Multiple measurements per patient:
Several spots per tumor sample and several “scores” per spot
Several spots per tumor sample and several “scores” per spot
Each patients (tumor sample) is usually represented
by multiple spots
• 3 tumor spots
• 1 matched normal spot
• Maximum intensity =
Max
• Percent of cells
staining = Pos
• Percent of cells
staining with the
maximum intensity =
PosMax
• Spots have a spot
grade: NL,1,2,..
• Indicator of
missingness