BLAST Alignments for blat_ecoli.sw
beta-lactamase (EC 3.5.2.6) precursor - Escherichia coli
plasmids
Length = 286
Score = 547 bits (1393), Expect = e-155
Identities = 272/286 (95%), Positives = 272/286 (95%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
PAAMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
Sbjct: 181 PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
beta-lactamase (EC 3.5.2.6) - synthetic
Length = 286
Score = 547 bits (1393), Expect = e-155
Identities = 272/286 (95%), Positives = 272/286 (95%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
PAAMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
Sbjct: 181 PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
beta-lactamase (EC 3.5.2.6) precursor - synthetic
Length = 286
Score = 545 bits (1388), Expect = e-155
Identities = 270/286 (94%), Positives = 271/286 (94%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSR+DAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
P AMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
Sbjct: 181 PVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
beta-lactamase (EC 3.5.2.6) - phage phi-X174
Length = 286
Score = 545 bits (1388), Expect = e-155
Identities = 270/286 (94%), Positives = 271/286 (94%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSR+DAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
P AMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
Sbjct: 181 PVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
extended spectrum beta-lactamase CAZ-7 - Klebsiella
pneumoniae
Length = 286
Score = 541 bits (1380), Expect = e-154
Identities = 269/286 (94%), Positives = 271/286 (94%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAED+LGARVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLV+YSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLD WEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
PAAMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
Sbjct: 181 PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
beta-lactamase (EC 3.5.2.6) TEM-3 - Klebsiella
pneumoniae plasmid pCFF04
Length = 286
Score = 541 bits (1379), Expect = e-154
Identities = 269/286 (94%), Positives = 271/286 (94%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAED+LGARVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLV+YSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
PAAMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGA ERGS
Sbjct: 181 PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGS 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
extended spectrum beta-lactamase CAZ-2 - Klebsiella
pneumoniae
Length = 286
Score = 539 bits (1373), Expect = e-153
Identities = 268/286 (93%), Positives = 270/286 (93%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAED+LGARVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLV+YSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLD WEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
PAAMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGA ERGS
Sbjct: 181 PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGS 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
beta-lactamase (EC 3.5.2.6) TEM-1 - Klebsiella
pneumoniae transposon Tn1331
Length = 286
Score = 538 bits (1371), Expect = e-153
Identities = 267/286 (93%), Positives = 270/286 (94%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAED+LGARVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLV+YSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLD WEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
PAAMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSG G+RGS
Sbjct: 181 PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGS 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
Bla protein - Salmonella typhimurium plasmid NTP16
Length = 286
Score = 536 bits (1367), Expect = e-152
Identities = 268/286 (93%), Positives = 268/286 (93%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP 60
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLG RVGYIELDLNSGKILESFRP
Sbjct: 1 MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGDRVGYIELDLNSGKILESFRP 60
Query: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL 120
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH SQNDLVEYSPVTEKHLTDGMTVREL
Sbjct: 61 EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHISQNDLVEYSPVTEKHLTDGMTVREL 120
Query: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
Sbjct: 121 CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM 180
Query: 181 PAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS 240
PAAMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERG
Sbjct: 181 PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGY 240
Query: 241 RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
GIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 241 SGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
beta-lactamase (EC 3.5.2.6) SHV-2 precursor -
Salmonella typhimurium plasmid pHT1
Length = 286
Score = 362 bits (920), Expect = e-100
Identities = 177/284 (62%), Positives = 217/284 (76%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++ R+ +I A L V A P+ L ++K +E QL RVG IE+DL SG+ L ++R +E
Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKQSESQLSGRVGMIEMDLASGRTLTAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPMMSTFKV+LCGAVL+RVDAG EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+
Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAITMSDN+AANLLL T+GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA
Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
+MA S++QL+ WM D+VAGPL+RS LPAGWFIADK+GA ERG+RG
Sbjct: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARG 240
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
I+A LGP+ K RIVVIY + A+M ERN+QIA IGA+LI+HW
Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHW 284
beta-lactamase (EC 3.5.2.6) - Klebsiella pneumoniae
Length = 286
Score = 362 bits (920), Expect = e-100
Identities = 177/284 (62%), Positives = 217/284 (76%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++ R+ +I A L V A P+ L ++K +E QL RVG IE+DL SG+ L ++R +E
Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKQSESQLSGRVGMIEMDLASGRTLTAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPMMSTFKV+LCGAVL+RVDAG EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+
Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAITMSDN+AANLLL T+GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA
Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
+MA S++QL+ WM D+VAGPL+RS LPAGWFIADK+GA ERG+RG
Sbjct: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARG 240
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
I+A LGP+ K RIVVIY + A+M ERN+QIA IGA+LI+HW
Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHW 284
beta-lactamase (EC 3.5.2.6) SHV-2 - Klebsiella ozaenae
plasmid pBP60
Length = 286
Score = 361 bits (916), Expect = 2e-99
Identities = 177/284 (62%), Positives = 217/284 (76%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++ R+ +I A L V A P+ L ++K +E QL RVG IE+DL SG+ L ++R +E
Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPMMSTFKV+LCGAVL+RVDAG EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+
Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAITMSDN+AANLLL T+GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA
Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
+MA S++QL+ WM D+VAGPL+RS LPAGWFIADK+GA ERG+RG
Sbjct: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARG 240
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
I+A LGP+ K RIVVIY + A+M ERN+QIA IGA+LI+HW
Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHW 284
beta-lactamase (EC 3.5.2.6) 2A precursor - Klebsiella
pneumoniae plasmid BWH77
Length = 286
Score = 361 bits (916), Expect = 2e-99
Identities = 177/284 (62%), Positives = 217/284 (76%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++ R+ +I A L V A P+ L ++K +E QL RVG IE+DL SG+ L ++R +E
Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPMMSTFKV+LCGAVL+RVDAG EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+
Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAITMSDN+AANLLL T+GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA
Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
+MA S++QL+ WM D+VAGPL+RS LPAGWFIADK+GA ERG+RG
Sbjct: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARG 240
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
I+A LGP+ K RIVVIY + A+M ERN+QIA IGA+LI+HW
Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHW 284
beta-lactamase (EC 3.5.2.6) SHV-3, cefotaxime
resistance-conferring - Klebsiella pneumoniae
Length = 286
Score = 360 bits (913), Expect = 4e-99
Identities = 177/284 (62%), Positives = 216/284 (75%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++ R+ +I A L V A P+ L ++K +E QL RVG IE+DL SG+ L ++R +E
Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPMMSTFKV+LCGAVL+RVDAG EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+
Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAITMSDN+AANLLL T+GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA
Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
+MA S+ QL+ WM D+VAGPL+RS LPAGWFIADK+GA ERG+RG
Sbjct: 181 SMAATLRKLLTSQRLSARSQLQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARG 240
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
I+A LGP+ K RIVVIY + A+M ERN+QIA IGA+LI+HW
Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHW 284
beta-lactamase (EC 3.5.2.6) precursor - Klebsiella
pneumoniae plasmids
Length = 286
Score = 359 bits (912), Expect = 5e-99
Identities = 176/284 (61%), Positives = 217/284 (75%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++ R+ +I A L V A P+ L ++K +E QL RVG IE+DL SG+ L ++R +E
Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPMMSTFKV+LCGAVL+RVDAG EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+
Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAITMSDN+AANLLL T+GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA
Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
+MA S++QL+ WM D+VAGPL+RS LPAGWFIADK+GA +RG+RG
Sbjct: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARG 240
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
I+A LGP+ K RIVVIY + A+M ERN+QIA IGA+LI+HW
Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHW 284
beta-lactamase (EC 3.5.2.6) shv-1 precursor -
Klebsiella sp. plasmid R974
Length = 287
Score = 354 bits (898), Expect = 2e-97
Identities = 176/285 (61%), Positives = 216/285 (75%), Gaps = 1/285 (0%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++ R+ +I A L V A P+ L ++K +E QL RVG IE+DL SG+ L ++R +E
Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPMMSTFKV+LCGAVL+RVDAG EQL R+IHY Q DLV+YSPV+EKHL D MTV ELC+
Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADAMTVGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAITMSDN+AANLLL T+GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA
Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180
Query: 183 AMAXXXXXXXXXXXXXXA-SRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSR 241
+MA A S++QL+ WM D+VAGPL+RS LPAGWFIADK+GAGERG+R
Sbjct: 181 SMAATLRNVGLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGAR 240
Query: 242 GIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
GI+A LGP+ K RIVVIY + A+M ERN+QIA IG +L +HW
Sbjct: 241 GIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGKALYEHW 285
beta-lactamase (EC 3.5.2.6) class A - Escherichia coli
plasmid p453
Length = 265
Score = 353 bits (897), Expect = 3e-97
Identities = 172/262 (65%), Positives = 207/262 (78%)
Query: 25 PETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDA 84
P+ L ++K +E QL RVG IE+DL SG+ L ++R +ERFPMMSTFKV+LCGAVL+RVDA
Sbjct: 2 PQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDA 61
Query: 85 GQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPK 144
G EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+AAITMSDN+AANLLLT +GGP
Sbjct: 62 GDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLTAVGGPA 121
Query: 145 ELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQ 204
LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA+MA S++Q
Sbjct: 122 GLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQ 181
Query: 205 LIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGS 264
L+ WM D+VAGPL+RS LPAGWFIADK+GAGERG+RGI+A LGP+ K RIVVIY +
Sbjct: 182 LLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDT 241
Query: 265 QATMDERNRQIAEIGASLIKHW 286
A+M ERN+QIA IGA+LI+HW
Sbjct: 242 PASMAERNQQIAGIGAALIEHW 263
beta-lactamase (EC 3.5.2.6) SHV-2 - Escherichia coli
Length = 265
Score = 351 bits (891), Expect = 1e-96
Identities = 171/262 (65%), Positives = 206/262 (78%)
Query: 25 PETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDA 84
P+ L ++K +E QL RVG IE+DL SG+ L ++R +ERFPMMSTFKV+LCGAVL+RVDA
Sbjct: 2 PQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDA 61
Query: 85 GQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPK 144
G EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+AAITMSDN+AANLLLT +GGP
Sbjct: 62 GDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLTAVGGPA 121
Query: 145 ELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQ 204
LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA+MA S++Q
Sbjct: 122 GLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQ 181
Query: 205 LIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGS 264
L+ WM D+VAGPL+RS LPAGWFIADK+GA ERG+RGI+A LGP+ K RIVVIY +
Sbjct: 182 LLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRDT 241
Query: 265 QATMDERNRQIAEIGASLIKHW 286
A+M ERN+QIA IGA+LI+HW
Sbjct: 242 PASMAERNQQIAGIGAALIEHW 263
beta-lactamase (EC 3.5.2.6) CAZ-5 - Klebsiella
pneumoniae (strain 210-2)
Length = 265
Score = 348 bits (884), Expect = 1e-95
Identities = 170/262 (64%), Positives = 205/262 (77%)
Query: 25 PETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDA 84
P+ L ++K +E QL RVG IE+DL SG+ L ++R +ERFPMMSTFKV+LCGAVL+RVDA
Sbjct: 2 PQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDA 61
Query: 85 GQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPK 144
G EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+AAITMSDN+AANLLL T+GGP
Sbjct: 62 GDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPA 121
Query: 145 ELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQ 204
LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA+MA S+ Q
Sbjct: 122 GLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQLQ 181
Query: 205 LIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGS 264
L+ WM D+VAGPL+RS LPAGWFIADK+GA +RG+RGI+A LGP+ K RIVVIY +
Sbjct: 182 LLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRDT 241
Query: 265 QATMDERNRQIAEIGASLIKHW 286
A+M ERN+QIA IGA+LI+HW
Sbjct: 242 PASMAERNQQIAGIGAALIEHW 263
beta-lactamase (EC 3.5.2.6) precursor - Klebsiella
pneumoniae
Length = 279
Score = 346 bits (878), Expect = 5e-95
Identities = 168/277 (60%), Positives = 209/277 (74%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++ R+ +I A L V+A P+ L ++K +E QL RVG +E+DL +G+ L ++R +E
Sbjct: 1 MRYVRLCVISLLATLPLVVYAGPQPLEQIKQSESQLSGRVGMVEMDLANGRTLAAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPM+STFKVLLCGAVL+RVDAG QL RRIHY Q DLV+YSPV+EKHL DGMT+ ELC+
Sbjct: 61 RFPMVSTFKVLLCGAVLARVDAGLFQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAIT+SDN+A NLLL T+GGP LTAFL +GD+VTRLDRWE LNEA+P D RDTT PA
Sbjct: 121 AAITLSDNSAGNLLLATVGGPAGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPA 180
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
+MA S+QQL+ WM D+VAGPL+R+ LP GWFIADK+GAGERG+RG
Sbjct: 181 SMAATLRKLLTAQHLSARSQQQLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARG 240
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIG 279
I+A LGPDGKP RIVVIY + A+M ERN+ IA IG
Sbjct: 241 IVALLGPDGKPERIVVIYLRDTPASMAERNQHIAGIG 277
beta-lactamase (EC 3.5.2.6) (OHIO-1) - Enterobacter
cloacae plasmid pDS075
Length = 286
Score = 337 bits (854), Expect = 3e-92
Identities = 168/284 (59%), Positives = 208/284 (73%)
Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62
+++FR+ +I A L V A P+ L ++K +E QL VG IE+DL L ++R +E
Sbjct: 1 MRYFRLCIISLLATLPLRVHAGPQPLEQIKLSESQLSGSVGMIEMDLARPGTLTAWRADE 60
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RFPMMSTFKV+LCGA L+RVDAG EQL R+IHY + DLV+YSPV+EKHL DGMTV ELC+
Sbjct: 61 RFPMMSTFKVVLCGAGLARVDAGDEQLERKIHYRRQDLVDYSPVSEKHLADGMTVGELCA 120
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
AAITMSDN+AANLLL +GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT
Sbjct: 121 AAITMSDNSAANLLLPAVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTAR 180
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
+MA S++QL+ WM D+VAG L+RS LPAGWFIADK+GAGERG+RG
Sbjct: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGRLIRSVLPAGWFIADKTGAGERGARG 240
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
I+A LGP+ K RIVVIY + A+M ERN+QIA I +LI+HW
Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIAGALIEHW 284
beta-lactamase (EC 3.5.2.6) precursor - Proteus
mirabilis
Length = 298
Score = 243 bits (615), Expect = 3e-64
Identities = 126/280 (45%), Positives = 170/280 (60%), Gaps = 2/280 (0%)
Query: 6 FRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFP 65
F V + L A L V +AE +LGAR+G DL +GK E + ERFP
Sbjct: 11 FSVVITFLCLTLSLNANATDSVLEAVTNAETELGARIGLAAHDLETGKRWEH-KSNERFP 69
Query: 66 MMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHL-TDGMTVRELCSAA 124
+ STFK L C VL RVD G+E++ R + +S+++LV YSPVTEKH+ GM++ ELC A
Sbjct: 70 LSSTFKTLACANVLQRVDLGKERIDRVVRFSESNLVTYSPVTEKHVGKKGMSLAELCQAT 129
Query: 125 ITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAM 184
++ SDN+AAN +L IGGPK LT FL ++GD TRLDRWEPELNEA+P D+RDTT P AM
Sbjct: 130 LSTSDNSAANFILQAIGGPKALTKFLRSIGDDTTRLDRWEPELNEAVPGDKRDTTTPIAM 189
Query: 185 AXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGII 244
SRQQL W++ ++V L R +P+ W +AD++GAG GSR I
Sbjct: 190 VTTLEKLLIDETLSIKSRQQLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAIT 249
Query: 245 AALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIK 284
