in tumors); low density lipoprotein receptor related protein-deleted in tumor [Homo sapiens] gi|7861733|gb|AAF70379.1|AF176832_1 low density lipoprotein receptor related protein-deleted in tumor [Homo sapiens] Length = 4599 Score = 195 bits (496), Expect = 2e-48 Identities = 183/706 (25%), Positives = 301/706 (42%), Gaps = 79/706 (11%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 + P N C++ F C +G RCI W CD DC+ GRDE C + CS + C Sbjct: 2673 KCPVQNKHKCEE-NYFSCPSG--RCILNTWICDGQKDCEDGRDEFHCDSS--CSWNQFAC 2727 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL 142 C++ + CDGEDDC DG DE G+ A F C R Sbjct: 2728 SAQKCISKHWICDGEDDCGDGLDES--------DSICGAITCAADMF------SCQGSR- 2772 Query: 143 RCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFA---- 198 C+ +CDG +DC G DE++ N F + P F Sbjct: 2773 -----ACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHD 2827 Query: 199 -------NEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLS 251 +E +C GY C + + + +C + S+E L+ Sbjct: 2828 DDCGDGSDESPQC--GYRQCGTEE--FSCADGRCLLNTQWQCDGDFDCPDH--SDEAPLN 2881 Query: 252 GQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESK-HCSECARKR-- 308 + + + C G CIP C+ +C G DE H +EC K+ Sbjct: 2882 PKCKSAEQSCNSSFFMCKN-----GRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVS 2936 Query: 309 -CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCAN 367 C C + P +C C G++L DDG TC D DEC++ G C C + G++ C C + Sbjct: 2937 GCSQDCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSS-GFPCSQQCINTYGTYKCLCTD 2995 Query: 368 GYELETDG-HSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRS 426 GYE++ D + CK + + E +L ++ E+R++ TDGSNY+ +++ G + + Sbjct: 2996 GYEIQPDNPNGCK--SLSDEEPFLILADHHEIRKIS----TDGSNYTLLKQ--GLNNVIA 3047 Query: 427 IDFMHRNNKMF-MSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQ 485 IDF +R ++ + S +G + ++ + + V N + +AVDWIG N+++ Sbjct: 3048 IDFDYREEFIYWIDSSRPNGSRINRMCLNGSDIKVV--HNTAVPNALAVDWIGKNLYW-- 3103 Query: 486 KSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMAN 545 S + I + ++G++ ++ + + R L + P G + WID + Y I Sbjct: 3104 -SDTEKRIIEVSKLNGLYPTILVSKRLKFP--RDLSLDPQAGYLYWIDCCE-YPHIGRVG 3159 Query: 546 MDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHP 605 MDG+ ++++ K+ P AL IDY+ +Y+ D IE N+D R V + + Sbjct: 3160 MDGTNQSVVIETKISRPMALTIDYVNRRLYWAD--ENHIEFSNMDGSHRHKVPNQDIPGV 3217 Query: 606 YDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNP 665 + F ++YW D ++SL T +I++++ I V HS Q + Sbjct: 3218 IALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYSWHAIT-DIQVYHSYRQPDVSKHL 3276 Query: 666 CL--ELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSCIPPVT 709 C+ C LC++ P T C CP + + +C+ T Sbjct: 3277 CMINNGGCSHLCLLAPGK----THTCACPTNFYLAADNRTCLSNCT 3318
Score = 195 bits (495), Expect = 3e-48 Identities = 205/785 (26%), Positives = 324/785 (41%), Gaps = 125/785 (15%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAH-HCSTSFMLCKNGL 86 N T +F C NG +CIPA+W+CD DC G DE C A CS+ +C + Sbjct: 3548 NCETSCSKDQFRCSNG--QCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDG 3605 Query: 87 CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRS 146 C++ KC+GE DC DGSDE C EC + RC++ Sbjct: 3606 CISASLKCNGEYDCADGSDEMDCV------------------------TECKEDQFRCKN 3641 Query: 147 -GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCR 205 CI +CDG DC G DE NC R G N+ + +F + L F+ D + Sbjct: 3642 KAHCIPIRWLCDGIHDCVDGSDEENCERGG--NICRADEFLCNNSLCKLHFWVC-DGEDD 3698 Query: 206 SGYTMCHSGDVCI----PXXXXXXXXXXXXXXXXEKNC----QTNAPSEEEYLSGQADHM 257 G + D+C+ P E+ C + S+E++ G+ + Sbjct: 3699 CGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGKLTYK 3758 Query: 258 HSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE-------SKHCSECARKRC- 309 ++C K CIPM+ C+ + +C G DE +++ E C Sbjct: 3759 ARPCKKDEFACSNKK-----CIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCG 3813 Query: 310 -DHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANG 368 D C C C+ G++ CED +EC G C H C + GS+ C C Sbjct: 3814 DDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLVFG-TCSHQCINVEGSYKCVCDQN 3872 Query: 369 YELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSID 428 ++ + +C E + + L+I+ ++ + F ++ I + I +D Sbjct: 3873 FQERNN--TCIAEGSE--DQVLYIANDTDILGF-IYPFNYSGDHQQISHIEHNSRITGMD 3927 Query: 429 FMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGV--------SNVAVDWIGGN 480 ++ + M I +P G +G R R+ G+ ++AVDW+ GN Sbjct: 3928 VYYQRD---MIIWSTQFNPGGIFYKRIHG--REKRQANSGLICPEFKRPRDIAVDWVAGN 3982 Query: 481 VFFTQKS------------PSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGL 528 +++T S S I++ ++G C R++ G+ Y + V+P RG+ Sbjct: 3983 IYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNM-AGEPY-AIAVNPKRGM 4040 Query: 529 IIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVN 588 + W H I A MDG+ RIL+ L+ P+ LA+DY +Y+ D E +I V Sbjct: 4041 MYWTVVGDHSH-IEEAAMDGTLRRILVQKNLQRPTGLAVDYFSERIYWADFELSIIGSVL 4099 Query: 589 ID--TKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRY 646 D V G+ HP+ + F ++Y A + +VQ+ H S + + Sbjct: 4100 YDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGPKNGVFRVQKFG--HGSVEYLALNIDK 4157 Query: 647 PYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDG-YTHSVTENSCI 705 G+ ++H Q P NPCL+L C +LC++ P A CVCP+G Y + T N Sbjct: 4158 TKGVLISHRYKQLDLP-NPCLDLACEFLCLLNPSG-----ATCVCPEGKYLINGTCND-- 4209 Query: 706 PPVTIEDEENLEKLSHIGSALMAEYCEAGVACMNGGACRELQNEHGRAHRIVCDCEGPYD 765 +L+ + C+ + C NGG C + NE G + C C Y Sbjct: 4210 ------------------DSLLDDSCK--LTCENGGRC--ILNEKG---DLRCHCWPSYS 4244 Query: 766 GQYCE 770 G+ CE Sbjct: 4245 GERCE 4249
Score = 164 bits (414), Expect = 8e-39 Identities = 187/738 (25%), Positives = 283/738 (38%), Gaps = 147/738 (19%) Query: 28 NNSTCD----QAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDE-SGCSY----------- 71 +N TC Q +F CGNG RCIP W CD DC DE + C + Sbjct: 918 SNQTCTARTCQVDQFSCGNG--RCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVC 975 Query: 72 ---------------------------AHHCSTSFMLCKNGLCVANEFKCDGEDDCRDGS 104 H C + C +G C+ + CDG++DC D S Sbjct: 976 KSGRCISSKWHCDSDDDCGDGSDEVGCVHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFS 1035 Query: 105 DEQHCEYNILKSRFDGSNPSAPTTFVGHNGPE--CHPPRLRCRSGQCIQPDL-VCDGHQD 161 DE + N K G NG E CHP G C+ PDL CDG +D Sbjct: 1036 DE--AQINCTKEEIHSP--------AGCNGNEFQCHP------DGNCV-PDLWRCDGEKD 1078 Query: 162 CSGGDDEVNCTRRGHENMQSSTDFHDDVHLVD-PTFFANEDNKCRSGYTMCHSGDVCIPX 220 C G DE C + + L D T F+ C S CI Sbjct: 1079 CEDGSDEKGC--------------NGTIRLCDHKTKFS------------CWSTGRCINK 1112 Query: 221 XXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIP 280 E +C + +L G H C+ ++ VC+ Sbjct: 1113 AWVCDGDIDCEDQSDEDDC-------DSFLCGPPK--HPCA-----------NDTSVCLQ 1152 Query: 281 MNATCNGIKECPLGDDESKHCSECARKR--CDHTCMNTP-HGARCICQEGYKLADDGLTC 337 CNG K+CP G DE C EC+ C + C P G C C EG +L D TC Sbjct: 1153 PEKLCNGKKDCPDGSDEGYLCDECSLNNGGCSNHCSVVPGRGIVCSCPEGLQLNKDNKTC 1212 Query: 338 EDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGE 397 E D C+ H C CE + C C G++L+ DG SC + E ++ S+ E Sbjct: 1213 EIVDYCSNHLK-CSQVCEQHKHTVKCSCYEGWKLDVDGESCT--SVDPFEAFIIFSIRHE 1269 Query: 398 VRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSD-- 455 +R++ L +YS + G ++DF + ++ + E G+LS S Sbjct: 1270 IRRIDLHK----RDYSLL--VPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGV 1323 Query: 456 NGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQ 515 + + V+ + + VDWI GN+++ + I + + G +I G + Sbjct: 1324 SAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLDQ---IEVAKLDGSLRTTLIAGAMEHP 1380 Query: 516 SYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVR-ILLDNKLEV-PSALAIDYIRHD 573 R + + P G++ W D + RI A+M G+ + I D K P+ L +D+ Sbjct: 1381 --RAIALDPRYGILFWTDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKR 1438 Query: 574 VYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNGFLYWADWGSESL-KVQEM 630 + + D I D +I + HP+ ++ + +YW DW + +L K + Sbjct: 1439 IVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKW 1498 Query: 631 THHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE----CPWLCVIVPKSDFIMT 686 T + S VI + P+ + + H Q P NPC + C +C+I + + Sbjct: 1499 TGQNVS--VIQKTSAQPFDLQIYHPSRQPQAP-NPCAANDGKGPCSHMCLI----NHNRS 1551 Query: 687 AKCVCPDGYTHSVTENSC 704 A C CP S + +C Sbjct: 1552 AACACPHLMKLSSDKKTC 1569
Score = 135 bits (341), Expect = 2e-30 Identities = 112/448 (25%), Positives = 204/448 (45%), Gaps = 36/448 (8%) Query: 278 CIPMNATCNGIKECPLGDDESKHCSE----CARKRCDHTCMNTPHGARCICQEGYKLADD 333 C+ ++ CNG+ +CP G DE HC E C + C + C + RC C++G+++ +D Sbjct: 90 CVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEITED 149 Query: 334 GLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFIS 393 G +C+D+DECA +G C C + GS+ C C GY ++ D SCK + T + + Sbjct: 150 GRSCKDQDECAVYG-TCSQTCRNTHGSYTCSCVEGYLMQPDNRSCKAKIEPTDRPPILLI 208 Query: 394 LGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSV 453 E ++ + +GS + + G+ I ++DF++ + + S E + + + Sbjct: 209 ANFETIEV---FYLNGSKMATLSSVNGN-EIHTLDFIYNEDMICWIESRESSNQLKCIQI 264 Query: 454 SD-NGLMRVLRENVI----GVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVI 508 + GL N++ V +A+DW+ N++F I +C +G C +I Sbjct: 265 TKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFVDHV---GDRIFVCNSNGSVCVTLI 321 Query: 509 EGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAID 568 + + + + + V P+ G + + D Y ++ +MDG ++D+K E P+ALA+D Sbjct: 322 D--LELHNPKAIAVDPIAGKLFFTD-YGNVAKVERCDMDGMNRTRIIDSKTEQPAALALD 378 Query: 569 YIRHDVYFGDVERQLIERVNIDTKERRVVISN-GVHHPYDMAYFNGFLYWADWGSESLKV 627 + VY+ D+ + V+ K R VI V H Y + F +LY + S++ + Sbjct: 379 LVNKLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQVRHLYGITVFEDYLYATN--SDNYNI 436 Query: 628 QEMTHHHSSPQVIHTFNRY--PYGIAVNHSLYQTGPPSNPC------LELECPWLCVIVP 679 + + + IH+ + +GI + Q S+ C + C +C++ Sbjct: 437 VRINRFNGTD--IHSLIKIENAWGIRIYQKRTQPTVRSHACEVDPYGMPGGCSHICLL-- 492 Query: 680 KSDFIMTAKCVCPDGYTHSVTENSCIPP 707 S T C C G+ SC P Sbjct: 493 -SSSYKTRTCRCRTGFNLGSDGRSCKRP 519
Score = 96.7 bits (239), Expect = 1e-18 Identities = 98/375 (26%), Positives = 136/375 (36%), Gaps = 77/375 (20%) Query: 26 AVNNSTCDQ---AKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 A +N TC A +F C +CIP W+CD V DC G DE C C Sbjct: 3307 AADNRTCLSNCTASQFRCKTD--KCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPGRFQC 3364 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL 142 GLC F CDGE+DC D SDE +C+ ++ C + Sbjct: 3365 GTGLCALPAFICDGENDCGDNSDELNCDTHV-----------------------CLSGQF 3401 Query: 143 RCRSGQ-CIQPDLVCDGHQDCSGGDDEVNCTRR--GHENMQSSTDFH---------DDVH 190 +C Q CI +L C+G DC +DE +C + Q T H +D Sbjct: 3402 KCTKNQKCIPVNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPD 3461 Query: 191 LVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYL 250 D + AN D K + + CIP E+NC+ + +++L Sbjct: 3462 CADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFL 3521 Query: 251 SGQADHMHS----------CSAAGMYSCGTKGSEI------GVCIPMNATCNGIKECPLG 294 D + S + +C T S+ G CIP C+G ++C G Sbjct: 3522 CANGDCVSSRFWCDGDFDCADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYG 3581 Query: 295 DDESKHCSECARKRCDHTCMNTPHGARCICQEGYKLADDG-----LTCEDEDECATHGHL 349 +DE K C+ P C +E Y A DG L C E +CA Sbjct: 3582 EDE---------KSCE------PASPTCSSRE-YICASDGCISASLKCNGEYDCADGSDE 3625 Query: 350 CQHFCEDRLGSFACK 364 E + F CK Sbjct: 3626 MDCVTECKEDQFRCK 3640
Score = 88.6 bits (218), Expect = 4e-16 Identities = 72/288 (25%), Positives = 133/288 (46%), Gaps = 24/288 (8%) Query: 350 CQHFC--EDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLG----GEVRQMPL 403 C H C + C+C G+ L +DG SCK P+ LF+ G G VR M L Sbjct: 486 CSHICLLSSSYKTRTCRCRTGFNLGSDGRSCK-----RPKNELFLFYGKGRPGIVRGMDL 540 Query: 404 ADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLR 463 I+ R++DF N ++ +D G + +L+ Sbjct: 541 NTKIADEYMIPIENLVNP---RALDFHAETNYIYF--ADTTSFLIGRQKIDGTERETILK 595 Query: 464 ENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVH 523 +++ V +AVDWIG N+++T + ++ + + ++EG+ RG+VV Sbjct: 596 DDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMSHP--RGIVVD 653 Query: 524 PMRGLIIWIDSYQ-----KYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGD 578 P+ G + W D + RI A MDG +I + +K+ P+ L +D+ + +Y+ D Sbjct: 654 PVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFHTNTLYWCD 713 Query: 579 VERQLIERVNIDTKERRVVISN-GVHHPYDMAYFNGFLYWADWGSESL 625 IE+V ++ R++V S ++HP+ +++ +++W D+ + S+ Sbjct: 714 AYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFWTDYMNGSI 761
Score = 85.5 bits (210), Expect = 3e-15 Identities = 75/264 (28%), Positives = 125/264 (47%), Gaps = 29/264 (10%) Query: 363 CKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHG 422 C C GY L+ + SC+ E +L S+ +R +PL A+ +G Sbjct: 1859 CMCTVGYYLQKNRMSCQ-----GIESFLMYSVHEGIRGIPL---EPSDKMDALMPISGTS 1910 Query: 423 TIRSIDFMHRNNKM------FMSISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDW 476 IDF N+ + F IS D T + + NGL R V +AVDW Sbjct: 1911 FAVGIDFHAENDTIYWTDMGFNKISRAKRDQTWKEDIITNGLGR--------VEGIAVDW 1962 Query: 477 IGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQ 536 I GN+++T + I + ++G F R VI + Q R + VHP +GL+ W + + Sbjct: 1963 IAGNIYWTDHGFNL---IEVARLNGSF-RYVIISQGLDQP-RSIAVHPEKGLLFWTE-WG 2016 Query: 537 KYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDT-KERR 595 + I A +DGS+ +L+ + P+ ++IDY + +Y+ D IER++++T R Sbjct: 2017 QMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLETGGNRE 2076 Query: 596 VVISNGVHHPYDMAYFNGFLYWAD 619 +V+S + +A F ++YW+D Sbjct: 2077 MVLSGSNVDMFSVAVFGAYIYWSD 2100
Score = 80.1 bits (196), Expect = 1e-13 Identities = 93/361 (25%), Positives = 127/361 (35%), Gaps = 81/361 (22%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHH-CSTSFMLCKNGLC 87 NS+C+ EF+CGNG CI + CD + C DE + C F C N C Sbjct: 2507 NSSCNAYSEFECGNG--ECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRC 2564 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 + + CDGE+DC D SDE C+ + C RC G Sbjct: 2565 IPHGKLCDGENDCGDNSDELDCKVST-----------------------CATVEFRCADG 2601 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSG 207 CI C+ + DC+ DE NC D T F K +G Sbjct: 2602 TCIPRSARCNQNIDCADASDEKNCNN------------------TDCTHFYKLGVKT-TG 2642 Query: 208 YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC--QTNAPSEEEYLS-------------- 251 + C+S +C+ E C Q EE Y S Sbjct: 2643 FIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWICD 2702 Query: 252 GQAD--------HMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSE 303 GQ D H S + ++C + CI + C+G +C G DES S Sbjct: 2703 GQKDCEDGRDEFHCDSSCSWNQFACSAQK-----CISKHWICDGEDDCGDGLDESD--SI 2755 Query: 304 CARKRCDHTCMNTPHGARCICQEGYKLADDGLTCED-EDECATHGHLCQHFCEDRLGSFA 362 C C M + G+R C + L D C D DE +T G + C++ +F Sbjct: 2756 CGAITCAAD-MFSCQGSRA-CVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDE--NAFM 2811 Query: 363 C 363 C Sbjct: 2812 C 2812
