Molecular interactions on microarrays (1/3) :
1. The
density of oligonucleotides on the surface is :
~ 10 pmol per mm2 on
aminated polypropylene,
~ 0.1 pmol per mm2 on
aminated glass after ammonia deprotection
- equivalent
to one molecule per 39 square angstroms
2. Spacers help to
overcome steric interference