A + P + + +Y T + A+ +ERN IA+IG + K
Sbjct: 250 AVMWPPNRKPIVAALYITETDASFEERNAVIAKIGEQIAK 289
beta-lactamase (EC 3.5.2.6) PSE-4 precursor -
Staphylococcus aureus
Length = 304
Score = 199 bits (501), Expect = 8e-51
Identities = 116/287 (40%), Positives = 162/287 (56%), Gaps = 9/287 (3%)
Query: 4 QHFRVALIPFFAAFCL----PVFAHPETLVKV----KDAEDQLGARVGYIELDLNSGKIL 55
Q++ V + F AF L VFA +V K E L AR+G LD +G+
Sbjct: 10 QNYGVTYMKFLLAFSLLIPSVVFASSSKFQQVEQDVKAIEVSLSARIGVSVLDTQNGEYW 69
Query: 56 ESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGM 115
+ + +RFP+ STFK + C +L + G+ + + DLV YSPV EK + +
Sbjct: 70 D-YNGNQRFPLTSTFKTIACAKLLYDAEQGKVNPNSTVEIKKADLVTYSPVIEKQVGQAI 128
Query: 116 TVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDE 175
T+ + C A +T SDNTAAN++L+ +GGPK +T FL +GD TRLDR EP+LNE D
Sbjct: 129 TLDDACFATMTTSDNTAANIILSAVGGPKGVTDFLRQIGDKETRLDRIEPDLNEGKLGDL 188
Query: 176 RDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGA 235
RDTT P A+A ++++L WM ++V G LLRS LPAGW IAD+SGA
Sbjct: 189 RDTTTPKAIASTLNKFLFGSALSEMNQKKLESWMVNNQVTGNLLRSVLPAGWNIADRSGA 248
Query: 236 GERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASL 282
G G+R I A + + + IV IY +QA+M+ERN I +IG S+
Sbjct: 249 GGFGARSITAVVWSEHQAPIIVSIYLAQTQASMEERNDAIVKIGHSI 295
beta-lactamase (EC 3.5.2.6) PSE-1 - Pseudomonas
aeruginosa plasmid RPL11 transposon Tn1403
Length = 304
Score = 198 bits (497), Expect = 2e-50
Identities = 116/287 (40%), Positives = 161/287 (55%), Gaps = 9/287 (3%)
Query: 4 QHFRVALIPFFAAFCL----PVFAHPETLVKV----KDAEDQLGARVGYIELDLNSGKIL 55
Q++ V + F AF L VFA +V K E L AR+G LD +G+
Sbjct: 10 QNYGVTYMKFLLAFSLLIPSVVFASSSKFQQVEQDVKAIEVSLSARIGVSVLDTQNGEYW 69
Query: 56 ESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGM 115
+ + +RFP+ STFK + C +L + G+ + + DLV YSPV EK + +
Sbjct: 70 D-YNGNQRFPLTSTFKTIACAKLLYDAEQGKVNPNSTVEIKKADLVTYSPVIEKQVGQAI 128
Query: 116 TVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDE 175
T+ + C A +T SDNTAAN++L+ +GGPK +T FL +GD TRLDR EP+LNE D
Sbjct: 129 TLDDACFATMTTSDNTAANIILSAVGGPKGVTDFLRQIGDKETRLDRIEPDLNEGKLGDL 188
Query: 176 RDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGA 235
RDTT P A+A ++++L WM ++V G LLRS LPAGW IAD+SGA
Sbjct: 189 RDTTTPKAIASTLNKFLFGSALSEMNQKKLESWMVNNQVTGNLLRSVLPAGWNIADRSGA 248
Query: 236 GERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASL 282
G G+R I A + + + IV IY +QA+M ERN I +IG S+
Sbjct: 249 GGFGARSITAVVWSEHQAPIIVSIYLAQTQASMAERNDAIVKIGHSI 295
beta-lactamase (EC 3.5.2.6) CARB-3 - Pseudomonas
aeruginosa plasmid pMON44
Length = 288
Score = 195 bits (491), Expect = 1e-49
Identities = 107/252 (42%), Positives = 148/252 (58%), Gaps = 1/252 (0%)
Query: 31 VKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLG 90
VK E L AR+G LD +G+ + + +RFP+ STFK + C +L + G+
Sbjct: 29 VKAIEVSLSARIGVSVLDTQNGEYWD-YNGNQRFPLTSTFKTIACAKLLYDAEQGKVNPN 87
Query: 91 RRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFL 150
+ + DLV YSPV EK + +T+ + C A +T SDNTAAN++L+ +GGPK +T FL
Sbjct: 88 STVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGPKGVTDFL 147
Query: 151 HNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWME 210
+GD TRLDR EP+LNE D RDTT P A+A ++++L WM
Sbjct: 148 RQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKLLFGSALSEMNQKKLESWMV 207
Query: 211 ADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDE 270
++V G LLRS LPAGW IAD+SGAG G+R I A + + + IV IY +QA+M E
Sbjct: 208 NNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQTQASMAE 267
Query: 271 RNRQIAEIGASL 282
RN I +IG S+
Sbjct: 268 RNDAIVKIGHSI 279
beta-lactamase (EC 3.5.2.6) precursor - Proteus
mirabilis plasmid pCS229
Length = 288
Score = 193 bits (485), Expect = 6e-49
Identities = 106/252 (42%), Positives = 147/252 (58%), Gaps = 1/252 (0%)
Query: 31 VKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLG 90
VK E L AR+G LD +G+ + + +RFP+ STFK + C +L + G+
Sbjct: 29 VKAIEVSLSARIGVSVLDTQNGEYWD-YNGNQRFPLTSTFKTIACAKLLYDAEQGKVNPN 87
Query: 91 RRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFL 150
+ + DLV YSPV EK + +T+ + C A +T SDNTAAN++L+ +GG K +T FL
Sbjct: 88 STVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGSKGVTDFL 147
Query: 151 HNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWME 210
+GD TRLDR EP+LNE D RDTT P A+A ++++L WM
Sbjct: 148 RQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNKKKLESWMV 207
Query: 211 ADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDE 270
++V G LLRS LPAGW IAD+SGAG G+R I A + + + IV IY +QA+M E
Sbjct: 208 NNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQTQASMAE 267
Query: 271 RNRQIAEIGASL 282
RN I +IG S+
Sbjct: 268 RNDAIVKIGRSI 279
beta-lactamase (EC 3.5.2.6) - Proteus mirabilis
Length = 276
Score = 189 bits (475), Expect = 9e-48
Identities = 106/252 (42%), Positives = 147/252 (58%), Gaps = 2/252 (0%)
Query: 31 VKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLG 90
VK E L AR+G LD +G+ + + +RFP+ STFK + C +L + G+
Sbjct: 18 VKAIEVSLSARIGVSVLDTQNGEYWD-YNGNQRFPLTSTFKTIACAKLLYDAEQGKVNPN 76
Query: 91 RRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFL 150
+ + DLV YSPV EK + +T+ + C A +T SDNTAAN++L+ +GG K +T FL
Sbjct: 77 STVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGSKGVTDFL 136
Query: 151 HNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWME 210
+GD TRLDR EP+LNE D RDTT P A+A ++++L WM
Sbjct: 137 RQIGDK-TRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNKKKLESWMV 195
Query: 211 ADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDE 270
++V G LLRS LPAGW IAD+SGAG G+R I A + + + IV IY +QA+M E
Sbjct: 196 NNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQTQASMAE 255
Query: 271 RNRQIAEIGASL 282
RN I +IG S+
Sbjct: 256 RNDAIVKIGRSI 267
beta-lactamase (EC 3.5.2.6) precursor - Rhodobacter
capsulatus
Length = 293
Score = 189 bits (474), Expect = 1e-47
Identities = 106/264 (40%), Positives = 155/264 (58%), Gaps = 5/264 (1%)
Query: 20 PVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVL 79
PV A ET+ ++ E+QLGARVG ++ +G S R +E F M ST KV +CGA+L
Sbjct: 30 PVEALSETVARI---EEQLGARVGLSLMETGTGWSW-SHREDELFLMNSTVKVPVCGAIL 85
Query: 80 SRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTT 139
+R DAG+ L + + DLV Y+PVTE + MT+ ELC AAI MSDN AAN+L+
Sbjct: 86 ARWDAGRLSLSDALPVRKADLVPYAPVTETRVGGNMTLDELCLAAIDMSDNVAANILIGH 145
Query: 140 IGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXX 199
+GGP+ +T F ++GD +RLDR EP+LN+ DERDTT PAAM+
Sbjct: 146 LGGPEAVTQFFRSVGDPTSRLDRIEPKLNDFASGDERDTTSPAAMSETLRALLLGDVLSP 205
Query: 200 ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVI 259
+R +L +WM V G LLR+ W I DKSG+G +R ++A + P+G I +
Sbjct: 206 EARGKLAEWMRHGGVTGALLRAEAEDAWLILDKSGSGSH-TRNLVAVIQPEGGAPWIATM 264
Query: 260 YTTGSQATMDERNRQIAEIGASLI 283
+ + + A + RN + ++G +++
Sbjct: 265 FISDTDAEFEVRNEALKDLGRAVV 288
beta-lactamase (EC 3.5.2.6) precursor - Klebsiella
oxytoca (strain SL781 and others)
Length = 291
Score = 186 bits (468), Expect = 6e-47
Identities = 97/247 (39%), Positives = 143/247 (57%), Gaps = 1/247 (0%)
Query: 30 KVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQL 89
K+ D E + G R+G + L + +R +ERF M ST KV+ AVL + ++ E +
Sbjct: 36 KLADLEKRSGGRLG-VALINTADDSQTLYRGDERFAMCSTGKVMAAAAVLKQSESNPEVV 94
Query: 90 GRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAF 149
+R+ ++DLV +SP+TEKHL GMT+ EL +AA+ SDNTA N +++ +GGP+++TAF
Sbjct: 95 NKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGPEKVTAF 154
Query: 150 LHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWM 209
++GD RLDR EP LN AIP D+RDTT P AMA R QL+ W+
Sbjct: 155 AQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRAQLVTWL 214
Query: 210 EADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMD 269
+ + G +R+ LPA W + DK+GAG+ G+ IA + P+ ++V Y T Q
Sbjct: 215 KGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQPQQDAK 274
Query: 270 ERNRQIA 276
R +A
Sbjct: 275 SRKEVLA 281
beta-lactamase (EC 3.5.2.6) - Yersinia enterocolitica
Length = 294
Score = 186 bits (468), Expect = 6e-47
Identities = 102/267 (38%), Positives = 150/267 (55%), Gaps = 6/267 (2%)
Query: 16 AFCLPVFAH--PETLVK-VKDAEDQLGARVGYIELDLNSG-KILESFRPEERFPMMSTFK 71
+F LP +A+ P ++ K + + E R+G ++ +G KIL +R +RFP STFK
Sbjct: 21 SFALPAWANALPASVDKQLAELERNANGRLGVAMINTGNGTKIL--YRAAQRFPFCSTFK 78
Query: 72 VLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNT 131
+L AVL + + L + I+Y ++DL+ Y+P+T K+L GMTV ELC+A I SDNT
Sbjct: 79 FMLAAAVLDQSQSQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNT 138
Query: 132 AANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXX 191
AANLL+ +GG + F ++GD + RLDRWEP+LN A PND RDTT PAAMA
Sbjct: 139 AANLLIKELGGLAAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKL 198
Query: 192 XXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDG 251
A R QL W++ + +R+ P W + DK+G+G+ G+ IA L P
Sbjct: 199 VLGDALRPAQRSQLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTK 258
Query: 252 KPSRIVVIYTTGSQATMDERNRQIAEI 278
++V+Y T + R +A +
Sbjct: 259 GAPIVLVVYFTQREKDAKPRRDVLASV 285
beta-lactamase (EC 3.5.2.6) penP - Bacillus subtilis
Length = 306
Score = 185 bits (466), Expect = 1e-46