Score = 72.0 bits (175), Expect = 4e-11 Identities = 88/360 (24%), Positives = 147/360 (40%), Gaps = 30/360 (8%) Query: 350 CQHFCE-DRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTD 408 C H C + S AC C + +L +D +C YE + +L + E+R + + D Sbjct: 1540 CSHMCLINHNRSAACACPHLMKLSSDKKTC-YEM----KKFLLYARRSEIRGVDI----D 1590 Query: 409 GSNYSAIQKFA--GHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENV 466 ++ I F + IDF +++ +D ++ GL V+ ++ Sbjct: 1591 NPYFNFITAFTVPDIDDVTVIDFDASEERLYW--TDIKTQTIKRAFINGTGLETVISRDI 1648 Query: 467 IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMR 526 + +AVDW+ N+++ S I++ + G +I G ++ Q L HP+R Sbjct: 1649 QSIRGLAVDWVSRNLYWIS-SEFDETQINVARLDGSLKTSIIHGIDKPQC---LAAHPVR 1704 Query: 527 GLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIER 586 G + W D + I MANMDGS +IL N+ E P L+IDY+ + +Y+ I R Sbjct: 1705 GKLYWTDG----NTINMANMDGSNSKILFQNQKE-PVGLSIDYVENKLYWISSGNGTINR 1759 Query: 587 VNIDTKERRVV--ISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFN 644 N+D V+ + + + + L+WAD L +P ++ Sbjct: 1760 CNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCS-KRDGRNPTILRNKT 1818 Query: 645 RYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENSC 704 + V Q G S C LC +P S+ T C+C GY SC Sbjct: 1819 SGVVHMKVYDKEAQQGSNSCQLNNGGCSQLC--LPTSE--TTRTCMCTVGYYLQKNRMSC 1874
Score = 66.2 bits (160), Expect = 2e-09 Identities = 74/295 (25%), Positives = 132/295 (44%), Gaps = 25/295 (8%) Query: 343 CATHGHLCQHFCEDRLGS-FACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 CA C+ C R S C CA+GY L DG +C EGYL S ++ + Sbjct: 2147 CARDNGGCKQLCLYRGNSRRTCACAHGY-LAEDGVTCLRH-----EGYLLYSGRTILKSI 2200 Query: 402 PLADFTDGSNYSAIQKFAGHGTIRSI-----DFMHR---NNKMFMSISDEHGDPTGELS- 452 L+D T+ + S I+ + +++ D+ R N++F SD H G + Sbjct: 2201 HLSDETNLN--SPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFY--SDAH---FGNIQL 2253 Query: 453 VSDNGLMR-VLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISI-CTMSGMFCRRVIEG 510 + DN R V+ ENV V +A +++T + S ++ T G F R + Sbjct: 2254 IKDNWEDRQVIVENVGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQTRPGAFDREAVIT 2313 Query: 511 KEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYI 570 + L + + L+ W + +++ IM + + G ++++ + P+ L IDY Sbjct: 2314 MSEDDHPHVLALDECQNLMFWTNWNEQHPSIMRSTLTGKNAQVVVSTDILTPNGLTIDYR 2373 Query: 571 RHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL 625 +YF D IER D +R V++ +G +A ++ +++W+DWG ++ Sbjct: 2374 AEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDWGRRAI 2428
Score = 45.8 bits (107), Expect = 0.003 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%) Query: 519 GLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGD 578 G+ H I W D +++I A D + ++ N L +A+D+I ++Y+ D Sbjct: 1914 GIDFHAENDTIYWTD--MGFNKISRAKRDQTWKEDIITNGLGRVEGIAVDWIAGNIYWTD 1971 Query: 579 VERQLIERVNIDTKERRVVISNGVHHPYDMAYF--NGFLYWADWG 621 LIE ++ R V+IS G+ P +A G L+W +WG Sbjct: 1972 HGFNLIEVARLNGSFRYVIISQGLDQPRSIAVHPEKGLLFWTEWG 2016
>gi|21291650|gb|EAA03795.1| ebiP6309 [Anopheles gambiae str. PEST] Length = 749 Score = 195 bits (495), Expect = 3e-48 Identities = 185/688 (26%), Positives = 292/688 (42%), Gaps = 113/688 (16%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCV 88 N TC ++ EF CGNG RCI W CD+ DC DE C C C+ Sbjct: 140 NETC-RSDEFTCGNG--RCIQKRWVCDHDDDCGDKTDEDNCPTTTCDPLKQFACAENYCI 196 Query: 89 ANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG- 147 ++++CDGE DC DGSDE+ + KS TTF C P +C Sbjct: 197 TSKWRCDGEPDCPDGSDER---VRMCKS---------TTTF-----STCLPLEYQCNDRI 239 Query: 148 QCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSG 207 CI +CDG +DC GDDE+ P N CRS Sbjct: 240 TCIHRSWICDGEKDCPRGDDEM------------------------PPICQNV--TCRSD 273 Query: 208 YTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYS 267 C CI E+NC N SE+ C+ + Sbjct: 274 QFQCKKDKTCINGHFACNGKNDCSDGSDEQNCGVNVRSEK------------CNPKTEFD 321 Query: 268 CGTKGSEIGVCIPMNATCNGIKECP-LGDDESKHC--SECARKR--CDHTCMNTPHGARC 322 CG G+CIP+ C+ +CP D+ + C +EC + C C++TP G C Sbjct: 322 CGG-----GMCIPLAKVCDQNPDCPEFQDEPADKCGKNECLQGNGGCSQLCVDTPAGFYC 376 Query: 323 ICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHS-CKYE 381 C+ G+KLAD+ TC D DEC G C C + +G+F C+C + Y + H+ CK Sbjct: 377 DCKPGFKLADN-RTCVDIDECEEPGS-CSQSCINEIGTFKCECMDNYLRDPRDHTRCK-- 432 Query: 382 ATTTPEGY--LFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMS 439 EG+ L + ++R++ L D ++I T ++DF+ R ++ S Sbjct: 433 ---PKEGHASLLFARRHDIRKISL----DHREMTSIVNDTKSAT--ALDFVFRTGMIYWS 483 Query: 440 ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTM 499 E + + + V+++ ++ +AVDWI +++FT S I + Sbjct: 484 DVSEKRIYKAPIDEGSDKTV-VVKDQLVTSDGLAVDWIYNHIYFTDIKKST---IELTNF 539 Query: 500 SGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKL 559 G + +I+ + + R + + P+ G + W D + RI A MDG+ ++++ ++ Sbjct: 540 DGNMGKVLIQ--DDLEIPRAIALDPIDGWMYWTD-WGTNPRIERAGMDGTHRQVIVSYEV 596 Query: 560 EVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI--SNGVHHPYDMAYFNGFLYW 617 + P+ + +D +R VY+ D + +I N D +R V++ ++ + HP+ + F ++YW Sbjct: 597 KWPNGITLDLVRKRVYWVDAKLNVISSCNYDGSKRSVILYSADYLRHPFSITTFEDYVYW 656 Query: 618 ADWGSESL---------KVQEMTHHH--SSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPC 666 DW E++ V+ +T H P IH ++ Y VNH G S+ C Sbjct: 657 TDWDKEAVFKANKFTGKDVEPVTAMHMLQHPMTIHVYHPYRQPDGVNHCQAVNGHCSHLC 716 Query: 667 LELECPWLCVIVPKSDFIMTAKCVCPDG 694 L P + PK C CP G Sbjct: 717 --LPAPQINANSPK------ISCACPTG 736
Score = 50.4 bits (119), Expect = 1e-04 Identities = 62/232 (26%), Positives = 82/232 (35%), Gaps = 63/232 (27%) Query: 136 ECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT 195 +C + RC SGQCI VCDG DC+ G DE DVH+ T Sbjct: 18 QCAERQFRCGSGQCIHISFVCDGEDDCNDGSDE-------------------DVHVCKIT 58 Query: 196 FFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXE--KNCQTNAPSEEEYLSGQ 253 ++ C C +G CI E + CQ+ S EE+ Sbjct: 59 -----ESSCPGDKFRCKNGR-CILKRWQCDGERDCADGSDEDAQQCQSKVCSSEEF---- 108 Query: 254 ADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTC 313 T S G CIP+ C+ ++C G DE C+E R + TC Sbjct: 109 ----------------TCRSGTGNCIPLGWMCDQNRDCADGSDEMS-CNETCRSD-EFTC 150 Query: 314 MNTPHGARCICQEGYKLADDGLTCEDEDECA--THGHLCQHFCEDRLGSFAC 363 N RCI + C+ +D+C T C D L FAC Sbjct: 151 GN----GRCIQKR--------WVCDHDDDCGDKTDEDNCPTTTCDPLKQFAC 190
Score = 35.8 bits (81), Expect = 3.3 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 19/100 (19%) Query: 27 VNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDE--------------SGCSY- 71 V + C+ EFDCG G CIP CD DC + +DE GCS Sbjct: 309 VRSEKCNPKTEFDCGGG--MCIPLAKVCDQNPDCPEFQDEPADKCGKNECLQGNGGCSQL 366 Query: 72 -AHHCSTSFMLCKNGLCVANEFKCDGEDDCRD-GSDEQHC 109 + + CK G +A+ C D+C + GS Q C Sbjct: 367 CVDTPAGFYCDCKPGFKLADNRTCVDIDECEEPGSCSQSC 406
>gi|476532|pir||QRXLL2 LDL receptor 2 precursor - African clawed frog Length = 909 Score = 194 bits (493), Expect = 5e-48 Identities = 187/712 (26%), Positives = 304/712 (42%), Gaps = 92/712 (12%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC A +F CG RCIP W+CD DC+ G DE+ C+ C+ C++G C++ Sbjct: 67 TCG-ADQFSCGGRLNRCIPLFWKCDGQTDCENGSDENDCT-RKVCADDQFTCRSGKCISL 124 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQC 149 +F CD + DC DGSDE +C P C+P +C+ G C Sbjct: 125 DFVCDEDQDCDDGSDESYCP-----------------------APTCNPAMFQCKDKGIC 161 Query: 150 IQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSST-----DFH----DDVHLVDPTFFANE 200 I CDG +DC G DE +C G E +++ +FH + +H+ Sbjct: 162 IPKLWACDGDRDCEDGSDEEHC--EGREPIKTDKPCAPLEFHCGSGECIHM--------- 210 Query: 201 DNKCRSGYTMCHSGDV--CIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQAD--H 256 KC GY D C+ + Q + + + LS + + Sbjct: 211 SWKCDGGYDCKDKSDEKDCVKPTCRPDQFQCNDGTCIHGSRQCDREYDCKDLSDEEGCVN 270 Query: 257 MHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHC--SECARKR--CDH 311 + C ++ C + G CI M+ C+ ++C DE K C +EC R C H Sbjct: 271 VTKCEGPDVFKCRS-----GECITMDKVCDKKRDCRDWTDEPIKECGENECLRNNGGCSH 325 Query: 312 TCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYEL 371 C + G C+C EGY+L D CED +EC + + C C + G + C+C GY++ Sbjct: 326 ICNDLKIGYECLCNEGYRLVDQK-RCEDINEC-ENPNTCSQICINLDGGYKCECREGYQM 383 Query: 372 ETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMH 431 + SCK T YLF + EVR+M L D S Y++ + ++D Sbjct: 384 DPVTASCKSIGTV---AYLFFTNRHEVRKMTL----DRSEYTSF--IPRLKNVVALDMEI 434 Query: 432 RNNKMFMSISDEHGDPTGELSVSDNGLMR--VLRENVIGVSNVAVDWIGGNVFFTQKSPS 489 +NK++ S + + + +DN V+ + +AVDWI GN+++T S Sbjct: 435 ASNKIYWSDLTQRKIYSASMDKADNTSHHETVISNQIQAPDGIAVDWIHGNIYWTD---S 491 Query: 490 PSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGS 549 + IS+ G +R + R +VV P +G + W D + +I ++G Sbjct: 492 KFSTISVANTEG--SKRKTLFTDDLAKPRDIVVDPSQGFMYWTD-WGLPAKIEKGGLNGV 548 Query: 550 QVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH--HPYD 607 L+ + +E P+ + +D I +Y+ D + + ++I + RR V+S+ H HP+ Sbjct: 549 DRYPLVTDNIEWPNGITLDLISQRLYWVDSKLHSLSCIDITGENRRTVLSDETHLAHPFG 608 Query: 608 MAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCL 667 + F ++W D +E++ + + +V P I + H+L Q P + Sbjct: 609 LTIFEDLVFWTDIENEAIFSAKRLTGENIMKVAEDL-LSPEDIVLYHNLRQ--PKAENWC 665 Query: 668 ELE------CPWLCVIVPKSDFIMTA-KCVCPDGYTHSVTENSCIP-PVTIE 711 E C +LC+ P + C CPDG +C+ PVT E Sbjct: 666 ESHHLGNGGCGYLCLPAPHVNARSPKFTCACPDGMHLGTDMRNCMKEPVTQE 717
>gi|16506799|gb|AAL23955.1|AF425607_1 low density lipoprotein receptor [Mus musculus] Length = 862 Score = 193 bits (491), Expect = 8e-48 Identities = 176/713 (24%), Positives = 294/713 (41%), Gaps = 81/713 (11%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 ++P S Q+ +F CG RCIP W+CD DC+ DE GC CS C Sbjct: 58 ESPETCMSVTCQSNQFSCGGRVSRCIPDSWRCDGQVDCENDSDEQGCP-PKTCSQDDFRC 116 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL 142 ++G C++ +F CDG+ DC DGSDE HC+ C P Sbjct: 117 QDGKCISPQFVCDGDRDCLDGSDEAHCQ-----------------------ATTCGPAHF 153 Query: 143 RCRSGQCIQPDLVCDGHQDCSGGDDE--VNCTRR-----GHENMQSSTDFH-DDVHLVDP 194 RC S CI CDG DC G DE NC R G + SS +FH + Sbjct: 154 RCNSSICIPSLWACDGDVDCVDGSDEWPQNCQGRDTASKGVSSPCSSLEFHCGSSECIHR 213 Query: 195 TFFANEDNKCRSGYTMCHSG-DVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQ 253 ++ + + C+ H C P + C ++ Sbjct: 214 SWVCDGEADCKDKSDEEHCAVATCRP---DEFQCADGSCIHGSRQCDREHDCKDMSDELG 270 Query: 254 ADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHC--SECARKR-- 308 ++ C + C + G CI ++ C+ ++C DE K C +EC Sbjct: 271 CVNVTQCDGPNKFKCHS-----GECISLDKVCDSARDCQDWSDEPIKECKTNECLDNNGG 325 Query: 309 CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANG 368 C H C + G+ C+C G++L D CED DEC C C + GS+ C+C G Sbjct: 326 CSHICKDLKIGSECLCPSGFRLVDLH-RCEDIDEC-QEPDTCSQLCVNLEGSYKCECQAG 383 Query: 369 YELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSID 428 + ++ CK + GYL + EVR+M L D S Y+++ + ++D Sbjct: 384 FHMDPHTRVCKAVGSI---GYLLFTNRHEVRKMTL----DRSEYTSL--LPNLKNVVALD 434 Query: 429 FMHRNNKMFMSISDEHGDPTGELSVSDN-GLMRVLRENVIGVSNVAVDWIGGNVFFTQKS 487 NN+++ S + + + + N ++ E++ +AVDWI N+++T Sbjct: 435 TEVTNNRIYWSDLSQKKIYSALMDQAPNLSYDTIISEDLHAPDGLAVDWIHRNIYWTDSV 494 Query: 488 PSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMD 547 P +S+ G+ R + + E G R +VV P+ G + W D + +I ++ Sbjct: 495 P---GSVSVADTKGVKRRTLFQ--EAGSRPRAIVVDPVHGFMYWTD-WGTPAKIKKGGLN 548 Query: 548 GSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI--SNGVHHP 605 G + L+ ++ P+ + +D +Y+ D + I ++++ R+ ++ N + HP Sbjct: 549 GVDIHSLVTENIQWPNGITLDLSSGRLYWVDSKLHSISSIDVNGGNRKTILEDENRLAHP 608 Query: 606 YDMAYFNGFLYWADWGSESL---------KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSL 656 + +A + +YW D +E++ V + + SP+ I F++ VN Sbjct: 609 FSLAIYEDKVYWTDVINEAIFSANRLTGSDVNLVAENLLSPEDIVLFHKVTQPRGVNWCE 668 Query: 657 YQTGPPSNPCLELECPWLCVIVPK-SDFIMTAKCVCPDGYTHSVTENSCIPPV 708 P++ C +LC+ P+ C CPDG + SC+ V Sbjct: 669 TTALLPNS-----GCQYLCLPAPQIGPHSPKFTCACPDGMLLAEDMRSCLTEV 716
>gi|17512511|gb|AAH19207.1| Similar to low density lipoprotein receptor [Mus musculus] Length = 862 Score = 193 bits (491), Expect = 9e-48 Identities = 176/713 (24%), Positives = 293/713 (41%), Gaps = 81/713 (11%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 ++P S Q+ +F CG RCIP W+CD DC+ DE GC CS C Sbjct: 58 ESPETCMSVTCQSNQFSCGGRVSRCIPDSWRCDGQVDCENDSDEQGCP-PKTCSQDDFRC 116 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL 142 ++G C++ +F CDG+ DC DGSDE HC+ C P Sbjct: 117 QDGKCISPQFVCDGDRDCLDGSDEAHCQ-----------------------ATTCGPAHF 153 Query: 143 RCRSGQCIQPDLVCDGHQDCSGGDDE--VNCTRR-----GHENMQSSTDFH-DDVHLVDP 194 RC S CI CDG DC G DE NC R G + SS +FH + Sbjct: 154 RCNSSICIPSLWACDGDVDCVDGSDEWPQNCQGRDTASKGVSSPCSSLEFHCGSSECIHR 213 Query: 195 TFFANEDNKCRSGYTMCHSG-DVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQ 253 ++ + + C+ H C P + C ++ Sbjct: 214 SWVCDGEADCKDKSDEEHCAVATCRP---DEFQCADGSCIHGSRQCDREHDCKDMSDELG 270 Query: 254 ADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHC--SECARKR-- 308 ++ C + C + G CI ++ C+ ++C DE K C +EC Sbjct: 271 CVNVTQCDGPNKFKCHS-----GECISLDKVCDSARDCQDWSDEPIKECKTNECLDNNGG 325 Query: 309 CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANG 368 C H C + G+ C+C G++L D CED DEC C C + GS+ C+C G Sbjct: 326 CSHICKDLKIGSECLCPSGFRLVDLH-RCEDIDEC-QEPDTCSQLCVNLEGSYKCECQAG 383 Query: 369 YELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSID 428 + ++ CK + GYL + EVR+M L D S Y+++ + ++D Sbjct: 384 FHMDPHTRVCKAVGSI---GYLLFTNRHEVRKMTL----DRSEYTSL--LPNLKNVVALD 434 Query: 429 FMHRNNKMFMSISDEHGDPTGELSVSDN-GLMRVLRENVIGVSNVAVDWIGGNVFFTQKS 487 NN+++ S + + + + N ++ E++ +AVDWI N+++T Sbjct: 435 TEVTNNRIYWSDLSQKKIYSALMDQAPNLSYDTIISEDLHAPDGLAVDWIHRNIYWTDSV 494 Query: 488 PSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMD 547 P +S+ G+ R + + E G R +VV P+ G + W D + +I ++ Sbjct: 495 P---GSVSVADTKGVKRRTLFQ--EAGSRPRAIVVDPVHGFMYWTD-WGTPAKIKKGGLN 548 Query: 548 GSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI--SNGVHHP 605 G + L+ ++ P+ + +D +Y+ D + I ++++ R+ ++ N + HP Sbjct: 549 GVDIHSLVTENIQWPNGITLDLSSGRLYWVDSKLHSISSIDVNGGNRKTILEDENRLAHP 608 Query: 606 YDMAYFNGFLYWADWGSESL---------KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSL 656 + +A + +YW D +E++ V + + SP+ I F++ VN Sbjct: 609 FSLAIYEDKVYWTDVINEAIFSANRLTGSDVNLVAENLLSPEDIVLFHKVTQPRGVNWCE 668 Query: 657 YQTGPPSNPCLELECPWLCVIVPK-SDFIMTAKCVCPDGYTHSVTENSCIPPV 708 P+ C +LC+ P+ C CPDG + SC+ V Sbjct: 669 TTALLPNG-----GCQYLCLPAPQIGPHSPKFTCACPDGMLLAKDMRSCLTEV 716
