Domains and Sites of the
commonly used signature databases, and has
an intuitive interface for text- and sequence-based searches.
Bioinformatics
infrastructural activities are crucial to modern biological research. Complete and up-to-date databases of biological knowledge are vital for
the increasingly information-dependent
biological and biotechnological research. Secondary protein databases on functional sites and domains like
PROSITE, PRINTS, SMART, Pfam, ProDom, etc. are vital
resources for identifying distant relationships in novel
sequences, and hence for predicting protein function and structure. Unfortunately, these signature databases do not share the
same formats and nomenclature, and each database
has is own strengths and weaknesses.
To capitalise on these, the following partners: EBI, SIB, University of Manchester, Sanger Institute, GENE-IT, CNRS/INRA, LION bioscience AG and University of Bergen unified PROSITE, PRINTS, ProDom and Pfam into InterPro (Integrated resource of Protein Families, Domains and Sites). The latest databases to join the project were SMART, and more recently, TIGRFAMs.
To capitalise on these, the following partners: EBI, SIB, University of Manchester, Sanger Institute, GENE-IT, CNRS/INRA, LION bioscience AG and University of Bergen unified PROSITE, PRINTS, ProDom and Pfam into InterPro (Integrated resource of Protein Families, Domains and Sites). The latest databases to join the project were SMART, and more recently, TIGRFAMs.
Secondarly Protein Sequence Databases