Identities = 102/248 (41%), Positives = 137/248 (55%), Gaps = 3/248 (1%)
Query: 30 KVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQL 89
K E + AR+G +D+ S K + ++RP ERF ST+KVL AVL + E+L
Sbjct: 52 KFVQLEKKFDARLGVYAIDIGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNSI--EKL 108
Query: 90 GRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAF 149
IHYS++DLV YSP+TEKHL GM+++E+ AAI SDNTA N+LL +GGPK
Sbjct: 109 NEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGPKGFEKS 168
Query: 150 LHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWM 209
L +GDHVT+ R+E +LN AIP D RDT+ A+A R L DWM
Sbjct: 169 LKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRMILTDWM 228
Query: 210 EADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMD 269
+ L+R+ P GW + DKSGAG G+R IA + P + +V I + +
Sbjct: 229 RGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNRFTKDAN 288
Query: 270 ERNRQIAE 277
N IAE
Sbjct: 289 YDNALIAE 296
beta-lactamase (EC 3.5.2.6) I precursor - Streptomyces
lactamdurans
Length = 302
Score = 185 bits (465), Expect = 1e-46
Identities = 96/243 (39%), Positives = 139/243 (56%), Gaps = 3/243 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
+ Q AR+G +D SG+ + +FR +ERF STFK L AVL +QL + +
Sbjct: 53 QTQYDARLGLYAVDTGSGESV-AFRADERFAFASTFKALAAAAVLDSTTP--QQLDQVVR 109
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
YS+++L+E SP+T+ H+ GMT+RELC AA+ SDNTA NLLL +GGP+ L A L +G
Sbjct: 110 YSKDELLENSPITKDHVATGMTLRELCDAAVRFSDNTAGNLLLKHVGGPQGLDAALTAVG 169
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D VT DRWEPELN A+P D RDT+ P A+A R L DW+ +
Sbjct: 170 DEVTSADRWEPELNSAVPGDVRDTSTPRALAHDLRQFVLGDALAEDDRALLTDWLRRNTT 229
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
G ++R+ +PA W + DK+G+G G R IA L P + ++ + T+ + +
Sbjct: 230 GGTVIRAGVPADWVVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAVMTSREEPRAKRADAL 289
Query: 275 IAE 277
+A+
Sbjct: 290 LAD 292
beta-lactamase (EC 3.5.2.6), cefotaxime-hydrolyzing -
Klebsiella oxytoca (strain D483)
Length = 263
Score = 185 bits (464), Expect = 2e-46
Identities = 98/246 (39%), Positives = 146/246 (58%), Gaps = 5/246 (2%)
Query: 30 KVKDAEDQLGARVGYIELDL-NSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQ 88
K+ D E + G R+G ++ ++ +IL +R +ERF M ST KV+ AVL + ++ +E
Sbjct: 8 KLTDLEKRSGGRLGVALINTADNSQIL--YRGDERFAMCSTSKVMAAAAVLKQSESNKEV 65
Query: 89 LGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTA 148
+ +R+ + DLV +SP+TEKHL GMT+ EL +A + SDNTA NL++ +GGP+++TA
Sbjct: 66 VNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGPEKVTA 125
Query: 149 FLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDW 208
F ++GD RLDR EP LN AIP DERDT+ P AMA R QL+ W
Sbjct: 126 FARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRAQLVTW 185
Query: 209 MEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATM 268
++ + G +R LP W + DK+GAG+ G+ IA + P+ ++V Y T Q
Sbjct: 186 LKGNTTGGQSIRVGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFT--QPQQ 243
Query: 269 DERNRQ 274
D +NR+
Sbjct: 244 DAKNRK 249
penicillinase - Bacillus amyloliquefaciens
Length = 306
Score = 183 bits (459), Expect = 7e-46
Identities = 102/248 (41%), Positives = 136/248 (54%), Gaps = 3/248 (1%)
Query: 30 KVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQL 89
K E + AR+G +D S K + ++RP ERF ST+KVL AVL + E+L
Sbjct: 52 KFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKQKPI--EKL 108
Query: 90 GRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAF 149
I Y++ DLV YSP+TEKHL GM+++E+ AAI SDNTA N+LL +GGPK
Sbjct: 109 NDVIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGPKGFEKS 168
Query: 150 LHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWM 209
L +GDHVT+ DR+E +LN AIP D RDT+ A+A R L DWM
Sbjct: 169 LKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRTILTDWM 228
Query: 210 EADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMD 269
+ L+R+ PAGW + DKSGAG G+R IA + P + ++ I T +
Sbjct: 229 RGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILTKRFTKDAE 288
Query: 270 ERNRQIAE 277
N IAE
Sbjct: 289 YDNALIAE 296
bla protein - Pseudomonas aeruginosa (fragment)
Length = 105
Score = 180 bits (453), Expect = 3e-45
Identities = 91/105 (86%), Positives = 91/105 (86%)
Query: 182 AAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSR 241
AAMA ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSR
Sbjct: 1 AAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSR 60
Query: 242 GIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286
GIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Sbjct: 61 GIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 105
beta-lactamase (EC 3.5.2.6) precursor - Streptomyces
fradiae
Length = 306
Score = 180 bits (452), Expect = 4e-45
Identities = 97/242 (40%), Positives = 136/242 (56%), Gaps = 5/242 (2%)
Query: 40 ARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQND 99
AR+G D +G+ + ++R +ERFP+ S FK + AVL +D E L RR+HY+ +
Sbjct: 55 ARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLDRDGEVLARRVHYTADY 113
Query: 100 LVE--YSPVT--EKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGD 155
+ YSPVT +++ +GMTV ELC A +T SDNTAANLLL +GGP +T F ++GD
Sbjct: 114 VKRSGYSPVTGLPENVANGMTVAELCEATLTRSDNTAANLLLRDLGGPTAVTRFCRSVGD 173
Query: 156 HVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVA 215
HVTRLDRWEPELN A P DTT P A+ R++L WM ++ +
Sbjct: 174 HVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRERLTRWMLDNRTS 233
Query: 216 GPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQI 275
R LPA W +ADK+G G+ G+ P G+P ++ + TT + N +
Sbjct: 234 DERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTRFTPDAEADNVLV 293
Query: 276 AE 277
AE
Sbjct: 294 AE 295
beta-lactamase (EC 3.5.2.6), cefotaxime-hydrolyzing -
Escherichia coli
Length = 291
Score = 178 bits (446), Expect = 2e-44
Identities = 94/252 (37%), Positives = 141/252 (55%), Gaps = 4/252 (1%)
Query: 35 EDQLGARVGYIELDL-NSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRI 93
E G R+G ++ ++ +IL +R +ERF M ST KV+ AVL + ++ + L +R+
Sbjct: 41 EKSSGGRLGVALINTADNSQIL--YRADERFAMCSTSKVMAAAAVLKQSESNKHLLNQRV 98
Query: 94 HYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNM 153
++DLV Y+P+ EKH+ MT+ EL +AA+ SDNTA N L+ +GGP ++TAF ++
Sbjct: 99 EIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGPDKVTAFARSL 158
Query: 154 GDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADK 213
GD RLDR EP LN AIP D RDTT P AMA R QL+ W++ +
Sbjct: 159 GDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRAQLVTWLKGNT 218
Query: 214 VAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNR 273
+R+ LP W + DK+G+G+ G+ IA + P+ ++V Y T + ER R
Sbjct: 219 TGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQPEQKA-ERRR 277
Query: 274 QIAEIGASLIKH 285
I A ++ H
Sbjct: 278 DILAAAAKIVTH 289
beta-lactamase (EC 3.5.2.6) precursor, indubible (clone
p-beta-C-1) - Streptomyces cacaoi
Length = 314
Score = 177 bits (445), Expect = 3e-44
Identities = 96/226 (42%), Positives = 134/226 (58%), Gaps = 5/226 (2%)
Query: 30 KVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQL 89
++K ED+ R+G +D SG+ + ++R ERFP STFK L CGAVL + ++
Sbjct: 59 ELKALEDEFDVRLGVYAVDTGSGREV-AYRDGERFPYNSTFKALECGAVLDKHT--DREM 115
Query: 90 GRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAF 149
R + YS++DLV+ SPVTEKH+ DGMT+ LC AA+ SDNTAANLL T+GGPK L
Sbjct: 116 DRVVKYSEDDLVDNSPVTEKHVEDGMTLTALCDAAVRYSDNTAANLLFETVGGPKGLDKT 175
Query: 150 LHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWM 209
L +GDHVTR++R EP L+ P +RDT+ P A A R+QL W+
Sbjct: 176 LEGLGDHVTRMERVEPFLSRWEPGSKRDTSTPRAFAKDLRAYVLGDVLAEGDRKQLTTWL 235
Query: 210 EADKVAGPLLRSALPAGWFIADKSGAGE-RGSRGIIAAL-GPDGKP 253
+ L+R+ + GW + DK+G G G+R +A + PDG+P
Sbjct: 236 RNNTTGDGLIRAGVRQGWVVGDKTGTGSYYGARNDMAVVWRPDGRP 281
beta-lactamase (EC 3.5.2.6) ROB-1 precursor -
Haemophilus influenzae plasmid R-Rob
Length = 305
Score = 177 bits (445), Expect = 3e-44
Identities = 102/253 (40%), Positives = 145/253 (56%), Gaps = 8/253 (3%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E Q AR+G D +G L S+R +ERF STFK LL GAVL + ++ L R I
Sbjct: 54 EQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP--EKDLNRTIS 110
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
YSQ DLV YSP T+K++ GMT+ +LC AA+ SDN+A NLLL +GG ++ L +G
Sbjct: 111 YSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGVEQYQRILRQLG 170
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D+VT +R EP+LN+A PND RDT+ P MA + + L +W++ +
Sbjct: 171 DNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKTILWNWLDNNAT 230
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALG-PDGKPSRIVVIYTTGSQATMDER-N 272
PL+R+A P W + DKSGAG+ G R IA + P+ KP +V+ +Q T + + N
Sbjct: 231 GNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKP---IVMAIMSTQFTEEAKFN 287
Query: 273 RQIAEIGASLIKH 285
++ E A + H
Sbjct: 288 NKLVEDAAKQVFH 300
beta-lactamase (EC 3.5.2.6) ROB-1 - Actinobacillus
pleuropneumoniae
Length = 305
Score = 177 bits (445), Expect = 3e-44
Identities = 102/253 (40%), Positives = 145/253 (56%), Gaps = 8/253 (3%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E Q AR+G D +G L S+R +ERF STFK LL GAVL + ++ L R I