>gi|2118672|pir||I48623 low density lipoprotein receptor - mouse gi|7428600|pir||QRMSLD LDL receptor precursor - mouse gi|296202|emb|CAA45759.1| low density lipoprotein receptor [Mus musculus] Length = 862 Score = 193 bits (491), Expect = 1e-47 Identities = 176/713 (24%), Positives = 293/713 (41%), Gaps = 81/713 (11%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 ++P S Q+ +F CG RCIP W+CD DC+ DE GC CS C Sbjct: 58 ESPETCMSVTCQSNQFSCGGRVSRCIPDSWRCDGQVDCENDSDEQGCP-PKTCSQDDFRC 116 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRL 142 ++G C++ +F CDG+ DC DGSDE HC+ C P Sbjct: 117 QDGKCISPQFVCDGDRDCLDGSDEAHCQ-----------------------ATTCGPAHF 153 Query: 143 RCRSGQCIQPDLVCDGHQDCSGGDDE--VNCTRR-----GHENMQSSTDFH-DDVHLVDP 194 RC S CI CDG DC G DE NC R G + SS +FH + Sbjct: 154 RCNSSICIPSLWACDGDVDCVDGSDEWPQNCQGRDTASKGVSSPCSSLEFHCGSSECIHR 213 Query: 195 TFFANEDNKCRSGYTMCHSG-DVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQ 253 ++ + + C+ H C P + C ++ Sbjct: 214 SWVCDGEADCKDKSDEEHCAVATCRP---DEFQCADGSCIHGSRQCDREHDCKDMSDELG 270 Query: 254 ADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHC--SECARKR-- 308 ++ C + C + G CI ++ C+ ++C DE K C +EC Sbjct: 271 CVNVTQCDGPNKFKCHS-----GECISLDKVCDSARDCQDWSDEPIKECKTNECLDNNGG 325 Query: 309 CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANG 368 C H C + G+ C+C G++L D CED DEC C C + GS+ C+C G Sbjct: 326 CSHICKDLKIGSECLCPSGFRLVDLH-RCEDIDEC-QEPDTCSQLCVNLEGSYKCECQAG 383 Query: 369 YELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSID 428 + ++ CK + GYL + EVR+M L D S Y+++ + ++D Sbjct: 384 FHMDPHTRVCKAVGSI---GYLLFTNRHEVRKMTL----DRSEYTSL--LPNLKNVVALD 434 Query: 429 FMHRNNKMFMSISDEHGDPTGELSVSDN-GLMRVLRENVIGVSNVAVDWIGGNVFFTQKS 487 NN+++ S + + + + N ++ E++ +AVDWI N+++T Sbjct: 435 TEVTNNRIYWSDLSQKKIYSALMDQAPNLSYDTIISEDLHAPDGLAVDWIHRNIYWTDSV 494 Query: 488 PSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMD 547 P +S+ G+ R + + E G R +VV P+ G + W D + +I ++ Sbjct: 495 P---GSVSVADTKGVKRRTLFQ--EAGSRPRAIVVDPVHGFMYWTD-WGTPAKIKKGGLN 548 Query: 548 GSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVI--SNGVHHP 605 G + L+ ++ P+ + +D +Y+ D + I ++++ R+ ++ N + HP Sbjct: 549 GVDIHSLVTENIQWPNGITLDLSSGRLYWVDSKLHSISSIDVNGGNRKTILEDENRLAHP 608 Query: 606 YDMAYFNGFLYWADWGSESL---------KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSL 656 + +A + +YW D +E++ V + + SP+ I F++ VN Sbjct: 609 FSLAIYEDKVYWTDVINEAIFSANRLTGSDVNLVAENLLSPEDIVLFHKVTQPRGVNWCE 668 Query: 657 YQTGPPSNPCLELECPWLCVIVPK-SDFIMTAKCVCPDGYTHSVTENSCIPPV 708 P+ C +LC+ P+ C CPDG + SC+ V Sbjct: 669 TTALLPNG-----GCQYLCLPAPQIGPHSPKFTCACPDGMLLAKDMRSCLTEV 716
>gi|25012574|gb|AAN71387.1| RE38584p [Drosophila melanogaster] Length = 739 Score = 193 bits (490), Expect = 1e-47 Identities = 191/704 (27%), Positives = 299/704 (42%), Gaps = 120/704 (17%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCV 88 N TC +A EF CGNG RCI W+CD+ DC G DE C S + C NG C+ Sbjct: 18 NQTC-RADEFTCGNG--RCIQKRWKCDHDDDCGDGSDEKECPVVPCDSVAEHTCTNGACI 74 Query: 89 ANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG- 147 A + CDG+ DC DGSDE+ C +N + TT C +C+ Sbjct: 75 AKRWVCDGDPDCSDGSDERSC-----------ANVTKTTT-------PCLSHEYQCKDRI 116 Query: 148 QCIQPDLVCDGHQDCSGGDDE--VNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCR 205 C+ +CDG +DC GDDE NC +N+ D F D C Sbjct: 117 TCLHHSWLCDGDRDCPDGDDEHTANC-----KNVTCRAD-----------QFQCGDRSCI 160 Query: 206 SGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLS-GQADHMHSCSAAG 264 G+ C+ +K+C + + LS + C+A Sbjct: 161 PGHLTCNG----------------------DKDCADGSDERDCGLSLSLGINQGGCNATS 198 Query: 265 MYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE-SKHC--SECARKR--CDHTCMNTPHG 319 + CG G C+P++ C+ K+CP G+DE + C +ECA K C H C++ G Sbjct: 199 EFDCGG-----GQCVPLSKVCDKRKDCPDGEDEPAGKCGINECASKNGGCMHQCIDLKVG 253 Query: 320 ARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHS-C 378 C C EGYKL+ D C+D +EC G C C + +G F C+C GY + H+ C Sbjct: 254 HHCECHEGYKLSPDKRNCQDINECEVPGK-CSQICVNEIGGFKCECEAGYMRDPKNHTRC 312 Query: 379 KYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFM 438 K + L ++ ++R++ L D ++I T ++DF+ R +F Sbjct: 313 K---ASEGHASLLLARRHDIRKIAL----DHMEMTSIVNSTKAAT--ALDFVFRTGMIFW 363 Query: 439 S---ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGIS 495 S + P E N VL ++ + +AVDWI +V+FT + I Sbjct: 364 SDVTTQSIYKAPIDE----GNEKTVVLTKSSVTSDGLAVDWIYNHVYFTD---THKCTIE 416 Query: 496 ICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILL 555 + G + ++ K+ R + + P+ G + W D + RI A MDGS ++ Sbjct: 417 LTNFEGSMGKVLV--KDSLDIPRSIALDPIEGWMYWSD-WGASPRIERAGMDGSHRTTII 473 Query: 556 DNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNG 613 ++ P+ + +D ++ +Y+ D + +I N D +R V+ +G + HP+ + F Sbjct: 474 SYDVKWPNGITLDLVKKRIYWVDGKLNVISSANYDGSQRSQVLYSGEYLRHPFSITTFED 533 Query: 614 FLYWADWGSESL---------KVQEMTHHH--SSPQVIHTFNRYPYGIAVNHSLYQTGPP 662 +YW DW +++ V+ +T H P V+H ++ Y VNH G Sbjct: 534 NVYWTDWDKQAVFKANKFTGEDVEPVTAMHMLQHPMVVHVYHPYRQPDGVNHCQSVNG-- 591 Query: 663 SNPCLELECPWLCVIVPK-SDFIMTAKCVCPDGYTHSVTENSCI 705 C LC+ P+ ++ C CP G V C+ Sbjct: 592 -------HCSHLCLPAPRINERSPRISCACPTGLKLMVDGLMCV 628
Score = 42.7 bits (99), Expect = 0.028 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 12/90 (13%) Query: 27 VNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGL 86 +N C+ EFDCG G +C+P CD DC G DE A C + KNG Sbjct: 189 INQGGCNATSEFDCGGG--QCVPLSKVCDKRKDCPDGEDEP----AGKCGINECASKNGG 242 Query: 87 CVAN--EFKCDGEDDCRDG----SDEQHCE 110 C+ + K +C +G D+++C+ Sbjct: 243 CMHQCIDLKVGHHCECHEGYKLSPDKRNCQ 272
>gi|24586537|ref|NP_610365.1| CG8706-PA [Drosophila melanogaster] gi|23240381|gb|AAF59114.3| CG8706-PA [Drosophila melanogaster] Length = 4699 Score = 192 bits (489), Expect = 2e-47 Identities = 182/692 (26%), Positives = 288/692 (41%), Gaps = 93/692 (13%) Query: 27 VNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCK-NG 85 +N T + +F C CIPA WQCD +DC+ G DE C CK +G Sbjct: 2789 INCRTECRHNQFACDK---TCIPASWQCDGKSDCEDGSDEGPQCPNRPCRPHLFQCKSSG 2845 Query: 86 LCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR 145 C+ ++ CDGE DC G ++ GS P + P+C PP C Sbjct: 2846 RCIPQKWVCDGEKDCPSGLGDE------------GSEDEGPQCGGVAHIPDCPPPAHLCT 2893 Query: 146 SGQCIQPDLVCDGHQDCSGGDDEVN-CTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKC 204 SG CI VCDG +DC GGDDE C P F + + C Sbjct: 2894 SGLCIDSHYVCDGDEDCPGGDDEYEGCV---------------------PAF---QPHSC 2929 Query: 205 RSGYTM--CHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSA 262 G M C G +CI + +C + + S H C+ Sbjct: 2930 PGGSLMHQCQDG-LCI---------FKNQTCDGKPDCGDGS----DETSSLCAHTRGCNG 2975 Query: 263 AGMYSCGTKGSEIGVCIPMNATCNGIKECP-LGDDESKHCSECARKR-CDHTCMNTPHGA 320 + C G CI + C+ +C D+E + +EC C+H C + G Sbjct: 2976 TDDFRCKN-----GACIHADLLCDRRNDCADFSDEELCNVNECLIPDICEHECEDKVVGY 3030 Query: 321 RCICQEGYK-LADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCK 379 +C C+ GYK L C D DEC C C + GS+ C CA GY L D H+CK Sbjct: 3031 QCHCRPGYKVLPKSPHLCTDIDECDEQ-QPCSQTCINTYGSYKCLCAKGYAL-VDHHTCK 3088 Query: 380 YEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMS 439 AT+ L S +RQ+ + G+ I + + ++D+ + ++ S Sbjct: 3089 --ATSNVSMELIFSNRYYIRQVDMT----GNGSILINELS---NAVALDYDWDSQCLYWS 3139 Query: 440 ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTM 499 +N + + + +AVDW+ N+++ K I + + Sbjct: 3140 DVTSTVGTIKRYCPKENKTQTLHQAMLKNPDGLAVDWVAKNLYWCDKGLDT---IEVSQL 3196 Query: 500 SGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKL 559 G + + +I E + RG+ +HP + I W D H I A MDGS ++++ + L Sbjct: 3197 DGKYRKVLI--NEYLREPRGIALHPYQQHIFWSDWGDSPH-IGKAGMDGSNPKMIIRDGL 3253 Query: 560 EVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGV------HHPYDMAYFNG 613 P+AL I + +++GD I ++D R++++ + HH + +A + G Sbjct: 3254 GWPNALTISFETQQLFWGDAREDTISVSDLDGNHTRLLLARSINPLLNLHHIFAIAVWEG 3313 Query: 614 FLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPS-NPCLELECP 672 +YW+DW ++S++ + + + +I T +R P + V H Q P S NPCL C Sbjct: 3314 HIYWSDWETKSIEYCSIFNGQNCTTLITTIHR-PMDLRVFHPYRQQQPMSGNPCLAANCS 3372 Query: 673 WLCVIVPKSDFIMTAKCVCPDGYTHSVTENSC 704 LCV+ P+ + KC+CP + + +C Sbjct: 3373 TLCVLSPEEPYY---KCMCPTNFILADDGRTC 3401
Score = 174 bits (441), Expect = 5e-42 Identities = 184/704 (26%), Positives = 279/704 (39%), Gaps = 104/704 (14%) Query: 28 NNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADC---DKGRDESGCSYAHHCSTSFMLCKN 84 + +TC+ + EF C RCI W D V DC D + S +A C C N Sbjct: 1006 HQNTCN-SNEFTCHKSG-RCIQLTWVNDGVVDCGPDDDSDETSETIFASKCPE--FDCNN 1061 Query: 85 GLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRC 144 G C CDG D+C + +DE CE EC C Sbjct: 1062 GRCRQFADVCDGIDNCGNNADEMECE------------------------QECEHGEKYC 1097 Query: 145 RSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKC 204 R C +CDG DC DE NC Q+ +D H P E +C Sbjct: 1098 RPIGCYGEMHMCDGIHDCLDFSDEANCN-------QTKSDNH-------PVTEWKELGEC 1143 Query: 205 RSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC----QTNAPSEEEYLSGQADHMHSC 260 C CIP E NC T E + D + Sbjct: 1144 APLEFACMFPFECIPDFLRCDGISHCFDKTDEFNCTHINTTRFDMNETVICEHPDRL--- 1200 Query: 261 SAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSE--CAR-KRCDHTCMNTP 317 CG C+ ++ C+G +C DE C++ C R C H C NTP Sbjct: 1201 -------CGFSKQ----CVTVDQLCDGKNDCEDTTDEGFLCADKLCDRGHECSHRCHNTP 1249 Query: 318 HGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHS 377 G C C + L +G C + C H C CE + C+C +G++L D + Sbjct: 1250 EGYICSCPDHLYLQPNGKRCSMQHAC-DHWDTCSQVCESSGKGYDCRCLDGFDLGFDRFT 1308 Query: 378 CKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNK-- 435 CK +T E Y+ + +++ + L G+ YS+++ I ++DF++ N Sbjct: 1309 CK--STAPDEPYVIFTNRQDIKGINLKTLNVGNFYSSLR------NIIALDFLYNNESNV 1360 Query: 436 --MFMSISDE---HGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSP 490 + + D+ G GE S + V+ + +AVDW+G N+++ + Sbjct: 1361 EIYWTDVIDDKIYRGHLVGE---SLRNVEAVIHSGLSTTEGLAVDWVGKNLYWIDSNLDQ 1417 Query: 491 SAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQ 550 I + ++G F R +I G +S R + + P GL+ W D RI A+M G Sbjct: 1418 ---IEVAKLNGSFRRTLIAGNM--ESPRAIALDPREGLLFWTDWDDNSPRIERASMSGDG 1472 Query: 551 VRILLDN-KLEV--PSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHP 605 R++ + +L P+ L +DY + VY+ D + I D E VV+ N + HP Sbjct: 1473 RRMISTSWQLSAGWPNGLTLDYTQKRVYWVDAKSDSISSTMYDGSEHHVVLRNKEILSHP 1532 Query: 606 YDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNP 665 + ++ F ++YW DW + S+ ++ + S QV+ P+GI V HS Q NP Sbjct: 1533 FAISVFENYVYWTDWRTTSV-IRANKWNGSDVQVLQRTQSQPFGIQVLHSSRQPW-DRNP 1590 Query: 666 CLELE--CPWLCVIVPKSDFIMTAKCVCPDGYT-HSVTENSCIP 706 C E C LC++ + F KC CP E +C+P Sbjct: 1591 CGENNGGCSHLCLLSGRGTF----KCECPHVMRLDPANERNCVP 1630
Score = 98.2 bits (243), Expect = 5e-19 Identities = 178/812 (21%), Positives = 282/812 (34%), Gaps = 172/812 (21%) Query: 35 AKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKC 94 A F+C N +CIP W+CD DC G DE HC C N C C Sbjct: 3407 AAHFECVN-TYKCIPFYWRCDTQDDCGDGSDEPETCPPFHCEPGQYQCANKKCTHPSNLC 3465 Query: 95 DGEDDCRDGSDEQHCE-YNILKSRFDGSNPSAPTTFV---------------GHNGPECH 138 DG + C DGSDE +C+ + + + + F G + C Sbjct: 3466 DGINQCGDGSDELNCDKFTCFDNHMKCGATANSSAFCVDNVKRCDGVKDCPGGEDESACT 3525 Query: 139 P-----PRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRR--GHENMQSST-------- 183 P + +C + +C+ VCDG DC DE NC G + Q + Sbjct: 3526 PLVCKKDQFQCGNNRCMPFVWVCDGDIDCPDKSDEANCDNVSCGPNDFQCDSGRCIPLAW 3585 Query: 184 ---DFHDDVHLVD-PTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNC 239 D HD + D P + C Y C++ CIP E NC Sbjct: 3586 RCDDDHDCPNGEDEPASCFSSKATCDPTYFKCNNSK-CIPGRWRCDYENDCGDGSDELNC 3644 Query: 240 QTNAPSEEEYLSGQADHM-HSCSAAGMYSCGTKGSEI----------------------- 275 Q SE E+ G + H+ G C EI Sbjct: 3645 QMRNCSESEFRCGTGKCIKHNYRCDGEIHCDDNSDEINCNITCKENQFKCAAFNTCINKQ 3704 Query: 276 -----------------------------GVCIPMNATCNGIKECPLGDDES------KH 300 G CI C+G +C G DES H Sbjct: 3705 YKCDGDDDCPDGSDEVNCTCHSDHFSCGNGKCIMSRWKCDGWDDCLDGSDESLETCAKTH 3764 Query: 301 CSE---------CARKR--CD--HTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHG 347 C C R CD + C + +C K D CE+ D+C + Sbjct: 3765 CHANAFKCRNQLCVRNSALCDGINDCGENEDESDAVCAALPKCRHDQFQCEN-DDCISKA 3823 Query: 348 HLC--QHFC------------------------EDRLGSFACKCANGYELETDGHSCKYE 381 C Q+ C E + G + CKCA+GY + ++ Sbjct: 3824 FRCDGQYNCVDGSDEMNCQPPVCGFGSCSQICIEKKAGHYNCKCADGYHKGPEKNATCL- 3882 Query: 382 ATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMF---- 437 + P+ L ++ E R + A + Q + + I ++ +F Sbjct: 3883 -ASGPDQILLLASEQEFRFILPAKQEGTTVVGFFQTDSLKIDVFDILIRPKDTLLFWIDS 3941 Query: 438 -------MSISDEHGDPTGELSVSDNGLMRVLRENVIGVSN---VAVDWIGGNVFFTQKS 487 M I+ H + TG D L + N+ + + +AVDWI V+ Sbjct: 3942 HHGKVHTMKIATPHVEGTGVRVRRD--LKELTAFNIPELDDPKSLAVDWISQRVYIID-- 3997 Query: 488 PSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMD 547 S I + G ++ I G + +V+ P ++IW + I++A++D Sbjct: 3998 -SRHNQILATDIEG---KKYISLVSTGMNPTDIVLEPESRIMIW---STLENGILVASLD 4050 Query: 548 GSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHH-PY 606 GS + L++ + P +L++DY +Y+ D + IE ++ K+R VV G P Sbjct: 4051 GSNKKSLVERDVGWPISLSMDYPTGRLYWADYRKGTIETCRLNGKDRNVVRRFGNREKPQ 4110 Query: 607 DMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPC 666 + F +LY + +K+ + + + + ++ + GI H + Q SNPC Sbjct: 4111 KIDVFEDYLYIKLYDQSIIKMNKFGNDNGT-YLLKGYRSSDIGIL--HPMKQNRNISNPC 4167 Query: 667 LELECP---WLCVIVPKSDFIMTAKCVCPDGY 695 + C LC++ +S + C C +GY Sbjct: 4168 AKDPCKSSRALCILSSESS--VGYSCKCAEGY 4197
Score = 92.8 bits (229), Expect = 2e-17 Identities = 92/331 (27%), Positives = 129/331 (38%), Gaps = 70/331 (21%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDE--SGCSYAHHCSTSFMLCKNGL 86 N++C + +++C +G CIP E CDNV C G DE S C + C + +C+N Sbjct: 2574 NTSCGLS-QYNCHSG--ECIPLELTCDNVTHCADGSDEFRSYCIF-RQCPETHFMCQNHR 2629 Query: 87 CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRS 146 C+ E KCDGE C DGSDE D +PS +N + P RC S Sbjct: 2630 CIPKEHKCDGEQQCGDGSDETPLLCKCQSEDID-MHPS-------NNNTKEMPDMFRCGS 2681 Query: 147 GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRS 206 G+CI +CD +DC DE C E D TF Sbjct: 2682 GECIPRKFLCDSLKDCRDFSDEKMCAPIPCEKN-------------DMTF---------- 2718 Query: 207 GYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMY 266 C + +CI E +C A+H G + Sbjct: 2719 --VHCGNSTICIMPRWRCDGDPDCPDGTDELDC--------------ANHTSLSCDPGQF 2762 Query: 267 SCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKR--CDHTCMNTPHGARC-- 322 C + G CI + C+G K+CP G DE +EC + CD TC+ P +C Sbjct: 2763 RCAS-----GNCIAGSWHCDGEKDCPDGSDEINCRTECRHNQFACDKTCI--PASWQCDG 2815 Query: 323 --ICQEGYKLADDGLTCEDEDECATHGHLCQ 351 C++G +D+G C + C H C+ Sbjct: 2816 KSDCEDG---SDEGPQCPNR-PCRPHLFQCK 2842
