Blast Family of Programs
The BLAST family of programs allows all combinations of DNA or protein query sequences with searches
against DNA or protein databases:
     blastp    compares an amino acid query  sequence  against  a
               protein sequence database.
     blastn    compares a nucleotide  query  sequence  against  a
               nucleotide sequence database.
     blastx    compares  the  six-frame  conceptual   translation
               products  of  a  nucleotide  query  sequence (both
               strands) against a protein sequence database.
     tblastn   compares  a  protein  query  sequence  against   a
               nucleotide     sequence    database    dynamically
               translated  in  all  six  reading   frames   (both
               strands).
     tblastx   compares the six-frame translations of  a  nucleo-
               tide query sequence against the six-frame transla-
               tions of a nucleotide sequence database.
The default matrix for all protein-protein comparisons is BLOSUM62.