A protein microarray is a
piece of glass on which different molecules of protein have been affixed at
separate locations in an ordered
manner thus forming a
microscopic array. These are used to identify protein-protein interactions, to
identify the substrates of protein kinases, or to identify the targets of
biologically active small molecules. The most common protein microarray is the
antibody microarray, where antibodies are spotted onto the protein chip and
are used as capture molecules to detect proteins from cell lysate solutions.
Related microarray technologies also include DNA microarrays, Antibody
microarrays, Tissue microarrays and Chemical Compound Microarrays.