Score = 74.7 bits (182), Expect = 7e-12 Identities = 66/285 (23%), Positives = 124/285 (43%), Gaps = 17/285 (5%) Query: 343 CATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMP 402 CA C+ C S C CA+ L +DG+SC+ E +L S + + Sbjct: 2216 CAHSNGACEQLCLFNGTSAVCACAHS-RLASDGYSCE-----PYENFLLFSYRSNIESIH 2269 Query: 403 LADFTDGSNYSAIQKFAGHGTIRSIDFMHRN-NKMFMSISDEHGDPTGELSVSDNGLMRV 461 + D D N+ +Q + +R++ + N + + SD ++ + G RV Sbjct: 2270 MTDHAD-KNWP-VQMISNTSLMRNVIAITYNYEEQLVYYSDVQLSTINQVHFNGTG-HRV 2326 Query: 462 LRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMS------GMFCRRVIEGKEQGQ 515 L E V +A D + +F+T + + + + +S + ++V+ +E + Sbjct: 2327 LLEQQQRVEGLAYDIVNEQLFWTSNNNATIRSVELRHLSEHADQNQVHVKKVLSLREDDK 2386 Query: 516 SYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVY 575 RG+ V P G+I W + + I + + G +++ +++P+AL +D + +Y Sbjct: 2387 P-RGIAVEPCLGMIYWTNWNEGSPCIQRSYLTGYGTEVIIKTDIKMPNALTLDLEQQKLY 2445 Query: 576 FGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADW 620 + D IER N D R V+ + H + MA + L+W DW Sbjct: 2446 WADARLDKIERTNYDGSNRVVLAHSTPKHAFAMAVYGDLLFWTDW 2490
Score = 72.8 bits (177), Expect = 2e-11 Identities = 75/303 (24%), Positives = 126/303 (41%), Gaps = 38/303 (12%) Query: 426 SIDFMHRNNKMFMSISDEHGDP--TGELSVS------DNGLMRVLRENVIGVSNVAVDWI 477 +ID R +F ++D P GE S S + + R+L + + V VA DWI Sbjct: 630 AIDVNVRGKAVFYVVADSGASPFGNGEPSCSIRSQSLNGSVSRLLAQGLKRVHAVAFDWI 689 Query: 478 GGNVFFTQKSP---SPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWI-- 532 ++++T +P +S C + L + P GL+ W Sbjct: 690 NDHLYWTSHKKMQVAPLRNLSKVLTFNTDCDAM-----------SLELDPTTGLLYWSQW 738 Query: 533 DSYQKYHRIMMANMDGSQVRILLDNK----LEVPSALAIDYIRHDVYFGDVERQLIERVN 588 +S I + MDG+ +L ++ P +L +D ++Y+ D+ IE + Sbjct: 739 ESQSCEAGIYSSWMDGTHKELLAKGTSSMPMQWPRSLDVDRRTKELYWCDIRLSTIELMR 798 Query: 589 IDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPY 648 +D R V+ + HPY + NG +YWAD + ++ + S T + Sbjct: 799 LDGTGREVLFKSDQFHPYSIVQNNGLIYWADNKNSTILRFHAHQANLSSTFSSTVHLQRT 858 Query: 649 GIAVNHSLYQTGP---PSNP--CLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTENS 703 G A + ++ P P C + +CP +C+ PK A C CPDG+T + T + Sbjct: 859 GRAADLRIFDIASQPLPQTPSACAQSKCPGMCLNTPKG-----AICRCPDGFTLNGTGSH 913 Query: 704 CIP 706 CIP Sbjct: 914 CIP 916
Score = 71.2 bits (173), Expect = 6e-11 Identities = 111/501 (22%), Positives = 175/501 (34%), Gaps = 112/501 (22%) Query: 134 GPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVD 193 GP C C G CI CD DC DE G E Sbjct: 37 GP-CPASYFTCNDGFCIPMRWKCDSKADCPDMSDE------GSECAP------------- 76 Query: 194 PTFFANEDNKCRSGYTMCHSGDVCIP--XXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLS 251 KC G C CIP E NC + Sbjct: 77 ---------KCNEGQFRCGVSRHCIPNNWLCDGEFDCGKGDISDELNCPNGDTPKCRAFE 127 Query: 252 GQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSE----CARK 307 GQ + G C+ ++ C+G +C D++ C + CA Sbjct: 128 GQCRN-------------------GDCLELSRFCDGRWDC---DNDELQCDKQNAACAAL 165 Query: 308 RCDHTCMNTPHGARCIC-QEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCA 366 C C TP GARC C ++ + + C D DEC+ G C C + GS+ C C Sbjct: 166 NCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEPG-TCDQVCRNTPGSYECSCV 224 Query: 367 NGYELETDGHSCKY--EATTTPEGYLFISLGG---------EVRQMPLA----DFTDGSN 411 +GY +T G+ C+ T P +F+S G EV P A TD Sbjct: 225 SGYA-KTKGNRCRAINVPPTEPTTLIFLSRDGVQSVGTNGTEVIGPPGAKDNDKVTDKDG 283 Query: 412 YSAIQKFAGHGTIR---SIDFMHRNNKM-------------FMSISDEHGDPTGELS--V 453 + ++ +R + + HRN + + D + T S V Sbjct: 284 VGSEEELLLSQPLRFVHAFEVWHRNRTLCSLLFSWPELQMRCQRVDDARVNWTLPFSSFV 343 Query: 454 SDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQ 513 S LR +DW+ GN + + + +CT + +CR ++ +Q Sbjct: 344 SPQQFFTELR----------LDWLSGNWYLVSED---DGLVYLCTNAMTYCRVIL---QQ 387 Query: 514 GQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHD 573 L + P +G + + D R + +DGS +L+ +++ PS++ +D Sbjct: 388 VDPLSSLDLDPTKGFMFYTDWTPSLSRSL---LDGSNRTVLVTDQVYHPSSVTLDLANEL 444 Query: 574 VYFGDVERQLIERVNIDTKER 594 VY+ D+ + + RV+ + + R Sbjct: 445 VYWIDIYKDEVNRVDYEGRNR 465
Score = 66.2 bits (160), Expect = 2e-09 Identities = 48/143 (33%), Positives = 66/143 (46%), Gaps = 28/143 (19%) Query: 35 AKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCK-NGLCVANEFK 93 A F C +G CIP W+CD+ ADC DE G A C+ C + C+ N + Sbjct: 41 ASYFTCNDG--FCIPMRWKCDSKADCPDMSDE-GSECAPKCNEGQFRCGVSRHCIPNNWL 97 Query: 94 CDGEDDCRDG--SDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQ 151 CDGE DC G SDE +C P+ T P+C +CR+G C++ Sbjct: 98 CDGEFDCGKGDISDELNC-------------PNGDT-------PKCRAFEGQCRNGDCLE 137 Query: 152 PDLVCDGHQDCSGGDDEVNCTRR 174 CDG DC +DE+ C ++ Sbjct: 138 LSRFCDGRWDCD--NDELQCDKQ 158
Score = 57.0 bits (136), Expect = 1e-06 Identities = 67/261 (25%), Positives = 90/261 (34%), Gaps = 79/261 (30%) Query: 75 CSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNG 134 C S+ C +G C+ +KCD + DC D SDE GS + Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDE-------------GSECA---------- 75 Query: 135 PECHPPRLRCR-SGQCIQPDLVCDGHQDCSGGD--DEVNCTRRGHENMQSSTDFHDDVHL 191 P+C+ + RC S CI + +CDG DC GD DE+NC Sbjct: 76 PKCNEGQFRCGVSRHCIPNNWLCDGEFDCGKGDISDELNCPN------------------ 117 Query: 192 VDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLS 251 + KCR+ C +GD C+ + C + + L Sbjct: 118 -------GDTPKCRAFEGQCRNGD-CL---------------ELSRFCDGRWDCDNDEL- 153 Query: 252 GQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHC---SECARK- 307 Q D ++ AA S K P A C K+ S C EC+ Sbjct: 154 -QCDKQNAACAALNCSFNCK------LTPQGARCYCPKDQVPESSNSTRCVDYDECSEPG 206 Query: 308 RCDHTCMNTPHGARCICQEGY 328 CD C NTP C C GY Sbjct: 207 TCDQVCRNTPGSYECSCVSGY 227
Score = 48.5 bits (114), Expect = 5e-04 Identities = 84/378 (22%), Positives = 152/378 (40%), Gaps = 37/378 (9%) Query: 339 DEDECATHGHLCQHFC-EDRLGSFACKCANGYELETDGHSCKYEATTTP-EGYLFISLGG 396 D + C + C H C G+F C+C + L+ E P E L + Sbjct: 1587 DRNPCGENNGGCSHLCLLSGRGTFKCECPHVMRLDPAN-----ERNCVPNEQVLLFVMVD 1641 Query: 397 EVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDN 456 E+R + L N+ I + R IDF+ +++F SD + +S+ Sbjct: 1642 EIRGIDLHQ----PNHHTIPTI--RQSPRRIDFLVDESRIFW--SDIQQNEISSAGISNG 1693 Query: 457 GLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQS 516 + ++ N+ AVDWI N++F+ S I + G F + E S Sbjct: 1694 LIEPIINTNIEKPYGFAVDWIARNMYFS--SGQIKCNILASNLKGEFASIIHEDLNMVDS 1751 Query: 517 YRGLVVHPMRGLIIWIDSYQ--KYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDV 574 +V+ P G + WI S ++ +N+DGS ++ ++ + S L +D+ + Sbjct: 1752 ---IVLDPANGKMYWIHSASDGSMSQLEQSNLDGSSRSLIYQHENNLQS-LTMDFDSQRL 1807 Query: 575 YFGDVERQLIERVNIDTKE-RRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHH 633 Y+ + I +I E R+V++++ + + +NG LY+ + +S+ +Q Sbjct: 1808 YYA-YDNSGIAYYDIPRNETRKVLVASPITSISSLTVYNGTLYFPE-NIQSVIMQCEKEA 1865 Query: 634 HSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE----CPWLCVIVPKSDFIMTAKC 689 S+ + + + + ++ QTG SN C E C LC+ D + C Sbjct: 1866 CSNMSYLRVNTKSIQSMKMFYADAQTG--SNTCAEWAYRGGCQQLCLATSSIDHV----C 1919 Query: 690 VCPDGY-THSVTENSCIP 706 C GY C+P Sbjct: 1920 RCALGYDVEPNNPTGCVP 1937
Score = 43.5 bits (101), Expect = 0.015 Identities = 82/376 (21%), Positives = 152/376 (40%), Gaps = 48/376 (12%) Query: 350 CQHFCEDRLG-SFACKCANGYELETDGHSCKYEATTTPEGYLFIS---LGGEVRQMPLAD 405 CQ C C+CA GY++E + + ++F S L G P Sbjct: 1905 CQQLCLATSSIDHVCRCALGYDVEPNNPT----GCVPRAEFIFYSIDVLQGVEMIDPSEQ 1960 Query: 406 FTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFM------SISDEHGDPTGELSVSDN-GL 458 F S A+ + + ID++ + ++ SIS D T ++ + L Sbjct: 1961 FDTPS--PALVPISRVSSASFIDYLANTDTLYWGDNELGSISRVKRDGTQRETILEALNL 2018 Query: 459 MRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYR 518 + +++ +G +A+DW+ GN+++ S + I + + G V+ E+ + Sbjct: 2019 VGYKQQDWLG--GIAIDWVAGNIYW---SDTKRNIIEVARLDGSHRYVVVSNLEKPTA-- 2071 Query: 519 GLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLE--VPSALAIDYIRHDVYF 576 L V P++GL+ ++ I +DGSQ +L++ +L +D VY+ Sbjct: 2072 -LAVDPLQGLLFYVTQ----QHIGRVGLDGSQPFVLVNQTRANWAVGSLVLDIEATKVYW 2126 Query: 577 GDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWAD--WGSESLKVQEMTHHH 634 + + +V+ D R +++ +++P +A +LYWA+ + ++V + + Sbjct: 2127 CERYPDALMKVDYDGNLREQLLNESLNNPVALAKMGDYLYWAENKYNEGIIRVAPLANLS 2186 Query: 635 SSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE--CPWLCVIVPKSDFIMTAKCVC- 691 S V+ T + + Q G SNPC C LC+ S A C C Sbjct: 2187 QSKVVLQTEQDAIRDLKIYSKHLQRG--SNPCAHSNGACEQLCLFNGTS-----AVCACA 2239 Query: 692 -----PDGYTHSVTEN 702 DGY+ EN Sbjct: 2240 HSRLASDGYSCEPYEN 2255
Score = 38.1 bits (87), Expect = 0.55 Identities = 16/36 (44%), Positives = 21/36 (58%) Query: 302 SECARKRCDHTCMNTPHGARCICQEGYKLADDGLTC 337 S CA+ +C C+NTP GA C C +G+ L G C Sbjct: 879 SACAQSKCPGMCLNTPKGAICRCPDGFTLNGTGSHC 914
Score = 35.0 bits (79), Expect = 5.1 Identities = 33/122 (27%), Positives = 45/122 (36%), Gaps = 20/122 (16%) Query: 659 TGPPSNPCLELECP--WLCVIVPKSDFIMTAKCVCPDGYTHSVTE-----NSCIPPVTIE 711 TG C L C +C + T +C CPDG+T E + C + Sbjct: 4321 TGEQCEHCRNLTCENGGIC----RETLTGTPQCECPDGFTGKRCEIDECADFCKNGGSCV 4376 Query: 712 DEENLEKLSHIGSALMAEYCEAGVA---CMNGGACRELQNEHGRAHRIVCDCEGPYDGQY 768 ++ S E+CE+ C NGG C E R R+ C C Y G+ Sbjct: 4377 ISTKGQRQCKCPSGYFGEHCESNSCRDFCRNGGTCSE------RGGRLSCTCPPRYIGES 4430 Query: 769 CE 770 CE Sbjct: 4431 CE 4432
>gi|23600433|ref|XP_146277.2| similar to vitellogenin receptor [Periplaneta americana] [Mus musculus] Length = 1912 Score = 192 bits (488), Expect = 2e-47 Identities = 158/640 (24%), Positives = 275/640 (42%), Gaps = 108/640 (16%) Query: 75 CSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNG 134 CS+ C+NG C+++ +CDG+ DC D SDE+ C P A + Sbjct: 869 CSSPEFQCENGQCISSSLRCDGDRDCLDHSDEEGC-------------PVAWSL------ 909 Query: 135 PECHPPRLRC-RSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVD 193 +C ++C +SG+C+ + +CD DC G DE +C + V Sbjct: 910 -QCPEGEMKCPKSGECVLAEWICDHDVDCKDGTDEKDCGLK--------------VISCG 954 Query: 194 PTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQ 253 P +A C SGD C+P E C + E Sbjct: 955 PRQWA------------CDSGDQCVPDFWHCDGQSDCRDGSDEAGCAPQKCQDSE----- 997 Query: 254 ADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSE--CARKRCDH 311 + C T G C+ + C+G ++C G DE CS C+ C H Sbjct: 998 ------------FQCAT-----GACLSFSMVCDGREDCVDGSDEGGECSSSVCSPGLCYH 1040 Query: 312 TCMNTPHGARCICQEGYKLADDGLTCEDEDECAT-HGHLCQHFCEDRLGSFACKCANGYE 370 +C +P G C+C G++L +G C+D +EC G C C + GS+ C C GY Sbjct: 1041 SCYQSPTGPVCVCAPGFELESNGQICQDVNECQQPSGQPCSQTCINTEGSYICACHPGYL 1100 Query: 371 LETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFM 430 L DGH+CK T E L +S+ + L + +A + A I S+D+ Sbjct: 1101 LGPDGHTCK---ATGAEPILLVSIEFNLFLSGLRSLKEDILTTADKNLA----IYSVDYD 1153 Query: 431 HRNNKMFMSISDEHGDPTGELSVSDNGL-MRVLRENVIGVSNVAVDWIGGNVFFTQKSPS 489 + K+F + + ++ +G+ ++ ++ + IG VDWIG N+++T Sbjct: 1154 LVDQKIFWADPNAESIRWTSMATKKDGIVVQGIKPDCIG-----VDWIGRNLYWTDGRAG 1208 Query: 490 PSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGS 549 I + M + + + L + P+ GL+ W ++ ++ RI A MDGS Sbjct: 1209 QILAIQLTAMGRGKSEYTVVLDDDLIRPQSLALDPLNGLMYWSETGEE-PRIEQAGMDGS 1267 Query: 550 QVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTK--ERRVVISNG------ 601 +IL++ L P+++A+D + +++ D + I VN+D V+++ G Sbjct: 1268 SRKILVNQGLGHPTSIALDQLSWKIFWSDEKFHCIGSVNLDGSGISVSVLLTLGSVEISW 1327 Query: 602 ------VHHPYDMAYFNGFLYWADWGSESLK-VQEMTHHHSSPQVIHTFNRYPYGIAVNH 654 + P+ +A F ++W+D + +++ ++MT + V+ + P+G+ + H Sbjct: 1328 MMQLTQIKSPFSVAVFEDKVFWSDLQTRTIQHAEKMTGKDRA--VLIKRSGQPFGLKIMH 1385 Query: 655 SLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDG 694 + Q S+PCL++ C LC++ P++ C CP G Sbjct: 1386 EVLQP-RSSSPCLDIGCSHLCLLSPRA----KGSCRCPVG 1420
Score = 142 bits (357), Expect = 3e-32 Identities = 167/655 (25%), Positives = 269/655 (41%), Gaps = 107/655 (16%) Query: 61 DKGRDESGCSYAH-HCSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFD 119 D G++E C+ + + C+ + C+GE +C DG+DE CE L Sbjct: 36 DMGKEEYDVPQGELECNRTRQVACGEKCIPVAWLCNGEQECPDGTDEL-CEQTCLG---- 90 Query: 120 GSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENM 179 H +C +G+CI +CDG DC G DEVNC E++ Sbjct: 91 ------------------HLQAWQCDNGRCIPASWLCDGASDCLDGSDEVNC-----ESL 127 Query: 180 QSSTDFH----DDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXX 235 + D+ +D + C G + + Sbjct: 128 TACPDYKIRCPGKAQCLDAGEPCDAQQSCEDGSIKAYCPHI--------------RCLAG 173 Query: 236 EKNCQTNAPSEEEYLSGQADHMHSCS-AAGMYSC--GTKGSEIGVCIPMNATCNGIKECP 292 + CQ A + + DH S SC GT + G CIP + CNG +C Sbjct: 174 QWQCQNRACIMDSWRCDGIDHCGDASDERDCASCPEGTVSCDSGKCIPESLMCNGRADCT 233 Query: 293 LGDDESKHCSE-CA--RKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHL 349 G DE + C + C+ C+ C +T G RC C G++L DG +C D DEC+ Sbjct: 234 DGADEPRTCGKNCSLLNGGCEGPCSDTHWGVRCSCTPGWQLQPDGWSCGDVDECSLPYGP 293 Query: 350 CQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDG 409 C C + GS++C C G++L +G C+ T + + I+ E+R + D G Sbjct: 294 CGQLCHNTPGSYSCGCIQGHQL-YNGTDCR---VTDDDVKILIATDKELR---ILDRRTG 346 Query: 410 SNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVLRENVIGV 469 S+ I + ++ + D + RN ++ D + V L + V Sbjct: 347 SHEMLIPVKSRPSSV-AYD-LDRNMYFWV-------DKVLNVFVFGKPNSVHLYPELPPV 397 Query: 470 SNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMF-CRRVIEGKEQGQSYRGLVVHPMRGL 528 S++++DW+ G +++ + S+G IC +G+ R ++ E+ LVV P + Sbjct: 398 SSISLDWVTGQLYW-----ASSSGRVIC--AGLSDGRGYVKILEKDLVPEELVVFPAKRY 450 Query: 529 IIWID-SYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERV 587 + W+D S I A MDGS ++L E P L +D++ +Y+ ++ IE V Sbjct: 451 LYWVDRSENGVKTIETAGMDGSDRKMLAVVTAEEPLGLTLDHVTGRLYWISGYKESIETV 510 Query: 588 NIDTKER----RVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQ----V 639 N+D+ R RV + HP +A F +WA+ + Q + SSP+ + Sbjct: 511 NVDSSGRYTFPRVFFED--EHPVGLAVFENAFFWAN------QTQLIRTSPSSPKEREVL 562 Query: 640 IHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDG 694 +H I+ L++T P + C L C L I PK KCVCP+G Sbjct: 563 LHA------SISAFSVLHKTQQPKSSCSHL-C-LLSPIHPKG-----YKCVCPEG 604