Sbjct: 54 EQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP--EKDLNRTIS 110
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
YSQ DLV YSP T+K++ GMT+ +LC AA+ SDN+A NLLL +GG ++ L +G
Sbjct: 111 YSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGVEQYQRILRQLG 170
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D+VT +R EP+LN+A PND RDT+ P MA + + L +W++ +
Sbjct: 171 DNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKTILWNWLDNNAT 230
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALG-PDGKPSRIVVIYTTGSQATMDER-N 272
PL+R+A P W + DKSGAG+ G R IA + P+ KP +V+ +Q T + + N
Sbjct: 231 GNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKP---IVMAIMSTQFTEEAKFN 287
Query: 273 RQIAEIGASLIKH 285
++ E A + H
Sbjct: 288 NKLVEDAAKQVFH 300
beta-lactamase (EC 3.5.2.6) ROB1 - Pasteurella
haemolytica
Length = 305
Score = 177 bits (445), Expect = 3e-44
Identities = 102/253 (40%), Positives = 145/253 (56%), Gaps = 8/253 (3%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E Q AR+G D +G L S+R +ERF STFK LL GAVL + ++ L R I
Sbjct: 54 EQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP--EKDLNRTIS 110
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
YSQ DLV YSP T+K++ GMT+ +LC AA+ SDN+A NLLL +GG ++ L +G
Sbjct: 111 YSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGVEQYQRILRQLG 170
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D+VT +R EP+LN+A PND RDT+ P MA + + L +W++ +
Sbjct: 171 DNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKTILWNWLDNNAT 230
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALG-PDGKPSRIVVIYTTGSQATMDER-N 272
PL+R+A P W + DKSGAG+ G R IA + P+ KP +V+ +Q T + + N
Sbjct: 231 GNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKP---IVMAIMSTQFTEEAKFN 287
Query: 273 RQIAEIGASLIKH 285
++ E A + H
Sbjct: 288 NKLVEDAAKQVFH 300
beta-lactamase (EC 3.5.2.6) - Klebsiella oxytoca
Length = 263
Score = 175 bits (440), Expect = 1e-43
Identities = 93/248 (37%), Positives = 140/248 (55%), Gaps = 3/248 (1%)
Query: 30 KVKDAEDQLGARVGYIELDL-NSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQ 88
K+ + E Q G R+G ++ ++ +IL +R +ERF M ST KV+ AVL + ++
Sbjct: 8 KLAELERQSGGRLGVALINTADNSQIL--YRADERFAMCSTSKVMAVAAVLKKSESEPNL 65
Query: 89 LGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTA 148
L +R+ ++DLV Y+P+ EKH+ M++ EL +AA+ SDN A N L++ +GGP +TA
Sbjct: 66 LNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGPASVTA 125
Query: 149 FLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDW 208
F +GD RLDR EP LN AIP D RDTT P AMA + R QL+ W
Sbjct: 126 FARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTW 185
Query: 209 MEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATM 268
M+ + +++ LPA W + DK+G+G+ G+ IA + P + I+V Y T Q
Sbjct: 186 MKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQPQPKA 245
Query: 269 DERNRQIA 276
+ R +A
Sbjct: 246 ESRRDVLA 253
beta-lactamase (EC 3.5.2.6) precursor - Bacillus cereus
Length = 306
Score = 173 bits (435), Expect = 4e-43
Identities = 94/250 (37%), Positives = 137/250 (54%), Gaps = 3/250 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E + AR+G +D + + + S+RP ERF ST+K L G +L + + L I
Sbjct: 57 EKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNSI--DSLNEVIT 113
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
Y++ DLV+YSPVTEKH+ GM + E+ AA+ SDNTA N+L IGGPK L +MG
Sbjct: 114 YTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGPKGYEKALRHMG 173
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D +T +R+E ELNEAIP D RDT+ A+A R+ L +WM+ +
Sbjct: 174 DRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRKILTEWMKGNAT 233
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
L+R+ +P W + DKSGAG G+R IA + P + I+ I ++ + N+
Sbjct: 234 GDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSKDEKEAIYDNQL 293
Query: 275 IAEIGASLIK 284
IAE ++K
Sbjct: 294 IAEATKVIVK 303
beta-lactamase (EC 3.5.2.6) class A precursor -
Citrobacter diversus
Length = 294
Score = 173 bits (435), Expect = 4e-43
Identities = 105/272 (38%), Positives = 154/272 (56%), Gaps = 11/272 (4%)
Query: 9 ALIPFFAAFCLPVFAHPE---TLVKVKDA--EDQLGARVGYIELDL-NSGKILESFRPEE 62
A++ FF A P+ A + T V+ K A E Q G R+G ++ + +IL +R +E
Sbjct: 14 AVLAFFTASS-PLLARTQGEPTQVQQKLAALEKQSGGRLGVALINTADRSQIL--YRGDE 70
Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122
RF M ST K ++ AVL + + + L +++ + DL ++PVTEK++ MT+ EL +
Sbjct: 71 RFAMCSTSKTMVAAAVLKQSETQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSA 130
Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182
A + SDNTA N LL +GG +TAF ++GD RLDR EPELN AIP DERDTT P
Sbjct: 131 ATLQYSDNTAMNKLLEHLGGTSNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTCPL 190
Query: 183 AMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242
AMA A R QL++W++ + G +R+ LP GW + DK+GAG+ G+
Sbjct: 191 AMAKSLHKLTLGDALAGAQRAQLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGAGDYGTTN 250
Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
IA + P+ + I+V Y T Q D + R+
Sbjct: 251 DIAVIWPEDRAPLILVTYFT--QPQQDAKGRK 280
beta-lactamase (EC 3.5.2.6) precursor - Bacillus
licheniformis
Length = 307
Score = 171 bits (428), Expect = 3e-42
Identities = 90/250 (36%), Positives = 141/250 (56%), Gaps = 3/250 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E+Q A++G LD + + + ++RP+ERF ST K L G +L + E L +RI
Sbjct: 54 EEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKSI--EDLNQRIT 110
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
Y+++DLV Y+P+TEKH+ GMT++EL A++ SDN A NL+L IGGP+ L L +G
Sbjct: 111 YTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGPESLKKELRKIG 170
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D VT +R+EPELNE P + +DT+ A+ R+ LIDWM+ +
Sbjct: 171 DEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRELLIDWMKRNTT 230
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
L+R+ +P GW +ADK+GA G+R IA + P ++ + ++ + ++
Sbjct: 231 GDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSRDKKDAKYDDKL 290
Query: 275 IAEIGASLIK 284
IAE ++K
Sbjct: 291 IAEATKVVMK 300
beta-lactamase (EC 3.5.2.6) precursor (clone pDML51) -
Streptomyces cacaoi
Length = 325
Score = 171 bits (428), Expect = 3e-42
Identities = 94/258 (36%), Positives = 137/258 (52%), Gaps = 14/258 (5%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRV---------DAG 85
E + A G +D G+ + + R +ERF STFK L GA+L++V A
Sbjct: 61 EKKFDAHPGVYAIDTRDGQEI-THRADERFAYGSTFKALQAGAILAQVLRDGREVRRGAE 119
Query: 86 QEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKE 145
+ + + +HY Q+ ++ SPVTEKH+ DGM++RELC A + SDNTAANLL +GG +
Sbjct: 120 ADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVAYSDNTAANLLFDQLGGRRG 179
Query: 146 LTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXA----S 201
T L +GDH T +DR+E EL A+P D RDT+ P A A A
Sbjct: 180 STRVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDGEKAALAPND 239
Query: 202 RQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYT 261
R+QL DWM + L+R+ +P W + DKSG + G+R IA + P G+ +V + +
Sbjct: 240 REQLNDWMSGSRTGDALIRAGVPKDWKVEDKSGQVKYGTRNDIAVVRPPGRAPIVVSVMS 299
Query: 262 TGSQATMDERNRQIAEIG 279
G + + +AE G
Sbjct: 300 HGDTQDAEPHDELVAEAG 317
beta-lactamase (EC 3.5.2.6) I precursor - Bacillus
cereus (strain 5/B)
Length = 306
Score = 170 bits (427), Expect = 4e-42
Identities = 96/249 (38%), Positives = 135/249 (53%), Gaps = 3/249 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E + AR+G +D + + + ++RP ERF ST+K L G +L + ++L I
Sbjct: 57 EKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNST--KKLDEVIT 113
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
Y++ DLV+YSPVTEKH+ GMT+ E+ AA+ SDNTA N+L IGGPK L MG
Sbjct: 114 YTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRKMG 173
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D VT DR+E ELNEAIP D RDT+ A+A R L +WM+ +
Sbjct: 174 DRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRNILTEWMKGNAT 233
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
L+R+ +P W ADKSGAG G+R IA + P + I+ I ++ + N+
Sbjct: 234 GDKLIRAGVPTDWVDADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSKDEKEATYDNQL 293
Query: 275 IAEIGASLI 283
I E +I
Sbjct: 294 IKEAAEVVI 302
beta-lactamase (EC 3.5.2.6) precursor - Bacillus
thuringiensis
Length = 309
Score = 170 bits (426), Expect = 5e-42
Identities = 94/250 (37%), Positives = 134/250 (53%), Gaps = 3/250 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E + ARVG +D + + + S+R ERF ST+K L G +L + + L I
Sbjct: 60 EKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNSI--DTLNEVIT 116
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
+++ DLV+YSPVTEKH+ GM + E+ AA+ SDNTA N+L IGGPK L MG
Sbjct: 117 FTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGPKGYEKALRKMG 176
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D VT DR+E ELNEAIP D RDT+ +A R+ L +WM+ +
Sbjct: 177 DRVTMSDRFETELNEAIPGDIRDTSTAKRIATNLKAFTVGNALPAEKRKILTEWMKGNAT 236
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
L+R+ +P W + DKSGAG G+R IA + P + I+ I ++ + N+
Sbjct: 237 GDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKEASYDNQL 296
