PIR is, in part, a redundant
database. Sequences are made public as soon as the database curators receive
them, even before annotation or classification is verified. Redundancy has
it's disadvantages, most notably the repetition of sequences in different
entries may include discrepencies. The redundancy at PIR can be advantages, as
sequences are made public very quickly. The database is updated weekly.
The PIR-International protein
sequence database is partitioned into four sections: PIR1-PIR4. There is no
clear cut difference between the entries in PIR1 and PIR2.
PIR1
Classified, annotated,
verified and non-redundant with respect to other PIR1 entries.
PIR2
Essentially indistinguishable
from PIR1. Classification may not be quite so extensive as in PIR1.
PIR3
Not classified, annotated or
verified. No attempts have been made to reduce redundancy.
PIR4
Unencoded or untranslated