Score = 71.6 bits (174), Expect = 5e-11 Identities = 50/172 (29%), Positives = 70/172 (40%), Gaps = 22/172 (12%) Query: 17 LIKNTAQAPAVNNSTCDQA-----KEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSY 71 L + P + C+Q + + C NG RCIPA W CD +DC G DE C Sbjct: 69 LCNGEQECPDGTDELCEQTCLGHLQAWQCDNG--RCIPASWLCDGASDCLDGSDEVNCES 126 Query: 72 AHHCSTSFMLCK-NGLCVANEFKCDGEDDCRDGSDEQHCEY-NILKSRFDGSN-----PS 124 C + C C+ CD + C DGS + +C + L ++ N S Sbjct: 127 LTACPDYKIRCPGKAQCLDAGEPCDAQQSCEDGSIKAYCPHIRCLAGQWQCQNRACIMDS 186 Query: 125 APTTFVGHNG--------PECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDE 168 + H G C + C SG+CI L+C+G DC+ G DE Sbjct: 187 WRCDGIDHCGDASDERDCASCPEGTVSCDSGKCIPESLMCNGRADCTDGADE 238
Score = 65.5 bits (158), Expect = 4e-09 Identities = 29/71 (40%), Positives = 41/71 (57%), Gaps = 2/71 (2%) Query: 36 KEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCD 95 +++ C +G +C+P W CD +DC G DE+GC+ C S C G C++ CD Sbjct: 956 RQWACDSGD-QCVPDFWHCDGQSDCRDGSDEAGCA-PQKCQDSEFQCATGACLSFSMVCD 1013 Query: 96 GEDDCRDGSDE 106 G +DC DGSDE Sbjct: 1014 GREDCVDGSDE 1024
Score = 47.0 bits (110), Expect = 0.001 Identities = 63/290 (21%), Positives = 116/290 (40%), Gaps = 41/290 (14%) Query: 327 GYKLADDGLTCEDEDECATHGHLCQHFC-EDRLGSFACKCANGYELETDGHSCKYEATTT 385 G K+ + L C G C H C +C+C G L DG +C + Sbjct: 1380 GLKIMHEVLQPRSSSPCLDIG--CSHLCLLSPRAKGSCRCPVGLLLADDGITC---VSLQ 1434 Query: 386 PEGYLFISLGGEVRQMPLADFTDGSNYSA----IQKFAGHGTIRSIDFMHRNNKMFMSIS 441 G++F+ L + Q+ L + + I F + S+D++ + +++S Sbjct: 1435 ESGFVFLVLPTVLTQIYLKNLKTSQQTTVPEHRILPFTSVKQLASVDYLVQEKALYLS-- 1492 Query: 442 DEHGDPTGELSVSDNGLMRVLRENVIG----------VSNVAVDWIGGNVFFTQKSPSPS 491 EL+ SD L+R+ ++ V + A+DW+ GN+++ + + Sbjct: 1493 --------ELNTSDIRLLRMKEPGILSWRRVISVKGTVIDFALDWMSGNIYWID---TDN 1541 Query: 492 AGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWI-----DSYQKYHRIMMANM 546 I++ +G + ++ E +V+HP + D + I A+M Sbjct: 1542 PYINVAFSNGQY--PIVLLSENLYRPTSIVLHPPTAAMCLADLGSQDDGRHGSSIECASM 1599 Query: 547 DGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRV 596 DGS ++L +VP LA VY+ D + LI+ + +D RV Sbjct: 1600 DGSGRKVLWLQS-QVPVGLAFSDSGTRVYWADTGQGLIQSIQLDGSRYRV 1648
>gi|126074|sp|P20063|LDLR_RABIT Low-density lipoprotein receptor (LDL receptor) gi|90078|pir||A29512 LDL receptor precursor - rabbit (fragment) gi|165456|gb|AAA31383.1| low density lipoprotein receptor precursor Length = 837 Score = 191 bits (486), Expect = 3e-47 Identities = 184/721 (25%), Positives = 285/721 (39%), Gaps = 123/721 (17%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC ++ +F CG RCIP W+CD DC+ G DE GC+ CS C G C++ Sbjct: 54 TC-KSDDFSCGGRLNRCIPGHWKCDGQQDCEDGSDELGCA-PKTCSQDEFRCAEGACISR 111 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCI 150 F CDGE DC DGSDE C AP+T C P RC S C+ Sbjct: 112 LFACDGEPDCPDGSDEASC---------------APST--------CGPAHFRCNSSSCV 148 Query: 151 QPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTM 210 CDG DC G DE + Q C Sbjct: 149 PALWACDGEPDCDDGSDEWPARCGARPSPQPGR------------------GPCSRHEFH 190 Query: 211 CHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMH-SCSAAGMYSCG 269 C SG+ C+ E++C +E+ +H S CG Sbjct: 191 CGSGE-CVHASWRCDGDADCRDGSDERDCAAATCRPDEFQCSDGTCIHGSRQCDQQQDCG 249 Query: 270 TKGSEIGV------------------CIPMNATCNGIKECPLGDDES-KHCS--ECARKR 308 E+G CI ++ CN ++C DE K C+ EC R Sbjct: 250 DMSDEVGCVNVTLCEGPDKFKCHSGECISLDKVCNSARDCQDWSDEPIKECATNECMRGN 309 Query: 309 --CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCA 366 C HTC + G C C +GY+L D CED +EC +C C + GS+ C+C Sbjct: 310 GGCSHTCFDLRIGHECHCPKGYRLVDQ-RRCEDINECED-PDICSQLCVNLAGSYKCECR 367 Query: 367 NGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRS 426 G++L+ +CK YLF + EVR+M L D S Y+++ A + + Sbjct: 368 AGFQLDPHSQACK---AVDSIAYLFFTNRHEVRKMTL----DRSEYTSL--IANLKNVVA 418 Query: 427 IDFMHRNNKMFMS-----------ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVD 475 +D +N+++ S I HG P + +S ++ +AVD Sbjct: 419 LDAEVASNRIYWSDLSQRKIYSAQIDGAHGFPAYDTVIS---------SDLQAPDGLAVD 469 Query: 476 WIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSY 535 WI G++++T S +S+ G RR +++G R +VV P G + W D + Sbjct: 470 WIHGHIYWTD---SVLGTVSVADTRGF--RRKTLFRQEGSKPRAIVVDPAHGFMYWTD-W 523 Query: 536 QKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERR 595 +I ++G V L+ ++ P+ + +D +Y+ D + I ++++ R+ Sbjct: 524 GVPAKIEKGGLNGVDVYSLVTEDIQWPNGITLDLSSGRLYWVDSKLHSISSIDVNGGNRK 583 Query: 596 VVISNG--VHHPYDMAYFNGFLYWADWGSESL---------KVQEMTHHHSSPQVIHTFN 644 V+ + + HP+ +A F ++W D +E++ V + + SP+ I F+ Sbjct: 584 TVLEDEQRLAHPFSLAIFEDKVFWTDVINEAIFSANRLTGSDVHLVAENLLSPEDIVLFH 643 Query: 645 RYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPK-SDFIMTAKCVCPDGYTHSVTENS 703 VN P C +LC+ P+ + C CPDG + S Sbjct: 644 NLTQPRGVNWCEKTALPNGG------CQYLCLPAPQINSHSPKFTCACPDGTLLAADMRS 697 Query: 704 C 704 C Sbjct: 698 C 698
>gi|24650134|ref|NP_733119.1| CG31094-PA [Drosophila melanogaster] gi|23172322|gb|AAF56499.2| CG31094-PA [Drosophila melanogaster] Length = 883 Score = 191 bits (485), Expect = 5e-47 Identities = 187/714 (26%), Positives = 296/714 (41%), Gaps = 107/714 (14%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 E+ C +G +C+P W CD DC G DE C+ C C NG C+ +KCD Sbjct: 76 EYACKSGEGQCVPLAWMCDQSKDCSDGSDEHNCN--QTCRADEFTCGNGRCIQKRWKCDH 133 Query: 97 EDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVC 156 +DDC DGSDE+ C P P V + C +G CI VC Sbjct: 134 DDDCGDGSDEKEC-------------PVVPCDSVAEH---------TCTNGACIAKRWVC 171 Query: 157 DGHQDCSGGDDEVNC---TRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSG------ 207 DG DCS G DE +C T+ + D + + ++ + D C G Sbjct: 172 DGDPDCSDGSDERSCANVTKTTTPCLSHEYQCKDRITCLHHSWLCDGDRDCPDGDDEHTA 231 Query: 208 ---YTMCHS-----GD-VCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMH 258 C + GD CIP E++C + + Sbjct: 232 NCKNVTCRADQFQCGDRSCIPGHLTCNGDKDCADGSDERDCGLSL--------SLGINQG 283 Query: 259 SCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE-SKHC--SECARKR--CDHTC 313 C+A + CG G C+P++ C+ K+CP G+DE + C +ECA K C H C Sbjct: 284 GCNATSEFDCGG-----GQCVPLSKVCDKRKDCPDGEDEPAGKCGINECASKNGGCMHQC 338 Query: 314 MNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELET 373 ++ G C C EGYKL+ D C+D +EC G C C + +G F C+C GY + Sbjct: 339 IDLKVGHHCECHEGYKLSPDKRNCQDINECEVPGK-CSQICVNEIGGFKCECEAGYMRDP 397 Query: 374 DGHS-CKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHR 432 H+ CK + L ++ ++R++ L D ++I T ++DF+ R Sbjct: 398 KNHTRCK---ASEGHASLLLARRHDIRKIAL----DHMEMTSIVNSTKAAT--ALDFVFR 448 Query: 433 NNKMFMS---ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPS 489 +F S + P E N VL ++ + +AVDWI +V+FT + Sbjct: 449 TGMIFWSDVTTQSIYKAPIDE----GNEKTVVLTKSSVTSDGLAVDWIYNHVYFTD---T 501 Query: 490 PSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGS 549 I + G + ++ K+ R + + P+ G + W D + RI A MDGS Sbjct: 502 HKCTIELTNFEGSMGKVLV--KDSLDIPRSIALDPIEGWMYWSD-WGASPRIERAGMDGS 558 Query: 550 QVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYD 607 ++ ++ P+ + +D ++ +Y+ D + +I N D +R V+ +G + HP+ Sbjct: 559 HRTTIISYDVKWPNGITLDLVKKRIYWVDGKLNVISSANYDGSQRSQVLYSGEYLRHPFS 618 Query: 608 MAYFNGFLYWADWGSESL---------KVQEMTHHH--SSPQVIHTFNRYPYGIAVNHSL 656 + F +YW DW +++ V+ +T H P V+H ++ Y VNH Sbjct: 619 ITTFEDNVYWTDWDKQAVFKANKFTGEDVEPVTAMHMLQHPMVVHVYHPYRQPDGVNHCQ 678 Query: 657 YQTGPPSNPCLELECPWLCVIVPK-SDFIMTAKCVCPDGYTHSVTENSCIPPVT 709 G C LC+ P+ ++ C CP G V C+ +T Sbjct: 679 SVNG---------HCSHLCLPAPRINERSPRISCACPTGLKLMVDGLMCVEDLT 723
>gi|476530|pir||QRRTLD LDL receptor precursor - rat Length = 879 Score = 188 bits (477), Expect = 4e-46 Identities = 182/734 (24%), Positives = 285/734 (38%), Gaps = 124/734 (16%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 ++P S ++ EF CG RCIP W+CD DC+ G DE CS CS C Sbjct: 58 ESPETCMSVTCRSGEFSCGGRVSRCIPDSWRCDGRTDCENGSDELDCS-PKTCSLDEFRC 116 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPS------------------ 124 ++G C++ +F CD + DC DGSDE HC N S Sbjct: 117 QDGKCISRQFVCDQDWDCLDGSDEAHCAATTCGPAHFRCNSSSCIPSLWACDGDRDCDDG 176 Query: 125 ---------APTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRG 175 A T C C S +CI VCDG DC DE NC Sbjct: 177 SDEWPQNCGAENTAAEVVSSPCSSLEFHCGSSECIHRSWVCDGAADCKDKSDEENCA--- 233 Query: 176 HENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXX 235 V P F D C G C C Sbjct: 234 -------------VTTCRPDEFQCADGSCIHGSRQCDREHDC-------------KDMSD 267 Query: 236 EKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGD 295 E C ++ C + C + G CI ++ CN ++C Sbjct: 268 ELGCI---------------NVTQCDGPNKFKCHS-----GECISLDKVCNSARDCRDWS 307 Query: 296 DES-KHC--SECARKR--CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLC 350 DE K C +EC C H C + G C+C G++L DG CED DEC C Sbjct: 308 DEPIKECKTNECLDNNGGCSHICKDLKIGYECLCPSGFRLV-DGHQCEDIDEC-QEPDTC 365 Query: 351 QHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGS 410 C + GSF C+C G+ ++ CK + G+L + EVR+M L D S Sbjct: 366 SQLCVNLEGSFKCECRAGFHMDPHTRVCKAVGSI---GFLLFTNRHEVRKMTL----DRS 418 Query: 411 NYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLM----RVLRENV 466 Y+++ + ++D NN+++ S + + +V D G ++ ++ Sbjct: 419 EYTSL--IPNLKNVVALDTEVANNRIYWSDLSQRKIYS---AVMDQGTSLSYDAIISGDL 473 Query: 467 IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMR 526 +AVDWI GN+++T P +S+ G+ RR +E+G R +VV P+ Sbjct: 474 HAPDGLAVDWIHGNIYWTDSVPGT---VSVADTKGV--RRRTLFREKGSRPRAIVVDPVH 528 Query: 527 GLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIER 586 G + W D + +I ++G + L+ ++ P+ + +D +Y+ D + I Sbjct: 529 GFMYWTD-WGTPAKIKKGGLNGVDIYSLVTEDIQWPNGITLDLPSGRLYWVDSKLHSISS 587 Query: 587 VNIDTKERRVVISN--GVHHPYDMAYFNGFLYWADWGSESL---------KVQEMTHHHS 635 ++++ R+ ++ + + HP+ +A + +YW D +E++ V + + Sbjct: 588 IDVNGGGRKTILEDEKQLAHPFSLAIYEDKVYWTDVLNEAIFSANRLTGSDVNLVAKNLM 647 Query: 636 SPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPK-SDFIMTAKCVCPDG 694 SP+ I F+ VN P C ++C+ P+ S C CPDG Sbjct: 648 SPEDIVLFHNVTQPRGVNWCEATVLPNGG------CQYMCLPAPQISAHSPKFTCACPDG 701 Query: 695 YTHSVTENSCIPPV 708 + SC+P V Sbjct: 702 MLLAKDMRSCLPEV 715
>gi|547842|sp|P35952|LDLR_RAT Low-density lipoprotein receptor precursor (LDL receptor) gi|56570|emb|CAA32001.1| LDL-receptor precursor (AA -21 to 879) [Rattus norvegicus] Length = 879 Score = 188 bits (477), Expect = 4e-46 Identities = 183/734 (24%), Positives = 289/734 (39%), Gaps = 124/734 (16%) Query: 23 QAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLC 82 ++P S ++ EF CG RCIP W+CD DC+ G DE CS CS C Sbjct: 58 ESPETCMSVTCRSGEFSCGGRVSRCIPDSWRCDGRTDCENGSDELDCS-PKTCSLDEFRC 116 Query: 83 KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSA--PTTFVGHN------- 133 ++G C++ +F CD + DC DGSDE HC N S+ P+ + Sbjct: 117 QDGKCISRQFVCDQDWDCLDGSDEAHCAATTCGPAHFRCNSSSCIPSLWACDGDRDCDDG 176 Query: 134 --------GPE----------CHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRG 175 G E C C S +CI VCDG DC DE NC Sbjct: 177 SDEWPQNCGAEDTAAEVVSSPCSSLEFHCGSSECIHRSWVCDGAADCKDKSDEENCA--- 233 Query: 176 HENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXX 235 V P F D C G C C Sbjct: 234 -------------VTTCRPDEFQCADGSCIHGSRQCDREHDC-------------KDMSD 267 Query: 236 EKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGD 295 E C ++ C + C + G CI ++ CN ++C Sbjct: 268 ELGCI---------------NVTQCDGPNKFKCHS-----GECISLDKVCNSARDCRDWS 307 Query: 296 DES-KHC--SECARKR--CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLC 350 DE K C +EC C H C + G C+C G++L DG CED DEC C Sbjct: 308 DEPIKECKTNECLDNNGGCSHICKDLKIGYECLCPSGFRLV-DGHQCEDIDEC-QEPDTC 365 Query: 351 QHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGS 410 C + GSF C+C G+ ++ CK + G+L + EVR+M L D S Sbjct: 366 SQLCVNLEGSFKCECRAGFHMDPHTRVCKAVGSI---GFLLFTNRHEVRKMTL----DRS 418 Query: 411 NYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLM----RVLRENV 466 Y+++ + ++D NN+++ S + + +V D G ++ ++ Sbjct: 419 EYTSL--IPNLKNVVALDTEVANNRIYWSDLSQRKIYS---AVMDQGTSLSYDAIISGDL 473 Query: 467 IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMR 526 +AVDWI GN+++T P +S+ G+ RR +E+G R +VV P+ Sbjct: 474 HAPDGLAVDWIHGNIYWTDSVPGT---VSVADTKGV--RRRTLFREKGSRPRAIVVDPVH 528 Query: 527 GLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIER 586 G + W D + +I ++G + L+ ++ P+ + +D +Y+ D + I Sbjct: 529 GFMYWTD-WGTPAKIKKGGLNGVDIYSLVTEDIQWPNGITLDLPSGRLYWVDSKLHSISS 587 Query: 587 VNIDTKERRVVISN--GVHHPYDMAYFNGFLYWADWGSESL---------KVQEMTHHHS 635 ++++ R+ ++ + + HP+ +A + +YW D +E++ V + + Sbjct: 588 IDVNGGGRKTILEDEKQLAHPFSLAIYEDKVYWTDVLNEAIFSANRLTGSDVNLVAKNLM 647 Query: 636 SPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPK-SDFIMTAKCVCPDG 694 SP+ I F+ VN P C ++C+ P+ S C CPDG Sbjct: 648 SPEDIVLFHNVTQPRGVNWCEATVLPNGG------CQYMCLPAPQISAHSPKFTCACPDG 701 Query: 695 YTHSVTENSCIPPV 708 + SC+P V Sbjct: 702 MLLAKDMRSCLPEV 715
>gi|547839|sp|Q99088|LDL2_XENLA Low-density lipoprotein receptor 2 precursor (LDL receptor 2) gi|214578|gb|AAA49898.1| low density lipoprotein receptor-2 Length = 892 Score = 187 bits (474), Expect = 8e-46 Identities = 189/713 (26%), Positives = 308/713 (43%), Gaps = 94/713 (13%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC A +F CG RCIP W+CD DC+ G DE+ C+ C+ C++G C++ Sbjct: 67 TCG-ADQFSCGGRLNRCIPMSWKCDGQTDCENGSDENDCT-RKVCADDQFTCRSGKCISL 124 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCR-SGQC 149 +F CD + DC DGSDE +C P C+P +C+ G C Sbjct: 125 DFVCDQDQDCDDGSDESYCP-----------------------APTCNPAMFQCKDKGIC 161 Query: 150 IQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSST-----DFH----DDVHLVDPTFFANE 200 I CDG +DC G DE +C G E +++ +FH + +H+ Sbjct: 162 IPKLWACDGDRDCEDGSDEDHC--EGREPIKTDKPCAPLEFHCGSGECIHM--------- 210 Query: 201 DNKCRSGYTMCHSGD--VCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQAD--H 256 KC +GY H D C+ + Q + + + LS + + Sbjct: 211 SWKCDAGYDCKHKSDDKDCVKPTCRPDQFQCNDGTCIHGSRQCDREYDCKDLSDEEGCVN 270 Query: 257 MHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDES-KHC--SECARKR--CDH 311 + C ++ C + G CI M+ C+ ++C DE K C +EC R C H Sbjct: 271 VTKCQGPDVFKCRS-----GECITMDKVCHKKRDCRDWTDEPIKECGENECLRNNGGCSH 325 Query: 312 TCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYEL 371 C + G C+C EGY+L D CED +EC + + C C + G + C+C GY++ Sbjct: 326 ICNDLKIGYECLCNEGYRLVDQK-RCEDINEC-ENPNTCTQICINLHGGYKCECREGYQM 383 Query: 372 ETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMH 431 + SCK T YLF + EVR+M L D S Y++ + ++D Sbjct: 384 DPVTASCKSIGTV---AYLFFTNRHEVRKMTL----DRSEYTSF--IPRLKNVVALDMEI 434 Query: 432 RNNKMFMSISDEHGDPTGELSVSDNGLMR--VLRENVIGVSNVAVDWIGGNVFFTQKSPS 489 +NK++ S + + + +DN V+ + +AVDWI GN+++T S Sbjct: 435 ASNKIYWSDLTQRKIYSASMDKADNTSHHETVISNQIQAPDGIAVDWIHGNIYWTD---S 491 Query: 490 PSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGS 549 + IS+ G +R + R +VV P +G + W D + +I ++G Sbjct: 492 KFSTISVANTEG--SKRKTLFTDDLAKPRDIVVDPSQGFMYWTD-WGLPAKIEKGGLNGV 548 Query: 550 QVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVH--HPYD 607 L+ + +E P+ + +D I +Y+ D + + ++I + RR V+S+ H HP+ Sbjct: 549 DRYPLVTDNIEWPNGITLDLISQRLYWVDSKLHSLSCIDITGENRRTVLSDETHLAHPFG 608 Query: 608 MAYFNGFLYWADWGSESL-KVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPC 666 + F ++W D +E++ + +T + H + P I + H+L Q P + Sbjct: 609 LTIFEDLVFWTDIENEAIFSAKRLTGENIMKVAEHLLS--PEDIVLYHNLRQ--PKAENW 664 Query: 667 LELE------CPWLCVIVPKSDFIMTA-KCVCPDGYTHSVTENSCIP-PVTIE 711 E C +LC+ P + C CPDG +C+ PVT E Sbjct: 665 CESHHLGNGGCGYLCLPAPHVNARSPKFTCACPDGMHLGTDMRNCMKEPVTQE 717
