SWISS-PROT (established 1986) is
a protein sequence database, accessible from the Swiss EMBL Outstation,
EXPASY.
SWISS-PROT excels in
annotation, exhibits very little redundancy and is thoroughly integrated with
other databses. The extensive annotation and exhaustive to reduce redundancy
mean that entries can take time before they are made available, but when they are,
they are a complete and thorough resource. Annotation is updated with
information from published review articles, and by external expert
referees.
The entries are
similar in layout to EMBL entries, with similar two letter codes defining the
contents of each line. These include CC (comment), FT (feature table) and KW (keywords). Annotation includes information about the protein's
function, post-translational modifications, disease associated deficiency,
domains, structure and more. Where applicable, SWISS-PROT entries are cross
referenced with PDB, a database of experimentally determined protein
structure. Three dimensional (3D) models can be viewed with most web browsers,
or files can be downloaded for local viewing.
SWISS-PROT + TrEMBL
