SWISS-PROT (established 1986) is a protein sequence
database, accessible from the Swiss EMBL Outstation, EXPASY.
SWISS-PROT
excels in annotation, exhibits very little redundancy and is thoroughly
integrated with other databases. The extensive annotation and exhaustive to
reduce redundancy mean that entries can take time before they are made
available, but when they are, they are a complete and thorough resource.
Annotation is updated with information from published review articles, and by
external expert referees.
The
entries are similar in layout to EMBL entries, with similar two letter codes
defining the contents of each line. These include CC (comment), FT (feature table) and KW (keywords). Annotation includes
information about the protein's function, post-translational modifications,
disease associated deficiency, domains, structure and more. Where applicable,
SWISS-PROT entries are cross referenced with PDB, a database of experimentally
determined protein structure. Three dimensional (3D) models can be viewed with
most web browsers, or files can be downloaded for local viewing.