Bioinformatics was born somewhere between
the “old” and “new” biology
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It’s hard to be an expert on 25,000+
genes
In molecular biology cleverness is finding
a way to answer a question definitively by ignoring 99.99% of genes.You can’t see them, so the experiment must exclude them.
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Controls & stats – if you want to see what genes
are changing on a microarray,
you should have some controls – those you expect should change and those that shouldn’t