>gi|1389559|gb|AAB02882.1| glycoprotein 330 Length = 1751 Score = 186 bits (472), Expect = 1e-45 Identities = 181/741 (24%), Positives = 293/741 (39%), Gaps = 99/741 (13%) Query: 32 CDQAKEFDCGNGRLRCIPAEWQCDNVADC--DKGRDESGCSYAHHCSTSFMLCKNG-LCV 88 C+ EF C N RCIP E+ C+ V +C + DE C C + + C N +C+ Sbjct: 76 CNATTEFMCNN--RRCIPREFICNGVDNCHDNNTSDEKNCP-DRTCQSGYPKCHNSNICI 132 Query: 89 ANEFKCDGEDDCRDGSDEQ--HC--------------------EYNILKSRFDGSNPSAP 126 + CDG++DC D SDE +C + I D + S Sbjct: 133 PRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQTFGICDQETDCFDASDE 192 Query: 127 TTFVGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSS---- 182 + GH+ C +C G+CI + +CDG DC DE + ++N S Sbjct: 193 PSSCGHSERTCLSDEFKCDGGRCIPNEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFPC 252 Query: 183 -TDFHDDVHLVDPTFFANEDNKCRSGYT--------MCHSGD------VCIPXXXXXXXX 227 D D + ++ + D C G+ C + +CIP Sbjct: 253 VNDRPPDRRCIPQSWPPDGDVDCTDGHDEIQNCTRRTCSENEFTCGYGLCIPKIFRCDRH 312 Query: 228 XXXXXXXXEKNCQTNAPSEEEYLSGQA---------DHMHSCSAAG---MYSCGTK---- 271 E+ C + ++ D + C M+ C T Sbjct: 313 NDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTC 372 Query: 272 -----GSEIGVCIPMNATCNGIKECPLGDDES----KHCSECARKRCDHTCMNTPHGARC 322 + G CI M CN + +C DE C + + CDH C +T C Sbjct: 373 PPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGCGINECHDPSISGCDHNCTDTLTSFYC 432 Query: 323 ICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEA 382 C+ GYKL D TC D DEC +C CE+ +GS+ CKCA GY E DG +C+ + Sbjct: 433 SCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTCRQNS 492 Query: 383 TTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISD 442 P YL S +R + + DG YS I G + ++DF +++ D Sbjct: 493 NIEP--YLIFSNRYYLRNLTI----DGYFYSLI--LEGLDNVVALDFDRVEKRLYW--ID 542 Query: 443 EHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSG- 501 + ++ ++ + ++AVDW+ +++ G+ + ++G Sbjct: 543 TQRQVIERMFLNKTNKETIINHRLPAAESLAVDWVSRKLYWLDARLD---GLFVSDLNGG 599 Query: 502 ---MFCRRVIEGKEQ--GQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLD 556 M + ++ + RGL +HP G + W D + + I MDG+ +++ Sbjct: 600 HRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAY-IGRVGMDGTNKSVIIS 658 Query: 557 NKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLY 616 KLE P+ + IDY +Y+ D IE +++ R V + HP+ + F +Y Sbjct: 659 TKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIY 718 Query: 617 WADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE--CPWL 674 W DW + +++ + +++T +R P+ I V H Y+ SNPC C L Sbjct: 719 WTDWNTRTVEKGNKYDGSNRQTLVNTTHR-PFDIHVYHP-YRQPIVSNPCGTNNGGCSHL 776 Query: 675 CVIVPKSDFIMTAKCVCPDGY 695 C+I P C CPD + Sbjct: 777 CLIKPGGKGF---TCECPDDF 794
Score = 145 bits (367), Expect = 2e-33 Identities = 194/813 (23%), Positives = 314/813 (38%), Gaps = 152/813 (18%) Query: 32 CDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANE 91 CD EF C RCIP C+ V DC DE GC CKN C+ Sbjct: 975 CDNFTEFSCKT-NYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPLR 1033 Query: 92 FKCDGEDDCRDGSDEQHCE-YNILKSRFDGSNPSA-PTTFV--------GHNGPE----- 136 +KCDG++DC D SDE++C +S F N P+ ++ G N E Sbjct: 1034 WKCDGQNDCGDNSDEENCAPRECTESEFRCVNQQCIPSRWICDHYNDLWGDNSDERDCEM 1093 Query: 137 --CHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHD------- 187 CHP +C SG + +L CDG DC DE +C R + + Sbjct: 1094 RTCHPEYFQCTSGHRVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCI 1153 Query: 188 ------------------------DVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXX 223 DV P F ++N+C + +C+ D C Sbjct: 1154 PPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDC------ 1207 Query: 224 XXXXXXXXXXXXEKNCQTNAPSE-EEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMN 282 E++C+ P EY Y CG G CIP + Sbjct: 1208 -----GDGTDETEEHCRKPTPKPCTEY---------------EYKCGN-----GHCIPHD 1242 Query: 283 ATCNGIKEC-----PLGDDESKHCSECARKRCDHTCMNTPHGAR-CICQEGYKL-ADDGL 335 C+ +C LG ++ K CA C+ C G C C G++ D Sbjct: 1243 NVCDDADDCGDWSDELGCNKGKE-RTCAENICEQNCTQLNEGGFICSCTAGFETNVFDRT 1301 Query: 336 TCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETD--GHSCKYEATTTPEGYLFIS 393 +C D +EC G QH C + GS+ C CA+G+ +D G C E ++ L + Sbjct: 1302 SCLDINECEQFGTCPQH-CRNTKGSYECVCADGFTSMSDRPGKRCAAEGSSP---LLLLP 1357 Query: 394 LGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSI----SDEHGDPTG 449 +R+ L+ S Y +++ I+++D+ + +S+ G G Sbjct: 1358 DNVRIRKYNLSS-ERFSEYLQDEEY-----IQAVDYDWDPEDIGLSVVYYTVRGEGSRFG 1411 Query: 450 ELSVS-----DNGLMRVLRE------NVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICT 498 + + ++G +++E V+ +AVDW+G ++++ S + I + Sbjct: 1412 AIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYW---SDVKNKRIEVAK 1468 Query: 499 MSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNK 558 + G + + +I + + V+P GL+ W D + K ++ A M+G IL+ Sbjct: 1469 LDGRYRKWLISTDLDQPA--AIAVNPKLGLMFWTD-WGKEPKLESAWMNGEDPNILVFED 1525 Query: 559 LEVPSALAIDYIRHD-VYFGDVERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYW 617 L P+ L+IDY+ +D +Y+ D + +IE + D +RRV+ + +PY + F LYW Sbjct: 1526 LGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEAM-NPYSLDIFEDQLYW 1584 Query: 618 ADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVI 677 + Q + + N + + + H L N C ++ C LC++ Sbjct: 1585 ISKEKGEVWKQNKFGQGKKEKTL-VVNPWLTQVRIFHQLRYNKSVPNLCKQI-CSHLCLL 1642 Query: 678 VPKSDFIMTAKCVCPDGYTHSVTENSCIPPVTIEDEENLEKLSHIGSALMAEYCEAGVAC 737 P C CP G +S I T E + +E ++ C Sbjct: 1643 RPGG-----YSCACPQG-------SSFIEGSTTECDAAIELPINLPPP---------CRC 1681 Query: 738 MNGGACRELQNEHGRAHRIVCDCEGPYDGQYCE 770 M+GG C + + + C C Y G+YCE Sbjct: 1682 MHGGNCYFDETDLPK-----CKCPSGYTGKYCE 1709
Score = 89.0 bits (219), Expect = 3e-16 Identities = 83/297 (27%), Positives = 117/297 (39%), Gaps = 86/297 (28%) Query: 38 FDCGNGRLRCIPAEWQCDNVADCDKGRD--ESGCSYAHHCSTSFMLCKNGLCVANEFKCD 95 F C NG RCI EW+CDN C G D ES C+ H CS + C NG CV ++CD Sbjct: 1 FTCSNG--RCISEEWKCDNDNGCGDGSDEMESVCAL-HTCSPTAFTCANGRCVQYSYRCD 57 Query: 96 GEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLV 155 +DC DGSDE C + + +A T F+ C + +CI + + Sbjct: 58 YYNDCGDGSDETGCLFR---------DCNATTEFM-------------CNNRRCIPREFI 95 Query: 156 CDGHQDCSGGD--DEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHS 213 C+G +C + DE NC D C+SGY CH+ Sbjct: 96 CNGVDNCHDNNTSDEKNCP----------------------------DRTCQSGYPKCHN 127 Query: 214 GDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKGS 273 ++CIP + +C N+ Y + H+CS++ + C + Sbjct: 128 SNICIP---------RVYLCDGDNDCGDNSDENPTYCT-----THTCSSS-EFQCAS--- 169 Query: 274 EIGVCIPMN-ATCNGIKECPLGDDESKHCSECARKRCDHTCMNTP---HGARCICQE 326 G CIP C+ +C DE C R TC++ G RCI E Sbjct: 170 --GRCIPQTFGICDQETDCFDASDEPSSCGHSER-----TCLSDEFKCDGGRCIPNE 219
Score = 66.2 bits (160), Expect = 2e-09 Identities = 81/317 (25%), Positives = 107/317 (33%), Gaps = 86/317 (27%) Query: 37 EFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDG 96 +F C N +CIP W+CD DC G DE C C +G C + + C+ Sbjct: 813 QFLCANNE-KCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQCSDGNCTSPQTLCNA 871 Query: 97 EDDCRDGSDEQH--CEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDL 154 +C DGSDE CE + C +C + +CI Sbjct: 872 HQNCPDGSDEDRLLCENH-----------------------HCDSNEWQCANKRCIPESW 908 Query: 155 VCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSG 214 CD DC DE D H T CR G C +G Sbjct: 909 QCDSFNDCEDNSDE------------------DSSHCASRT--------CRPGQFRCANG 942 Query: 215 DVCIPXXXXXXXXXXXXXXXXEKNC--QTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKG 272 CIP + +C ++ P EE S H C +SC T Sbjct: 943 R-CIP---------QAWKCDVDNDCGDHSDEPIEECMSSA-----HLCDNFTEFSCKTNY 987 Query: 273 SEIGVCIPMNATCNGIKECPLGDDES----KHCSECARKRC-DHTCMNTPHGARCICQEG 327 CIP A CNG+ +C DE + C RC +H C+ P +C Q Sbjct: 988 R----CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRCKNHHCI--PLRWKCDGQ-- 1039 Query: 328 YKLADDGLTCEDEDECA 344 +D DE+ CA Sbjct: 1040 ----NDCGDNSDEENCA 1052
Score = 40.8 bits (94), Expect = 0.095 Identities = 60/237 (25%), Positives = 82/237 (34%), Gaps = 66/237 (27%) Query: 135 PECHPPRLRCRSGQ-CIQPDLVCDGHQDCSGGDDEVN-CTRRGHENMQSSTDFHDDVHLV 192 P C + C + + CI CDG +DCS G DE+ C +R Sbjct: 807 PMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQR------------------ 848 Query: 193 DPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAP--SEEEYL 250 CR G C G+ P N N P S+E+ L Sbjct: 849 ----------FCRLGQFQCSDGNCTSPQTLC--------------NAHQNCPDGSDEDRL 884 Query: 251 SGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCD 310 + H S + C K CIP + C+ +C DE S CA + C Sbjct: 885 LCENHHCDS----NEWQCANKR-----CIPESWQCDSFNDCEDNSDEDS--SHCASRTCR 933 Query: 311 HTCMNTPHGARCICQEGYKLADDGL---TCEDEDECATHGHLCQHFCEDRLGSFACK 364 +G RCI Q D+ + E +EC + HLC +F E F+CK Sbjct: 934 PGQFRCANG-RCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTE-----FSCK 984
>gi|7508146|pir||T29764 hypothetical protein T21E3.3 - Caenorhabditis elegans Length = 2180 Score = 185 bits (469), Expect = 3e-45 Identities = 189/718 (26%), Positives = 286/718 (39%), Gaps = 113/718 (15%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 +CD +F C R C+P WQCD DC G DE C S F + C+ Sbjct: 148 SCDAKTQFACLATR-TCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPL 206 Query: 91 EFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCI 150 E KCDG DC DG DE CE + G N + RC + +CI Sbjct: 207 EQKCDGRRDCPDGEDEHQCE---TECDSKGGNAT-----------------FRCTNHRCI 246 Query: 151 QPDLVCDGHQDC-----SGGDDEVNCTRRGHENMQSSTDFHDDVHLV------------- 192 CDG DC S G DEV+C G + + D+ +V Sbjct: 247 PMAWRCDGTDDCMDNAKSLGSDEVDCA-AGRTSFHVPSRCADETCVVACELTAVLCDGIQ 305 Query: 193 ------DPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXE--KNCQTNAP 244 D A+ D +C+ MC SG CI E + C + P Sbjct: 306 DCSDGFDEKNCASLDRQCKPNEWMCDSGQ-CIDSGRLCDASVDCVDGSDEWVEICSLSEP 364 Query: 245 SEEEYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE-----SK 299 SG +SC IG C+ C+G ++C G DE Sbjct: 365 PRRGCPSG-------------WSCLLTNGTIG-CLQEQQLCDGRRDCMSGIDEQCDNPQG 410 Query: 300 HCSECARKRCDHT--CMNTPHGARCICQEGYKLAD-DGLTCEDEDECATHGHLCQHFCED 356 +CS R CD T C C C +GY L+ D TC C C HFC D Sbjct: 411 NCSS-TRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKAN--CSHFCID 467 Query: 357 RLG-SFACKCANGYELETDGHSCKYEATTTPEGYL-------FISLGGEVRQMPLADFTD 408 R C CA GY L + C+ T E + ++ G + L++ T+ Sbjct: 468 RRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTN 527 Query: 409 GSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDN-GLMRVLRE-NV 466 G ++D+ +++ ++ + G+ G S+S+ RV+ Sbjct: 528 GV---------------ALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPT 572 Query: 467 IGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMR 526 G+ +AVDW+G N+++T ++ I++C M G F R +++G R +V+ P++ Sbjct: 573 KGIDGIAVDWLGRNIYYTDRNHD---AIAVCDMRGRFNRILLKGTPLNDP-RAIVLDPLQ 628 Query: 527 GLIIWIDSYQKYHRIMMANMDGSQVRILL-DNKLEVPSALAIDYIRHDVYFGDVERQLIE 585 L+ W D H I NMDGS +++L D + P+ALA+D +YFGD R I Sbjct: 629 ALVFWTDWGASAH-IGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIA 687 Query: 586 RVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNR 645 N D +RR+V+ V H + +A F ++YW+DW + +++ + +I Sbjct: 688 SCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQY 747 Query: 646 YPYGIAVNHSLYQT----GPPSNPCLE-LECPWLCVIVPKSDFIMTA---KCVCPDGY 695 P G + H Q+ +PC + C LC+ D ++ C+C G+ Sbjct: 748 RPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF 805
Score = 110 bits (276), Expect = 7e-23 Identities = 182/772 (23%), Positives = 277/772 (35%), Gaps = 138/772 (17%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGL-- 86 N C +A +F CG+ + +CIP CD DCD G DE C C F C NG Sbjct: 905 NFECTEA-QFKCGDKK-KCIPLTSVCDKEKDCDDGSDELNCEIT-SCKPDFFACFNGTAI 961 Query: 87 --CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRC 144 C+ EF CDGEDDC +G DE + I EC + +C Sbjct: 962 SKCIPKEFYCDGEDDCPEGQDEPDSCFGI---------------------GECTHEQFQC 1000 Query: 145 RSGQCIQPDLVCDGHQDCSGGDDEVNCTRR-----------------GHENMQSSTDFHD 187 SG+CI CDG DC G DE C + G + +D D Sbjct: 1001 TSGKCIPKRRQCDGTLDCRDGSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDGSD-ED 1059 Query: 188 DVHLVDPTFFANEDNKCR----SGYTMCHSGD-----------VCIPXXXXXXXXXXXXX 232 + V E+ KC G C G + Sbjct: 1060 EEACVIKQLLEKENRKCGGFACDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSS 1119 Query: 233 XXXEKNCQTNAPSEEEYLSGQA-DHMHSCSAAGMYSCGTKGSEI-GVCIPMNATCNGIKE 290 E NC N S S Q C G + C E +C A C I Sbjct: 1120 GKDENNCHNNGESNFFQCSMQTIKEWQVCD--GRWDCADGLDESPEMCASRKARCFRIGY 1177 Query: 291 CPLGDDESKHCSECARKRCD--HTCMN----TPHGARCICQEGYKLA-----DDGLTCED 339 C D+ K C + + CD C + P + +C+ Y+ D C+ Sbjct: 1178 C----DDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARCDG 1233 Query: 340 EDECA------THGHLCQHF--CEDRL-----GSFACKCANGY-ELETDGHSCKYEATTT 385 D+C T G C HF C + + C CA GY + D + C+ + Sbjct: 1234 RDDCGDGSDEDTCGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECE---PLS 1290 Query: 386 PEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHG 445 +FI+ G + M L + + S + + IDF + + + + G Sbjct: 1291 KSAEMFITNGNRLHLMSLEN-SQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIG 1349 Query: 446 DPTGELSVS--DNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSP-------SAGISI 496 + ++ +GL+ E + D++ NV+FT+ S A I + Sbjct: 1350 NSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYV 1409 Query: 497 CTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQV----- 551 R +I + L V P++ LI W S RI+ AN+DG + Sbjct: 1410 AKAKDTSTRTLIVNST--GTINSLAVDPIKRLIFWTTS-APVPRILSANLDGKPIAQPFK 1466 Query: 552 ------RILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGV-HH 604 + L++ + P+++ +D+ +Y+ DV ++ IE V+ D ++RR V + Sbjct: 1467 TGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDT 1526 Query: 605 PYDMAYFNGFLYWADWGSESLKVQEMTHHHS---------SPQVIHTFNRYPYGIAVNHS 655 P M G++Y ++ + T + SP+ I +P V+H Sbjct: 1527 PVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKIREVSPR-IQIRVAHPAKHTVSHI 1585 Query: 656 LYQTGPPSNPCLELECPWLCVIVPKSDF--IMTAKCVCPDGYTHSVTENSCI 705 +Q NPC CP V VP D I+ KC+C G V+ C+ Sbjct: 1586 THQ----KNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCM 1633