Query: 275 IAEIGASLIK 284
IAE ++K
Sbjct: 297 IAEATEVIVK 306
beta-lactamase (EC 3.5.2.6) class A precursor -
Mycobacterium fortuitum (strain FC1)
Length = 294
Score = 170 bits (426), Expect = 5e-42
Identities = 105/250 (42%), Positives = 141/250 (56%), Gaps = 11/250 (4%)
Query: 20 PVFAHP--ETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGA 77
P FA P + L +++ ++ L +G +L SG+ + + R +E F M STFK
Sbjct: 29 PAFAAPIDDQLAELERRDNVL---IGLYAANLQSGRRI-THRLDEMFAMCSTFKGYAAAR 84
Query: 78 VLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLL 137
VL + G+ L R+ + LV SPVTE MT+ ELC AA+ SDNTAANLLL
Sbjct: 85 VLQMAEHGEISLDNRVFVDADALVPNSPVTEARAGAEMTLAELCQAALQRSDNTAANLLL 144
Query: 138 TTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXX 197
TIGGP +TAF ++GD TRLDRWE ELN AIP D RDT+ AA+A
Sbjct: 145 KTIGGPAAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTAAALAVGYRAILAGDAL 204
Query: 198 XXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIA-ALGPDGKPSRI 256
R L DWM A++ + +R+ LP GW ADK+G+G+ GS A GPDG+ R+
Sbjct: 205 SPPQRGLLEDWMRANQTSS--MRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQ--RL 260
Query: 257 VVIYTTGSQA 266
+++ T SQA
Sbjct: 261 LLVMMTRSQA 270
beta-lactamase (EC 3.5.2.6) - Streptomyces cellulosae
Length = 311
Score = 169 bits (425), Expect = 6e-42
Identities = 98/234 (41%), Positives = 130/234 (54%), Gaps = 5/234 (2%)
Query: 24 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVD 83
+P + +++ E + AR+G L+L +G L R E FPM S FK L AVL +D
Sbjct: 43 NPAAVRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD 101
Query: 84 AGQEQLGRRIHYSQNDLVE--YSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIG 141
QL R I Y++ D+ + ++PVT+ H+ GMT+R+LC A I SDN AANLLL +G
Sbjct: 102 HDGSQLARVIRYTEADVTKSGHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELG 161
Query: 142 GPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXAS 201
GP +T F ++GD VTRLDRWEPELN P+ DTT P A+A
Sbjct: 162 GPTAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPD 221
Query: 202 RQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGER-GSRGIIA-ALGPDGKP 253
R L DW+ + R+ LP GW +ADKSG G+ G+R A A PDG P
Sbjct: 222 RALLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDTYGTRNEAAIAWTPDGAP 275
beta-lactamase (EC 3.5.2.6) I precursor - Bacillus
cereus
Length = 306
Score = 169 bits (424), Expect = 8e-42
Identities = 93/250 (37%), Positives = 138/250 (55%), Gaps = 4/250 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E + AR+G +D + + + S+RP ERF ST+K L G +L + + L I
Sbjct: 59 EKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNSI--DSLNEVIT 115
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
Y++ DLV+YSPVTEKH+ GM + E+ AA+ SDNTA N+L IGGPK L +MG
Sbjct: 116 YTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGPKGYEKALRHMG 175
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D +T +R+E ELNEAIP D RDT+ A+A R+ L +WM+ +
Sbjct: 176 DRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRKILTEWMKGNAT 235
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
L+R+ +P W + DKSGAG G+R IA + P + I+V+ ++ + ++
Sbjct: 236 GDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNS-APIIVLISSKDEKEAIYNDQL 294
Query: 275 IAEIGASLIK 284
IAE ++K
Sbjct: 295 IAEATKVIVK 304
beta-lactamase (EC 3.5.2.6) precursor - Streptomyces
lavendulae
Length = 305
Score = 169 bits (424), Expect = 8e-42
Identities = 100/271 (36%), Positives = 142/271 (51%), Gaps = 6/271 (2%)
Query: 16 AFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLC 75
AF P +P+ L +++ E + AR+G D +G+ + R EERFPM S FK L
Sbjct: 32 AFAAPR-GNPDVLRQLRALEQEHSARLGVYARDTATGRTV-LHRAEERFPMCSVFKTLAV 89
Query: 76 GAVLSRVDAGQEQLGRRIHYSQNDLVE--YSPVT--EKHLTDGMTVRELCSAAITMSDNT 131
AVL +D E L R+ Y++ ++ + + PVT ++L GMTV LC+AAI SDN
Sbjct: 90 AAVLRDLDRDGEFLATRLFYTEQEVKDSGFGPVTGLPENLAAGMTVERLCAAAICQSDNA 149
Query: 132 AANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXX 191
AANLLL +GGP+ +T F ++GD TRLDRWEPELN A P DTT P A+
Sbjct: 150 AANLLLRELGGPEAVTRFCRSVGDRTTRLDRWEPELNSAEPGRLTDTTTPRAIGATYGEL 209
Query: 192 XXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDG 251
R++L W+ A+ + R LPA W + DK+G G G+ P
Sbjct: 210 VLGDALAPRDRERLTGWLLANTTSTERFRKGLPADWTLGDKTGGGAYGTNNDAGVTWPPH 269
Query: 252 KPSRIVVIYTTGSQATMDERNRQIAEIGASL 282
+P ++V+ TT + N +A+ A L
Sbjct: 270 RPPVVMVVLTTHDRPDAVADNPLVAKTAALL 300
beta-lactamase (EC 3.5.2.6) precursor - Proteus
vulgaris
Length = 300
Score = 169 bits (424), Expect = 8e-42
Identities = 90/228 (39%), Positives = 127/228 (55%)
Query: 57 SFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMT 116
++R EERF M ST KV+ AVL + L + I ++DLV YSP+TEKHLT GMT
Sbjct: 64 TYRGEERFAMASTSKVMAVAAVLKASEKQAGLLDKNITIKKSDLVAYSPITEKHLTTGMT 123
Query: 117 VRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDER 176
+ EL +A + SDNTA N +L +GGP ++T F ++ D RLDR EPELN AI D R
Sbjct: 124 LAELSAATLQYSDNTAMNKILDYLGGPAKVTQFARSINDVTYRLDRKEPELNTAIHGDPR 183
Query: 177 DTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAG 236
DTT P AMA + RQQL+ W++ + +++ LP W + DK+G+G
Sbjct: 184 DTTSPIAMAKSLQALTLGDALGQSQRQQLVTWLKGNTTGDNSIKAGLPKHWVVGDKTGSG 243
Query: 237 ERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIK 284
+ G+ IA + P+ I+V+Y T + R IA+ + K
Sbjct: 244 DYGTTNDIAVIWPENHAPLILVVYFTQQEQNAKYRKDIIAKAAEIVTK 291
beta-lactamase (EC 3.5.2.6) - Bacillus mycoides
Length = 306
Score = 168 bits (422), Expect = 1e-41
Identities = 93/250 (37%), Positives = 135/250 (53%), Gaps = 3/250 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E + AR+G +D + + + S+R ERF ST+K L G +L + + L I
Sbjct: 57 EKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNSI--DTLNEVIK 113
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
+++ DLV+YSPVTEKH+ GM + E+ AA+ SDNTA N+L IGGPK L +G
Sbjct: 114 FTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGPKGYEKALRQIG 173
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D VT DR+E ELNEAIP D RDT+ A+A R+ L +WM+ +
Sbjct: 174 DRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRKILTEWMKGNAT 233
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
L+R+ +P W + DKSGAG G+R IA + P + I+ I ++ + N+
Sbjct: 234 GDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKEATYDNQL 293
Query: 275 IAEIGASLIK 284
IAE ++K
Sbjct: 294 IAEAPEVIVK 303
beta-lactamase (EC 3.5.2.6) precursor - Bacillus sp.
(strain 170)
Length = 310
Score = 166 bits (415), Expect = 1e-40
Identities = 91/243 (37%), Positives = 137/243 (55%), Gaps = 3/243 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E + A++G LD ++ + + ++R +ERF ST K L GAVL + E L +RI
Sbjct: 57 EKEYDAKLGIYALDTSANQTV-TYRSDERFAYASTHKALAVGAVLQKKSI--EDLEQRIK 113
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
Y+ DLV Y+P+TEK++ GMT++EL A+I SDNTA NL+LT +GGP + + +G
Sbjct: 114 YTSKDLVNYNPITEKYIDTGMTLKELMDASIRYSDNTAQNLILTQLGGPSGIQKIMREIG 173
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D VT +R+EPELNE P D RDT+ P A+A +R LID M+
Sbjct: 174 DTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVENRNFLIDLMKRTTT 233
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
L+R+ +P W + DK+G+G G+R IA + P K I+ I + ++ ++
Sbjct: 234 GDNLIRAGVPGEWEVPDKTGSGSYGTRNDIAFIWPPNKKPFILAILSNQAKEDAKYDDKL 293
Query: 275 IAE 277
IA+
Sbjct: 294 IAD 296
beta-lactamase (EC 3.5.2.6) precursor - Streptomyces
aureofaciens
Length = 311
Score = 165 bits (414), Expect = 1e-40
Identities = 94/238 (39%), Positives = 132/238 (54%), Gaps = 6/238 (2%)
Query: 30 KVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQL 89
+++ E Q AR+G LD +G S+R ERFPM S FK L AVL VDA +E L
Sbjct: 50 RLRALEKQYAARLGVFALDTGTGAG-RSYRAGERFPMCSVFKALAAAAVLRDVDARREFL 108
Query: 90 GRRIHYSQNDLVE--YSPVTEK--HLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKE 145
+RIHY++ + + Y PVT K ++ GMT ELC+AA++ SDN A NLLL + GP
Sbjct: 109 TKRIHYTEKFVKDAGYIPVTGKPENIAGGMTGAELCAAAVSESDNGAGNLLLRELDGPTG 168
Query: 146 LTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQL 205
+T F ++GD TRLDRWEP LN A P+ DTT P A+ R++L
Sbjct: 169 ITRFCRSLGDTTTRLDRWEPALNSAEPDRVTDTTSPGAIGRTFGRLIVGSALRAGDRKRL 228
Query: 206 IDWMEADKVAGPLLRSALPAGWFIADKSGAGER-GSRGIIAALGPDGKPSRIVVIYTT 262
W+ A+ P R+ LP W +ADK+G GE+ G + + P G+ ++ + +T
Sbjct: 229 TGWLVANTTNRPTFRAGLPDDWVLADKTGGGEQYGVANDVGVVQPPGRAPLVLSVLST 286
beta-lactamase (EC 3.5.2.6) III precursor - Bacillus
cereus
Length = 316
Score = 164 bits (410), Expect = 4e-40
Identities = 87/243 (35%), Positives = 135/243 (54%), Gaps = 3/243 (1%)
Query: 35 EDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIH 94
E + A++G LD ++ + + ++ ++RF ST K L GA+L + E L RI
Sbjct: 63 EKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNSI--EALDERIT 119
Query: 95 YSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMG 154
Y++ DL Y+P+TEKH+ GMT++EL A++ SD+TA NL+L +GGP L MG
Sbjct: 120 YTRKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGPSAFEKILREMG 179
Query: 155 DHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKV 214
D VT +R+EPELNE P + DT+ P A+A R+ L+DWM+ +
Sbjct: 180 DTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRELLVDWMKRNTT 239
Query: 215 AGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
L+R+ +P GW +ADK+GAG G+R IA + P K ++ I + + + +
Sbjct: 240 GDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNHDKEDAEYDDTL 299
Query: 275 IAE 277
IA+
Sbjct: 300 IAD 302
beta-lactamase (EC 3.5.2.6) - Enterobacter cloacae
Length = 292
Score = 164 bits (410), Expect = 4e-40
Identities = 89/281 (31%), Positives = 153/281 (53%), Gaps = 5/281 (1%)
Query: 1 MSIQHFRVALIPFFAAFCLPVFAHPET--LVKVKDAEDQLGARVGYIELDLNSGKILESF 58
++++ R+A++ + F+ T + ++K+ E R+G LD SGK S+
Sbjct: 3 LNVKQSRIAILFSSCLISISFFSQANTKGIDEIKNLETDFNGRIGVYALDTGSGKSF-SY 61
Query: 59 RPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVR 118
R ERFP+ S+FK L AVL + L + ++Y+ L +SP+T K+ +GM++
Sbjct: 62 RANERFPLCSSFKGFLAAAVLKGSQDNRLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLG 121
Query: 119 ELCSAAITMSDNTAANLLLTT-IGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERD 177
++ +AA+ SDN A N++L IGGP+ +T F+ ++GD RLDRWE +LN AIP DERD
Sbjct: 122 DMAAAALQYSDNGATNIILERYIGGPEGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERD 181
Query: 178 TTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGA-G 236
T+ PAA+A ++ W++ + +R+++P+ W + DK+G+ G
Sbjct: 182 TSTPAAVAKSLKTLALGNILSEHEKETYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCG 241
Query: 237 ERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAE 277
G+ A + P + I+ +YTT ++ ++ IAE
Sbjct: 242 AYGTANDYAVVWPKNRAPLIISVYTTKNEKEAKHEDKVIAE 282
beta-lactamase (EC 3.5.2.6) BPL-1 - Serratia marcescens
Length = 294
Score = 163 bits (408), Expect = 6e-40
Identities = 93/280 (33%), Positives = 146/280 (51%), Gaps = 8/280 (2%)
Query: 5 HFRVALIPFFAAFCLPVF-AHPE----TLVKVKDAEDQLGARVGYIELDLNSGKILESFR 59
+F+ A F L F AH ++K E+ R+G +D SG +R
Sbjct: 6 NFKTASFLFSVCLALSAFNAHANKSDAAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYR 64
Query: 60 PEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRE 119
+ERFP+ S+FK L AVL RV + + +++ Y DL +SP+T K+ GMT+ +
Sbjct: 65 SDERFPLCSSFKGFLAAAVLERVQQKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGD 124
Query: 120 LCSAAITMSDNTAANLLLTT-IGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDT 178
+ SAA+ SDN A N+++ +GGP+ +T F+ ++GD+ RLDRWE ELN AIP D+RDT
Sbjct: 125 MASAALQYSDNGATNIIMERFLGGPEGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDT 184
Query: 179 TMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGA-GE 237
+ P A+A + +W++ + +R+++PA W + DK+G+ G
Sbjct: 185 STPKAVANSLNKLALGNVLNAKVKAIYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGA 244
Query: 238 RGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAE 277
G+ A + P + IV IYTT ++ IAE
Sbjct: 245 IGTANDYAVIWPKNRAPLIVSIYTTRKSKDDKHSDKTIAE 284
beta-lactamase - Proteus vulgaris
Length = 271
Score = 162 bits (407), Expect = 8e-40
Identities = 85/218 (38%), Positives = 124/218 (55%), Gaps = 2/218 (0%)
Query: 57 SFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMT 116
++R EERF M ST KV+ A+L + L + I +++DLV YSP+TEKHL GM+
Sbjct: 35 TYRGEERFAMASTSKVMAVAAILKESEKQAGLLDKNIIITKSDLVAYSPITEKHLATGMS 94
Query: 117 VRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDER 176
+ +L +A + SDNTA N +L +GGP ++T F ++ D RLDR EPELN AI D R
Sbjct: 95 LAQLSAATLQYSDNTAMNKILDYLGGPSKVTQFARSINDVTYRLDRKEPELNTAIHGDPR 154
Query: 177 DTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAG 236
DTT P AMA + RQQL+ W++ + +++ LP W + DK+G+G
Sbjct: 155 DTTSPIAMAKSLQALTLGDALGQSQRQQLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSG 214
Query: 237 ERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
+ G+ IA + P I+V+Y T Q D + R+
Sbjct: 215 DYGTTNDIAVIWPKNHAPLILVVYFT--QQEQDAKYRK 250
beta-lactamase - Proteus vulgaris
Length = 300
Score = 162 bits (407), Expect = 8e-40
Identities = 86/218 (39%), Positives = 123/218 (55%), Gaps = 2/218 (0%)
Query: 57 SFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMT 116
++R EERF M ST KV+ AVL + L + I ++DLV YSP+TEKHL GM+
Sbjct: 64 TYRGEERFAMASTSKVMAVAAVLKESEKQAGLLDKNITIKKSDLVAYSPITEKHLVTGMS 123
Query: 117 VRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDER 176
+ +L +A + SDNTA N +L +GGP ++T F ++ D RLDR EPELN AI D R
Sbjct: 124 LAQLSAATLQYSDNTAMNKILDYLGGPAKVTQFARSINDVTYRLDRKEPELNTAIHGDPR 183
Query: 177 DTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAG 236
DTT P AMA + RQQL+ W++ + +++ LP W + DK+G+G
Sbjct: 184 DTTSPIAMAKSLQALTLGDALGQSQRQQLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSG 243
Query: 237 ERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQ 274
+ G+ IA + P I+V+Y T Q D + R+
Sbjct: 244 DYGTTNDIAVIWPKNHAPLILVVYFT--QQEQDAKYRK 279
beta-lactamase (EC 3.5.2.6) precursor - Streptomyces
albus
Length = 314
Score = 161 bits (402), Expect = 3e-39
Identities = 96/248 (38%), Positives = 133/248 (52%), Gaps = 14/248 (5%)
Query: 31 VKDAEDQL-------GARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVD 83
V DAE +L GAR+G D SG+ + ++R +E FPM S FK L AVL +D
Sbjct: 46 VSDAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD 104
Query: 84 AGQEQLGRRIHYSQNDLVEYS---PVTEK--HLTDG-MTVRELCSAAITMSDNTAANLLL 137
E L RRI Y+Q+D+ + P T K +L + +TV ELC +IT SDN AANL+L
Sbjct: 105 RNGEFLSRRILYTQDDVEQADGAGPETGKPQNLANAQLTVEELCEVSITASDNCAANLML 164
Query: 138 TTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXX 197
+GGP +T F+ ++GD VTRLDRWEPELN A P DTT P A+
Sbjct: 165 RELGGPAAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDAL 224
Query: 198 XXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIV 257
R+ L W+ A+ +G R+ LP W + DK+GAG G+ P G+ ++
Sbjct: 225 NPRDRRLLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVL 284
Query: 258 VIYTTGSQ 265
+ T ++
Sbjct: 285 TVLTAKTE 292
beta-lactamase (EC 3.5.2.6) precursor - Streptomyces
badius
Length = 313
Score = 157 bits (393), Expect = 4e-38
Identities = 89/254 (35%), Positives = 134/254 (52%), Gaps = 5/254 (1%)
Query: 32 KDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGR 91
K E + AR+G +D +G+ + + RF STFK L VLS + L +
Sbjct: 58 KKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYSL--DGLDK 114
Query: 92 RIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTT-IGGPKELTAFL 150
R+ Y++ DLV +SPVTEKH+ GMT++ELC A++ SDNTAANLL GPK L A L
Sbjct: 115 RVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDPRAAGPKGLDASL 174
Query: 151 HNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWME 210
+GD +TR+DR EPEL+ +P ++RDT+ P A+A R QL W+
Sbjct: 175 EKLGDDITRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERAQLTTWLR 234
Query: 211 ADKVAGPLLRSALPAGWFIADKSGAGE-RGSRGIIAALGPDGKPSRIVVIYTTGSQATMD 269
+ ++R+ +P W + DK+G G G+R IA + P ++ I + +
Sbjct: 235 TNTTGDAVIRAGVPENWVVGDKTGTGSYYGARNDIAVVWPPDSAPIVIAILSHRGTKDAE 294
Query: 270 ERNRQIAEIGASLI 283
+ IAE + ++
Sbjct: 295 PDDELIAEAASVVV 308
beta-lactamase (EC 3.5.2.6) precursor - Actinomadura
sp. (strain R39)
Length = 304
Score = 144 bits (359), Expect = 4e-34
Identities = 84/243 (34%), Positives = 124/243 (50%), Gaps = 5/243 (2%)
Query: 35 EDQLGARVGYIELDLNSGKILESF-RPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRI 93
E + AR+G +D +G+ E F R +ERF ST K VL + E+L +
Sbjct: 54 ESEFDARLGVYAVDTGTGE--EVFHRADERFGYASTHKAFTAALVLGQNTP--EELEEVV 109
Query: 94 HYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNM 153
Y++ DLV+YSP+TE+H+ GMT+ E+ AA+ SDNTAANLL +GGP+ + +
Sbjct: 110 TYTEEDLVDYSPITEQHVDTGMTLLEVADAAVRHSDNTAANLLFEELGGPEGFEEDMREL 169
Query: 154 GDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADK 213
GD V DR E ELNE P + RDT+ P AMA R L + + +
Sbjct: 170 GDDVISADRIETELNEVPPGETRDTSTPRAMAGSLEAFVLGDVLEEGPRDVLTEMLLNNT 229
Query: 214 VAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNR 273
L+R+ +P W + DK+G G GSR IA + P ++ + +T Q + N
Sbjct: 230 TGDELIRAGVPEDWRVGDKTGGGSHGSRNDIAVVWPPEDDPIVIAVMSTREQEDAEFDNA 289
Query: 274 QIA 276
++
Sbjct: 290 LVS 292
probable blaC - Mycobacterium tuberculosis (strain
H37RV)
Length = 307
Score = 143 bits (356), Expect = 8e-34
Identities = 88/232 (37%), Positives = 120/232 (50%), Gaps = 8/232 (3%)
Query: 33 DAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRR 92
+ E + AR+G + +E +R +ERF STFK L AVL + L +
Sbjct: 50 ELERRYDARLGVYVPATGTTAAIE-YRADERFAFCSTFKAPLVAAVLHQNPL--THLDKL 106
Query: 93 IHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP----KELTA 148
I Y+ +D+ SPV ++H+ GMT+ +LC AAI SD TAANLLL +GGP T
Sbjct: 107 ITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGGTAAFTG 166
Query: 149 FLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDW 208
+L ++GD V+RLD EPELN P DERDTT P A+A R L DW
Sbjct: 167 YLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDW 226
Query: 209 MEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAL-GPDGKPSRIVVI 259
M + +R+ PA W + DK+G G+ G IA + P G P + V+
Sbjct: 227 MARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVM 278
beta-lactamase (EC 3.5.2.6) precursor - Staphylococcus
aureus
Length = 281
Score = 131 bits (327), Expect = 2e-30
Identities = 82/259 (31%), Positives = 139/259 (53%), Gaps = 5/259 (1%)
Query: 30 KVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQL 89
++ D E + A +G LD SGK ++ F ++RF ST K + +L +V +L
Sbjct: 26 ELNDLEKKYNAHIGVYALDTKSGKEVK-FNSDKRFAYASTSKAINSAILLEQVP--YNKL 82