Score = 83.6 bits (205), Expect = 1e-14 Identities = 80/291 (27%), Positives = 112/291 (38%), Gaps = 69/291 (23%) Query: 38 FDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGE 97 F+CGNG CIP + C+ + DC DES C+ C+ + C++G C+ ++ +C+ Sbjct: 20 FNCGNG--LCIPEQKVCNRINDCANFADESNCT----CNENEFRCQSGACIPSKARCNHM 73 Query: 98 DDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCD 157 DC D SDE C + N SA F C + QCI P CD Sbjct: 74 QDCNDASDEIGCPFR---------NCSALNEFGMTGLINC------ATTSQCIHPSWKCD 118 Query: 158 GHQDCSGGDDEVNC-----TRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCH 212 G DC G DE +C G + S D T FA C Sbjct: 119 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCD--------AKTQFA------------CL 158 Query: 213 SGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCGTKG 272 + C+P EKNC + E+ SC ++ Sbjct: 159 ATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEF---------SCESSKK------- 202 Query: 273 SEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTPHGARCI 323 CIP+ C+G ++CP G+DE + +EC K + T T H RCI Sbjct: 203 -----CIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNH--RCI 246
Score = 82.0 bits (201), Expect = 4e-14 Identities = 92/352 (26%), Positives = 129/352 (36%), Gaps = 82/352 (23%) Query: 18 IKNTAQAPAVNNSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCST 77 I + A +N TC++ EF C +G CIP++ +C+++ DC+ DE GC + +CS Sbjct: 37 INDCANFADESNCTCNE-NEFRCQSG--ACIPSKARCNHMQDCNDASDEIGCPF-RNCSA 92 Query: 78 SFMLCKNGL--------CVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTF 129 GL C+ +KCDG +DC DGSDE+ C ++ G + SAP + Sbjct: 93 LNEFGMTGLINCATTSQCIHPSWKCDGTNDCYDGSDEKDC---FVEFDATGGSVSAPRSC 149 Query: 130 VGHNGPECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDV 189 C R C+ CDG DC+ G DE NC + Sbjct: 150 DAKTQFACLATR------TCMPKHWQCDGQPDCADGSDEKNCDAK--------------- 188 Query: 190 HLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEY 249 KC S C S CIP E C+T S+ Sbjct: 189 -------------KCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK--- 232 Query: 250 LSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKEC-----PLGDDE----SKH 300 + C CIPM C+G +C LG DE + Sbjct: 233 -----------GGNATFRCTNHR-----CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGR 276 Query: 301 CSECARKRC-DHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQ 351 S RC D TC+ +C +G + DG DE CA+ C+ Sbjct: 277 TSFHVPSRCADETCVVACELTAVLC-DGIQDCSDGF---DEKNCASLDRQCK 324
Score = 66.2 bits (160), Expect = 2e-09 Identities = 99/394 (25%), Positives = 139/394 (35%), Gaps = 100/394 (25%) Query: 21 TAQAPAVNNSTCDQAKEFDCGNGRLRCIPAE-----WQCDN-VADCDKGRDESGCSYAHH 74 TA+ P + CD CIPA DN C +G G S Sbjct: 767 TARHPCSQPARCDNL-----------CIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSE 815 Query: 75 CSTSFMLC-KNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHN 133 C + +C K C+++ ++CDG+DDC DG DE + +G P P Sbjct: 816 CKPNDFVCTKTYKCISSWWRCDGQDDCGDGEDEGYF--------VEGVCPPFP------- 860 Query: 134 GPECHPPRLRC------RSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHD 187 C + C + QC+ +CDG +DCSGGDDE Sbjct: 861 ---CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDE------------------- 898 Query: 188 DVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPS-- 245 +P F E+ +C C CIP E NC+ + Sbjct: 899 -----EPAFC--ENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPD 951 Query: 246 ---------------EEEYLSGQ------ADHMHSCSAAGMYSCGTKGSEIGVCIPMNAT 284 +E Y G+ D SC G + G CIP Sbjct: 952 FFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQ 1011 Query: 285 CNGIKECPLGDDESKHCSECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECA 344 C+G +C G DE ECA CD++C++ A +C +G K +DG + EDE+ C Sbjct: 1012 CDGTLDCRDGSDEKGCKKECA-IVCDNSCVH----ADDLC-DGKKKCNDG-SDEDEEACV 1064 Query: 345 THGHLCQHFCEDRLGSFACKCANGYELETDGHSC 378 L + + G FAC E +D C Sbjct: 1065 IKQLLEKE--NRKCGGFACDGIVDCEDGSDEKGC 1096
Score = 65.5 bits (158), Expect = 4e-09 Identities = 68/294 (23%), Positives = 103/294 (35%), Gaps = 67/294 (22%) Query: 75 CSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNG 134 C + C NGLC+ + C+ +DC + +DE +C Sbjct: 15 CRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC------------------------- 49 Query: 135 PECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDP 194 C+ RC+SG CI C+ QDC+ DE+ C R N + +F Sbjct: 50 -TCNENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFR---NCSALNEFG-------- 97 Query: 195 TFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQA 254 +G C + CI EK+C E + G Sbjct: 98 ----------MTGLINCATTSQCIHPSWKCDGTNDCYDGSDEKDCFV----EFDATGGSV 143 Query: 255 DHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCM 314 SC A ++C + C+P + C+G +C G DE C K+C Sbjct: 144 SAPRSCDAKTQFACLATRT----CMPKHWQCDGQPDCADGSDEKN----CDAKKCTSFEF 195 Query: 315 NTPHGARCICQEGYKLADDGLTCED-EDECATHGHLCQHFCEDRLGSFACKCAN 367 + +CI E + D C D EDE H C+ C+ + G+ +C N Sbjct: 196 SCESSKKCIPLE--QKCDGRRDCPDGEDE-----HQCETECDSKGGNATFRCTN 242
>gi|2118675|pir||JC4858 VLDL receptor precursor - African clawed frog gi|2366773|dbj|BAA22145.1| vitellogenin receptor [Xenopus laevis] Length = 869 Score = 184 bits (468), Expect = 4e-45 Identities = 188/741 (25%), Positives = 297/741 (40%), Gaps = 103/741 (13%) Query: 30 STCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVA 89 +T + +F CGNG RCI + W+CD DC G DES C C+ S +C+NG CV Sbjct: 29 TTLCEESQFQCGNG--RCITSLWKCDGDEDCSDGSDESSC-VKKTCAESDFVCRNGQCVP 85 Query: 90 NEFKCDGEDDCRDGSDE--QHCEYNILKS-----------------RFDGSNPSAPTTFV 130 + ++CDG+ DC DGSDE + C ++ + DG A Sbjct: 86 SRWECDGDPDCEDGSDETPELCYMRTCRATEISCGVRSTQCIPLSWKCDGERDCANAEDE 145 Query: 131 GHNGP-ECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNC---TRRGHE--------- 177 + G C P C SG+CI VC+G DCS G DEVNC T HE Sbjct: 146 ENCGNITCSPSEFTCSSGRCISSTFVCNGQNDCSDGSDEVNCVPPTCGAHEFQCKNFSCI 205 Query: 178 ------NMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXX 231 + + H D L +C + C SG+ CI Sbjct: 206 PLSWVCDDEPDCADHSDESLEQCGRQPIAPQRCSANEMPCGSGE-CIHKKWRCDGDADCK 264 Query: 232 XXXXEKNCQTNAPSEEEYLSGQADHMH------------------------SCSAAGMYS 267 E NC + +++ + +H CS G + Sbjct: 265 DKSDEINCPSRTCQPDQFKCEDGNCIHGSRQCDGVRDCLDGTDEIRCKNVIQCSVPGKFK 324 Query: 268 CGTKGSEIGVCIPMNATCNGIKEC------PLGDDESKHCSECARKRCDHTCMNTPHGAR 321 C + G CI N CN K+C P+ D E C E C H C + P G Sbjct: 325 CKS-----GECIESNKVCNKHKDCKDWSDEPVKDCEVDECLE-NNGGCSHICHDLPIGYE 378 Query: 322 CICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYE 381 C C G+KL D TC D DEC + +C C + G + C+C+ GY+++ CK Sbjct: 379 CECTAGFKLIDRK-TCGDIDEC-QNPEICSQICVNLKGGYKCECSKGYQMDPSTGVCK-- 434 Query: 382 ATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSIS 441 E L + ++R++ L IQ ++D + +F + + Sbjct: 435 -AVGREPCLIFTNRRDIRKVGL------ERKEYIQLVEQLRNTVALDADIKEQSLFWADT 487 Query: 442 DEHGDPTGELSVSDN-GLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMS 500 + + G + E+V S +A+DWI N+++ + IS+ Sbjct: 488 IQKAIFRAPFDTREKVGSHVKVVEDVHSPSAIAIDWIYKNIYWID---TILKTISVSNFD 544 Query: 501 GMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLE 560 G +R + Q + V P+ G I W D + +I A M+G + L+ ++ Sbjct: 545 G--SKRKTLFSSELQDLTSIAVDPISGFIYWSDCGEP-AKIEKAGMNGIDRQQLITADVQ 601 Query: 561 VPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNG--VHHPYDMAYFNGFLYWA 618 PS +AID ++ +Y+ D + + V+++ ++RRV++ + + HP + F +YW Sbjct: 602 RPSGIAIDVVKSRLYWVDSKLHTLSSVDLNGQDRRVILKSHEFLAHPLALTIFEDRVYWI 661 Query: 619 DWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPCLELE---CPWLC 675 D +E++ +++ N I V H L Q + ++E C +LC Sbjct: 662 DGENEAIYGANKFSGQELETLVNNLND-AQDIIVYHELIQPLGINWCNEQIENGGCKYLC 720 Query: 676 VIVPK-SDFIMTAKCVCPDGY 695 + P+ SD C CPDG+ Sbjct: 721 LPAPQISDRSPKYTCACPDGF 741
>gi|4128201|gb|AAD03484.1| very low density lipoprotein receptor VLDL-R2 [Bos taurus] Length = 845 Score = 184 bits (467), Expect = 5e-45 Identities = 176/700 (25%), Positives = 285/700 (40%), Gaps = 106/700 (15%) Query: 31 TCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVAN 90 TC + E CG +CIP W+CD DC G DE C CS+ C +G C++ Sbjct: 112 TC-RINEISCGARSTQCIPVSWRCDGENDCYSGEDEENCGNV-TCSSDEFTCSSGRCISR 169 Query: 91 EFKCDGEDDCRDGSDEQHCEYNIL--KSRFDGSNPSAPTTFVGHNGPECH---------- 138 F C+G+DDC DGSDE C + S P P ++V + +C Sbjct: 170 NFMCNGQDDCSDGSDELDCAPPTVGPTSSSAAPPPCIPISWVCDDDADCSDQSDESLEQC 229 Query: 139 -----------PPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHD 187 ++C SG+CI CDG DC G DEVNC R Sbjct: 230 GRQPVIHTRCPASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSR------------- 276 Query: 188 DVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEE 247 P F ED C G C+ C+ E NC+ Sbjct: 277 ---TCRPDQFECEDGSCIHGSRQCNGIRDCV-------------DGSDEVNCK------- 313 Query: 248 EYLSGQADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDE---SKHCSEC 304 +++ C G + C + G CI ++ CN ++C DE H +EC Sbjct: 314 --------NVNQCLGPGKFKCRS-----GECIDISKVCNQKQDCRDWSDEPLKECHVNEC 360 Query: 305 ARKR--CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFA 362 C H C + G C C G++L D TC D DEC G +C C + G + Sbjct: 361 LVNNGGCSHICKDLVIGYECYCAAGFELIDRK-TCGDIDECQNPG-ICSQICINLKGGYK 418 Query: 363 CKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHG 422 C+C+ GY+++ CK E L + ++R++ L IQ Sbjct: 419 CECSRGYQMDLATGVCK---AVGKEPSLIFTNRRDIRKIGL------ERKEYIQLVEQLR 469 Query: 423 TIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRV-LRENVIGVSNVAVDWIGGNV 481 ++D K+F +D S+ D + V + +NV + +AVDW+ + Sbjct: 470 NTVALDADIAAQKLFW--ADLSQKAIFSASIDDKVVRHVKMIDNVYNPAAIAVDWVYKTI 527 Query: 482 FFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYHRI 541 ++T + S IS+ T+ G +R + + V P+ G + W D + + +I Sbjct: 528 YWTDAA---SKTISVATLDGT--KRKFLFNSDLREPASIAVDPLSGFVYWSD-WGEPAKI 581 Query: 542 MMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISN- 600 A M+G R L+ ++ P+ + +D I+ +Y+ D + ++ V+++ ++RR+V+ + Sbjct: 582 EKAGMNGFDRRALVTADIQWPNGITLDLIKGRLYWLDSKLHMLSSVDLNGQDRRIVLKSL 641 Query: 601 -GVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQT 659 + HP + F +YW D +E++ +++ N I V H L Q Sbjct: 642 EFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGSELATLVNNLND-AQDIIVYHELVQP 700 Query: 660 GPPSNPCLELE---CPWLCVIVPK-SDFIMTAKCVCPDGY 695 + ++E C +LC+ P+ +D C CP+GY Sbjct: 701 SGKNWCEEDVENGGCEYLCLPAPQINDHSPKYTCSCPNGY 740
Score = 50.1 bits (118), Expect = 2e-04 Identities = 46/209 (22%), Positives = 81/209 (38%), Gaps = 60/209 (28%) Query: 136 ECHPPRLRCRSGQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPT 195 +C + +C +G+CI CDG +DC+ G DE NC ++ Sbjct: 32 KCEANQFQCTNGRCITLLWKCDGDEDCTDGSDEKNCVKK--------------------- 70 Query: 196 FFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQAD 255 C +C++G C+P + +C+ + E Sbjct: 71 -------TCAESDFVCNNGQ-CVP---------NRWQCDGDPDCEDGSDESPEQC----- 108 Query: 256 HMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMN 315 HM +C + SCG + ++ CIP++ C+G +C G+DE ++C + TC + Sbjct: 109 HMRTCRINEI-SCGARSTQ---CIPVSWRCDGENDCYSGEDE-ENCGNVTCSSDEFTCSS 163 Query: 316 TPHGARCICQEGYKLADDGLTCEDEDECA 344 RCI + C +D+C+ Sbjct: 164 ----GRCISRN--------FMCNGQDDCS 180
>gi|1730602|sp|P98163|YL_DROME Putative vitellogenin receptor precursor (YL) gi|7512012|pir||T13171 probable vitellogenin receptor - fruit fly (Drosophila melanogaster) gi|535346|gb|AAB60217.1| vitellogenin receptor [Drosophila melanogaster] gi|1095169|prf||2107325A vitellogenin receptor Length = 1984 Score = 184 bits (466), Expect = 7e-45 Identities = 162/663 (24%), Positives = 264/663 (39%), Gaps = 83/663 (12%) Query: 75 CSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNG 134 C C++G C+ CDG DC+D SDE C+Y + Sbjct: 90 CDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDYRL--------------------- 128 Query: 135 PECHPPR-LRCRS--GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHL 191 C PP C G C+ +L+C+G +C GG+DE+NC R F D H Sbjct: 129 --CRPPHWFPCAQPHGACLAAELMCNGIDNCPGGEDELNCPVR------PGFRFGDTAHR 180 Query: 192 VDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXE----KNCQTNAPSEE 247 + C MC CIP E K + P E Sbjct: 181 M---------RSCSKYEFMCQQDRTCIPIDFMCDGRPDCTDKSDEVAGCKQAEITCPGEG 231 Query: 248 EYLS-GQADHMHSCSAAGMYSCGTKGSEIG------------------VCIPMNATCNGI 288 + G+ G+ CG E G C+ ++ C+G Sbjct: 232 HLCANGRCLRRKQWVCDGVDDCGDGSDERGCLNLCEPQKGKFLCRNRETCLTLSEVCDGH 291 Query: 289 KECPLGDDESKHC---SECARKRC--DHTCMNTP-HGARCICQEGYKLADDGLTCEDEDE 342 +C G DE+ C +C K+C C P GA C C +G++LA CED DE Sbjct: 292 SDCSDGSDETDLCHSKPDCDAKKCALGAKCHMMPASGAECFCPKGFRLAKFEDKCEDVDE 351 Query: 343 CATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMP 402 C LC CE+ G + C C GY L+ D +C+ + E + ++ M Sbjct: 352 CKEQDDLCSQGCENTSGGYRCVCDAGYLLDKDNRTCRAVVYGSKEQQPLLLYTTQMTIMG 411 Query: 403 LADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVL 462 + + + + + + AG+ + + I + + ++ + + + + + +L Sbjct: 412 M-HLREDNVRNHVYQVAGNLS-KVIGVAYDGSHIYWTNIQNEAESIVKANGDGSNAEILL 469 Query: 463 RENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVV 522 + ++AVDW+ N++F S + I++C+ G+ C ++ + R L V Sbjct: 470 TSGLDAPEDLAVDWLTQNIYF---SDNIMRHIAVCSNDGLNCAVLV--TQDVHQPRSLAV 524 Query: 523 HPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQ 582 P +GL+ W D +K I A+MDGS+ R ++ + +E P+ +A+D + +Y+ D + Sbjct: 525 WPQKGLMFWTDWGEK-PMIGRASMDGSRSRPIVSDNIEWPNGIALDMHQQRIYWVDAKLG 583 Query: 583 LIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHT 642 ++ V D RR V+ + HPY +A F LYW+DW ++S V I Sbjct: 584 SVQTVRPDGTGRRTVLDGMLKHPYGLAIFEDQLYWSDWATKS--VHACHKFSGKDHRILA 641 Query: 643 FNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTEN 702 +R Y + + H Q P C C LC++ I C CPDG + Sbjct: 642 KDRTIYAVHIYHPAKQPNSPHG-CENATCSHLCLLAEPE--IGGHSCACPDGMRLAPDHR 698 Query: 703 SCI 705 C+ Sbjct: 699 RCM 701