Query: 90 GRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAF 149
+++H +++D+V YSP+ EK++ +T++ L A++T SDNTA N ++ IGG K++
Sbjct: 83 NKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGIKKVKQR 142
Query: 150 LHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWM 209
L +GD VT R+E ELN P ++DT+ PAA +++ L+D M
Sbjct: 143 LKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKKFLLDLM 202
Query: 210 EADKVAGPLLRSALPAGWFIADKSG-AGERGSRGIIAALGPDGKPSRIVVIYTTGSQATM 268
+K L++ +P + +ADKSG A SR +A + P G+ IV++ T
Sbjct: 203 LNNKSGDTLIKDGVPKDYKVADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKS 262
Query: 269 DERN-RQIAEIGASLIKHW 286
D+ N + I+E S++K +
Sbjct: 263 DKPNDKLISETAKSVMKEF 281
beta-lactamase (EC 3.5.2.6) PER-1 - Pseudomonas
aeruginosa
Length = 308
Score = 73.4 bits (177), Expect = 8e-13
Identities = 58/220 (26%), Positives = 103/220 (46%), Gaps = 14/220 (6%)
Query: 60 PEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVE--YSPVTEKHLTD--GM 115
P E+FPM S FK+ L VL +VD G+ L + + ++ +++ ++P+ + + D +
Sbjct: 63 PFEKFPMQSVFKLHLAMLVLHQVDQGKLDLNQTVIVNRAKVLQNTWAPIMKAYQGDEFSV 122
Query: 116 TVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDE 175
V++L +++ SDN A +LL +GGP L ++ +MG T + E +++
Sbjct: 123 PVQQLLQYSVSHSDNVACDLLFELVGGPAALHDYIQSMGIKETAVVANEAQMHADDQVQY 182
Query: 176 RDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSG- 234
++ T A S+ L WM L+ LPAG +A K+G
Sbjct: 183 QNWTSMKGAAEILKKFEQKTQLSETSQALLWKWMVETTTGPERLKGLLPAGTVVAHKTGT 242
Query: 235 ----AGERGSR---GIIAALGPDGKPSRIVVIYTTGSQAT 267
AG+ + GII L PDG+P + V ++++
Sbjct: 243 SGIKAGKTAATNDLGII--LLPDGRPLLVAVFVKDSAESS 280
beta-lactamase - Bacteroides uniformis
Length = 296
Score = 63.2 bits (151), Expect = 9e-10
Identities = 65/281 (23%), Positives = 114/281 (40%), Gaps = 20/281 (7%)
Query: 8 VALIPFFAAFCLPVFAHPETLVKVKDAEDQL----GARVGYIELDLNSGKILESFRPEER 63
+A++ F C+ + + ++++ D L A VG I + + G +L +
Sbjct: 6 IAILTLFT--CIATVVRAQQMSELENRIDSLLNGKKATVG-IAVWTDKGDMLR-YNDHVH 61
Query: 64 FPMMSTFKVLLCGAVLSRVDAGQEQLGR--RIHYSQNDLVEYSPVTEKHLTDGMTV--RE 119
FP++S FK + AVL ++D L I SQ YSP+ +K T+ RE
Sbjct: 62 FPLLSVFKFHVALAVLDKMDKQSISLDSIVSIKASQMPPNTYSPLRKKFPDQDFTITLRE 121
Query: 120 LCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTT 179
L +I+ SDN A ++L+ GG K + ++H + L E ++ + R+ +
Sbjct: 122 LMQYSISQSDNNACDILIEYAGGIKHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWS 181
Query: 180 MPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGP-LLRSALPAGWFIADKSGAGER 238
P+AM + + D G L+ LPA + K+G+ +R
Sbjct: 182 TPSAMVRLLRTADEKELFSNKELKDFLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDR 241
Query: 239 GSRGIIAA-------LGPDGKPSRIVVIYTTGSQATMDERN 272
+ G+ A + PDG+ I + D N
Sbjct: 242 NADGMKTADNDAGLVILPDGRKYYIAAFVMDSYETDEDNAN 282
beta-lactamase (EC 3.5.2.6) A precursor - Bacteroides
fragilis
Length = 300
Score = 60.1 bits (143), Expect = 7e-09
Identities = 59/231 (25%), Positives = 99/231 (42%), Gaps = 21/231 (9%)
Query: 64 FPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVE--YSPVTEKHLTDG--MTVRE 119
+PMMS FK A+ + ++ L R+ ++DL YSP+ E + G M++ +
Sbjct: 62 YPMMSVFKFHQALALADYMHHQKQPLETRLLIKKSDLKPDTYSPLRETYPQGGIEMSIAD 121
Query: 120 LCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTT 179
L + SDN A ++L GGP + +LH++G + E ++++ + ++ T
Sbjct: 122 LLKYTLQQSDNNACDILFNYQGGPDAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWT 181
Query: 180 MPAAMAXXXXXXXXXXXXXXASRQQLIDWM-----EADKVAGPLLRSALPAGWFIADKSG 234
P A A + + M D++ PLL + G K+G
Sbjct: 182 TPLAAAKLLEIFRNENLFDKEYKNFIYQTMVECQTGQDRLIAPLLDKKVTMG----HKTG 237
Query: 235 AGERGSRG-------IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEI 278
G+R ++G I L PDG I V + S+A E + IAEI
Sbjct: 238 TGDRNAKGQQIGCNDIGFILLPDGHAYSIAV-FVKDSEADNRENSEIIAEI 287
hypothetical protein - Synechocystis sp. (strain PCC
6803)
Length = 495
Score = 50.8 bits (119), Expect = 5e-06
Identities = 52/210 (24%), Positives = 91/210 (42%), Gaps = 14/210 (6%)
Query: 47 LDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPV 106
+D+++G+ + + E + P ST K+ + A VD G+ QL + +Q+ +V +
Sbjct: 235 IDVDNGQFANA-KGETQLPAASTIKIPVAIAFFEAVDQGKIQLHEELPLTQDVIVGEAGT 293
Query: 107 TEKHL--TDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWE 164
+ + E+ + I +SDNTA N+L+ +GG + L T+++ +
Sbjct: 294 MQYDVGKRSSYPALEVVTKMIVISDNTATNMLIKRLGGKEFLNQRFQAWQMPQTKINNYL 353
Query: 165 PELNEAIPNDERDTTMPAAMAXXXXXXXXXXXXXXASRQQLIDWMEADKVAGPLLRSALP 224
P+L + +TT P +A SR +L+ M+ K LL L
Sbjct: 354 PDL------EGTNTTSPQDLALLLVKLQGGELLSLKSRDRLLGIMQQTKTR-TLLPQGLE 406
Query: 225 AGWFIADKSG--AGERGSRGIIAALGPDGK 252
IA K+G G GI+ P+GK
Sbjct: 407 PDAQIAHKTGDIGTVLGDAGIVDM--PNGK 434
beta-lactamase (EC 3.5.2.6) cfxA precursor -
Bacteroides vulgatus transposon Tn4555
Length = 321
Score = 40.6 bits (93), Expect = 0.005
Identities = 44/193 (22%), Positives = 83/193 (42%), Gaps = 13/193 (6%)
Query: 64 FPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDL--VEYSPVTEKHLTD--GMTVRE 119
+PMMS FKV A+ + D L ++ +++ L +SP+ + + +TVR+
Sbjct: 79 YPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTWSPMLKDYSGPVISLTVRD 138
Query: 120 LCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVT-RLDRWEPELNEAIPNDERDT 178
L +T SDN A+NL+ + + +F+ + + ++ E E++ +
Sbjct: 139 LLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQIAYTEEEMSADHNKAYSNY 198
Query: 179 TMPAAMAXXXXXXXXXXXXXXASRQQLIDWME-----ADKVAGPLLRSALPAGWFIADKS 233
T P A + + + ++ D++A PLL G IA K+
Sbjct: 199 TSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIAAPLLDK---EGVVIAHKT 255
Query: 234 GAGERGSRGIIAA 246
G+G G++AA
Sbjct: 256 GSGYVNENGVLAA 268
serine-type D-Ala-D-Ala carboxypeptidase (EC 3.4.16.4)
dacA - Bacillus subtilis
Length = 443
Score = 36.7 bits (83), Expect = 0.081
Identities = 38/132 (28%), Positives = 61/132 (45%), Gaps = 13/132 (9%)
Query: 30 KVKDAEDQLGARVGY-IELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQ 88
K K A D + I ++ +SGKIL S ++R P+ S K++ +L +D G+ +
Sbjct: 28 KAKAASDPIDINASAAIMIEASSGKILYSKNADKRLPIASMTKMMTEYLLLEAIDQGKVK 87
Query: 89 LGRRIHYSQNDLVEYSPVTEKHLT------DG-MTVRELCSAAITMSDNTAANLLLTTIG 141
+ Y+ +D V Y + L+ DG TV+EL A S N AA + +
Sbjct: 88 WDQT--YTPDDYV-YEISQDNSLSNVPLRKDGKYTVKELYQATAIYSANAAAIAIAEIVA 144
Query: 142 GPKELTAFLHNM 153
G + T F+ M
Sbjct: 145 GSE--TKFVEKM 154
signal recognition particle 54K protein homolog -
Aspergillus niger
Length = 534
Score = 32.5 bits (72), Expect = 1.6
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 87 EQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDN 130
+ LGRRI+ + NDL + + EK D M ++E+C+A ++ N
Sbjct: 4 QDLGRRINAAVNDLTRSNNLDEKQAFDDM-IKEICAALLSADVN 46
probable dacB protein - Mycobacterium tuberculosis
(strain H37RV)
Length = 291
Score = 32.5 bits (72), Expect = 1.6
Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 5/99 (5%)
Query: 44 YIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEY 103
+I DL+SG++L P ST KVLL L +D L + D
Sbjct: 45 WIVADLDSGQVLAGRDQNVAHPPASTIKVLLALVALDELD-----LNSTVVADVADTQAE 99
Query: 104 SPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGG 142
T R+L + +S N AAN L +GG
Sbjct: 100 CNCVGVKPGRSYTARQLLDGLLLVSGNDAANTLAHMLGG 138
hypothetical protein AF1138 - Archaeoglobus fulgidus
Length = 554
Score = 31.7 bits (70), Expect = 2.7
Identities = 19/56 (33%), Positives = 25/56 (43%), Gaps = 7/56 (12%)
Query: 223 LPAGWF------IADKSGAGERGSRGIIAALGPDGKPSRI-VVIYTTGSQATMDER 271
LP GW + GERG + + PD KPS + + TT Q TM +R
Sbjct: 463 LPQGWSGEVSPEVIPSVKPGERGEVNLRIRVPPDAKPSEYRITVETTSDQMTMSDR 518
serine-type D-Ala-D-Ala carboxypeptidase (EC 3.4.16.4)
- Bacillus subtilis
Length = 389
Score = 30.9 bits (68), Expect = 4.6
Identities = 20/99 (20%), Positives = 44/99 (44%)
Query: 47 LDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPV 106
++ ++GK+L + ER S K++ ++ +D G+ ++ ++ S++
Sbjct: 43 IERDTGKVLYNKNSNERLAPASMTKIMTMLLIMEALDKGKIKMSDKVRTSEHAASMGGSQ 102
Query: 107 TEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKE 145
+ MTV+E+ S N A+ + I G +E
Sbjct: 103 IFLEPGEEMTVKEMLKGIAIASGNDASVAMAEFISGSEE 141
hypothetical protein Rv1815 - Mycobacterium
tuberculosis (strain H37RV)
Length = 221
Score = 30.9 bits (68), Expect = 4.6
Identities = 14/37 (37%), Positives = 19/37 (50%)
Query: 226 GWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTT 262
GWF E+G G L PDG P++IV I+ +
Sbjct: 157 GWFTMSHGVLSEKGDSGGPVYLAPDGGPAQIVGIFNS 193
hypothetical protein sll0068 - Synechocystis sp.
(strain PCC 6803)
Length = 1239
Score = 30.1 bits (66), Expect = 8.0
Identities = 18/37 (48%), Positives = 22/37 (58%), Gaps = 6/37 (16%)
Query: 209 MEADKVAG---PLLRSALPAGWFI---ADKSGAGERG 239
+E +K+ G PLLRSAL GW I A + G ERG
Sbjct: 414 VEVEKIFGKDSPLLRSALQLGWLIPKTAVRKGVWERG 450
female-specific doublesex protein - fruit fly
(Drosophila melanogaster)
Length = 427
Score = 30.1 bits (66), Expect = 8.0
Identities = 23/67 (34%), Positives = 31/67 (45%), Gaps = 9/67 (13%)
Query: 53 KILESFR-PEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHL 111
K+LE FR P E P+M +L DA E+ RRI Q + EYS ++
Sbjct: 362 KLLEKFRYPWELMPLMYV--------ILKDADANIEEASRRIEEGQYVVNEYSRQHNLNI 413
Query: 112 TDGMTVR 118
DG +R
Sbjct: 414 YDGGELR 420