Score = 172 bits (436), Expect = 2e-41 Identities = 179/670 (26%), Positives = 263/670 (39%), Gaps = 79/670 (11%) Query: 40 CGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDD 99 C NG +C+ + CD DC DE C C C +G C+A ++CDG D Sbjct: 1125 CDNG--KCVDSSLVCDGTNDCGDNSDELLCEATLRCEPGMFQCGSGSCIAGSWECDGRID 1182 Query: 100 CRDGSDEQ-HCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDG 158 C DGSDE C + C P RC SGQC+ LVCDG Sbjct: 1183 CSDGSDEHDKCVHR-----------------------SCPPDMHRCLSGQCLDRSLVCDG 1219 Query: 159 HQDCSGGDDEVNC-TRRGHENMQSSTDFH---DDVHLVDPTFF-ANEDNKCRSGYTMCHS 213 H DC DE+NC T N+ + D + ++ + P+ N +C G Sbjct: 1220 HNDCGDKSDELNCGTDSSTMNISCAEDQYQCTSNLKICLPSAVRCNGTTECPRGEDEADC 1279 Query: 214 GDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADH-MHSCSAAGMYSCGTKG 272 GDVC + Q + + LS + + H+ S +S ++ Sbjct: 1280 GDVCSIYEFKCRSGRECIRREFRCDGQKDCGDGSDELSCELEKGHHNQSQIQPWSTSSRS 1339 Query: 273 -------SEIGVCIPMNATCNGIKECPLGDDESKHC-----SECARKRCDHTCMNTPHGA 320 + G C+ ++ CN +C G DE C S R+ C H C TP GA Sbjct: 1340 CRPHLFDCQDGECVDLSRVCNNFPDCTNGHDEGPKCATACRSASGRQVCQHKCRATPAGA 1399 Query: 321 RCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKY 380 C C +GY+L D +C D DEC C CE+ LG + C+C + L D SCK Sbjct: 1400 VCSCFDGYRLDADQKSCLDIDECQEQ-QPCAQLCENTLGGYQCQCHADFMLRQDRVSCK- 1457 Query: 381 EATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDF-MHRNNKMFMS 439 + L S EVR + +S A I D MHR F Sbjct: 1458 --SLQSGATLLFSSFNEVRNLSEQPVMLNVAWS-----ANDSRITGFDLAMHRQMGYF-- 1508 Query: 440 ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTM 499 S E ++ + ++R L + + ++VDW+ GNV+ S + I C+ Sbjct: 1509 -SAEDEGIVYQVDLQTKVIVRAL--GLPAPTKLSVDWVTGNVYVL----SGAQEIQACSF 1561 Query: 500 SGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWI----DSY-QKYHRIMMANMDGSQVRIL 554 G C R++ K + + L V I +I + Y Q I MA +DGS+ +L Sbjct: 1562 VGRMCGRIVHVKSP-RHVKHLAVDGYHARIFYIVIRTEGYGQTSSEIHMARLDGSRRDML 1620 Query: 555 LDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKE---RRVVI----SNGVHHPYD 607 L +AL D + +YF D + +ER++ K RR I SN + HP Sbjct: 1621 LQRSESFMTALTTDPHQQLLYFVDQHMRTLERISYRLKTGPMRRPEIMLQKSNALMHPSG 1680 Query: 608 MAYFNGFLYWADWGS-ESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPC 666 ++ + + + GS E+++ I+ N I V Q S+PC Sbjct: 1681 LSVYENNAFIVNLGSMEAVQCALYGSRICHKISINVLN--AQDIVVAGRSRQPQKASHPC 1738 Query: 667 LELECPWLCV 676 C LC+ Sbjct: 1739 AHAHCHGLCL 1748
Score = 92.0 bits (227), Expect = 4e-17 Identities = 86/337 (25%), Positives = 120/337 (35%), Gaps = 64/337 (18%) Query: 38 FDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGE 97 F CG+G CI W+CD DC G DE C C +G C+ CDG Sbjct: 1163 FQCGSG--SCIAGSWECDGRIDCSDGSDEHDKCVHRSCPPDMHRCLSGQCLDRSLVCDGH 1220 Query: 98 DDCRDGSDEQHC--------------EYNILKS---------RFDGSNPSAPTTFVGHNG 134 +DC D SDE +C +Y + R +G+ G Sbjct: 1221 NDCGDKSDELNCGTDSSTMNISCAEDQYQCTSNLKICLPSAVRCNGTTECPRGEDEADCG 1280 Query: 135 PECHPPRLRCRSG-QCIQPDLVCDGHQDCSGGDDEVNCT-RRGHENMQSSTDFHDDVHLV 192 C +CRSG +CI+ + CDG +DC G DE++C +GH N + Sbjct: 1281 DVCSIYEFKCRSGRECIRREFRCDGQKDCGDGSDELSCELEKGHHNQSQIQPWSTSSRSC 1340 Query: 193 DPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSG 252 P F +D +C +C++ C C T S SG Sbjct: 1341 RPHLFDCQDGECVDLSRVCNNFPDCTNGHDEGP------------KCATACRSA----SG 1384 Query: 253 QADHMHSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHC---SECARKR- 308 + H C A P A C+ L D + K C EC ++ Sbjct: 1385 RQVCQHKCRAT----------------PAGAVCSCFDGYRL-DADQKSCLDIDECQEQQP 1427 Query: 309 CDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECAT 345 C C NT G +C C + L D ++C+ AT Sbjct: 1428 CAQLCENTLGGYQCQCHADFMLRQDRVSCKSLQSGAT 1464
Score = 77.8 bits (190), Expect = 7e-13 Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 10/141 (7%) Query: 29 NSTCDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGL-C 87 N +C + ++ C + C+P+ +C+ +C +G DE+ C CS C++G C Sbjct: 1240 NISCAE-DQYQCTSNLKICLPSAVRCNGTTECPRGEDEADCGDV--CSIYEFKCRSGREC 1296 Query: 88 VANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSG 147 + EF+CDG+ DC DGSDE CE K + S +T + C P C+ G Sbjct: 1297 IRREFRCDGQKDCGDGSDELSCELE--KGHHNQSQIQPWST----SSRSCRPHLFDCQDG 1350 Query: 148 QCIQPDLVCDGHQDCSGGDDE 168 +C+ VC+ DC+ G DE Sbjct: 1351 ECVDLSRVCNNFPDCTNGHDE 1371
Score = 68.2 bits (165), Expect = 6e-10 Identities = 76/320 (23%), Positives = 104/320 (32%), Gaps = 75/320 (23%) Query: 32 CDQAKEFDCGNGRLRCIPAEWQCDNVADCDKGRDESGC---------SYAHH---CST-S 78 C F C C+ AE C+ + +C G DE C AH CS Sbjct: 129 CRPPHWFPCAQPHGACLAAELMCNGIDNCPGGEDELNCPVRPGFRFGDTAHRMRSCSKYE 188 Query: 79 FMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECH 138 FM ++ C+ +F CDG DC D SDE G + T C Sbjct: 189 FMCQQDRTCIPIDFMCDGRPDCTDKSDE-----------VAGCKQAEIT---------CP 228 Query: 139 PPRLRCRSGQCI-QPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFF 197 C +G+C+ + VCDG DC G DE C ++L +P Sbjct: 229 GEGHLCANGRCLRRKQWVCDGVDDCGDGSDERGC-----------------LNLCEP--- 268 Query: 198 ANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADHM 257 + G +C + + C+ E + + P + Sbjct: 269 -------QKGKFLCRNRETCLTLSEVCDGHSDCSDGSDETDLCHSKPDCDAKKCALGAKC 321 Query: 258 HSCSAAGMYSCGTKGSEIGVCIPMNATCNGIKECPLGDDESKHCSECARKRCDHTCMNTP 317 H A+G KG + C + EC DD C C NT Sbjct: 322 HMMPASGAECFCPKGFRLA---KFEDKCEDVDECKEQDD-----------LCSQGCENTS 367 Query: 318 HGARCICQEGYKLADDGLTC 337 G RC+C GY L D TC Sbjct: 368 GGYRCVCDAGYLLDKDNRTC 387
Score = 52.0 bits (123), Expect = 4e-05 Identities = 45/138 (32%), Positives = 56/138 (40%), Gaps = 14/138 (10%) Query: 40 CGNGRLRCI-PAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKN-GLCVANEFKCDGE 97 C NG RC+ +W CD V DC G DE GC LC+N C+ CDG Sbjct: 234 CANG--RCLRRKQWVCDGVDDCGDGSDERGCLNLCEPQKGKFLCRNRETCLTLSEVCDGH 291 Query: 98 DDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNGPECHPP---RLRCRSGQC----- 149 DC DGSDE ++ A + +G EC P RL +C Sbjct: 292 SDCSDGSDETDLCHSKPDCDAKKCALGAKCHMMPASGAECFCPKGFRLAKFEDKCEDVDE 351 Query: 150 --IQPDLVCDGHQDCSGG 165 Q DL G ++ SGG Sbjct: 352 CKEQDDLCSQGCENTSGG 369
Score = 40.4 bits (93), Expect = 0.13 Identities = 94/477 (19%), Positives = 172/477 (36%), Gaps = 67/477 (14%) Query: 342 ECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 E AT HLC E +G +C C +G L D C LFI LG + ++ Sbjct: 665 ENATCSHLCL-LAEPEIGGHSCACPDGMRLAPDHRRC---MLMEKRQRLFIGLGQVLLEI 720 Query: 402 PLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRV 461 F + + + I + + N + ++ +D+ E + + Sbjct: 721 EHTAF---GAHQVSKSYTLPCLINEMVYNRINGSLIIADNDQR--LILEFQPESHESNVL 775 Query: 462 LRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLV 521 +R N+ VS +A D + N+++ + +S+ T R G+E GL Sbjct: 776 VRSNLGNVSALAFDHLSRNLYWADTERAVIEVLSLQTRHRALI-RFFPGQEVPI---GLT 831 Query: 522 VHPMRGLIIWIDSYQKYHRI--MMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDV 579 V P G + + +++ I + + G QV + D+ + L DY +++ D Sbjct: 832 VMPAEGYLYVVLKAKRHSHIDKIPLSGKGEQVHVFEDDLGDDDIKLVTDYETQTIFWSDS 891 Query: 580 ERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL-----------KVQ 628 + I N + + + PY +A + L+W + G+ + KV Sbjct: 892 DLGRISYSNYRVPHSQ-IFRGKLRRPYSLAMVHHDLFWNELGTPRIYWTHKSNMGPRKVI 950 Query: 629 EMTHHHSSPQVI-HTFNRYPYGIAVNHSLYQTGPPSNPCLELE--CPWLCVIVPKSDFIM 685 ++ ++ + P GI + S G S+PC + C +CV + Sbjct: 951 DIMEKDDPAAIMPYVPVATPNGIPLAAS-SPVGQESHPCQQQNGGCSHICV----GEGPY 1005 Query: 686 TAKCVCPDGYTHSVTEN-SCIPPVTIEDEENLEKLSHIGSAL-MAEYCEAGVACMNGGAC 743 + C+CP G+ + N +C+ + + E H G L M C C++ Sbjct: 1006 HSICLCPAGFVYRDAGNRTCVEAL------DCEFRCHSGECLTMNHRCNGRRDCVDNSDE 1059 Query: 744 RELQNEHGRAHRIVC------------------------DCEGPYDGQYCERLNPEK 776 EH +++C DC D Q+CE+ + K Sbjct: 1060 MNCDEEHRHKPKVLCSPSQFACHSGEQCVDKERRCDNRKDCHDHSDEQHCEKFDKSK 1116
>gi|24641935|ref|NP_511151.2| CG1372-PA [Drosophila melanogaster] gi|22832717|gb|AAF48349.2| CG1372-PA [Drosophila melanogaster] Length = 1937 Score = 184 bits (466), Expect = 7e-45 Identities = 162/663 (24%), Positives = 264/663 (39%), Gaps = 83/663 (12%) Query: 75 CSTSFMLCKNGLCVANEFKCDGEDDCRDGSDEQHCEYNILKSRFDGSNPSAPTTFVGHNG 134 C C++G C+ CDG DC+D SDE C+Y + Sbjct: 90 CDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDYRL--------------------- 128 Query: 135 PECHPPR-LRCRS--GQCIQPDLVCDGHQDCSGGDDEVNCTRRGHENMQSSTDFHDDVHL 191 C PP C G C+ +L+C+G +C GG+DE+NC R F D H Sbjct: 129 --CRPPHWFPCAQPHGACLAAELMCNGIDNCPGGEDELNCPVR------PGFRFGDTAHR 180 Query: 192 VDPTFFANEDNKCRSGYTMCHSGDVCIPXXXXXXXXXXXXXXXXE----KNCQTNAPSEE 247 + C MC CIP E K + P E Sbjct: 181 M---------RSCSKYEFMCQQDRTCIPIDFMCDGRPDCTDKSDEVAGCKQAEITCPGEG 231 Query: 248 EYLS-GQADHMHSCSAAGMYSCGTKGSEIG------------------VCIPMNATCNGI 288 + G+ G+ CG E G C+ ++ C+G Sbjct: 232 HLCANGRCLRRKQWVCDGVDDCGDGSDERGCLNLCEPQKGKFLCRNRETCLTLSEVCDGH 291 Query: 289 KECPLGDDESKHC---SECARKRC--DHTCMNTP-HGARCICQEGYKLADDGLTCEDEDE 342 +C G DE+ C +C K+C C P GA C C +G++LA CED DE Sbjct: 292 SDCSDGSDETDLCHSKPDCDAKKCALGAKCHMMPASGAECFCPKGFRLAKFEDKCEDVDE 351 Query: 343 CATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQMP 402 C LC CE+ G + C C GY L+ D +C+ + E + ++ M Sbjct: 352 CKEQDDLCSQGCENTSGGYRCVCDAGYLLDKDNRTCRAVVYGSKEQQPLLLYTTQMTIMG 411 Query: 403 LADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRVL 462 + + + + + + AG+ + + I + + ++ + + + + + +L Sbjct: 412 M-HLREDNVRNHVYQVAGNLS-KVIGVAYDGSHIYWTNIQNEAESIVKANGDGSNAEILL 469 Query: 463 RENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLVV 522 + ++AVDW+ N++F S + I++C+ G+ C ++ + R L V Sbjct: 470 TSGLDAPEDLAVDWLTQNIYF---SDNIMRHIAVCSNDGLNCAVLV--TQDVHQPRSLAV 524 Query: 523 HPMRGLIIWIDSYQKYHRIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQ 582 P +GL+ W D +K I A+MDGS+ R ++ + +E P+ +A+D + +Y+ D + Sbjct: 525 WPQKGLMFWTDWGEK-PMIGRASMDGSRSRPIVSDNIEWPNGIALDMHQQRIYWVDAKLG 583 Query: 583 LIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESLKVQEMTHHHSSPQVIHT 642 ++ V D RR V+ + HPY +A F LYW+DW ++S V I Sbjct: 584 SVQTVRPDGTGRRTVLDGMLKHPYGLAIFEDQLYWSDWATKS--VHACHKFSGKDHRILA 641 Query: 643 FNRYPYGIAVNHSLYQTGPPSNPCLELECPWLCVIVPKSDFIMTAKCVCPDGYTHSVTEN 702 +R Y + + H Q P C C LC++ I C CPDG + Sbjct: 642 KDRTIYAVHIYHPAKQPNSPHG-CENATCSHLCLLAEPE--IGGHSCACPDGMRLAPDHR 698 Query: 703 SCI 705 C+ Sbjct: 699 RCM 701
Score = 172 bits (436), Expect = 2e-41 Identities = 179/670 (26%), Positives = 262/670 (39%), Gaps = 79/670 (11%) Query: 40 CGNGRLRCIPAEWQCDNVADCDKGRDESGCSYAHHCSTSFMLCKNGLCVANEFKCDGEDD 99 C NG +C+ + CD DC DE C C C +G C+A ++CDG D Sbjct: 1125 CDNG--KCVDSSLVCDGTNDCGDNSDELLCEATSRCEPGMFQCGSGSCIAGSWECDGRID 1182 Query: 100 CRDGSDEQ-HCEYNILKSRFDGSNPSAPTTFVGHNGPECHPPRLRCRSGQCIQPDLVCDG 158 C DGSDE C + C P RC GQC+ LVCDG Sbjct: 1183 CSDGSDEHDKCVHR-----------------------SCPPDMQRCLLGQCLDRSLVCDG 1219 Query: 159 HQDCSGGDDEVNC-TRRGHENMQSSTDFH---DDVHLVDP-TFFANEDNKCRSGYTMCHS 213 H DC DE+NC T N+ + D + ++ + P T N +C G Sbjct: 1220 HNDCGDKSDELNCGTDSSTMNISCAEDQYQCTSNLKICLPSTVRCNGTTECPRGEDEADC 1279 Query: 214 GDVCIPXXXXXXXXXXXXXXXXEKNCQTNAPSEEEYLSGQADH-MHSCSAAGMYSCGTKG 272 GDVC + Q + + LS + + H+ S +S ++ Sbjct: 1280 GDVCSIYEFKCRSGRECIRREFRCDGQKDCGDGSDELSCELEKGHHNQSQIQPWSTSSRS 1339 Query: 273 -------SEIGVCIPMNATCNGIKECPLGDDESKHC-----SECARKRCDHTCMNTPHGA 320 + G C+ ++ CN +C G DE C S R+ C H C TP GA Sbjct: 1340 CRPHLFDCQDGECVDLSRVCNNFPDCTNGHDEGPKCATACRSASGRQVCQHKCRATPAGA 1399 Query: 321 RCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKY 380 C C +GY+L D +C D DEC C CE+ LG + C+C + L D SCK Sbjct: 1400 VCSCFDGYRLDADQKSCLDIDECQEQ-QPCAQLCENTLGGYQCQCHADFMLRQDRVSCK- 1457 Query: 381 EATTTPEGYLFISLGGEVRQMPLADFTDGSNYSAIQKFAGHGTIRSIDF-MHRNNKMFMS 439 + L S EVR + +S A I D MHR F Sbjct: 1458 --SLQSGATLLFSSFNEVRNLSEQPVMLNVAWS-----ANDSRITGFDLAMHRQMGYF-- 1508 Query: 440 ISDEHGDPTGELSVSDNGLMRVLRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTM 499 S E ++ + ++R L + + ++VDW+ GNV+ S + I C+ Sbjct: 1509 -SAEDEGIVYQIDLQTKVIVRAL--GLPAPTKLSVDWVTGNVYVL----SGAQEIQACSF 1561 Query: 500 SGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWI----DSY-QKYHRIMMANMDGSQVRIL 554 G C R++ K + + L V I +I + Y Q I MA +DGS+ +L Sbjct: 1562 VGRMCGRIVHVKSP-RHVKHLAVDGYHARIFYIVIRTEGYGQTSSEIHMARLDGSRRDML 1620 Query: 555 LDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKE---RRVVI----SNGVHHPYD 607 L +AL D + +YF D + +ER++ K RR I SN + HP Sbjct: 1621 LQRSESFMTALTTDPHQQLLYFVDQHMRTLERISYRLKTGPMRRPEIMLQKSNALMHPSG 1680 Query: 608 MAYFNGFLYWADWGS-ESLKVQEMTHHHSSPQVIHTFNRYPYGIAVNHSLYQTGPPSNPC 666 ++ + + + GS E+++ I+ N I V Q S+PC Sbjct: 1681 LSVYENNAFIVNLGSVEAVQCALYGSRICHKISINVLN--AQDIVVAGRSRQPQKASHPC 1738 Query: 667 LELECPWLCV 676 C LC+ Sbjct: 1739 AHAHCHGLCL 1748
Score = 42.7 bits (99), Expect = 0.024 Identities = 95/477 (19%), Positives = 173/477 (36%), Gaps = 67/477 (14%) Query: 342 ECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYEATTTPEGYLFISLGGEVRQM 401 E AT HLC E +G +C C +G L D C LFI LG + ++ Sbjct: 665 ENATCSHLCL-LAEPEIGGHSCACPDGMRLAPDHRRC---MLMEKRQRLFIGLGQVLLEI 720 Query: 402 PLADFTDGSNYSAIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRV 461 F + + + I + + N + ++ +D+ E + + Sbjct: 721 EHTAF---GRHQVSKSYTLPCLINEMVYNRINGSLIIADNDQR--LILEFQPESHESNVL 775 Query: 462 LRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGISICTMSGMFCRRVIEGKEQGQSYRGLV 521 +R N+ VS +A D + N+++ + +S+ T R G+E GL Sbjct: 776 VRSNLGNVSALAFDHLSRNLYWADTERAVIEVLSLQTRHRALI-RFFPGQEVPI---GLT 831 Query: 522 VHPMRGLIIWIDSYQKYHRI--MMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDV 579 V P G + + +++ I + + G QV + D+ + L DY +++ D Sbjct: 832 VMPAEGYLYVVLKAKRHSHIDKIPLSGKGEQVHVFEDDLGDDDIKLVTDYETQTIFWSDS 891 Query: 580 ERQLIERVNIDTKERRVVISNGVHHPYDMAYFNGFLYWADWGSESL-----------KVQ 628 + I N + + + PY +A + L+W + G+ + KV Sbjct: 892 DLGRISYSNYRVPHSQ-IFRGKLRRPYSLAMVHHDLFWNELGTPRIYWTHKSNMGPRKVI 950 Query: 629 EMTHHHSSPQVI-HTFNRYPYGIAVNHSLYQTGPPSNPCLELE--CPWLCVIVPKSDFIM 685 ++ ++ + P GI + S G S+PC + C +CV + Sbjct: 951 DIMEKDDPAAIMPYVPVATPNGIPLAAS-SPVGQESHPCQQQNGGCSHICV----GEGPY 1005 Query: 686 TAKCVCPDGYTHSVTEN-SCIPPVTIEDEENLEKLSHIGSAL-MAEYCEAGVACMNGGAC 743 + C+CP G+ + N +C+ + + E H G L M C C++ Sbjct: 1006 HSICLCPAGFVYRDAGNRTCVEAL------DCEFRCHSGECLTMNHRCNGRRDCVDNSDE 1059 Query: 744 RELQNEHGRAHRIVC------------------------DCEGPYDGQYCERLNPEK 776 EH R +++C DC D Q+CE+ + K Sbjct: 1060 MNCDEEHRRKPKVLCSPNQFACHSGEQCVDKERRCDNRKDCHDHSDEQHCEKFDKSK 1116
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Nov 27, 2002 12:59 AM Number of letters in database: 396,357,784 Number of sequences in database: 1,244,887 Lambda K H 0.320 0.135 0.435 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 774,510,497 Number of Sequences: 1244887 Number of extensions: 34392790 Number of successful extensions: 89844 Number of sequences better than 10.0: 1588 Number of HSP's better than 10.0 without gapping: 873 Number of HSP's successfully gapped in prelim test: 730 Number of HSP's that attempted gapping in prelim test: 65724 Number of HSP's gapped (non-prelim): 12300 length of query: 925 length of database: 396,357,784 effective HSP length: 132 effective length of query: 793 effective length of database: 232,032,700 effective search space: 184001931100 effective search space used: 184001931100 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 77 (34.3 bits)
